ABSTRACT The preexisting global urban housing affordability crisis worsened during the COVID-19 pandemic. Within nations, households belonging to various socioeconomic strata differentially experienced housing affordability issues, with the low-income households disproportionately bearing the affordability stress compared to the higher-income households. We use a mixed-methods approach to investigate the consequences of COVID-19-induced mortgage stress in 154 low-income homebuyers living in the periphery of the Mumbai Metropolitan Region in India. We draw upon the Conservation of Resources theory to study the stress outcomes due to affordability issues and understand its linkages with household financial wellbeing. A quantitative survey of 154 study participants revealed a significant relationship between mortgage stress and financial well-being mediated by financial stress. Further, qualitative analysis of in-depth interviews of 16 study participants using a comparative lens suggested that the pandemic-induced affordability issues disproportionately affected households with informal employment. Overall, the findings highlight a dynamic nature of affordability and its peculiar interplay with informality, emphasizing the urgency to reorient housing policies toward affordability and informality issues.