Event Abstract Back to Event CONSOLIDATION THROUGH THE LOOKING-GLASS: SLEEP-DEPENDENT PROACTIVE INTERFERENCE ON PROCEDURAL LEARNING IN CHILDREN Charline Urbain1, 2*, Emeline Houyoux1, Genevieve Albouy3 and Philippe Peigneux1 1 Université Libre de Bruxelles, UR2NF - Neuropsychology and Functional Neuroimaging Research Unit, Université Libre de Bruxelles , Belgium 2 Université Libre de Bruxelles, LCFC - Laboratoire de Cartographie Fonctionnelle du Cerveau, Hôpital Érasme, Belgium 3 University of Montreal, Centre de recherche, Institut Universitaire de Gériatrie de Montréal, Canada Although a beneficial role of post-training sleep for declarative memory has been consistently evidenced in children like in adults, available data suggest that procedural memory consolidation does not benefit from sleep in children. We surmised that despite a possible absence of sleep-dependent changes in performance in children, sleep-dependent plasticity processes involved in procedural memory consolidation might be expressed through differential interference effects on the learning of novel but related procedural material. To do so, thirty-two 10-12 years old children were trained to the rotation adaptation task then retested after either a sleep or a wake period on the same rotation applied at learning, thus assessing offline sleep-dependent changes in performance. We then presented at retest the opposite (unlearned) rotation to assess sleep-dependent modulations in proactive interference of the consolidated visuomotor memory trace against learning of the new rotation. Results show that children gradually improve performance over the learning session, showing effective adaptation to the imposed rotation. Notwithstanding, besides a conspicuous absence of sleep-dependent changes in performance for the learned rotations, the presentation of the opposite, unlearned deviation elicited significantly worse performance (i.e. higher interference effects) after post-training sleep than wakefulness in children. Considering that a definite feature of procedural memory and skill acquisition is the implementation of highly automatized motor behaviour, thus lacking flexibility, our results suggest a better integration and/or automation or motor adaptation skills after post-training sleep, eventually resulting in higher proactive interference effects on untrained material. Consequently, our results suggest that sleep contributes in the consolidation of a procedural adaptation memory in children. Acknowledgements CU is supported by a grant of the ULB-ARC project "Pathophysiology of Memory Consolidation Processes“ and the Fondation Vigneron. GA is supported by a Canadian Institutes of Health Research (CIHR) postdoctoral grant. Keywords: Children, visuomotor adaptation, procedural learning, interference, Sleep, memory consolidation Conference: Belgian Brain Council, Liège, Belgium, 27 Oct - 27 Oct, 2012. Presentation Type: Poster Presentation Topic: Other basic/clinical neurosciences topic Citation: Urbain C, Houyoux E, Albouy G and Peigneux P (2012). CONSOLIDATION THROUGH THE LOOKING-GLASS: SLEEP-DEPENDENT PROACTIVE INTERFERENCE ON PROCEDURAL LEARNING IN CHILDREN. Conference Abstract: Belgian Brain Council. doi: 10.3389/conf.fnhum.2012.210.00019 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 10 Sep 2012; Published Online: 12 Sep 2012. * Correspondence: Dr. Charline Urbain, Université Libre de Bruxelles, UR2NF - Neuropsychology and Functional Neuroimaging Research Unit, Université Libre de Bruxelles, Bruxelles, 1050, Belgium, curbain@ulb.ac.be Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Charline Urbain Emeline Houyoux Genevieve Albouy Philippe Peigneux Google Charline Urbain Emeline Houyoux Genevieve Albouy Philippe Peigneux Google Scholar Charline Urbain Emeline Houyoux Genevieve Albouy Philippe Peigneux PubMed Charline Urbain Emeline Houyoux Genevieve Albouy Philippe Peigneux Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.