Biliary diseases refer to the widespread in medical practice. In the absence of primary organic changes in the biliary tract, choledynamic disturbances have a functional nature. However, they usually become the starting point for the progression of pathological processes: metabolic and inflammatory changes in the wall of the gallbladder, onset of biliary sludge and gallstone disease. Holoplant®‑Tau (Propharma Plant, Ukraine) is one of the remedies that make it possible to restore and support the functions of liver, biliary tract and gall bladder. This is a unique hepatocomplex containing artichoke leaf extract 200 mg, angelica root extract 50 mg, ursodeoxycholic acid 100 mg, taurine 100 mg. Owing to the potential of each component, this composition enables achievement of greater effects than the use of large doses of individual medicinal substances. The paper considers therapeutic possibilities of the Holoplant®‑Tau hepatocomplex using clinical examples of patients’ management. The first case concerns hepatic abdominal syndrome; the second presents steatotic liver disease with accompanying chronic cholecystitis with biliary sludge and gastroduodenal pathology. The authors outlined data, that make it possible to confirm the diagnosis and to administer treatment with an assessment of its effectiveness and recommendations to the patients. For each clinical case, the causes and mechanisms of the development of these conditions have been analyzed in detail, and further prognosis was given. It has been concluded that the use of the hepatocomplex Holoplant®‑Tau in biliary disorders is expedient due to its multifaceted effects on the key pathogenetic links of the formation of the group of these diseases and high therapeutic efficiency.