Background. Investigation of synergistic action of atherosclerosis and fatty liver disease is one of the most topical problems of gastroenterology. Aim. Study the characteristics of clinical and laboratory parameters in patients with hepatic steatosis in combination with atherosclerosis of unpaired visceral branches of the abdominal aorta. Materials and methods. The research included 39 patients aged over 50 years with a diagnosis of hepatic steatosis. All patients underwent clinical, laboratory and instrumental studies include certain C-reactive protein, the calculation of indices FIB-4 and Forns, and Doppler ultrasound of the abdominal aorta and its unpaired branches. Results. Patients with atherosclerosis in the pool of the abdominal aorta were significantly older and more likely to suffer coronary heart disease. C-reactive protein in patients with a combination of hepatic steatosis and atherosclerosis visceral branches of the abdominal aorta was significantly higher in comparison with a group of isolated hepatic steatosis (2,66±1,87 and 0,85±0,74 and mg/dl, respectively, p=0.006). Surrogate marker of liver fibrosis FIB-4 index is positively correlated with resistance in the the common hepatic artery (rs=0,717, p=0,03), stage of hypertension (rs=0,624, p=0,017) and the presence of comorbidities among coronary heart disease (rs=0,609, p=0,02). Forns-index is positively correlated with systolic velocity in the superior mesenteric artery (rs=0,574, p=0,032). Conclusion. In patients with hepatic steatosis and atherosclerosis visceral branches of the abdominal aorta detected higher levels of C-reactive protein than in patients without atherosclerosis visceral branches of the abdominal aorta. The positive correlation between the surrogate markers of liver fibrosis (FIB-4, Forns index) and hemodynamics in the upper-mesenteric and common hepatic artery.