The objectives of this 7-year study were to determine the effect of repeated root pruning and irrigation on peach (Prunus persica L. Batsch) tree growth and soil water use. Root pruning began in the year of planting. Peach trees trained to a freestanding “Y” were root-pruned at flowering for 4 years (1985 to 1988) and subsequently at flowering and monthly through July for 3 years (1989 to 1991). Irrigation was withheld or applied the full season or only during stage 3 of fruit growth on root-pruned and non-root-pruned trees. Root pruning limited soil water availability throughout most of the growing season when irrigation was withheld; however, when irrigation was applied, there was no difference in soil water availability. The root length density of peach roots was greatest in the 0 to 30-cm depth, was promoted by irrigation, and was reduced by root pruning in the 0 to 90-cm root zone. Full-season irrigation increased vegetative growth over the nonirrigated treatments. Root pruning had no effect on vegetative growth measured as fresh pruned material. The treatments had no effect on leaf nutrient content, except that root pruning reduced Zn in five consecutive years. Fruit yield was reduced 1 in 5 years by root pruning, and full-season irrigation reduced yield in 3 of 5 years. Repeated root pruning restricted the lateral spread of the root zone and the use of soil resources, yet on the deep soil of this site, restricting the lateral extent of the root zone did not reduce vegetative tree growth.