The structural motion and unsteady aerodynamic loads of a pitching airfoil model that features an actuated trailing edge flap are determined experimentally using a single measurement and data processing system. This integrated approach provides an alternative to the coordinated use of multiple measurement systems for simultaneous position and flow field measurements in large-scale fluid–structure interaction experiments. The measurements in this study are performed with a robotic PIV system using Lagrangian particle tracking. Flow field measurements are obtained by seeding the flow with helium-filled soap bubbles, while the structural measurements are performed by tracking fiducial markers on the model surface. The unsteady position and flap deflection of the airfoil model are determined from the marker tracking data by fitting a rigid body model, that accounts for the motion degrees of freedom of the airfoil model, to the measurements. For the determination of the unsteady aerodynamic loads (lift and pitching moment) from the flow field measurements, two different approaches are evaluated, that are both based on unsteady potential flow and thin airfoil theory. These methods facilitate an efficient non-intrusive load determination on unsteady airfoils and produce results that are in good agreement with reference measurements from pressure transducers.