Acute toxoplasmosis in three members of the same family was related to drinking unpasteurized goat's milk. The goats were reared, for milk production in a peri-domestic area. Based on indirect immunofluorescent reactions antibody titers greater than 1: 1024 were recorded in eight out of fifteen animals examined and were highest in the five lactating adult females. Toxoplasma was isolated, by inoculation of mice, from the milk of one of these females. Dogs reared in the same house showed no symptoms of acute toxoplasmosis and low antibody titers were detected in these animals. It was also found that the human infections could not have been due to the ingestion of food contaminated with oocysts.