This research examines the impact of climate change and urban expansion on urban drainage systems in Hyderabad (Zone-XII, Zone-IV&V), India. It employs a Markov chain-based framework to simulate future climate and land changes. Integrated 1D-2D PCSWMM model is used to assess the hazards posed by these changes. Present and future extreme rainfall event(s) (1-10 days) are simulated to determine maximum flooding hours, valuable for resilience studies. Future rainfall events are simulated under four SSP scenarios using CMIP6 Global Climate Models (GCMs): EC-Earth3-Veg, MPI-ESM-1-2-HR, and MPI-ESM-1-2-LR. The Markov Chain Precipitation Generator (MCPG) model downscales grid-scale precipitation data to station-scale. Future urban land expansion is simulated using the Markov Chain-Cellular Automata (MC-CA) model with Terrset. MCPG model is validated using performance measures, and it showed most increased rainfall events under EC-Earth3-Veg. The MC-CA model obtained a Kappa coefficient of 0.89, indicating an increase in imperviousness in future LULC; 6.1% of vegetation and 29.06% of barren land in 2022 will be urbanized by 2075. A significant increase in extreme flood hazard areas for the 1-day and above 7-day events in the both zones is observed from the PCSWMM results. The study highlighted the importance of Markov chains and event duration in flood hazard assessments.