Urban Cats Research Articles

Epidemiology of fishborne trematodiasis in Kazakhstan

Fish borne trematodes are an important cause of morbidity in Kazakhstan. The number of human cases of opisthorchiidosis (infection with parasites of the family opisthorchiidae) reached a peak of 2521 recorded cases (17 cases per 100,000) in 2002 with a gradual decline to 1225 cases (7.4 cases per 100,000) in 2011. Most human cases are found in the north and north east part of Kazakhstan in areas drained by the Irtysh River and it tributaries. A further focus is found in the north west in the Ural river basin in the European part of Kazakhstan. The most common occupations of patients with opisthorchiidosis included the manual laborers, those employed in the home or unemployed. Necropsy investigations of village dogs in an endemic region revealed 37 of 51 (72%) village dogs infected with either Opisthorchis felineus or Methorchis bilis. Likewise an investigation of 242 cats consisting of strays, village, suburban and city cats revealed 79 (33%) animals infected with O. felineus. Higher prevalences were seen in strays and village cats compared to suburban cats. No urban cats, which lived in apartments, were found to be infected. Other important zoonoses included Echinococcus granulosus, detected in 2 of the 51 necropsied village dogs and E. multilocularis was found in 2 out of 124 necropsied stray cats. Investigations of locally caught fish revealed 10 of 107 (9%) roach (Rutilus rutilus), 49 of 68(72%) ide (Leuciscus idus) and 2 of 79 (2.5%) bream (Abramis brama) infested with trematode metacercariae. No metacercariae were found in 609 crucian carp (Carassius carassius), 35 tench (Tinca tinca), 79 carp (Cyprinus carpio), 46 perch (Perca fluviatilis) or 20 zander (Sander lucioperca).

A door-to-door prevalence study of feline immunodeficiency virus in an Australian suburb.

A door-to-door survey was conducted within the limits of the suburb of Douglas in northern Queensland, Australia, to determine the prevalence of feline immunodeficiency virus (FIV) infection in the overall population of domestic cats. Previous FIV prevalence studies have relied on convenience sampling strategies, leaving out an important group of pet cats that do not receive regular veterinary attention. Saliva was selected for testing because collection was non-invasive and was likely to achieve a high rate of participation. Ninety-six cats were surveyed and tested for salivary antibodies against FIV and with real-time polymerase chain reaction (PCR). PCR was considered to be the gold standard and a cat was considered to be FIV-positive if sequencing results on a PCR product of appropriate size matched previously published FIV genome sequences available in GenBank. Results showed 10/96 cats to be infected with FIV subtype A, indicating a prevalence of 10.4% (95% confidence interval: 4.4-16.4) in the area studied. High risk associations were established with the roaming lifestyle of the cat (P <0.002), presence of abscesses (P <0.03) and occurrence of bite wounds (P <0.10). This is the first known cross-sectional study of a population of urban northern Australian cats living in an affluent suburb and presenting saliva as a potential non-invasive sample for large-scale epidemiological surveys on FIV.

Spatio-temporal variation in predation by urban domestic cats (Felis catus) and the acceptability of possible management actions in the UK.

Urban domestic cat (Felis catus) populations can attain exceedingly high densities and are not limited by natural prey availability. This has generated concerns that they may negatively affect prey populations, leading to calls for management. We enlisted cat-owners to record prey returned home to estimate patterns of predation by free-roaming pets in different localities within the town of Reading, UK and questionnaire surveys were used to quantify attitudes to different possible management strategies. Prey return rates were highly variable: only 20% of cats returned ≥4 dead prey annually. Consequently, approximately 65% of owners received no prey in a given season, but this declined to 22% after eight seasons. The estimated mean predation rate was 18.3 prey cat−1 year−1 but this varied markedly both spatially and temporally: per capita predation rates declined with increasing cat density. Comparisons with estimates of the density of six common bird prey species indicated that cats killed numbers equivalent to adult density on c. 39% of occasions. Population modeling studies suggest that such predation rates could significantly reduce the size of local bird populations for common urban species. Conversely, most urban residents did not consider cat predation to be a significant problem. Collar-mounted anti-predation devices were the only management action acceptable to the majority of urban residents (65%), but were less acceptable to cat-owners because of perceived risks to their pets; only 24% of cats were fitted with such devices. Overall, cat predation did appear to be of sufficient magnitude to affect some prey populations, although further investigation of some key aspects of cat predation is warranted. Management of the predation behavior of urban cat populations in the UK is likely to be challenging and achieving this would require considerable engagement with cat owners.

Costs and Benefits of Trap‐Neuter‐Release and Euthanasia for Removal of Urban Cats in Oahu, Hawaii

Our goal was to determine whether it is more cost-effective to control feral cat abundance with trap-neuter-release programs or trap and euthanize programs. Using STELLA 7, systems modeling software, we modeled changes over 30 years in abundance of cats in a feral colony in response to each management method and the costs and benefits associated with each method . We included costs associated with providing food, veterinary care, and microchips to the colony cats and the cost of euthanasia, wages, and trapping equipment in the model. Due to a lack of data on predation rates and disease transmission by feral cats the only benefits incorporated into the analyses were reduced predation on Wedge-tailed Shearwaters (Puffinus pacificus). When no additional domestic cats were abandoned by owners and the trap and euthanize program removed 30,000 cats in the first year, the colony was extirpated in at least 75% of model simulations within the second year. It took 30 years for trap-neuter-release to extirpate the colony. When the cat population was supplemented with 10% of the initial population size per year, the colony returned to carrying capacity within 6 years and the trap and euthanize program had to be repeated, whereas trap-neuter-release never reduced the number of cats to near zero within the 30-year time frame of the model. The abandonment of domestic cats reduced the cost effectiveness of both trap-neuter-release and trap and euthanize. Trap-neuter-release was approximately twice as expensive to implement as a trap and euthanize program. Results of sensitivity analyses suggested trap-neuter-release programs that employ volunteers are still less cost-effective than trap and euthanize programs that employ paid professionals and that trap-neuter-release was only effective when the total number of colony cats in an area was below 1000. Reducing the rate of abandonment of domestic cats appears to be a more effective solution for reducing the abundance of feral cats.

Coat color mutation frequencies in domestic cat populations of Primorskii krai, Russia

The frequencies of mutant coat color genes have been estimated in the cat populations of five settlements in Primorskii krai, Russia: two cities (Partizansk and Spassk-Dal'nii), a town (Khorol'), and two villages (Dmitrievka and Brovnichi). The genetic profiles of these populations have been found to be relatively homogenous and to correspond of the cat population of the city of Vladivostok studied earlier. No considerable differences in gene frequencies have been found between urban and rural cat populations. The data suggest a common origin of all domestic cat populations of Primorskii krai.

Cats' Night Out by C. Stutson

Stutson, Caroline. Cats’ Night Out. Jon Klassen. Illus. Toronto: Simon &amp; Schuster, 2010. Print. This is an immediately appealing and well designed book – a pleasing convergence of balanced palettes and retro details. Sophisticated and stylish little urban cats cavort throught an overview of twentieth century dance styles against the backdrop of an understatedly cool Gotham night. The minimal text is mindfully integrated into the page design and its counting rhyme cadence comes to an enjoyable visually unstructured, cartoonish climax. When I read Cats’… to myself I was concerned that it shared one short coming with other attractive children’s books. Did the level of textual comprehension required, complexity of the popular culture references and the dark, low contrast palette cohere into a narrative and visual text that is holistically appropriate for a particular children’s age group? It’s discouraging when artful and ambitious books elude toddlers and preschool age audiences while seeming too simplistic to older children to offer sufficient engagement. Such books wash over children leaving them unmoved. Creating a beautiful picture book - which Cats’ Night Out certainly is - is a great accomplishment. Creating a picture book that is beautiful and that is truly directed at and calibrated for children is even more challenging. I knew that Cats’ Night Out would please discerning adults but, what little sartorialist cat-lover and junior aficionado of dance and monochromatic retro architecture would have an affinity for this book? Well, as it turns out, my four year old loves it and goes back through the book to examine all the details and explain which shoes, clothes and colours are the best and ask me baffling questions about “polka dotted Swiss” (I had to look it up – it’s a vintage fabric style). Very well done, indeed. Recommended: 3 out of 4 stars Reviewer: Matilda RocheMatilda spends her days lavishing attention on the University of Alberta’s metadata but children’s illustrated books, literature for young adults and graphic novels also make her heart sing. Her reviews benefit from the critical influence of a four year old daughter and a one year old son – both geniuses. Matilda’s super power is the ability to read comic books aloud.

Hair zinc levels in pet and feral cats (Felis catus)

Zinc is an essential element for maintaining proper functions of animal bodies. It is a component of many hormones and enzymes and a participant in the metabolism of carbohydrates or the synthesis of nucleic acids and proteins. Animal tissues typically contain 10-200 mg of zinc kg–1. Most of this amount (98%) can be found inside the cells. Zinc toxicity is associated mainly with the secondary copper deficit. The aim of the present investigation has been to assess zinc contamination of the environment with coats of domestic and feral cats being the indicator. Urban feral cats are synantrophic animals, living in an urbanized environment and scavenging on human food waste. Thus, they can be treated as a bioindicator of the presence of certain elements in the environment. Analyses of the zinc content in cats’ hair have been performed to check whether the zinc level is connected with cats’ coat colour, living conditions and gender. The coat samples were collected from the middle abdominal region. Then they were degreased and mineralized in a microwave apparatus, in concentrated nitric acid under increased pressure. The zinc content was determined by the ICP-OES method. The mean zinc content in the investigated coat samples was 238.9 mg kg –1 . The lowest zinc content was observed in white hair and the highest – in tortoiseshell hair. The results have confirmed that the content of zinc depends on the hair saturation with melanin. Statistical analysis has shown significant differences between the group of female cats living in the wild (268.09 mg kg–1) and the group of breeding female cats (214.49 mg kg–1) at p=0.05. A higher zinc content was observed in the group of older cats. The mean values did not differ from mean values of the zinc content in the coat and hair of other mammals. Considering the living conditions of the animals, the highest zinc content was noted in the group of animals living in the wild (feral ones).

The cat flea (Ctenocephalides f. felis) is the dominant flea on domestic dogs and cats in Australian veterinary practices

This study was undertaken to determine the flea diversity on urban dogs and cats in Australia in 2009-2010. A total of 2530 fleas were recovered from 291 animals (151 dogs, 69 cats and 71 uncategorised dogs or cats) from veterinary clinics across five states of Australia. The majority of specimens were from coastal areas. The cat flea (Ctenocephalides felis felis) was the most frequent flea species identified (98.8%, 2500/2530). The only other flea species identified was the stickfast flea (Echidnophaga gallinacea) from Western Australia. Sequencing of the cytochrome oxidase subunit II mtDNA revealed a single haplotype across Australia within a subset of C. f. felis (n=19). Our study demonstrated dominance and haplotype homogeneity of C. f. felis on dogs and cats. Although Ctenocephalides canis was recovered from a feral fox, it was not identified from the sample of fleas analysed. This suggests that, under current conditions, it is unlikely that foxes are reservoirs of C. canis for domestic dogs or cats residing in coastal Australia, as previously speculated.

Reduction of feral cat ( Felis catus Linnaeus 1758) colony size following hysterectomy of adult female cats

The size of urban cat colonies is limited only by the availability of food and shelter; therefore, their population growth challenges all known population control programs. To test a new population control method, a free-roaming feral cat colony at the Zoological Park in the city of Rio de Janeiro was studied, beginning in 2001. The novel method consisted of performing a hysterectomy on all captured female cats over 6 months of age. To estimate the size of the colony and compare population from year to year, a method of capture-mark-release-recapture was used. The aim was to capture as many individuals as possible, including cats of all ages and gender to estimate numbers of cats in all population categories. Results indicated that the feral cat population remained constant from 2001 to 2004. From 2004 to 2008, the hysterectomy program and population estimates were performed every other year (2006 and 2008). The population was estimated to be 40 cats in 2004, 26 in 2006, and 17 cats in 2008. Although pathogens tend to infect more individuals as the population grows older and maintains natural behavior, these results show that free-roaming feral cat colonies could have their population controlled by a biannual program that focuses on hysterectomy of sexually active female cats.

The Impact of Anthropogenic Factors on the Behavior, Reproduction, Management and Welfare of Urban, Free-Roaming Cat Populations

ABSTRACTFree-roaming domestic cats constitute an integral part of many urban ecosystems worldwide; their presence results from undisturbed natural reproduction, abandonment by pet owners, and abundant food resources. These cats present controversial and emotional issues regarding management of their high densities, hygiene and epidemiologic risks to humans, and predation of wildlife. Improved urban cat management requires greater knowledge of the anthropogenic factors affecting free-roaming cat populations. In this study, we explored the relationship between caretaker treatment levels and the socio-economics of the caretakers and neighborhoods, and free-roaming cat reproduction management, behavior, and physiology in urban populations. Eight free-roaming cat feeding groups, from eight neighborhoods in Tel Aviv, Israel, were observed for six months. Neighborhoods displayed differences in socio-economic status and housing type, and cat feeding groups reflected different levels of caretaker treatment with regard to neutering, physical interaction with the cats, and medical treatment. We examined whether agonistic behaviors, neutering rates, pregnancy rates, and cortisol levels of the cats differed between groups. We found a strong socio-economic effect on neutering and pregnancy rates: low-income neighborhoods had lower neutering and higher pregnancy rates. Higher-level caretaking was associated with lowered aggression, as well as lower cortisol levels of neutered females. Additionally, analysis of data from 622 registered cat feeding groups from north (high-income) and south (low-income) Tel Aviv, obtained from the municipal veterinary department, revealed a socio-economic influence on reproduction management. Our results indicate that, in urban environments, both the neighborhood's socio-economic status and the caretaker treatment level affect management of these cat populations. We conclude that, to improve cat management success, municipalities should consider addressing these socio-economic differences, while, just as importantly, raising awareness and encouraging caretaker involvement in neutering efforts. Improved caretaker treatment levels can lead to reduced cat aggression, with consequent improved cat welfare and reduced noise disturbance to humans.

Urban cat (Felis catus) movement and predation activity associated with a wetland reserve in New Zealand

Context. House cats are increasingly suggested as having major ecological impacts in semiurban environments. Information on the activity of house cats is relatively scarce, especially in habitats such as wetlands. Aims. This study examines the movement and foraging behaviour of house cats living on the periphery of a wetland reserve in Christchurch city, New Zealand. Methods. Twenty-one domestic cats living in a suburban residential area were studied using radiotelemetry to determine home-range size, mean and maximum distances travelled into the adjacent wetland, and the proportion of time spent in the wetland over a 12-month period. Surveys of prey retrieval for 88 cats were also carried out by cat owners over the same 12-month period. Key results. Cat age and the distance of the cat’s home from the periphery of the wetland were highly correlated with cat movement and hunting activity. These movements were not markedly influenced by season or time of day. Younger cats (&lt;6 years of age) living on the periphery of the wetland had larger home-range sizes, moved significantly further into the wetland and spent a significantly greater proportion of time in the wetland. Cats living close to the wetland also brought a greater diversity and a greater total number of prey items to their home-site. Rates of predation were not significantly influenced by sex or whether the cat was wearing a bell. The most common prey items were introduced rodents and birds; however, 172 of 981 prey items were identified as a native common skink. Conclusions.Consequently, cats living in households on the wetland periphery currently pose a predation risk for the wetland species, and the impact of cats on the native skink population warrants further investigation. Implications. This study suggests that domestic cats will exploit wild habitats but that their potential impact will have both positive (predation of introduced pest species) and negative (occasional direct predation) effects on native wildlife.

Evaluation of euthanasia and trap - neuter - return (TNR) programs in managing free-roaming cat populations

Global estimates of the number of domestic cats (Felis catus) are &gt;400 million. Issues associated with free-roaming cats are of global importance because of animal-welfare and public-health concerns and impacts on native wildlife through predation, competition and disease transmission. In the United States, proposed control solutions for managing urban free-roaming cat populations include euthanasia and trap–neuter–return (TNR) programs. We evaluated control methods using a demographic population model for a 25-year period, with parameters estimated from an unmanaged, free-roaming cat population in Texas. We modelled euthanasia and TNR at 25%, 50% and 75% implementation rates and a 50 : 50 combination of euthanasia and TNR at 25%, 50%, 75% and 100% implementation rates for 0%, 25% and 50% maximum immigration rates. We compared final population size, total number of cats treated and treatment effort relative to population reduction. Population decreases were comparable among euthanasia, TNR and a 50 : 50 combination for all treatment rates when the immigration rate was 0%; however, they were higher for euthanasia at 25% and 50% maximum immigration rates. Euthanasia required higher treatment effort than TNR. Our results indicate that immigration must be prevented and high (&gt;50%) treatment rates implemented to reduce free-roaming cat populations.

Naturally occurring feline leukemia virus subgroup A and B infections in urban domestic cats

A nested-PCR (n-PCR) was used to detect feline leukemia virus (FeLV) proviral DNA in blood samples from 464 sick and 608 healthy domestic cats (Felis catus) selected by convenience, and a significantly high prevalence of FeLV infection was observed. n-PCR results revealed the presence of FeLV proviral DNA in 47.2 % of sick cats and 47.4 % of healthy cats. Phylogenetic analysis revealed that FeLV samples from healthy or sick cats were grouped into separate clades. We determined FeLV subgroups by an n-PCR based on the envelope (env) gene. The partial env gene of FeLV Minas Gerais (MG) samples were compared to various exogenous FeLV isolates and endogenous (enFeLV) provirus from the same region. FeLV-B MG samples were more similar to endogenous sequences and to natural FeLV-B isolates than to either FeLV-A or FeLV-C. The results revealed the circulation of FeLV-B in large populations of urban domestic cats in Brazil.

Revealing cryptic genetic structuring in an urban population of stray cats ( Felis silvestris catus)

Urban stray cat populations have previously been shown to be organized in moderately to strongly genetically differentiated colonies. However, the spatial pattern of this genetic differentiation and the possibility that some cryptic genetic structure occurs have not been investigated. Firstly, we combine a pairwise Fst method, a fully Bayesian clustering method and a multivariate analysis to show that the spatial structure of 17 urban stray cat colonies (Nancy, France) does not match the underlying genetic structure. These colonies are structured in two clusters at the uppermost hierarchical level. Additionally, geographic proximity between colonies does not explain their genetic homogeneity. The spatial pattern in genetic differentiation seems more to be a mixture between low global structure and some highly localized structure, comprising isolated colonies. Variations in the local ecological and social constraints on immigration between colonies may explain this pattern. Secondly, we show that the overall current immigration rate is low (8%). Our results suggest that dispersal does not play a major role in the process of homogenization of allelic frequencies. Our study provides a case-study on the use of Bayesian clustering and assignment methods on a real, small data set with numerous fragmented populations; a population structure that is of high relevance in conservation biology.

Prevalence of Toxoplasma gondii in Stray Cats of Gyeonggi-do, Korea

Toxoplasma gondii is an obligate intracellular zoonotic protozoan with a worldwide distribution. It infects humans as well as a broad spectrum of vertebrate hosts. Cats and wild felidae play crucial roles in the epidemiology of toxoplasmosis. This study was performed to survey the prevalence of T. gondii infection among stray cats in the Gyeonggi-do, Republic of Korea. A total of 174 stray cat blood samples were collected from Gwacheon-si (n=20), Bucheon-si (82), and Yangju-si (72). Positive sera for T. gondii were identified in 14 samples (8.1%) exclusively via the latex agglutination test, 28 (16.1%) via ELISA, and 23 (13.2%) via PCR analysis. The overall infection rate of female stray cats (29.2%) presented as higher than that of male cats (24.0%). This study suggests that T. gondii is widespread in the stray cat population of Gyeonggi-do, Korea. It is urgently needed to control urban stray cat population and to reduce the risk of zoonotic transmission of toxoplasmosis to other animal hosts and humans.

Allergy for cat and sources of the allergens in the urban versus rural areas of Poland

642 Allergy for cat and sources of the allergens in the urban versus rural areas of Poland Liliana Trzpil, and Boleslaw Samolinski. Medical University of Warsaw, Prevention of the Environmental Hazards, Warsaw, Poland. Background: The aim is the comparison of a frequency of positive skin prick test for cat allergen, and the frequency of animal presence at home in various areas of Poland (rural versus urban). The presented data are a part of the earliest outcome of large epidemiological study in the field of allergies which is now run in Poland. Methods: Randomized probe of various polish populations differing in the age range (20Y44 13Y14, 6-7 years old) were included in to the study. Analyzed urban population was gathered in Warsaw (capital of Poland). The second selected region was Zamojszczyzna, being the typical rural area with low industrial density. 3833 respondents completed questionnaires ECRHS II and ISAAC (1596 at urban and 2237 at rural region). 1103 of them were subjected to medical examination directed towards allergy recognition, and had made a skin prick test (474 at the urban and 629 at rural region). Results: 65,5% of persons from urban area revealed the positive skin results (for at least one allergen), while of the rural one the prevalence was significantly lower and equal to 34,5% (p = 0.0001). An frequency of positive cat prick test is significantly higher for urban region when compared to the rural region (18,4% vs. 10.8), and the intensity of the reaction measured as the average diameter of the observed skin prick test bubble is also significantly higher (4,01 vs. 3,63 mm). It was found that a significant difference between urban and rural areas was observed for the cat frequency of presence at home 15% vs. 30%. This data can be also compared with the general frequency of the cat presence in the home and surrounding. For rural areas cat is present in about 59.8% of homes and surroundings, while in urban areas cat is present in 15.4% of homes and surroundings. About 50% of people with positive skin tests for cat have cat at home. In urban area these values are significantly lower and equal to 19.5%. Conclusion: For cat allergies one can observe that frequency of positive skin prick test is higher on the urban region than on the rural region, contrastively to the lower presence of the animal allergy sources. Additionally the frequency of cat presence in homes of sensitive persons is much higher in rural areas than in urban ones. This observation can lead to the conclusion of protective, immunotherapeutic role of the high environmental allergen concentration in rural region.

Feeding-order in an urban feral domestic cat colony: relationship to dominance rank, sex and age

In social species, dominance relationships and access to food resources are often affected by asymmetries in resource-holding potential (RHP) between competitors of different ageesex classes with males usually being dominant and feeding first, followed by females and then juveniles. In this study we investigated how variables such as sex and age affected dominance rank and feeding order in a social group of feral domestic cats, Felis silvestris catus, a sexually dimorphic species in which males are larger than females and do not take part in parental care. Intersexual dominance relationships varied depending on the competitive context: males occupied top rank positions away from food, whereas females increased in rank at the expense of males in a feeding context. Around the age of 4e6 months, kittens were significantly more likely than adults of both sexes to be the first to feed, indicating that they received a certain level of tolerance. These results provide support for game-theory models predicting conflict outcome in favour of the smaller competitor when asymmetries in both the value of winning and in the cost of winning inappropriately may compensate for the smaller competitor’s lower RHP. It is suggested that the results are not an artifact of domestication: unlike male lions, Panthera leo, which usually dominate both females and cubs at kills, male domestic cats may value the food less than females and juveniles, because they do not need to maintain constantly a peak physical condition to defend a group of females and protect offspring from infanticide.

Male Reproductive Success in a Social Group of Urban Feral Cats (Felis catus L.)

AbstractDominance rank, morphological characteristics and reproductive success of adult males were measured in a multi‐male multi‐female group of urban feral cats (Felis catus L.). Paternity of nine litters (34 kittens) of the domestic cat from six females was determined through microsatellites analyses at nine loci. The percentage of multiple paternities in this social group was as high as 78%. A positive correlation was found between male size/body weight and dominance. The males who sired the highest number of kittens were the dominant ones. Additionally, dominant males were more likely to be infected by the feline immunodeficiency virus, a virus transmitted by bites through aggressive interactions. Thus this study demonstrates that rank and body weight were both important in predicting the annual reproductive success. However, it shows that the reproductive benefit associated to rank may be balanced by cost due to at‐risk aggressive behaviour of dominant males.

The Domestic Cat as a Predator of Israeli Wildlife

Predation of wildlife by domestic cats was studied in Israel. Analysis of stomach contents and data provided by observers revealed that many domestic cats enriched the diet provided by their owners with many species of wild animals, including 12 mammals, 26 birds, 18 reptiles, and one amphibian, and scavenged from garbage. The proportion of manufactured cat food and garbage dump food in the diet of urban cats decreased from 70% of stomach volume among those living in rural settlements to 44% among cats living in open areas, with the rest of the stomach contents consisting of wild animals. Of the wild animals hunted by cats, the most common category was mammals (75% of the stomach volume), followed by amphibians (10%), birds (9%), and reptiles (6%). Most cats do not wander more than 200 m away from either a food source or cover. Female cats living in (southern) desert settlements do not leave the inhabited area and have very small home ranges, while those living in the Mediterranean region (central and nor...

Naturally‐occurring chronic renal disease in Australian cats: a prospective study of 184 cases

To describe cases of naturally occurring feline chronic renal disease (CRD) in a defined population of Sydney. Prospective case series. The inclusion criteria were the presence of a serum creatinine concentration above the reference range with either inadequately concentrated urine (urine specific gravity < or = 1.035), necropsy findings consistent with CRD, renal proteinuria or persistent azotaemia despite rehydration. Cats were excluded if a specific aetiology was identified ante or post mortem. Patients were divided into two categories (renal insufficiency or renal failure) on the basis of history, physical findings and serum creatinine concentration. The gender and age of cats with CRD was compared to an estimated Australian urban pet cat population. The breeds of cats with CRD were compared to the breeds of cats visiting the respective veterinary hospital where possible. Breed and gender comparisons were made using Fisher's exact tests. Age comparisons were made using Mann-Whitney U tests. The age at which cats were diagnosed with CRD was compared between veterinary hospitals using a Kruskal-Wallis test. One hundred and eighty-four (99 female; 85 male) cats fulfilled the inclusion criteria. Amongst cats with CRD, males (median 12 years) were significantly younger than females (median 15 years; p = 0.001). The overall proportion of male and female cats with CRD was similar to that of the reference urban cat population (p = 0.41), however, between the ages of 9 and 11 years, male cats with CRD were over-represented (p = 0.038). Patients diagnosed with renal insufficiency (123 cats; median age 15 years) were significantly older than patients diagnosed with renal failure (61 cats; median age 11 years; p = 0.0001). The age at diagnosis of cats with CRD differed significantly between veterinary hospitals (p = 0.002). Male cats with CRD were significantly younger than female cats with CRD. Younger cats were more likely to be diagnosed at an advanced stage of disease than older cats. The age at which cats were diagnosed with CRD was influenced by the clinic the cats attended. Whether these differences reflect differences in the aetiology of CRD or in the rate of disease progression warrants further investigation. Breed did not appear to play a significant role in the development of CRD in this survey.