Use In Human Food Research Articles

Phenotypic analysis of the diversity of nine (9) tepary bean (Phaseolus acutifolius) lines by agronomic performance evaluation in Burkina Faso

Tepary bean is a neglected and underutilized grain legume. Tepary bean has a greater potential to cope with the effects of climate change and contribute to food and nutritional security in Burkina Faso. Although it is a versatile legume, its use in human food and as fodder remains poorly understood. It is in this context that this study was initiated at the Gampèla experimental station with a view to improving knowledge of tepary beans by evaluating the agronomic performance of nine (9) lines introduced from Mexico. They were evaluated on seven (7) qualitative variables and fourteen (14) quantitative variables in a randomized complete block design with three (3) replications. The study showed the existence of agronomic variability within the lines studied with regard to qualitative parameters (type of plant, colour of flowering, colour of mature pods, dehiscence of pods, creeping stem, leaflet shape, seed colour) and quantitative parameters (emergence, flowering). Line 13IS-7500 scored highest in pod length (7.9 centimeters); pod weight (0.9 gram); seed length (9.36 centimeters); seed width (9.34 centimeters) and 100-seed weight (15.028 grams). The line 13IS-7500 deserves to be popularised for its seed size and was the best line on yield components.

Applications of chemical bird repellents for crop and resource protection: a review and synthesis

Non-lethal repellents are needed to protect newly planted and ripening crops, to prevent valuable resources from being damaged by some wild birds worldwide. We systematically searched all scientific publications, patents and product registrations to develop a current review and synthesis regarding chemical bird repellents for wildlife researchers, ecologists, managers and conservationists. We then developed a database regarding the testing procedures and repellency results associated with the published and unpublished literature. For this comprehensive database, we developed an ‘index of success’, or relative efficacy level (e.g. effective in most experiments), associated with each tested bird repellent. We found 345 papers published in 1948–2022, including 2994 tests of 1478 repellent chemicals. From 224 publications regarding seed repellents, chemicals that were effective in most experiments and tested in three or more experiments include fungicides (cycloheximide, thiuram), insecticides (carbamates, imidacloprid), starlicide (3-chloro-p-toluidine hydrochloride), human pharmaceuticals (aminopyridine, quinine sulfate), petroleum distillate (paranapthalene), alkaloids (caffeine, quinine sulfate), monoterpenes (d-pulegone) and naturally occurring or synthetic polyphenolic compounds (anthraquinone). Among 114 publications regarding repellents used for foliar/fruit applications, chemicals that were effective in most experiments include activated charcoal, anthraquinone and carbamate. Among other bird repellents that were reportedly effective in most experiments, chemicals used for water applications and tested in three or more experiments include benzaldehyde, ortho-aminoacetophenone and sodium chloride; chemicals used as bait repellents include anthraquinone, methyl anthranilate and 2-carbamoyloxyethyl(trimethyl)azanium chloride; and the single chemical regarded as an area repellent was methyl anthranilate. There are currently 17 registered bird repellent products in the USA for five active ingredients, including anthraquinone, capsaicin, methiocarb, methyl anthranilate and polybutene. Future research and development of chemical bird repellents should include biopesticides (i.e. pesticides derived from natural materials) and pesticides that are already registered for human food use. The future discovery of repellent active ingredients and repellent products can be facilitated by an understanding of the scientific literature, patents and product registrations regarding bird repellent applications summarised in this review.

The Comparison with Commercial Antioxidants, Effects on Colour, and Sensory Properties of Green Tea Powder in Butter.

Oxidation is one of the most important factors limiting shelf life and is a major deterioration process affecting both the sensory and nutritional quality of food. The high oxidation stability of lipids, which can be improved by the addition of antioxidants, is important for health protection, food quality, and economic reasons. In recent years, research on plant-derived antioxidants for use in human health and food has steadily increased. The aim of this study was to compare the antioxidant effects of green tea powder (GTP) in butter with those of commercial antioxidants (BHA, BHT, α-tocopherol, and Trolox). In addition, the effects on colour, sensory, gross physicochemical properties, and β-carotene content were investigated in butter. After the separation of butter into five pieces, the first part was chosen as the control sample without GTP; the second part has 100 mg/kg of BHT added to it; and the third, fourth, and fifth parts had 1, 2, and 3% of GTP added in the samples. They were stored at 4 ± 1 °C. Analysis was performed at intervals of 15 days. According to the iron reduction, CUPRAC and FRAP methods were performed, and parallel results were observed. Using the radical elimination methods (ABTS, DPPH•, and DMPD•+), IC50 values were calculated for the samples. According to the IC50 values, the GTP-containing samples were good antioxidants. The total phenolic andf β-carotene contents increased as the GTP addition increased. The addition of GTP had an antioxidant capacity equal to or higher than that of the BHT-added sample. For the production of a sensory-pleasing, greenish-coloured, new functional butter, the 1% GTP addition showed the most positive results.

Label-Free Quantification by Liquid Chromatography-Tandem Mass Spectrometry of the Kunitz Inhibitor of Trypsin KTI3 in Soy Products.

The greater awareness of consumers regarding the sustainability of food chains has shifted part of the consumption from animal protein sources to vegetable sources. Among these, of relevance both for human food use and for animal feed, is soy. However, its high protein content is unfortunately accompanied by the presence of antinutritional factors, including Kunitz's trypsin inhibitor (KTI). Now there are few analytical methods available for its direct quantification, as the inhibitory activity against trypsin is generically measured, which however can be given by many other molecules and undergo numerous interferences. Therefore, in this work, a direct label-free liquid chromatography-mass spectrometry (LC-MS) method for the identification and quantification of trypsin Kunitz inhibitor KTI3 in soybean and derivative products has been developed. The method is based on the identification and quantification of a marker peptide, specific for the protein of interest. Quantification is achieved with an external calibration curve in the matrix, and the limit of detection and the limit of quantification of the method are 0.75 and 2.51 μg/g, respectively. The results of the LC-MS method were also compared with trypsin inhibition measured spectrophotometrically, highlighting the complementarity of these two different pieces of information.

Physicochemical attributes and bioactive properties of statice leaves

Some ornamental plants have been receiving special attention, not only for their use in landscaping, but also because of their bioactive, aromatic and spicy properties. The objective of this study was to characterize physical and chemical attributes and antioxidant activity in leaves of three cultivars of statice (Limonium sinuatum). The cultivars used were QIS White, QIS Blue Dark, and QIS Yellow. The content of total soluble solids (TSS), total titratable acidity (TTA), TSS/TTA ratio, pH, vitamin C, anthocyanin, flavonoids, total phenolic compounds (TPC), total antioxidant activity (TAA) and the relationship between TPC and flavonoids and TAA were analyzed for each cultivar. The results showed that the leaves of the QIS White cultivar have a higher TSS/TTA ratio, indicating better flavor. The QIS White cultivar also showed higher vitamin C and flavonoid content. The cultivars QIS White and QIS Blue Dark showed higher TPC contents, but there were no differences in TTA and anthocyanin content. The average TAA values were 94.3%, indicating that all cultivars have a high capacity to sequester the DPPH radical. There was a positive relationship between TPC with flavonoids and TAA (R2=0.6168 and 0.8826, respectively). The leaves of statice plants, traditionally used in landscaping and as a cut flower, have potential for use in human food.

Garbage in may not equal garbage out: sex mediates effects of ‘junk food’ in a synanthropic species

AbstractHuman influence on ecosystems is rapidly expanding, and one consequence is the increased availability of human food subsidies to wildlife. Human food subsidies like refuse and food scraps are widely hypothesized to be ‘junk food’ that is nutritionally incomplete; however, the impacts of ‘junk foods’ on the health and fitness of individual organisms remain unclear. In this study, we aimed to understand how human food consumption affects the body condition and fecundity of a generalist predator, the Steller’s jay (Cyanocitta stelleri). We used stable isotope analysis to quantify individual human food consumption (using δ13C as a proxy), estimated individual body condition based on body mass and feather growth bar width and assessed jay fecundity. Adults consumed more human food than juveniles on average, and we observed sex-specific responses to human food use where male body condition tended to increase, whereas female body condition tended to decline with human food consumption. However, fecundity was not strongly related. Thus, we found some evidence for the ‘junk food’ hypothesis in this system, which suggests that human foods may not be an equal replacement for natural foods from a nutritional perspective, especially for females. Human foods tend to be carbohydrate rich, but protein poor, which may benefit males because they are larger and limited overall by calorie intake. Females, particularly reproducing females, are more nutritionally limited and thus may experience fewer benefits from ‘junk food’. Our study advances knowledge of human–wildlife interactions by increasing the resolution of our understanding of the fitness benefits, or detriments, experienced by individuals that consume human foods.

Potential hazards associated with the use of genetically modifi ed organisms in human food

The article provides an analysis of genetically modified organisms. A scheme for their creation is given; genetically modified plants and animals, as well as potential dangers associated with the GMO use in human food are considered.

Human food subsidies drive individual specialization and intrapopulation dietary differences in a generalist predator

AbstractGeneralist species can exhibit individual specialization (IS), where individuals adopt specialized foraging behaviors not attributable to age, sex, or social dominance. While IS increases with the diversity of available foraging resources (ecological opportunity), the potential impact of human food subsidies on ecological opportunity is unknown. We quantified the isotopic niche width of Steller's Jays (Cyanocitta stelleri), a synanthropic predator and dietary generalist, across a gradient of human land‐use categories ranging from subsidized (park campgrounds) to unsubsidized (forest interior) habitats in a protected area in California. We asked (1) if isotopic niche width was better predicted by individual foraging behavior than sex, social dominance, or habitat category (indicating IS) and (2) if degree of IS exhibited by jays increased with the availability of human food subsidies. We characterized the isotopic niche space occupied by individual jays relative to the population using carbon (δ13C) and nitrogen (δ15N) isotope values. Using linear models, we found that jay diet variation was best explained by individual behavior and habitat use rather than by sex or social dominance. While the degree of IS increased with the availability of human foods, individual jays exhibited a variety of foraging behaviors in all habitats that were segregated by foraging stratum and use of human foods. Individual diet also determined the degree of specialization, as jays that specialized on human foods had the narrowest niche width regardless of habitat. Management efforts targeted at generalist wildlife exhibiting large degrees of IS should therefore account for the impact of food subsidies on foraging behavior. Approaches that involve aversive conditioning may fail where highly specialized individuals are unlikely to encounter treatments; therefore, we recommend simultaneous efforts to limit human food subsidies (e.g., information campaigns and improved containment of human food and food waste), and deployment across the largest possible extent of foraging microhabitats and substrates in order to ensure exposure of whole populations to emetic eggs.

Dried orange juice waste as a source of bioactive compounds

PurposeThe waste generated in the process of obtaining orange juice (J) may be used as a natural source of bioactive compounds, thus contributing to the profitability and sustainability of the process. To offer orange J as a dried matter would contribute to the integral valorisation of the J waste and also may expand the field of application.Design/methodology/approachTo find out whether the JW matrix protects the bioactive compounds, the study compares the behaviour of the extracts of the compounds against drying with that resulting from drying the JW for further extraction. Dehydration was carried out at 25 or 50 C and gum Arabic (GA) and bamboo fibre (BF) were used as stabilising biopolymers (Bp). Vitamin C (VC) (L-ascorbic and L-dehydroascorbic acids [AA and DHAA, respectively]) and hesperidin (HES) were analysed before and after the drying.FindingsThe results suggest that to dry the JW gives a higher yield of bioactive compounds, which are also more stable, than when the extract is dried. Furthermore, both the higher temperature and the presence of the Bp favour the extraction of both VC and HES. In this way, all the waste from the orange J-processing industries is converted into a high-value product to be used for cosmeceutical or nutraceutical purposes and also as an ingredient for human food.Social implicationsThe utilisation of organic waste for use in human food, but also in other sectors, is part of the new economic model that aims to do away with the concept of waste as people know it, focussing on a new paradigm in which each resource is a nutrient for nature, industry or society.Originality/valueThe results suggest that to dry the waste gives a higher yield of bioactive compounds, which are also more stable, than when the extract is dried. Furthermore, both the higher temperature and the presence of the Bp favour the extraction of both VC and HES. In that way, all the waste from the orange J-processing industries are converted into a high-value product to be used for cosmeceutical or nutraceutical purposes and also as an ingredient for human food.

Compostos nutricionais e funcionais em flores e raízes de dália

Abstract The use of unconventional edible plants in human food has grown more widespread in recent years, driven mainly by gourmet dishes. Evidence of the food properties of these species is still scarce. Aiming to obtain more in-depth knowledge of dahlia plants, this study aimed to evaluate the nutritional, bioactive, and antinutritional properties of the edible parts of purple dahlia (tuberous root and flower) to elucidate their value and safety as foods. The percent composition, caloric value, pH, Total Soluble Solids (TSS), Total Titratable Acidity (TTA), ratio of TSS to TTA, anthocyanins, carotenoids, vitamin C, total phenolics, tannins, nitrates, and minerals of the roots and flowers were analyzed. The inulin content in the root and the color of the flower were also evaluated. The results were reported as mean and standard deviation, and exploratory factor analysis was performed. Both parts of the dahlia had constituents that contribute to a good diet at concentrations like those in conventional vegetables, whereas the antinutritional components were also compatible with those of commonly consumed foods, with acceptable dietary values. Thus, it is evident that purple dahlia flowers and roots have potential for use in human food and can be considered good options to improve and diversify a healthy diet.

<i>Quassia undulata</i> Oil Exploitation: Extraction’s Yield, Phytochemical Profile of Seeds and Oilcake Nutritional Value

Quassia undulata is a plant that belongs to the Simaroubaceae family. In Africa, it occurs in the wooded savannah from Senegal in the west to the Central African Republic in the east. The seeds from the plant are very rich in oil. The traditional extraction of this oil involves a phase of boiling the powder from the seeds in a decoction of Piliostigma thonningii leaves. Thus, the aim of this study is to determine the impact of Piliostigma thonningii leaves on the extraction yield, to assess the phytochemical profile of seeds and oilcake and, to determine the nutritional value of the cakes obtained after extraction. Thus, the traditional extraction of oil was carried out in the laboratory and physico-chemical and phytochemical analyses were carried out on the water decoction, the oil and, the oilcake. The results showed that the traditional extraction gives a low extraction yield (5.18% with PD and 6.12% without PD) compared to the Soxhlet extraction (56.9%). On the other hand, it was found that oil obtained by traditional extraction in the presence of Piliostigma thonningii leaves was of better physicochemical quality. Finally, oilcake very rich in proteins (36.71% - 42.69%) and mineral elements (110.9 - 152.33 mg/100g of calcium, 544.75 - 620.77 mg/100g of Potassium and 331.11 - 459.68 mg/100g of Magnesium) justify their use in human food. However, investigations should point to the impact of this traditional technique on the elimination of quassinoids, toxins and antihelminth compounds present in the seeds.

Nutritional Characterisation of European Aquaculture Processing By-Products to Facilitate Strategic Utilisation

Sustainability analyses of aquaculture typically ignore the fate and value of processing by-products. The aim of this study was to characterise the nutritional content of the common processing by-products (heads, frames, trimmings, skin, and viscera) of five important finfish species farmed in Europe; Atlantic salmon (Salmo salar), European seabass (Dicentrarchus labrax), gilthead seabream (Sparus aurata), common carp (Cyprinus carpio), and turbot (Psetta maxima) to inform on best utilisation strategies. Our results indicate a substantially higher total flesh yield (64–77%) can be achieved if fully processed, compared to fillet only (30–56%). We found that heads, frames, trimmings and skin from Atlantic salmon, European seabass, gilthead seabream and turbot frames showed medium to high edible yields, medium to high lipid, and medium to high eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) content, indicating significant potential for direct use in human food. By-products which are unattractive for use in food directly but have low ash content and medium to high crude protein, lipid and EPA and DHA content, such as viscera, could be directed to animal feed. Skin showed interesting nutritional values, but has more potential in non-food applications, such as the fashion, cosmetic and pharmaceutical industries. The results indicate potential to increase the direct food, animal feed and non-food value of European aquaculture, without an increase in production volumes or the use of additional resources. The importance of changing consumer perceptions and addressing infrastructure and legislative barriers to maximise utilisation is emphasised.

Human food use increases plant geographical ranges in the Sonoran Desert

AbstractAimClimate is usually regarded as the main determinant of plant species distributions. However, past human use of species for food might also have influenced distributions. We hypothesized that human‐mediated dispersal has resulted in food plants occupying more of their potential geographical range. We also hypothesized that key ecological traits could predispose a species to occupy more of its potential climatic geographical range and be selected by humans for food.LocationThe Sonoran Desert of south‐western North America.Time periodPresent day.Major taxa studiedFood plants.MethodsWe used ethnobotanical data and data from large botanical ecoinformatics databases to estimate realized (dispersal‐ and climate‐constrained) and potential (climate‐constrained) ranges for food plants and their used and unused congeners.ResultsWe found that food plants fill more of their potential geographical ranges than their unused congeners. We also found that succulence and annual growth interacted with food usage to increase range filling.Main conclusionsHuman food use has expanded the distribution of many plant species in the Sonoran Desert.

An application of selected enterococci using Bifidobacterium animalis subsp. lactis BB-12 in set-style probiotic yoghurt-like products

The present study aimed to develop a novel dairy product by combining Bifidobacterium lactis subsp. lactis BB-12® with proven probiotic properties with Enterococcus faecium K67E3 and Enterococcus durans K63E1, which possess potential probiotic properties. Physicochemical, textural and viscosity properties, microbiological, and sensorial attributes of set-style probiotic yoghurt-like products were analysed during the storage at 4 °C for 21 days. The starter culture type had an effect (p < 0.05) on physicochemical, textural and viscosity properties of probiotic yoghurt-like products. High probiotic viability was determined in all samples except for the LD sample containing a combination of Bifidobacterium animalis subsp. lactis BB-12® and Enterococcus durans K63E1. The use of starter culture combination containing Streptococcus thermophilus, Bifidobacterium animalis subsp. lactis BB-12® and Enterococcus durans K63E1 (TLD) in the probiotic yoghurt-like product yielded better textural parameters, apparent viscosity, and improved sensory attributes. Although Enterococcus genera are not thought to be completely safe for use in human food so far, as a result of the research findings, it would be of interest for the dairy industry in the development of novel probiotic dairy products.

Biomass production of the aquatic macrophyte Ceratopteris pteridoides (Hook.) Hieron (Pteridaceae) in nutrient addition treatments

Aquatic macrophytes are a key group in flooded areas due to their high primary productivity, and several species present in the Amazonian floodplains have potential for human food use. This study evaluated biomass production and nutrient levels in fronds of Ceratopteris pteridoides (Pteridaceae), under the following nutritional treatments: (T1) artesian well water, (T2) natural lake water, and (T3) artesian well water with a nutritive solution. Each replicate had 25 plants of 25 g total fresh biomass each. The experiment lasted for 35 days and total fresh biomass weight, root system length, leaf dry biomass weight, root dry biomass weight and sprout number were assessed. The plants from T3 had the greatest increase in total fresh biomass with an average of 430.02 g, showing that the nutritive solution used in the experiment provided the best conditions for plant growth. The daily ingestion of C. pteridoides could contribute to mineral supplementation, in addition to diversifying existing crops and contributing to sustainable agriculture.

Effects of Dietary Cottonseed Oil and Cottonseed Meal Supplementation on Liver Lipid Content, Fatty Acid Profile and Hepatic Function in Laying Hens.

Simple SummaryCottonseed by-products have been considered for use as nutrients in animal diets for a long time. However, the antinutrients, such as free gossypol and cyclopropene fatty acids, from cottonseed have caused numerous adverse effects on animal production. Commonly studies were concentrated on the toxicity of free gossypol, while the toxicity of cyclopropene fatty acids in cottonseed oil was neglected. The current study showed that dietary supplementation of degossypolized cottonseed oil containing cyclopropene fatty acids in diets contributed to dramatic changes in the fatty acid profile in tissues and elevated serum cholesterol level in hens. Therefore, it should raise public concerns about the application of cottonseed oil in both animal and human diets because of its long tradition of use in human food processing.Antinutrients, such as cyclopropene fatty acids (CPFAs) and free gossypol (FG), present together in cottonseed have caused numerous adverse effects on liver health and egg quality of laying hens, which are both likely to be related to a disturbance in lipid metabolism. This experiment employed a 3 × 3 factorial arrangement using corn–soybean-meal-based diets supplemented with different levels of cottonseed oil (0%, 2%, or 4% CSO) containing CPFAs and cottonseed meal (0%, 6%, or 12% CSM) containing FG to elucidate the effects of them or their interaction on fatty acid profile, lipid content, and liver health of laying hens. An overall increase in fatty acid saturation and an overall significant decrease (p < 0.05) in monounsaturated fatty acids (MUFAs) were shown in the livers of hens fed diets with either 2% or 4% CSO. Meanwhile, the concentration of liver cholesterol, serum cholesterol, and serum LDL-c of hens fed a diet supplemented with a high level of CSO (4%) were noticeably increased (p < 0.05). Even though the supplementation of 4% CSO in diets aroused beneficial influences on liver function, a high level of CSO inclusion in laying hens’ diets is not recommended due to its hypercholesterolemia effect. In conclusion, supplementation of CSO, which contains 0.20% CPFAs, was the primary cause of alteration in fatty acid composition and cholesterol content in hens, while no interaction between CSM and CSO nor CSM effect was found for lipid profile and liver health in laying hen.

Natural non-nutritive but healthier sweeteners

Globally, the increasing adverse health effects of excessive consumption of natural nutritive sweeteners have lead to a significant interest in non-nutritive sweeteners (NNS) among all age groups. The NNS approved by Food Safety and Standards Authority of India (FSSAI) has higher sweetness intensity than natural nutritive sugar. NNS when added to food they provide negligible calories and a promising healthier alternative to nutritive sweeteners for the dietary management of noncommunicable diseases. FSSAI has approved six non-nutritive artificial sweeteners (saccharin, aspartame, sucralose, isomaltulose, neotame, and acesulfame potassium) for use in human food. Besides their benefits, metabolic products of these artificial sweeteners have found controversial health effects over animal studies. Therefore, intensive research activities are being devoted by scientists all over the world to find less controversial, plant-derived, organic zero-calorie or low calorie, and non- carcinogenic NNS which provides consumer a better choice to satisfy their innate desire for a sweet taste without adding calories. This review highlights natural NNS, including their sensory property, structural characteristics, and specific compounds contributing to their sweetness, uses, and food applications. The steviol glycoside is the only natural NNS that has been approved by FSSAI.

Gabiroba e Murici: Estudo do valor nutricional e antinutricional da casca, polpa e semente

Os frutos do murici e gabiroba são comuns no Cerrado Brasileiro, mas seu consumo é limitado não só pela região, mas também por serem frutos sazonais e perecíveis. Assim, esse trabalho teve a intenção de caracterizar física, química, nutricional e antinutricionalmente as frações casca, polpa e semente para utilização, pela indústria alimentícia, dos frutos inteiros ou suas frações. Foram realizadas analises de diâmetro horizontal, transversal e massa nos frutos inteiros, e nas frações as seguintes analises (Aw, cor, sólidos solúveis, pH, acidez titulável, umidade, proteína, lipídios, cinzas, carboidratos, valor calórico, antioxidantes (DPPH, FRAP, e fenólicos), vitamina C, compostos cianogênios, fitatos e taninos, onde os resultados obtidos foram tabelados apresentados juntamente com desvio padrão e realizado uma análise de variância nas medias. Os resultados mostraram que em ambos os frutos e, dependendo de suas frações, encontram-se teores significativos de proteínas e vitamina C, além de possuírem atividade antioxidante. Na casca e semente dos frutos de murici e gabiroba não foram encontrados teores de inibidores de proteases, glicosídeos cianogênios tão pouco de fitatos; a presença de taninos não compromete a utilização na alimentação humana, apenas necessita-se de cuidados na incorporação e ingestão com alimentos ricos em cálcio e magnésio. Logo, a inserção das frações casca, polpa e semente dos frutos murici e gabiroba, em produtos alimentícios, é viável, contribuindo-lhes com agregação de valor e colaborando com a redução do lixo orgânico.

Med Check: Sage’s Treatment; Cannabidiol Products; Pimavanserin; Cognitive Supplements

Med Check: Sage’s Treatment; Cannabidiol Products; Pimavanserin; Cognitive Supplements

Boom or bust ahead for cannabidiol in the US?

Cannabidiol (CBD), a chemical found in cannabis, is popping up in all sorts of consumer products sold in the US, including lotions, tinctures, dietary supplements, food, beverages, and pet food. The US Food and Drug Administration has for several years been pondering ways to make it legal to market CBD in products regulated by the agency. Most of the CBD in products sold in the US today is derived from hemp, a cannabis strain that contains less than 0.3% of the psychoactive ingredient tetrahydrocannabinol, or THC. Nevertheless, the majority of such products are illegal because they don’t comply with the Federal Food, Drug, and Cosmetic Act. The FDA said late last year that it does not consider CBD generally recognized as safe for use in human or animal food, so it can’t be legally added to food without premarket approval from the FDA. The agency also said it is illegal