Urine Color Research Articles

Human Hydration Indices: Spot Urine Sample Reference Values for Urine Concentration Markers in Athletic Populations

Background: Reference values and confidence intervals for the hydration indices of a large athletic population are currently lacking. Methods: Urine indices were gathered from an athletic population (n = 189) based on spot-urine samples. Results: High urine concentration was associated with a low volume and short void duration. When stratifying the data, differences for urine volume were seen for race and ethnicity and for athletic affiliation (p < 0.05), but no differences were found for urine concentration markers or volume for time of day of collection, thirst sensation, or age (p > 0.05). When classifying urine samples for a low vs. a high urine concentration by scoring urine color (Uc), the athletic population reported a slightly lower accuracy (4–7%) compared to investigators (p < 0.02). Subjects scored samples as lighter than the investigators, with a higher misclassification of the more concentrated urine samples. Conclusions: In this convenience sample of a predominantly young athletic population, urinary indices did not differ for subgroups within a large athletic population aside from some difference for race and ethnicity on urine volume. Although well-trained investigators reported better accuracy for Uc scoring, both athletes and investigators reported the highest accuracy for correctly classifying samples with a very low or a very high urine concentration.

Hydration In Athletes: A Literature Review

The aim of this study to review the most recent research on the factors that most influence hydration. This study review using the literature research from google scholar, PubMed, and Elsevier. Many athletes after training experience dehydration due to not consuming enough fluids and electrolytes before, during training, and competition. To assess hydration status cannot be determined by just one factor. The general recommendation of hydration status measures using accurate biomarkers to detect body water fluctuations of 3% of total body water (TBW), using dehydration index, body mass, or color of urine. Therefore, monitoring hydration status is very important to maintain athlete performance. Exercise increases hypohydration due to fluid losses so that should be given to fluid supplementation and intake from certain food for each athlete. The factor that most influences the athlete's hydration is sweat loss and fluid intake.

A Study to Assess the Knowledge on Importance of Hydration during their Working Hours in Terms of Creating Awareness in a Selected Hospital, Bangalore

Background: The knowledge and practice of nurses in terms of water intake during working hours at Apollo Hospitals, BG Road, Bangalore had not yet been studied in depth. Aim: The aim of the research is to assess the knowledge on importance of hydration during working hours pre and post awareness among the nursing staff Design: This study was conducted at Apollo Hospitals, BG Road, Karnataka Region. Information about knowledge and practice of staff nurses towards water intake during working hours were obtained using a well-structured online questionnaire (Google forms). Tools: Online Questionnaire (Google forms) Results: Around 300 nurses took part in the online questionnaire. A majority of the nurses believed that the daily water intake comes from various sources like plain water, beverages, and a mix of foods. Clear colour of urine was the most common indication of proper hydration (86.4%) and 77.8% of the nurses considered tiredness as a common symptom of dehydration. Knowledge about over hydration was very poor among nurses. Conclusion: Implementation of training program about safe practice of fluid intake illustrate a positive effect on nursing staff. Recommendations: Training program should be carried out for nurses related to safe practice of fluid intake as a part of regular nursing education programme. Keywords: Daily water intake, knowledge, dehydration, practice, hydration level, working hours, staff nurses, awareness, hospital

Klasifikasi Dehidrasi Tubuh Manusia Berdasarkan Citra RGB Pada Warna Urine Menggunakan Metode K-Nearest Neighbor

Dehydration is a condition in the body where the amount of fluid that comes out is more than the amount of fluid that enters so that the body experiences a lack of fluids. The simplest way to find out if you are dehydrated is to check the color and amount of urine. If it is very dark and there is little water, then the body needs a lot of air. If the urine is clear, it means the body is in normal air balance. The level of dehydration between each person is different, so we need a system that can classify the level of dehydration objectively through urine, so that it can facilitate the process of early detection and diagnosis before being enforced. Based on the research that has been done, it is found that the Matrix Laboratory (Matlab) can classify dehydration in the human body, by utilizing urine images through several processes, namely preprocessing, segmentation, feature extraction of Red Green Blue and then the K-Nearest Neighbor method to classify a person's level of dehydration. From 30 urine image training data and 15 urine image test data with 3 classes of urine color levels, namely not dehydrated, mild dehydration and severe dehydration, the results obtained from the accuracy of the dehydration level classification using the K-Nearest Neighbor method of 93.3% obtained from 14 test data with accurate classification, and 1 test data with inaccurate classification.

A rare case report of acute acalculous cholecystitis in active chronic hepatitis C virus infection

Acute acalculous cholecystitis (AAC) is an inflammation of gallbladder with absence of gall stones or bile sludge. Daily cases reported about 90-95% of the acute cholecystitis present with gall stone, while only 5-15% occur without gall stones obstruction. AAC is reported associated with Epstein bar virus infection, hepatitis B virus and hepatitis A virus. Hepatitis C-induced AAC cases still rare. This case report presents a 49-years-old female patient with epigastric pain, nausea, yellowish sclera, tea urine color, pale stool and there was a history of the patient's husband with hepatitis C. On physical examination there was epigastric and right hypochondriac pain, and positive murphy sign. There was leukocytosis, hyperbilirubinemia and an increase in SGPT (1.360 U/L) and SGOT (1.720 U/L). Antibodies to HCV were positive. Abdominal ultrasonography showed cholecystitis with no biliary duct dilatation and no parenchymal liver disease appearance The patient was diagnosed with acute chronic hepatitis C and cholecystitis. Pathophysiology of hepatitis C induced AAC is not fully understood, but is thought to be due to complexes immune, directly infect gallbladder and proximal biliary epithelial cells uncontrolled, increased portal/septal myofibroblasts activity and inflammation. The presence of AAC with an increase in serum levels of SGOT and SGPT 5-10 times the normal limit should be suspected due to acute hepatitis viral infection. Further research still needs to be done to determine the relationship between hepatitis C and the incidence of AAC.

Changes in body mass and hydration status in judo athletes before and after a top-level competition: a descriptive case study

ABSTRACT Objectives The International Judo Federation (IJF) implemented new regulations in an attempt to regulate rapid weight loss in 2013. The body weight of the athletes cannot be more than 5% higher than the upper limits of their weight categories at the weight check for randomly selected athletes from each weight category before the competition. However, therea lack of studies demonstrating rapid weight loss and hydration status of elite judo athletes in a real match atmosphere under the current refereeing rules. Thus, this study aimed to examine the body mass and hydration changes of elite judo athletes a week before the competition, official weigh-in, and 24 hours after competition. Methods Eight high-level male judo athletes voluntarily participated in this study. Body mass and urinary measures of hydration status were collected a week before, at the official weigh-in and 24-hour post-weigh-in. Results The one-way repeated-measures ANOVA showed a significant main effect of time on body mass (p < 0.001). Body mass decreased by 5.4 ± 0.7 kg or 6.8% from a week before the competition to official weigh-in (p < 0.001) and increased by 3.0 ± 1.1 kg or 4.2% from official weigh-in to 24-h post-competition (p < 0.001). A significant effect of time was also found in both urine-specific gravity (USG) (p < 0.001) and urine color (UC) among the measurements (p = 0.001). Athletes’ USG values were at the highest level (USG = 1.030 ± 0.001) at the official weigh-in, while they decreased significantly at 24-hour post-competition (USG = 1.017 ± 0.007). Conclusion The results showed that elite judo athletes resort to rapid weight loss and present dehydration despite established regulations by the IJF.

COVID-19 and Stress: A Young Male Presenting with Central Cyanosis, Dark Urine, Oliguria, Jaundice and Anemia due to Methemoglobinemia as a result of Suicidal Naphthalene Mothball Poisoning Recovered with Exchange Transfusion

A young man presented with abdominal pain and vomiting after eating Naphthalene Mothball. He had dyspnea, central cyanosis (SaO2 on air was 67% on air), marked pallor, deep jaundice and dehydration. His urine color was black; and, his plasma in clotted blood sample was brownish. He was treated as methemoglobinemia due to suicidal Naphthalene Mothball poisoning with fluid and electrolyte replacement, ascorbic acid, N-acetylcystine and exchange transfusion twice with four units of whole blood. Dramatic improvement in central cyanosis immediately following exchange transfusion. Psychiatric consultation and counselling were done; he admitted the main reason for committing suicide was socioeconomic stress due to COVID-19.

Etiology and outcome of neonatal cholestasis: an experience in a tertiary center of Bangladesh

BackgroundNeonatal cholestasis (NC) is a major cause of morbidity and mortality in young infants. This study examines the etiology of NC and its outcome during 2 years of follow-up at a tertiary referral center in Bangladesh.ResultsOut of 80 cholestatic infants, 60% had intrahepatic cholestasis with a mean age of onset of 12.4±2.8 days and a mean age of admission of 82.4±29.0 days. The remaining 40% were extrahepatic with a mean age of onset of 6.7±2.3 days and a mean age of admission of 94.6±50.4 days. Biliary atresia (BA), idiopathic neonatal hepatitis (INH), and TORCH (Toxoplasma, rubella, cytomegalovirus, and herpes simplex) infection except rubella were the most common causes. After receiving treatment, 46.2% of the cases improved, 23.8% deteriorated with morbidity, and 30% died. The majority of the children with INH, TORCH, choledochal cyst, hypothyroidism, galactosemia, and urinary tract infection (UTI) with sepsis were improved. Significant mortality was found in BA (56.6%), intrahepatic bile duct paucity (PIBD) (100%), and progressive familial intrahepatic cholestasis (PFIC) (100%) whereas the rest of BA (43.4%) live with persistent morbidity. Significant clinical improvement was observed in 37 (46.2%) cases of cholestasis evidenced by decreasing jaundice, change of color of urine from dark to normal color, change of stool color from pale to yellow, and gradual decrease in liver size from hepatomegaly state. In addition, decreasing median total bilirubin, direct bilirubin, alanine transaminase, gamma-glutamyl transferase, and alkaline phosphatase showed biochemical improvement at 2 years follow-up. The age of admission, etiology, and presence of ascites are the predictors of outcomes.ConclusionBA was the most common cause of extrahepatic while INH and TORCH infection were the most common cause of intrahepatic cholestasis. Majority of children with intrahepatic cholestasis improved but deteriorated with BA and genetic causes. Prompt referral and early diagnosis as well as the etiology of NC were the main determinants of the favorable outcome.

Urine color expressed in CIE L*a*b* colorspace during rapid changes in hydration status.

BackgroundTo investigate how rapid changes in hydration affect urine color expressed in CIE L*a*b* colorspace.MethodsThis study was a two-day crossover design where subjects (N = 30) came in one visit dehydrated, after a 15 h overnight fluid deprivation, and rapidly rehydrated by drinking at least 1000 mL of water in 2 h. On the other visit subjects reported euhydrated and then rapidly dehydrated 2% by walking (3 mph) in a heat chamber (100°F, 50% humidity) for 2 h. Urine samples on both days were collected pre- and post-dehydration/rehydration. Urine osmolality, urine specific gravity, subjective urine color and objective urine color expressed in CIE L*a*b* colorspace were measured.ResultsIn the dehydration trial participants experienced a significant weight loss of approximately 2% of their starting, euhydrated body weight. The CIE urine color L*-value significantly decreased (−2.3 units) while the b*-value significantly increased (16 units). Subjective urine color significantly increased (1 unit). Urine osmolality increased (25 mmol/kg) and urine specific gravity increased (0.002 g/mL) between the pre- and post-dehydration conditions, however, neither of these changes were statistically significant. In the rehydration trial participants had a significant 1.5% increase in body weight after the ingestion of water. Significant increases were observed in the CIE urine color L*-value (7 units) and a*-value (1.1 units), while the b*-value significantly decreased (−24 units). Subjective urine color significantly decreased (−3 units). Urine osmolality (−600 mmol/kg) and urine specific gravity (−0.018 g/mL) significantly decreased between the pre- and post-rehydration conditions.ConclusionsTraditional markers of hydration, including urine osmolality and urine specific gravity, did not significantly change in the acute dehydration trial, suggesting that these values may not be responsive to rapid changes in hydration status. However, the CIE L*- and b*-values of urine color significantly decreased in the rapid dehydration trial and significantly increased in the rapid rehydration trial. Thus, the results of the current study suggest that urine color L*- and b*-values expressed in the CIE L*a*b* colorspace were more responsive to changes in hydration status during rapid dehydration than traditional indices of urine concentration and thus may be better markers under such conditions.

Hydration and Urine Quality in Workers Exposed to Heat Stress (Study on Ceramic Production Workers)

Workers in the ceramic industry were exposed to high heat stress every day, that can caused dehydration. Dehydration can be identified by urine color, urine pH, and urine specific gravity (USG). It is also necessary to know urine quality to indicate the health condition of workers, including by turbidity, presence of protein, epithelium, bacteria, and leucosit. This research is analytic and descriptive, with a cross-sectional. The population and sample are all workers in the ceramic industry center in Klampok Village, Banjarnegara Regency, Central Java, are 55 workers. The variables studied were heat stress, amount of drinking water consumption, dehydration status, and urine quality. Heat stress is measured using a heat stress meter, the amount of drinking water consumption is identified through interviews, dehydration status is measured through urine examination taken after work and analyzed in the Banjarnegara District Health Office laboratory, including color (with standard urine color indicator), pH (with digital pH), and the USG (with a refractometer). The quality of urine is seen from the turbidity, the presence of protein, epithelium, bacteria, and leucocyte levels that analyzed in the laboratory. Based on the urine pH no worker is dehydrated. However, based on the urine colour, 60% of the workers were dehydrated, and based on the USG, 76.4% of the workers were dehydrateded. The relationship between the amount of water consumption based on urine color, p value = 0,013, and based on USG p value= 0,863. 21,8% urine were cloudy, 91% positive protein, 91% positive leucosite, 96,4% normal epithel, 100% positive contains bacteria. There is a relationship between the amount of drinking water consumption with dehidration status based on urine color.

Black Water Fever in Severe Falciparum Malaria: A Case Report

Introduction: Black water fever (BWF) is a complication of severe Plasmodium falciparum infection in hemolysis of erythrocytes into the bloodstream releasing the hemoglobin directly into the blood vessels and causes severe anemia and passage of dark/cola color urine, leading to acute renal failure. Hemoglobinuria or BWF is a rare and severe manifestation of falciparum malaria characterized by sudden intravascular hemolysis followed by fever and presence of abnormal hemoglobin in the urine. Aim: The aim of this study was to diagnose and treat severe malaria infection in a Nigerian patient admitted to the Casualty of the IDH Hospital. Case Presentation: A 20-year-old Nigerian boy came to Kuwait and started complaining abdominal pain, nausea, vomiting and fever two days after his arrival. The investigation revealed high fever (40.8˚C), heart rate 125, blood pressure of 100/60 mmHg. The physical examination was unremarkable, including a normal neurologic examination, no hepatosplenomegaly, rash and neck rigidity. The Giemsa stained thick and thin blood examination confirmed the severe infection of Plasmodium falciparum with 41.0% parasitemia. The patient was admitted to the hospital and started intravenous Quinine (1200 mg loading dose in 5% glucose over 4 hours). The patient was feeling much better on next morning but became unconscious by evening and shifted to ICU. His all CBC parameters were higher and started passing dark/cola color urine. The 12 units of whole blood were exchanged on next morning and became fully conscious on 4th day and his anemia and thrombocytopenia were improved and the color of the urine also became normal. Conclusion: Quinine is used in both complicated and uncomplicated malaria and may cause black water fever in severe infection of P. falciparum. It is caused by the hemolysis of erythrocytes due to malaria and also with the metabolism of quinine, making these cells more vulnerable to hemolysis in falciparum malaria and also in G6PD deficiency.

Know Your Health Signs from the Color of Your Urine

Know Your Health Signs from the Color of Your Urine

Co-relation of Blood in Urine with Likeness of Teaching as Profession

Teaching is a profession that gives rise to all types of professions. Profession means that someone had complete knowledge about a specific field like doctor, engineer, accountant and lawyer. Goal of this study was to link likeness of teaching as profession with presence of blood in urine. Sum of 89 students participated in this study. Urine analysis of all these subjects was performed by urine dipstick test. The existence of red blood cells in urine is known as hematuria and it is of two types. First one is that which shows the symptoms of brown coloration of urine. 11.76% males had blood in urine and 88.24% had no blood in urine while 18.37% females had blood in urine and 81.63% had no blood in urine. 50% males and 14.29% females had blood in urine while 50% males and 85.71% females had no blood in urine. End result of this study was that presence or absence of blood in urine had no co-relation with likeness of teaching as profession.

Fitness level and the relationship between heart rate, body water, dehydration symptoms in adolescents during a pandemic

This study was conducted to find out the body response occurred immediately after bleep test after undergoing a pandemic period of more than one year. This research is an analytic observational study with a cross-sectional approach, using the purposive sampling technique. The research subjects were 43 students, 14 women and 29 men with the criteria (1) sports students who were physically active three times a week during the last 1-2 months; (2) no injury or (3) illness in the last 3-7 days. The instruments used are polar heart rate monitor h-10 (measure heart rate), Omron HBF 375 Karada Scan (assess the percentage of water in the body), and urine color scale (dehydration predictor). Data analysis through homogenity test, Kolmogorov-Smirnov normality test, and Pearson Correlation test. The findings of this research were female (30.2 ± 2.63) and male (36.8 ± 5.31) VO2Max concluded as fair category. There was no significant relationship between heart rate with body water (0.071 &gt; 0.05) and urine color (0.557 &gt; 0.05), even body water and urine colour (0.10 &gt; 0.05). The pandemic period is proven to make fitness levels stand in a fair category. Heart rate, body water percentage, and dehydration do not have a significant relationship with each other.

Fluid Restriction Negatively Influences Perceived Morning Alertness and Visuomotor Ability.

The purpose of this study was to assess the effect of two fluid intake protocols on alertness and reaction time before and after fluid intake. Healthy college-age males (n = 12) followed two fluid intake protocols on separate occasions: (1) prescribed fluid (PF) and fluid restricted (FR). In PF, participants were instructed to consume 500 mL of fluid the night prior to and the morning of data collection. In FR, participants were instructed to refrain from the consumption of fluid for 12 h. To assess hydration status, urine specific gravity and urine color were measured. Participants perceived level of thirst and alertness were also recorded. Participants then completed visuomotor reaction time tests using the Dynavision LED board, using both a central visuomotor test and a peripheral visuomotor test (PVRT) prior to (1) and following (2) the ingestion of 100 mL of water. Participants displayed significantly improved PVRT in PF state as compared to FR (PF1 = 1.13 ± 0.16, PF2 = 1.04 ± 0.14; FR1 = 1.27 ± 0.27, FR2 = 1.18 ± 0.20; p = 0.038, ηp2 = 0.363). Both CVRT and PVRT improved over time, following the ingestion of 100 mL of fluid. Participants in the PF state were also significantly more alert than participants in the FR state (PF = 4 ± 2, FR = 5 ± 2; p = 0.019, ES = 0.839). Collectively, perceived alertness and PVRT were negatively impacted by FR.

Purple Urine Bag Syndrome; Infeksi Saluran Kemih Langka Terkait Penggunaan Kateter Uretra Menetap

Purple Urine Bag Syndrome (PUBS) is a rare phenomenon that is commonly overlooked. PUBS occurs in patients who use indwelling urinary catheters. This condition is characterized by a change in the color of urine including the bag and catheter tube turning purple. The purple color comes from the pigment mixture from the end result of the tryptophan metabolic chain reaction with the help of bacteria that produce sulfatase or phosphatase enzymes in the urine. The occurrence of PUBS requires the interaction of various risk factors simultaneously. PUBS can cause concern for patients, families and medical personnel. Lack of understanding and awareness can lead to misdiagnosis and treatment. For this reason, clinicians and medical personnel must be able to identify PUBS and understand its prevention and treatment. PUBS usually has a good prognosis. Correction of the underlying disease and treatment of symptomatic UTIs can reduce the chances of developing this syndrome.

Dark urine as the initial manifestation of COVID-19: a case report

BackgroundRhabdomyolysis is defined as a syndrome consisting of muscle necrosis and the release of intracellular muscle components into the bloodstream. Although rhabdomyolysis has been previously reported as an initial presentation or late complication of COVID-19, the data on it is still limited, and currently, there is no single case of COVID-19 in the literature that describes creatine kinase levels of more than 30,000 IU/L.Case presentationA 50-year-old African–American male presented to the hospital with decreased urine output, dark urine color, and constipation for the past couple of days. He was found to have acute kidney injury, liver injury, and creatinine kinase of 359,910 IU/L, for which aggressive intravenous fluid therapy was given. Infectious workup resulted in positive severe acute respiratory syndrome coronavirus 2 polymerase chain reaction. Two days after admission, the patient became symptomatic from a coronavirus disease 2019: he developed fever and hypoxia, and was placed on supplemental oxygen and started on a 10-day course of dexamethasone. The patient responded well to the treatment and supportive care for coronavirus disease 2019 and was successfully discharged.ConclusionClinicians should be cognizant of atypical coronavirus disease 2019 presentations. The spectrum of damage of coronavirus disease 2019 is still an evolving topic, and more research is required to reveal the exact mechanisms by which severe acute respiratory syndrome coronavirus 2 leads to rhabdomyolysis.

Factors Affecting Change of the Urine Color as a Hydration Indicator among Critically Ill Patients

Factors Affecting Change of the Urine Color as a Hydration Indicator among Critically Ill Patients

Long-term visual pathway alterations after elemental mercury poisoning: report of a series of 29 cases

BackgroundThere are few clinical data on retinal involvement after acute exposure to high concentrations mercury and the available reports are based on a small number of patients suffering chronic exposure. The purpose of this paper is to report findings in workers acutely exposed to very high concentrations of mercury vapor with the aim of providing data on a possible direct retinal involvement.MethodsTwenty-nine patients and 16 controls were evaluated in a comparative case series. Mercury levels in blood and urine samples, visual acuity (VA), contrast sensitivity (CS), visual field (VF), color discrimination and optical coherence tomography (OCT) were recorded. The pattern reversal visual-evoked potentials (PRVEP), full-field and multifocal electroretinography (ffERG/mfERG), pattern electroretinography (PERG), systemic symptoms, presence of erethism, and electromyography (EMG) were also gathered. A descriptive analysis was performed. The correlations between variables also were studied.In addition, electrophysiological data from those patients with deeper VF defects (group 1) were compared with a normal control group.ResultsTwenty-six workers exhibited symptoms of erethism. The EMG showed sensorimotor polyneuropathy and multiple mononeuropathy. The VA was slightly affected in 48.27% (n = 14) of subjects. Loss of CS in at least one of four spatial frequencies and color vision alterations occurred in 96.5% (n = 28) and 44.8% (n = 13), respectively. VF alterations were identified in 72.4% (n = 21) patients. No morphologic changes were seen in the OCT scans. Latencies over 100 milliseconds and reduced amplitudes of P100 were found in the PRVEP (p < 0.05). The reduced amplitude of the b wave at the ffERG, of the P50 at the PERG and of the P1 wave at the mfERG results (p < 0.05) suggested that the outer retina was involved. Significant negative correlations among blood mercury levels, VA, and ffERG were observed.ConclusionsIn this case series, showed that acute exposure to mercury vapor had a hazardous effect on the visual system. Although neurologic and visual pathway involvement was clearly demonstrated, the differences found compared to control support the existence of a direct functional retinal damage and participation in impaired vision in mercury poisoning.

Dysfunctional Voiding: Does a validated urine color scale correlate with dysfunctional voiding severity score?

Dysfunctional voiding (DV), defined as abnormal coordination between the urinary sphincter and the detrusor muscle in a neurologically intact individual, affects approximately 40% of patients that populate pediatric urology clinics. Improper hydration affects the specific gravity and concentration of urinary irritants, resulting in symptoms similar to those seen in DV patients.