Innovations in precision agriculture enhance complex tasks, reduce environmental impact, and increase food production and cost efficiency. One of the main challenges is ensuring rapid information availability for autonomous vehicles and standardizing processes across platforms to maximize interoperability. The lack of drone technology standardisation, communication barriers, high costs, and post-processing requirements sometimes hinder their widespread use in agriculture. This research introduces a standardized data fusion framework for creating real-time spatial variability maps using images from different Unmanned Aerial Vehicles (UAVs) for Site-Specific Crop Management (SSM). Two spatial interpolation methods were used (Inverse Distance Weight, IDW, and Triangulated Irregular Networks, TIN), selected for their computational efficiency and input flexibility. The proposed framework can use different UAV image sources and offers versatility, speed, and efficiency, consuming up to 98 % less time, energy, and computing requirements than standard photogrammetry techniques, providing rapid field information, allowing edge computing incorporation into the UAV data acquisition phase. Experiments conducted in Spain, Serbia, and Finland in 2022 under the H2020 FlexiGroBots project demonstrated a strong correlation between results from this method and those from standard photogrammetry techniques (up to r = 0.93). In addition, the correlation with Sentinel 2 satellite images was as strong as that obtained with photogrammetry-based orthomosaics (up to r = 0.8). The proposed approach could support irrigation leak detection, soil parameter estimation, weed management, and satellite integration for agriculture.