Use Of Patient-specific Instrumentation Research Articles

Intraoperative Nonpharmacotherapeutic Blood Management Strategies in Total Knee Arthroplasty

Substantial amounts of perioperative blood loss occur during total knee arthroplasty (TKA) that may require allogeneic transfusion in more than 30% of patients. Increased blood loss leads to poor physical functioning, increases infection risks, and prolongs hospitalization, which may eventually affect the overall clinical outcomes of TKA. In addition, allogeneic blood transfusions are associated with increased risks of transfusion reactions, immunosuppression, and a variety of immunological reactions. These concerns have led surgeons and anesthesiologists to develop various strategies to conserve blood, reduce costs, and decrease complications related to blood transfusions. Multiple nonpharmacologic intraoperative blood-saving measures have been used including acute normovolemic hemodilution, hypotensive anesthesia, tourniquets, bipolar sealants, intraoperative blood salvage systems, intramedullary femoral plugs, computer-assisted surgery, and the use of patient-specific instrumentation. However, no clear protocol exists currently to help surgeons choose the appropriate method for blood preservation. The aim of this article was to review the various nonpharmacologic intraoperative blood management strategies that have been used in TKA and to analyze their effectiveness and potential complications according to current evidence.

Multiple Changes Were Needed Despite the Use of Patient-Specific Instrumentation in Total Knee Arthroplasty

Multiple Changes Were Needed Despite the Use of Patient-Specific Instrumentation in Total Knee Arthroplasty

The Use of Patient-Specific Instrumentation Improves the Accuracy of Acetabular Component Placement

Preoperative assessment of acetabular pathology, planning of bone preparation, and implant placement using current imaging, templating, and surgical techniques are imprecise, frequently resulting in component malposition. This study compared the accuracy of 2 surgical approaches: (1) standard preoperative imaging and instrumentation and (2) a novel 3-dimensional computed tomography scan–based preoperative planning software linked to patient- and implant-specific instrumentation (PSI) for placing acetabular components. The PSI group resulted in a significant improvement (P < .05) in the average deviation of implant position (actual vs planned) for version, inclination, and total offset. Fewer clinically relevant screw perforations were observed in the PSI group. This study shows proof of concept and justifies a clinical trial comparing PSI technology with standard surgical techniques.