RADIOACTIVE IODINE: PHYSIOLOGICAL AND CLINICAL STUDIES

Abstract

Editorial1 November 1948RADIOACTIVE IODINE: PHYSIOLOGICAL AND CLINICAL STUDIESM. S. S.M. S. S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-5-965 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince 1946 radioactive isotopes of many varieties have become increasingly available to the investigator and clinician as a result of their release for distribution from the atomic energy pile at Oak Ridge, Tennessee. An upsurge of interest in the diagnostic and therapeutic applications of these agents has occurred. Two among the many available elements, radiophosphorus and radioiodine, have already found a distinct place in the modern therapeutic armamentarium. The behavior of these isotopes, among the earliest to be produced artificially, has been extensively studied in vitro as well as in vivo in animal and human subjects. The data thus obtained...1 JOLIOTCURIE FI: Artificial production of a new kind of radio-element, Nature, 1934, cxxxiii, 201. CrossrefGoogle Scholar2 FERMI E: Radioactivity induced by neutron bombardment, Nature, 1934, cxxxiii, 757. CrossrefGoogle Scholar3 CHAIKOFFTAUROG ILA: Application of radioactive iodine to studies in iodine metabolism and thyroid function. In The Use of Isotopes in Biology and Medicine, 1948, University of Wisconsin Press, Madison. Google Scholar4 MARINE D: Quantitative studies on the in vivo absorption of iodine by dogs' thyroid glands, Jr. Biol. Chem., 1915, xxii, 547. CrossrefGoogle Scholar5 MARINEROGOFF DJM: The absorption of potassium iodide by the thyroid gland in vivo following its intravenous injection in constant amounts, Jr. Pharmacol. and Exper. Therap., 1916, viii, 439. Google Scholar6 HAMILTONSOLEYEICHORN JGMHKB: Deposition of radioactive iodine in human thyroid tissue, Univ. California Publ. Pharmacol. (No. 28), 1940, i, 339. Google Scholar7 WERNERQUIMBYSCHMIDT SCEHC: The clinical use of radioactive iodine, Bull. N. Y. Acad. Med., 1948, xxiv, 549. Google Scholar8 HERTZROBERTSMEANSEVANS SAJHRD: Radioactive iodine as an indicator in thyroid physiology. II. Iodine collection by normal and hyperplastic thyroids in rabbits, Am. Jr. Physiol., 1940, cxxviii, 565. CrossrefGoogle Scholar9 HERTZROBERTS SA: Radioactive iodine as an indicator in thyroid physiology. III. Iodine collection as a criterion of thyroid function in rabbits injected with thyrotropic hormone, Endocrinology, 1941, xxix, 82. CrossrefGoogle Scholar10 LEBLONDGROSSPEACOCKEVANS CPJWRD: Metabolism of radioiodine in the thyroids of rats exposed to high and low temperatures, Am. Jr. Physiol., 1944, cxl, 671. CrossrefGoogle Scholar11 ASTWOOD EB: Treatment of hyperthyroidism with thiourea and thiouracil, Jr. Am. Med. Assoc., 1943, cxxii, 78. CrossrefGoogle ScholarR12 FRANKLINLERNERCHAIKOFF ALSRIL: The effect of thiouracil on the formation of thyroxine and diiodotyrosine by the thyroid of the rat with radioactive iodine as an indicator, Endocrinology, 1944, xxxiv, 265. CrossrefGoogle Scholar13 RAWSONMOOREPEACOCKMEANSCOPERIDDELL RWFDWJHOCB: Effect of iodine on the thyroid gland in Graves' disease when given in conjunction with thiouracil: A two-action theory of iodine, Jr. Clin. Invest., 1945, xxiv, 869. CrossrefGoogle Scholar14 HAMILTONLAWRENCE JGJH: Recent clinical developments in the therapeutic application of radio-phosphorus and radio-iodine, Jr. Clin. Invest., 1942, xxi, 624. Google Scholar15 HERTZROBERTS SA: Application of radioactive iodine in therapy of Graves' disease, Jr. Clin. Invest., 1942, xxi, 624. Google Scholar16 HERTZROBERTS SA: Radioactive iodine as an indicator in the study of thyroid physiology. VII. The use of radioactive iodine therapy in hyperthyroidism, Jr. Am. Med. Assoc., 1946, cxxxi, 81. CrossrefGoogle Scholar17 CHAPMANEVANS EMRD: The treatment of hyperthyroidism with radioactive active iodine, Jr. Am. Med. Assoc., 1946, cxxxi, 86. CrossrefGoogle Scholar18 SOLEYMILLER MHER: Treatment of Graves' disease with radioactive iodine, Med. Clin. N. Am., 1948, 3-17. CrossrefMedlineGoogle Scholar19 KESTONBALLFRANTZPALMER ASRPVKWW: Storage of radioactive iodine in a metastasis from thyroid carcinoma, Science, 1942, xcv, 362. CrossrefGoogle Scholar20 SEIDLINMARINELLIOSBRY SMLDE: Therapeutic effect of radioactive iodine on functioning metastases of thyroid adenocarcinoma, Jr. Am. Med. Assoc., 1946, cxxxii, 838. CrossrefGoogle Scholar21 MARINELLIFOOTEHILLHOCKER LDFWRFAF: Retention of radioactive iodine in thyroid carcinomas: Histopathologic and radio-autographic studies, Am. Jr. Roentgenol., 1947, lviii, 17. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUSE OF RADIOACTIVE IODINE IN THE DIAGNOSIS, STUDY AND TREATMENT OF DISEASES OF THE THYROID 1 November 1948Volume 29, Issue 5Page: 965-972 ePublished: 1 December 2008 Issue Published: 1 November 1948 PDF downloadLoading ...