Results of field experiments conducted during kharif 2016 and 2017 to study the effect of penoxsulam on weeds in transplanted rice are reported. The study comprised 7 treatments consisting of 3 doses of penoxsulam 2.5 per cent OD (20, 22.5 and 25 g ha−1), bispyribac-Na 10 per cent SC (20 g ha−1), pretilachlor 50 per cent EC (750 g ha−1), hand weeding (20 and 40 d after transplanting, DAT) and un-weeded control. Echinochloa crusgalli, Leptochloa chinensis, Caesulia axillaris and Cyperus iria were the major weeds. Application of herbicides reduced weed density and increased grain yield as compared to un-weeded control during both the growing seasons. Penoxsulam at 25 g ha−1 provided effective control of grasses and broad-leaved weeds and sedges with 88.24 and 87.05 per cent weed control efficiency at 45 and 60 DAT. The treatment recorded significantly more panicle length, though the grain yield was at par with penoxsulam @ 22.5 g ha−1 (7.14 and 7.12 t ha−1 and 7.23 and 7.37 t ha−1, during 2016 and 2017 respectively). Penoxsulam at 25 g ha−1 recorded 21.5 and 23.9 per cent increase in grain yield over unweeded control during 2016 and 2017 respectively.