Unsaturated Bile Research Articles

The formation of unsaturated bile acids by intestinal bacteria.

Research Article| October 01 1970 The formation of unsaturated bile acids by intestinal bacteria V C Aries; V C Aries Search for other works by this author on: This Site PubMed Google Scholar M J Hill M J Hill Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1970) 119 (5): 37P–38P. https://doi.org/10.1042/bj1190037P Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation V C Aries, M J Hill; The formation of unsaturated bile acids by intestinal bacteria. Biochem J 1 October 1970; 119 (5): 37P–38P. doi: https://doi.org/10.1042/bj1190037P Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1970 The Biochemical Society1970 Article PDF first page preview Close Modal You do not currently have access to this content.

Hydroboration of B-ring unsaturated bile acids

Hydroboration of B-ring unsaturated bile acids

Dehydration of Bile Acids and their Derivatives. X. A Study of the Physical Properties of Various 3α-Hydroxycholenates and their Derivatives, with Special Reference to their Optical Rotatory Dispersions

Abstract Not only ultraviolet and infrared absorption spectra but also optical rotatory dispersions of various unsaturated bile acids were studied, and most of the data were found to be in good agreement with those hitherto obtained concerning the other steroids. The determination of the rotatory dispersion gave the following results: 1) The background rotation of the saturated bile acid is not affected by the introduction of a double bond in ring B, C or D. 2) The introduction of a double bond in ring C or D does not remarkably affect the RD curve of the saturated 3-keto bile acids, while the negative drift of the RD curve given by 3-keto-Δ6-cholenic acid is so very striking that this phenomenon could be utilized for the diagnosis of Δ6-3-keto bile acids (5β). 3) The positive Cotton-effect RD curve given by a saturated 12-keto bile acid is strongly inverted by the introduction of the Δ8(14)-bond, but not by that of the Δ8-bond.

Dehydration of Bile Acids and their Derivatives. IX. Oxidation of Methyl 3α-Acetoxy-Δ7-cholenate with Selenium Dioxide

Abstract Carefully repeated experiments have shown that, contrary to Fieser’s report3), methyl 3α-acetoxy-Δ7-cholenate and some other un-saturated bile acids (5β) listed in Table I give positive results in the selenium dioxide test. This finding was substantiated by the fact that two oxidation products of methyl 3α-acetoxy-Δ7-cholenate were isolated, one of which was proved to be methyl 3α-acetoxy-7ξ, 15ξ-dihydroxy-Δ8(14)-cholenate. It is very interesting to note that, unlike the Δ7-steroids of the 5α-series, not only C7-H, but C15-H of the unsaturated bile acid mentioned above was oxidized with selenium dioxide to give hydroxyl groups, both of which remained without being acetylated under the experimental conditions described.