BackgroundSoft skills and flipped classrooms are important in the fields of education, nursing, and health techniques. AimThis study determined nursing teachers’ knowledge of soft skills and flipped classrooms. DesignThis was a descriptive cross-sectional study with an analytical focus involving 100 teachers. SettingsThe study was conducted at the Higher Institute of Nursing Professions and Health Techniques (ISPITS) at Agadir and its annex in Tiznit. ParticipantsOne hundred permanent and temporary teachers (with an equal distribution of male and female teachers) participated in the survey. MethodsA five-part questionnaire was used to collect data. The independent variable was the use of a flipped classroom and dependent variable was the development of soft skills. SPSS version 25 software was used to process the data. Chi-square test, Ficher's test, binary logistic regression test, and multivariate logistic regression model were employed for data analysis. ResultsIn total, 80 % participants had knowledge of soft skills, and 75 % knew about flipped classrooms. The most important soft skills were considered to be communication, stress management, teamwork, conflict management, problem-solving, time management, critical thinking, autonomy, adaptability, and decision-making. The five soft skills considered most likely to be developed by flipped classrooms were autonomy, analysis, teamwork, communication, and time management. Furthermore, the development of soft skills through the flipped classrooms was independently associated with soft skills training (p = 0.008) and use of flipped classrooms (p = 0.042). ConclusionsTeachers have knowledge of soft skills and flipped classrooms despite a lack of training, and flipped classrooms contribute to the development of soft skills.