US Authors Research Articles

Participant Contributions to Person-Generated Health Data Research Using Mobile Devices: Scoping Review.

Mobile devices offer an emerging opportunity for research participants to contribute person-generated health data (PGHD). There is little guidance, however, on how to best report findings from studies leveraging those data. Thus, there is a need to characterize current reporting practices so as to better understand the potential implications for producing reproducible results. The primary objective of this scoping review was to characterize publications' reporting practices for research that collects PGHD using mobile devices. We comprehensively searched PubMed and screened the results. Qualifying publications were classified according to 6 dimensions-1 covering key bibliographic details (for all articles) and 5 covering reporting criteria considered necessary for reproducible and responsible research (ie, "participant," "data," "device," "study," and "ethics," for original research). For each of the 5 reporting dimensions, we also assessed reporting completeness. Out of 3602 publications screened, 100 were included in this review. We observed a rapid increase in all publications from 2016 to 2021, with the largest contribution from US authors, with 1 exception, review articles. Few original research publications used crowdsourcing platforms (7%, 3/45). Among the original research publications that reported device ownership, most (75%, 21/28) reported using participant-owned devices for data collection (ie, a Bring-Your-Own-Device [BYOD] strategy). A significant deficiency in reporting completeness was observed for the "data" and "ethics" dimensions (5 reporting factors were missing in over half of the research publications). Reporting completeness for data ownership and participants' access to data after contribution worsened over time. Our work depicts the reporting practices in publications about research involving PGHD from mobile devices. We found that very few papers reported crowdsourcing platforms for data collection. BYOD strategies are increasingly popular; this creates an opportunity for improved mechanisms to transfer data from device owners to researchers on crowdsourcing platforms. Given substantial reporting deficiencies, we recommend reaching a consensus on best practices for research collecting PGHD from mobile devices. Drawing from the 5 reporting dimensions in this scoping review, we share our recommendations and justifications for 9 items. These items require improved reporting to enhance data representativeness and quality and empower participants.

Robotics, money and research: is data or physician payments driving robotic bariatric surgery literature?

Physician payments from Intuitive Surgical have increased from 37 million to over 53 million per year since 2018. The study was completed to determine the accuracy of conflict of interest (COI) statements and the influence of industry payments on the valuation of the robotic platform. PubMed and Medline search for "robotic, robotic assisted" and "bariatric, Gastric Bypass, Sleeve Gastrectomy, Biliopancreatic Diversion, and Single Anastomosis Duodeno-Ileal Bypass". Manuscripts on robotic bariatric surgery with a US author with an electronic publication (EPub) date between 2018 and 2022 were included. Manuscripts were reviewed for disclosure of COI. The manuscripts were reviewed by two reviewers. The Introduction, Results, and Discussion/Conclusion were scored as Robotic Unfavorable, Neutral, or Robotic Favorable. https://OpenPaymentsData.CMS.gov was reviewed for physician payments 1year prior and 1year following the EPub date. Robotic favorable manuscripts were significantly less likely to have an adequate COI. Authors of robotic favorable manuscripts were significantly more likely to have a COI. Authors of robotic favorable manuscripts had significantly a higher Intuitive physician compensation. In addition, authors of robotic favorable manuscripts were significantly more likely to have an increase in the amount of compensation by Intuitive Surgical the following year. Our findings suggest thatIntuitive open payments have significantly influenced favorable reports inrobotic bariatricliterature. The submission of open paymentsdata, to include compensation amounts should be required for manuscript publication or acceptance to surgical conferences.

An empirical study of retractions due to honest errors: Exploring the relationship between error types and author teams

By adopting binary logistic regression and using a dataset of retractions due to honest errors, this paper analyses the relationships between types of honest errors and the characteristics of author teams, aiming to make recommendations about research management for researchers and policy makers. The results show that (1) honest errors made by medium-sized teams are more likely to be data errors rather than other types of errors, than those made by other-sized teams; (2) overall, there is no obvious relationship between types of honest errors and collaboration patterns; (3) there is no significant difference in the probability that honest errors are data errors rather than other types of errors (called “the probability”), with or without the participation of US authors. Honest errors made by teams with the participation of Chinese authors are less likely to be data errors, than those made by teams without Chinese authors; (4) collaboration patterns moderate the relationship between types of honest errors and the participation of Chinese authors. Specifically, the probability is significantly greater for single-authored publications in China than in other countries, and the probability for domestic collaboration in China is much lower than that outside China. There is no significant difference in the probability for international collaboration publications in China and those in other countries.

Bibliometric Analysis to Improve Combined Treatment Strategies for Glioblastoma in America

Introduction: Bibliometric analysis quantitatively examines scientific literature to extract insights. This article has conducted such analysis on glioblastoma multiforme (GBM) treatment articles. GBM, a prevalent brain tumor, is typically treated with surgery, radiation, and chemotherapy. Objectives: The article aimed to bibliometrically analyze articles discussing combined GBM treatment to identify impactful research areas and encourage collaboration. Materials and Methods: The study encompassed a comprehensive search in the Scopus database, spanning articles published from 1974 to 2022. Inclusion criteria encompassed research conducted in the Americas, both clinical and experimental. A total of 772 articles were collected and categorized based on their primary focus on combined treatment approaches. Results: Clinical studies constituted 52% of articles, suggesting a slight dominance. The analysis unveiled key research moments, including a 1998 focus shift and a pivotal 2005 study on temozolomide- radiation combination. Top journals, trends, and authors were identified, with the USA leading in contributions. Discussions: Despite high brain tumor incidence, research distribution discrepancy is concerning. Regional epidemiological studies have been endorsed. The dominance of US and German authors in GBM collaboration has raised equity issues due to budget and GDP disparities limiting Latin American representation. Conclusion: GBM research in the region is dominated by the USA, while contributions from Latin American countries remain limited. The absence of comprehensive epidemiological studies on GBM in Latin America is concerning, considering the evident impact of the disease in the region. This underscores the urgent need for increased research participation and collaboration to advance the understanding and treatment of GBM across Latin American nations.

Assessment of conflicts of interest in literature on monoclonal antibodies for chronic rhinosinusitis with nasal polyposis using the Open Payments Database.

Accurate conflict of interest (COI) information is essential for promoting transparency and trust in research. We aim to assess COI disclosure patterns in monoclonal antibodies (MABs) research for chronic rhinosinusitis with nasal polyposis (CRSwNP) using the Open Payments Database (OPD). Studies on FDA-approved MABs for CRSwNP (dupilumab, omalizumab, mepolizumab) published between 2019 and 2021 with at least one US author were identified through PubMed. Industry-reported payments from the manufacturers (Sanofi, Regeneron, Genentech, Novartis, and GlaxoSmithKline) between 2018 and 2021 in OPD's General Payments category were collected. Authors were cross-checked against OPD metadata using a previously published ChatGPT-based algorithm. Additionally, this novel algorithm analyzed COI statements for relevant author‒company specific disclosures, identifying disclosed and undisclosed payments made 3‒15 months prior to publication. A total of 214 unique authors from 76 studies were included. Of 30 articles that received at least one relevant payment, 21 (70%) were found to have an undisclosed COI, with a mean total undisclosed payment of $4890 and a median of $10,331. Fifty-six authors had relevant OPD payments and 40 (71.4%) authors did not declare a potential COI. Interestingly, 158 authors had no relevant payments and 62 (39.2%) declared a potential COI. Author order was not significantly associated with potential under- or over-disclosure. This study characterizes COI disclosure patterns in rhinosinusitis-relevant MABs research using a novel automated approach. Given the discrepancy between disclosures and industry-reported payments, our findings suggest a need for improved disclosure education and practices.

Mobilizing Literature: Social Movements and Post-1945 US Literary Studies

Abstract: This essay proposes a movements-based method for studying the development of US literature after World War II. It argues that the cultural materialist and institutionalist frameworks that have dominated post-1945 US literary studies in recent years have systematically overlooked the role of social movements as catalysts for cultural change. Through readings of the literary magazine n+1, the archival materials of Octavia Butler, and novels by a range of other major postwar US authors, it offers an account of how the collective mobilizations of the past sixty years—from Civil Rights, the New Left, and the Women's Movement to Occupy Wall Street, Black Lives Matter, and #MeToo—have decisively shifted the contours of the US literary field.

Perceived context typicality and beliefs in the generalizability of management research findings

Despite growing calls for a greater internationalization of management research, the discipline still struggles with the challenge of integrating diverse national contexts. While recent decades have seen a change toward a more equitable treatment of all national contexts, the belief that research conducted outside the United States is less generalizable remains strong. In this research note, we explore the general perceptions of what is considered a “typical” study context by associating them with authors' variable tendencies to report threats to external validity. Using a sample of 400 papers from seven top-tier management journals, we find that research based on non-US data tends to report more external validity threats, which makes it appear less generalizable. While the belief that the US constitutes a “typical” study context is shared by both US and non-US author teams, non-US co-authors tend to exhibit a relatively stronger bias against the generalizability of non-US samples in their studies. Collectively, our results contribute to the literature on external validity threats, generalizability, and biases in peer review, while also responding to recent calls for a more diverse and inclusive management research program.

Financial Conflicts of Interest Among Physician Authors of ACR Appropriateness Criteria

BackgroundThe accuracy and completeness of self-disclosures by authors of imaging guidelines are not well known. ObjectiveThe aim of this study was to assess the accuracy of financial disclosures by US authors of ACR appropriateness criteria. MethodsWe reviewed financial disclosures provided by US-based authors of all ACR-AC published in 2019, 2021 and 2023. For each US- based author, payment reports were extracted from the Open Payments Database (OPD) in the previous 36 months related to general category and research payments categories. We analyzed each author individually to determine if the reported disclosures matched results from OPD. ResultsA total of 633 authorships, including 333 unique authors were included from 38 ACR AC articles in 2019, with 606 authorships (387 unique authors) from 35 ACR-AC articles published in 2021, and 540 authorships (367 unique authors) from 32 ACR AC articles published in 2023. Among authors who received industry payments, failure to disclose any financial relationship was seen in 125/147 unique authors in 2019, 142/148 authors in 2021 and 95/125 unique authors in 2023. The proportion of nondisclosed total value of payments was 86.1% in 2019, 88.6% in 2021 and 56.7% in 2023. General category payments were nondisclosed in 94.1% in 2019, 89.7% in 2021 and 94.4% in 2023 by payment value. ConclusionIndustry payments to authors of radiology guidelines are common and frequently undisclosed.

ChatGPT for Automated Cross-Checking of Authors' Conflicts of Interest Against Industry Payments.

The Centers for Medicare & Medicaid Services "OpenPayments" database tracks industry payments to US physicians to improve research conflicts of interest (COIs) transparency, but manual cross-checking of articles' authors against this database is labor-intensive. This study aims to assess the potential of large language models (LLMs) like ChatGPT to automate COI data analysis in medical publications. An observational study analyzing the accuracy of ChatGPT in automating the cross-checking of COI disclosures in medical research articles against the OpenPayments database. Publications regarding Food and Drug Administration-approved biologics for chronic rhinosinusitis with nasal polyposis: omalizumab, mepolizumab, and dupilumab. First, ChatGPT evaluated author affiliations from PubMed to identify those based in the United States. Second, for author names matching 1 or multiple payment recipients in OpenPayments, ChatGPT undertook a comparative analysis between author affiliation and OpenPayments recipient metadata. Third, ChatGPT scrutinized full article COI statements, producing an intricate matrix of disclosures for each author against each relevant company (Sanofi, Regeneron, Genentech, Novartis, and GlaxoSmithKline). A random subset of responses was manually checked for accuracy. In total, 78 relevant articles and 294 unique US authors were included, leading to 980 LLM queries. Manual verification showed accuracies of 100% (200/200; 95% confidence interval [CI]: 98.1%-100%) for country analysis, 97.4% (113/116; 95% CI: 92.7%-99.1%) for matching author affiliations with OpenPayments metadata, and 99.2% (1091/1100; 95% CI: 98.5%-99.6%) for COI statement data extraction. LLMs have robust potential to automate author-company-specific COI cross-checking against the OpenPayments database. Our findings pave the way for streamlined, efficient, and accurate COI assessment that could be widely employed across medical research.

Accuracy of Financial Disclosures in Radiology Journals

PurposeThe accuracy and completeness of self-disclosures of the value of industry payments by authors publishing in radiology journals are not well known. The aim of this study was to assess the accuracy of financial disclosures by US authors in five prominent radiology journals. MethodsFinancial disclosures provided by US-based authors in five prominent radiology journals from original research and review articles published in 2021 were reviewed. For each author, payment reports were extracted from the Open Payments Database (OPD) in the previous 36 months related to general, research, and ownership payments. Each author was analyzed individually to determine if the reported disclosures matched results from the OPD. ResultsA total of 4,076 authorships, including 3,406 unique authors, were selected from 643 articles across the five journals; 1,388 (1,032 unique authors) received industry payments within the previous 36 months, with a median total amount received per authorship of $6,650 (interquartile range, $355-$87,725). Sixty-one authors (4.4%) disclosed all industry relationships, 205 (14.8%) disclosed some of the OPD-reported relationships, and 1,122 (80.8%) failed to disclose any relationships. Undisclosed payments totaled $186,578,350, representing 67.2% of all payments. Radiology had the highest proportion of authorships disclosing some or all OPD-reported relationships (32.3%), compared with the Journal of Vascular and Interventional Radiology (18.2%), the American Journal of Neuroradiology (17.3%), JACR (13.1%), and the American Journal of Roentgenology (10.3%). ConclusionsFinancial relationships with industry are common among US physician authors in prominent radiology journals, and nondisclosure rates are high.

Clinical Research in Renal Transplantation: A Bibliometric Perspective on a Half-century of Innovation and Progress.

Groundbreaking biomedical research has transformed renal transplantation (RT) into a widespread clinical procedure that represents the mainstay of treatment for end-stage kidney failure today. Here, we aimed to provide a comprehensive bibliometric perspective on the last half-century of innovation in clinical RT. The Web of Science Core Collection was used for a comprehensive screening yielding 123 303 research items during a 50-y period (January 1973-October 2022). The final data set of the 200 most-cited articles was selected on the basis of a citation-based strategy aiming to minimize bias. Studies on clinical and immunological outcomes (n = 63 and 48), registry-based epi research (n = 38), and randomized controlled trials (n = 35) dominated the data set. Lead US authors have signed 110 of 200 articles. The overall level of evidence was high, with 84% of level1 and -2 reports. Highest numbers of these articles were published in New England Journal of Medicine , Transplantation , and American Journal of Transplantation. Increasing trend was observed in the number of female authors in the postmillennial era (26% versus 7%). This study highlights important trends in RT research of the past half-century. This bibliometric perspective identifies the most intensively researched areas and shift of research interests over time; however, it also describes important imbalances in distribution of academic prolificacy based on topic, geographical aspects, and gender.

US-Cyberpunk und Cyber-Japan. Zwischen Blade Runner, Neuromancer und Die Hard

The paper explores why US authors of the cyberpunk genre imagined a future rich in Japanoid imagery in their fiction. By tracing the zeitgeist of the 1980s, which was characterized by the prevalence of affordable Japanese technology in everyday US life – often associated with fears of an economic threat from Japan – it is possible to explain why cyberpunk fictions explicitly depict Japanese technology. Furthermore, mechanisms of techno-orientalism that link high-tech to images of premodern Japan and thus diminish this specific cultural environment as subordinate to modern Western societies are evident within cyberpunk fiction. Analyzing Ridley Scott’s Blade Runner (1982) as a founding text of cyberpunk and the recent computer game Cyberpunk 2077 (2020) as well as the subsequent anime series Cyberpunk Edgerunners (2022) as examples of contemporary fiction, I argue that Japanoid images continue to be employed in a condescending manner within the cyberpunk genre, affirming an inherently Western perspective.

The relationship between interdisciplinarity and citation impact—a novel perspective on citation accumulation

Interdisciplinary research is of significance for creating breakthroughs and facilitating innovations and may achieve higher citation impact, although contrary results still exist. The current study looks into the relationship between interdisciplinarity and citation impact from a brand-new perspective—the process of citation accumulation—by exploring how interdisciplinarity, as measured by Rao-Stirling and DIV, affects the accumulating process of citations, based on scientific papers published by Chinese or US authors in 2009–2011 in Chemistry. Two metrics are used to measure how long it takes for a paper to reach its citation peak (PEAK_YEAR) and how sustainable the citation impact remains after the peak (SUS). The results show that compared with Rao-Stirling, DIV is more sensitive to the length of the citation window and more closely aligned with the nature of interdisciplinarity. In Chemistry, higher interdisciplinarity is more likely to encounter delayed recognition and greater citation sustainability, which may explain the inconsistency in the relationship between interdisciplinarity and citation impact. In conclusion, it is necessary to consider the length of the citation window when explaining the relationship between interdisciplinarity and citation impact. A longer citation window may be a better solution, as an alternative or supplement, in assessing the academic performance of interdisciplinary research.

Growth and dimensions of monkeypox research: a scientometrics study

Purpose This study aims to analyse the trend of Mpox research in the pre and post-outbreak period. The study compared the growth pattern, major research areas, sources of publications, funding agencies, countries and institutions invested in Mpox research, and institutional and countrywide collaboration patterns in Mpox research in both periods. Design/methodology/approach This study is based on the data retrieved from the Web of Science database for two time frames: the pre-outbreak period (January 1989–April 2022) and the post-outbreak period (May 2022–December 2022). The study is limited to research articles and reviews articles from Web Science. The study used Microsoft Excel and VOSviewer visualization software to derive results. Findings The study found few publications on Mpox before the epidemic outbreak, and a steep increase is visible after it. Before and after the Mpox pandemic, the USA ranked first in the production of literature. The focus of research before the outbreak of the epidemic was on virology, which was replaced by infectious diseases during the post-epidemic period. More publications were found available in open-access journals during the post-outbreak time. Author collaboration with US authors from other countries is higher in the post-outbreak period. During the pre-outbreak time, the principal supporters of Mpox research were American funding agencies and institutes. The study reveals that the research in post-outbreak is more concentrated on diagnosis, prevention and treatment of Mpox. Practical implications This study offers a systematic literature review on Mpox’s overall research productivity. It contrasted the patterns of this field’s pre- and post-epidemic research. The conclusions of this study will act as a guide for scientists operating all across the world. Originality/value A thorough scientometric analysis of the trend of Mpox research in the pre- and post-outbreak period has not been attempted. It will help identify the nature of research on Mpox over the years, which will support future research on Mpox attempted across the globe.

Knowledge mapping of immunotherapy in castration-resistant prostate cancer: a bibliometric and visualized study (2003–2022)

ObjectiveTo utilize bibliometric analysis to examine the literature about immunotherapy for castration-resistant prostate cancer published within the past two decades. Through this method, we aim to visualize and analyze the research progress in this field and identify the most recent trends and developments.MethodsThis research conducted a comprehensive literature review on immunotherapy for castration-resistant prostate cancer. The time frame spanned from January 2003 to December 2022, and the data were extracted from the Web of Science Core Collection database. The application of various software tools, such as CiteSpace, Bibliometrix, and VOSviewer, facilitated the visualization and analysis of the gathered data. These technological utilities illustrated the progression of prominent focus areas within the field.ResultsAfter excluding irrelevant studies, 373 papers were selected for this study. The findings suggested that the field of immunotherapy for castration-resistant prostate cancer was rapidly developing. The USA was considered to have a significant early entrant advantage in this area and profoundly influenced the field. Similarly, China’s National Cancer center demonstrated notable advantages as a recent participant in this research domain. Major research institutions contributing to the field include the University of California, San Francisco; the University of Washington; and the Memorial Sloan Kettering Cancer Research Center. Notably, US authors James L. Gulley, Charles G. Drake, and Lawrence Fong had the largest number of publications in this area. The main research trends for immunotherapy of castration-resistant prostate cancer are membrane antigen expression, checkpoints T-lymphocyte-associated protein 4 (CTLA4) blockade, radium-223, and vaccines, and the refinement of establishing organoid models might fuel castration-resistant prostate cancer immunotherapy research in the ongoing development.ConclusionThe key trends in immunotherapy research for castration-resistant prostate cancer are membrane antigen expression, CTLA4 blockade, radium-223, and vaccines. Exploring new immune pathways and combining different therapeutic approaches to enhance immune response will be a major trend in the field in the future.

Global trends and frontiers in research on exercise training for heart failure: a bibliometric analysis from 2002 to 2022.

Heart failure is a common cardiovascular disease that imposes a heavy clinical and economic burden worldwide. Previous research and guidelines have supported exercise training as a safe, effective, and cost-efficient treatment to intervene in heart failure. The aim of this study was to analyze the global published literature in the field of exercise training for heart failure from 2002 to 2022, and to identify hot spots and frontiers within this research field. Bibliometric information on literature on the topic of exercise training for heart failure published between 2002 and 2022 was searched and collected in the Web of Science Core Collection. CiteSpace 6.1.R6 (Basic) and VOSviewer (1.6.18) were applied to perform bibliometric and knowledge mapping visualization analyses. A total of 2017 documents were retrieved, with an upward-stable trend in the field of exercise training for heart failure. The US authors were in the first place with 667 documents (33.07%), followed by Brazilian authors (248, 12.30%) and Italian authors (182, 9.02%). The Universidade de São Paulo in Brazil was the institution with the highest number of publications (130, 6.45%). The top 5 active authors were all from the USA, with Christopher Michael O'Connor and William Erle Kraus publishing the most documents (51, 2.53%). The International Journal of Cardiology (83, 4.12%) and the Journal of Applied Physiology (78, 3.87%) were the two most popular journals, while Cardiac Cardiovascular Systems (983, 48.74%) and Physiology (299, 14.82%) were the two most popular categories. Based on the results of keyword co-occurrence network and co-cited reference network, the hot spots and frontiers of research in the field of exercise training for heart failure were high-intensity interval training, behaviour therapy, heart failure with preserved ejection fraction, and systematic reviews. The field of exercise training for heart failure has experienced two decades of steady and rapid development, and the findings of this bibliometric analysis provide ideas and references for relevant stakeholders such as subsequent researchers for further exploration.

Discussion on Covid-19 and International Relations: VOSviewer Bibliometric Analysis of Articles by US and Chinese Authors

The initial emergence of the coronavirus which made the Covid-19 Pandemic in Wuhan, China, made the international world of countries coordinate and cooperate with each other to deal with the pandemic. The Chinese government is accelerating in fighting the pandemic by providing medical assistance, cooperating with other countries, and actively promoting community-building with a shared future for humanity and the process of globalization. Different state policies in handling it make researchers determined to carry out research whose articles have been published by Scopus to become material for study and policy. This study aims to explain writing trends and characteristics of International Relations and Covid-19 conducted by authors from the United States and China. In this study using the VOSviewer bibliometric analysis method, a study conducted by researchers found that the trend of Scopus-indexed journal articles from authors in the United States and China had grown quite significantly until 2022.

Challenging the Myth of the Digital Native: A Narrative Review

Nurses are increasingly engaging with digital technologies to enhance safe, evidence-based patient care. Digital literacy is now considered a foundational skill and an integral requirement for lifelong learning, and includes the ability to search efficiently, critique information and recognise the inherent risk of bias in information sources. However, at many universities, digital literacy is assumed. In part, this can be linked to the concept of the Digital Native, a term first coined in 2001 by the US author Marc Prensky to describe young people born after 1980 who have been surrounded by mobile phones, computers, and other digital devices their entire lives. The objective of this paper is to explore the concept of the Digital Native and how it influences undergraduate nursing education. A pragmatic approach was used for this narrative review, working forward from Prensky's definition of the Digital Native and backward from contemporary sources of information extracted from published health, education and nursing literature. The findings from this narrative review will inform further understanding of digital literacy beliefs and how these beliefs influence undergraduate nursing education. Recommendations for enhancing the digital literacy of undergraduate nursing students are also discussed. Digital literacy is an essential requirement for undergraduate nursing students and nurses and is linked with safe, evidence-based patient care. The myth of the Digital Native negates the reality that exposure to digital technologies does not equate digital literacy and has resulted in deficits in nursing education programs. Digital literacy skills should be a part of undergraduate nursing curricula, and National Nursing Digital Literacy competencies for entry into practice as a Registered Nurse should be developed and contextualised to individual jurisdictions.

Retrospective and Prospective Analysis on “Sexting”: Indicators of Productivity, Dispersion, and Content (2009–2019)

In the last decade, research on “sexting” has undergone an exponential increase, giving rise to the publication of numerous studies clarifying its meaning, offering information of educational value, and favoring a good use of technology to prevent problems caused by this exchange of sexual information. The aim of this article was to analyze the production, performance, impact, and content of scientific articles evaluating the “sexting” thesaurus (title, abstract, and/or keywords) between 2009 and September 2019. Articles were sourced from two internationally recognized databases: Scopus and Web of Science. A scientometric study was then carried out on a sample of 641 articles that met the established inclusion criteria. The main findings indicate that “sexting” is a very recent research focus, but one in full growth phase, with scientific production related to the topic likely to double over the next few years. Although “sexting” has been researched worldwide, the scientific production of the US and American authors is the most notable. There were also some differences between the Scopus and Web of Science databases, mainly in the volume of production and the trend. However, the studies do show a common research line, “cyberbullying,” and a common target population: adolescents. Therefore, the content analysis reveals that research on “sexting” is mostly carried out with adolescents and takes into consideration other themes such as cyberbullying, dating violence, and sexuality.

Clinical Treatment Guidelines for Tafasitamab Plus Lenalidomide in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma.

Diffuse large B-cell lymphoma (DLBCL) accounts for approximately 24% of new cases of B-cell non-Hodgkin lymphoma in the US each year. Up to 50% of patients relapse or are refractory (R/R) to the standard first-line treatment option, R-CHOP. The anti-CD19 monoclonal antibody tafasitamab, in combination with lenalidomide (LEN), is an NCCN preferred regimen for transplant-ineligible patients with R/R DLBCL and received accelerated approval in the US (July 2020) and conditional marketing authorization in Europe (August 2021) and other countries, based on data from the L-MIND study. The recommended dose of tafasitamab is 12 mg/kg by intravenous infusion, administered in combination with LEN 25 mg for 12 cycles, followed by tafasitamab monotherapy until disease progression or unacceptable toxicity. Tafasitamab + LEN is associated with durable responses in patients with R/R DLBCL. The majority of clinically significant treatment-associated adverse events are attributable to LEN and can be managed with dose modification and supportive therapy. We provide guidelines for the management of patients with R/R DLBCL treated with tafasitamab and LEN in routine clinical practice, including elderly patients and those with renal and hepatic impairment, and advice regarding patient education as part of a comprehensive patient engagement plan. Our recommendations include LEN administration at a reduced dose if required in patients unable to tolerate the recommended dose. No dose modification is required for tafasitamab in special patient populations.