Editorial1 November 1948RADIOACTIVE IODINE: PHYSIOLOGICAL AND CLINICAL STUDIESM. S. S.M. S. S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-5-965 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince 1946 radioactive isotopes of many varieties have become increasingly available to the investigator and clinician as a result of their release for distribution from the atomic energy pile at Oak Ridge, Tennessee. An upsurge of interest in the diagnostic and therapeutic applications of these agents has occurred. Two among the many available elements, radiophosphorus and radioiodine, have already found a distinct place in the modern therapeutic armamentarium. The behavior of these isotopes, among the earliest to be produced artificially, has been extensively studied in vitro as well as in vivo in animal and human subjects. 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