The 28th International Nuclear Physics Conference (INPC2022) was successfully held in Cape Town, South Africa from 11 to 16 September 2022, marking the first time the conference was held on the African continent. This event, overseen by the International Union of Pure and Applied Physics (IUPAP), coincided with three major scientific events: The International Year of Basic Sciences for Sustainable Development (IYBSSD), the centenaries of the Nobel Prize awarded to Niels Bohr and the establishment of IUPAP.The conference program spanned a wide range of topics across the breadth of Nuclear Physics, from hadrons to nuclei, from fundamental science to applications, covering topics such as Hadron Structure and Spectroscopy and QCD Partonic Phenomena, Hot and Dense Nuclear Matter, Nuclear Structure and Nuclear Reactions, Nuclear Astrophysics, Applications and Societal Impact, Neutrinos and Nuclei, Fundamental Interactions and Symmetries, New Facilities and Instrumentation, Outreach and Science Education, and Quantum Computing, Machine Learning, and Artificial Intelligence in Nuclear Physics.The in-person conference was the largest to bring our scientific community together since the COVID-19 pandemic, and provided an excellent opportunity for the 468 delegates to explore the latest progress in the field and reconnect with colleagues. The INPC2022 was a great success, providing an excellent platform for the delegates to share their latest research work, techniques, experiences, challenges, and innovative solutions with colleagues from around the world and provided an opportunity for over 40 African students to be exposed to the field. The conference coincided with the completion of many projects that constitute the pillars of the 2017-2022 Long-Range Plan of iThemba LABS. The delegates had the opportunity to visit the facility and appreciate the advancement and completion of many of these pillars.The INPC2022 was sponsored and supported by the South African National Convention Bureau, Department of Science and Innovation, National Research Foundation, Cape Peninsula University of Technology, University of the Witwatersrand, University of the Western Cape, University of Cape Town, Metrological and Applied Sciences University Research Unit, IUPAP, NuPECC, ACF Metals, XIA and IBA.List of Local Organizing Committee, International Advisory Committee, Session Conveners are available in this pdf.