Psoriasis, despite its seemingly simple clinic and course, is at the same time a complex socio-economic phenomenon that causes stigmatization of people with this disease. The use of constitutional markers to predict the risk and severity of psoriasis could be a promising way to alleviate this problem. The aim of the study was to establish and analyze the differences in girth body sizes between healthy and/or psoriatic Ukrainian men of different somatotypes depending on the severity of the disease. On the basis of the Military Medical Clinical Center of the Central Region and the Department of Skin and Venereal Diseases with a course of postgraduate education of National Pirogov Memorial Medical University, Vinnytsya, the determination of body sizes’ in men aged 22 to 35 years, suffering from psoriasis of mild (n=32) and severe (n=68) course was carried out. Clinical assessment of the severity and area of psoriatic lesions was performed using the PASI index. Determination of somatotype was performed according to the Heath Carter method. As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya anthropometric data of 82 practically healthy men of the same age group were selected. Statistical processing of the obtained results was performed in the license package "Statistica 5.5" using non-parametric evaluation methods. Compared with healthy men of the corresponding somatotypes, it was found: in patients with mild and severe psoriasis men of mesomorphic somatotype – significantly higher, or a tendency to greater values of almost all girth body sizes (except foot girth, and only in patients with mild course – girth of forearms in the lower part); only in patients with mild psoriasis men of endo-mesomorphic somatotype – significantly higher, or a tendency to higher values of almost all girth body sizes (except for the girth of the foot and lower leg in the lower part). In patients with psoriasis men of endo-mesomorphic somatotype with a mild course of the disease significantly higher, or a tendency to greater values than in patients with a similar course men of mesomorphic somatotype shoulder girth in stressed and unstressed state, forearms, upper and lower arms thighs, hips, shins in the upper part, neck, waist and all the girths of the chest; and in patients with psoriasis men of mesomorphic somatotype with a severe course of the disease – only tendencies to greater values than in patients with a similar course men of endo-mesomorphic somatotype girth of thighs and shin in the upper part. In patients with mild psoriasis men, the differences in body sizes between mesomorphic and endo-mesomorphic somatotypes are similar to healthy men, but are more pronounced. When comparing the girth of the body between psoriasis patients Ukrainian men of the corresponding somatotypes, representatives of the mesomorphic somatotype with severe disease have significantly higher, or a tendency to greater values than with mild course, the girth values of the forearms at the top, neck, waist and all around chest, as well as the tendency to lower values of the girth of the shin. The established pronounced differences in the girth sizes of the body provide an opportunity to identify risk groups for the occurrence and features of psoriasis.