University Of Toronto Research Articles

“She Is the Seminary”: The Life and Ministry of Dr. Olive L. Clark (1894–1989), Canadian Fundamentalist Educator

This article explores the life and contributions of Dr. Olive L. Clark (1894–1989), a long-time faculty member at the fundamentalist Toronto Baptist Seminary (TBS). In the 1920s, Clark sided with the fundamentalists and became a vocal critic of the Baptist Convention of Ontario and Quebec. As the first person to receive a PhD in Classics from the University of Toronto, she was a gifted scholar. In 1928, she became one of the first faculty members at the newly-minted Toronto Baptist Seminary—operated by the prominent fundamentalist leader T. T. Shields—and remained there until her retirement thirty-eight years later. Through those years and even into retirement, she took an active role in the fundamentalist community by training pastors, publishing lesson plans and articles, speaking in various churches, and serving as co-editor of The Gospel Witness newspaper. In the process, she helped guide and shape the movement, both behind the scenes and in visible ways.

Knowledge Graph Analysis for Chronic Diseases Nursing based on Visualization Technology and Literature Big Data

The use of knowledge graph analysis for chronic disease nursing based on visualization technology and literature big data is an unexplored area of research in this field of study. To uncover research hotspots and developmental trends in the field of chronic disease nursing, and to provide a scholarly reference, we employed mathematical and statistical methods along with CiteSpace literature visualization analysis software for quantitative analysis of extensive literature data from the Web of Science Core Collection. We examined aspects such as publication trends, journals, author collaborations, research institutions, national and regional distributions, keyword co-occurrence, clustering, time zones, emergence, literature co-citations, and more. These analyses identified the current hotspots and future directions for research. Notably, scholars' interest in chronic disease nursing exhibited a consistent upward trajectory. In particular, the field of artificial intelligence technology application in nursing yielded $3,610$ published papers in $141$ journals with more than or equal to $10$ published papers on the topic, accounting for $58.41 \%$ of the total number of published papers in this field of study. Furthermore, the top three publishers were the “Journal of Clinical Nursing,” “Journal of Advanced Nursing,” and “BMC Health Services Research.” Among authors, Hu, Frank B., Willett, Walter C., and Rimm, Eric B., ranked as the top three, and 12 authors had more than 10 publications. The most active research institutions included Harvard University, Harvard Medical School, Brigham & Women’s Hospital, University of California System, University of London, US Department of Veterans Affairs, Veterans Health Administration (VHA), Harvard T. H. Chan School of Public Health, University of Sydney, and the University of Toronto. The United States, Australia, England, China, Canada, Netherlands, Spain, Italy, Sweden, and Germany emerged as the leading countries in terms of research output, while emerging hotspots encompassed topics such as incidence, rheumatoid arthritis, qualitative research, burnout, kidney transplantation, critical illness, COVID-19, Sars-COV-2, public health, and the well-being of medical staff. These findings present valuable insights for prospective research endeavors.

Two for One: Merging Continuing Professional Development and Faculty Development in the CATE Curriculum for Pharmacy Preceptors.

Continuing professional development (CPD) and faculty development (FD) are not traditionally combined, although there is evidence that integrating them enhances knowledge acquisition. To explore preceptors' perceptions and the effectiveness of CATE (Clinical And Teaching Education), an education model that blends clinical content with the application of that clinical knowledge through a specified teaching technique. Thirty-five hospital and community pharmacy preceptors from the Leslie Dan Faculty of Pharmacy, University of Toronto, participated in CATE, which consisted of a 2-hour synchronous, online workshop integrating clinical content about depression with the "One-Minute Preceptor" (OMP) teaching skill. Qualitative and quantitative data were collected longitudinally using surveys and semistructured interviews. Participant and process outcomes were explored through descriptive and thematic analysis using a modified Kirkpatrick framework. Participants valued the incorporation of educational theory and opportunities to practise the OMP using scripted role plays based on the depression-related content. The combination of FD and CPD was appealing, although participants wanted more clarity about their integration. The CATE model positively influenced their approaches to serving as preceptors, and using the OMP helped to reveal learners' knowledge gaps. There was a desire to share the teaching technique with colleagues to provide a more cohesive approach to teaching. Integrating CPD and FD in a synchronous, online environment was feasible and well received, and it helped to solidify preceptors' roles as educators. Combining CPD and FD represents an effective strategy to build the clinical and educational expertise of preceptors, which in turn has the potential to improve the quality of experiential learning for pharmacy students. This novel method of fostering the pedagogical growth of preceptors could be a model for other health professions.

Patient Experience With Resident Versus Staff Physicians: Results From a Cross-Sectional Patient Survey From Canadian Family Medicine Residencies.

We compared experiences of patients who reported usually being seen by a resident with those usually seen by a staff physician. We analyzed responses to a patient experience survey distributed at 13 family medicine teaching practices affiliated with the University of Toronto between May and June 2020. We analyzed responses to seven questions pertaining to timely access, continuity, and patient-centeredness. We compared responses between two types of usual primary care clinicians and calculated odds ratios before and after adjustment for patient characteristics. We analyzed data from 6,545 unique surveys; 18.6% reported their usual clinician was a resident physician. Resident patients were more likely to be older, born outside of Canada, report a high school education or less, and report having difficulty making ends meet. Compared to patients of staff physicians, patients of resident physicians had lower odds of being able to see their preferred primary care clinician and lower odds of getting nonurgent care in a reasonable time. They also had lower odds of reporting patient-centered care, but we found no significant differences in whether the time for an urgent appointment was about right or whether accessing care after hours was easy. In our setting, patients who reported usually seeing resident physicians had worse continuity of care and timeliness for nonurgent care than patients who reported usually seeing staff physicians despite resident patients being older, sicker, and having a lower socioeconomic position. Postgraduate training programs need to test models to support access and continuity for resident patient panels.

Integrating health, nutrition, and environmental impacts of foods: a life cycle impact assessment and modelling analysis of foods in Canada

BackgroundGiven the urgency of transitioning towards sustainable nutrition, dietary shifts that provide co-benefits to human health and the environment are imperative. There is currently no database of the environmental impacts of foods that reflects Canada's unique geographical and agri-climatic context and regional inputs and emissions. To determine sustainable diets, harmonising nutritional considerations with environmental impacts is also essential for an equitable comparison of foods. We aimed to develop a Canadian Food Life Cycle Inventory database and a multidimensional index to enable a joint assessment of the health and environmental impacts of foods in Canada. MethodsThe Canadian Food Life Cycle Inventory database uses life cycle assessment methodology to evaluate environmental impacts. The datasets mirror Canada's food consumption patterns, averaging the spectrum of agricultural practices weighted by domestic production and import shares. The database is structured according to the nomenclature and categorisation of the Canadian Nutrient File. Environmental sustainability is assessed using a cradle-to-grave approach, including indicators such as greenhouse gas emissions, eutrophication, particulate matter, freshwater usage, land use, non-renewable energy consumption, and food loss and waste. Environmental impacts are quantified through an environmental impact score (EIS) assigned to each impact category for a given food. The EIS-nutrition (EIS-N) integrates the evaluation of nutritional quality with environmental impacts using Nutri-Score, a validated food nutrient-profiling tool. The EIS-N is modelled as a ratio of the EIS to the Nutri-Score values. FindingsPreliminary results show the greatest environmental impacts for animal-based foods, particularly beef, in agreement with current literature. Foods with greater nutritional quality also generally show greater environmental sustainability, with some exceptions for particular impact categories. InterpretationThe database and index have potential to serve as powerful tools to support researchers, policy makers, and consumers, harnessing big data to drive efficient food and climate solutions for systems transformation. FundingProvince of Ontario and University of Toronto, CIHR SMART Healthy Cities Training Platform, and University of Toronto's Temerty Faculty of Medicine.

122 Evaluating the impact of the Translational Research Program at the University of Toronto

OBJECTIVES/GOALS: There is a need to develop a workforce of translational research professionals with the skills to innovate, mobilize, and commercialize research for unmet needs in the Canadian health system. The objective of this study is to evaluate the impact and value of the master’s degree on the Translational Research Program (TRP) alumni. METHODS/STUDY POPULATION: This study will use a cross-sectional approach and an electronic survey will be administered to alumni. The TRP was established in 2015 and has graduated over 150 students since its inception. Participants will be recruited through convenience sampling via email, social media platforms, and personal communication. Eligible participants must have a conferred Master of Health Science in Translational Research from the University of Toronto. All collected data will remain anonymous and include demographic information about graduation year, race, ethnicity, gender, and employment status. Descriptive statistics will be used to analyze and report the findings. RESULTS/ANTICIPATED RESULTS: The results of this survey will be used to evaluate how the TRP graduate degree helps alumni contribute to healthcare, learn to think differently, and establish their professional networks. The findings will also be used to inform curriculum improvements, enhance competency-based assessments, and understand demographic differences in student cohorts to promote equity, diversity, and inclusion. Investigating the perspectives of alumni reflecting on their degree will support validating the program’s objectives and advance the integration of translational science principles in the healthcare workforce and community. DISCUSSION/SIGNIFICANCE: This research addresses the need to evaluate health sciences education to ensure the program’s novel pedagogical approaches are equipping the next generation of health professionals with the skills to accelerate the transformation of discoveries into interventions that benefit human health, improve clinical medicine, and enhance patient care.

Comparison of clinical outcomes between single metal-ceramic and zirconia crowns

Statement of problemEvidence comparing the survival of zirconia crowns with metal-ceramic crowns is sparse. Knowledge of their survival and a comparison of their clinical outcomes would improve clinical decision making. PurposeThe purpose of this university-based study was to compare the survival, failures, biological and technical complications encountered with zirconia and metal-ceramic crowns restored and followed up over a similar period. Material and methodsThis retrospective chart review consisted of 403 patients treated at the University of Toronto, Faculty of Dentistry, predoctoral dental clinic in whom zirconia (n=209) and metal-ceramic (n=306) crowns were inserted between September 2015 and July 2016 and followed for up to 7 years. Outcome measures included failure, causes for failure, and complications associated with survival. Inferential statistical analysis included the chi-squared test, t test, Mann-Whitney test, Bonferroni-adjusted z-test, Kaplan-Meier survival test, and logistic regression to examine differences between crown types and explore crown failures (α=.05). ResultsThe mean follow-up period was 3.00 years (median 2.58 years). Forty-one (8.0%) crowns had no follow-up, with no difference in follow-up between crown type: metal-ceramic n=23(7.5%), zirconia n=18(8.6%), χ²(1)=0.20, P=.652). Excluding those with no follow-up, the follow-up time between metal-ceramic (mean=3.07, median=2.58) and zirconia (mean=3.54, median=3.32) crowns was statistically similar (P=.052). There were 62 anterior crowns (12.0%) and 453 posterior crowns (88.0%), χ²(1)=22.40, P<.001, with no difference between groups. Overall, 44 crowns (8.5%) failed, 30 (9.8%) metal-ceramic and 14 (6.7%) zirconia, with no statistical difference in proportion of failed crowns between groups (χ²(1)=1.53, P=.216). There were 35 crowns with biological failures (6.8%), 26 (8.5%) in the metal-ceramic and 9 (4.4%) in the zirconia group, with no statistical difference between groups (χ²(1)=3.33, P=.068). Nine crowns had technical failures (1.7%), 4 (1.4%) in the metal-ceramic group and 5 (2.5%) in the zirconia group, with no statistical difference between groups (χ²(1)=0.73, P=.394). Biological (79.5%) rather than technical complications were found to be the most frequent cause of failure, goodness-of-fit χ²(1)=15.36, P<.001. Tooth fracture (50.0%) specifically was found to be the most frequent cause of failure, χ²(3)=21.27, P<.001. The total number of crowns that survived was 471 (91.5%); 276 (90.1%) were metal-ceramic and 195(93.3%) zirconia. The survival time (years) for metal-ceramic was mean=6.26, 95% CI [6.01–6.51] and for zirconia crowns mean=6.54, 95% CI [6.31–6.77]. Of the crowns that survived, 370 (78.6%) had no clinical complications, and 101 (21.4%) crowns demonstrated similar clinical complications, with no statistical differences between groups. ConclusionsWithin the study follow-up time, the survival of monolithic zirconia and metal-ceramic crowns was 91.5%, with similar clinical complications between groups. Biological complications, especially tooth fracture, were a significantly more frequent complication with both types of crowns.

ECR Spotlight – Sulayman Lyons

ECR Spotlight is a series of interviews with early-career authors from a selection of papers published in Journal of Experimental Biology and aims to promote not only the diversity of early-career researchers (ECRs) working in experimental biology but also the huge variety of animals and physiological systems that are essential for the ‘comparative’ approach. Sulayman Lyons is an author on ‘ Highland deer mice support increased thermogenesis in response to chronic cold hypoxia by shifting uptake of circulating fatty acids from muscles to brown adipose tissue’, published in JEB. Sulayman conducted the research described in this article while a PhD student in Dr Grant McClelland's lab at McMaster University, Hamilton, Canada. He is now a Postdoctoral Fellow in the lab of Dr Jacqueline Beaudry at University of Toronto, Canada, investigating how animals can partition metabolic substrates to fuel metabolism.

Basic Training in Palliative Medicine for Internal Medicine Residents: Pilot Testing of a Canadian Model in Switzerland.

In Switzerland, palliative care (PC) clinical training is well established at undergraduate and specialist postgraduate levels. However, postgraduate nonspecialist training curricula are less documented. A structured curriculum for nonspecialist rotation within internal medicine (IM) in specialized PC wards is lacking. To pilot two versions of a PC nonspecialist curriculum for IM residents in Swiss PC units. In the pilot phase, two curricula-short immersion (3-10 weeks, based on the University of Toronto's Internal-Medicine PC Rotation) and standard nonspecialist (11-18 weeks, based on the Canadian Society of Palliative Care Physician Competencies)-were assessed using a mixed-method online survey. One university and two nonuniversity sites participated. The analysis was descriptive. Five residents and eight supervisors of five training rotations (July-October 2023) responded. Overall, curriculum quality and feasibility (content and time) received positive ratings across all groups, with high satisfaction concerning organization, educational design, learning support, climate, experience, and facilities. Nonuniversity sites were generally rated more positively than university sites. Qualitative feedback paralleled these findings, highlighting the curriculum's relevance and fit with learners' needs and suggesting potential simplifications and more personalized planning. Establishing short and standard duration curricula for a PC program is viable and well received by nonspecialist trainees. Future implementation should concentrate on personalized learning objectives and streamlining the content and structure of the competencies. Cooperation within various training settings (university and regional hospitals) as well as on an international level (e.g., Canada-Switzerland) may further improve the quality of the proposed training formats.

Exploring vocational outcomes, quality of life, and social inclusion in patients with spinal cord injuries following vocational rehabilitation in India

Study designWe conducted a mixed-methods sequential explanatory study. In India, most spinal cord injuries (SCI) occur within low socioeconomic status populations, typically resulting in poor vocational outcomes post-injury and difficulty reintegrating into the community. This study will increase our understanding of how vocational rehabilitation affects patients with SCI.ObjectivesThis study aims to understand the factors affecting vocational outcomes, quality of life and social inclusion for patients who have completed the Amar Seva Sangam (ASSA’s) rehabilitation program, by examining both quantitative and qualitative measures.MethodsConducted at the University of Toronto, we used self-administered questionnaires via REDCap for quantitative data collection and semi-structured interviews for qualitative data collection to capture aspects of lived SCI experience for five participants.ResultsThirty-two participants completed the quantitative phone questionnaire of which 17 were paraplegic and 15 were quadriplegic. Four themes emerged including physical barriers to employment, social inclusion of SCI patients, low income, and state of mental health.ConclusionThis study provided a detailed examination of demographic information and lived experiences of ASSA participants. The findings will be relevant and applicable to both clinical and public health sectors in SCI rehabilitation in India and other low- and middle-income countries by directing rehabilitation programs to better address areas of function that allow patients to find success following rehabilitation.

Macroeconomic Impacts of Immigration in the Canadian Atlantic Region: An Empirical Analysis Using the FOCUS Model

We simulate the impact of an increase in immigration into the Atlantic Provinces based on the FOCUS macro-econometric model at the University of Toronto. That national model was adapted to reflect the regional dimensions of the Atlantic Provinces. We find robust evidence of positive outcomes for the Atlantic region so long as it is part of a broader increase in immigration for the country as a whole. The positive outcome encompasses higher GDP and GDP per capita, higher consumption, and improved government fiscal balances at both the federal and provincial levels that could in turn be used for tax reductions or the enhancement of government services. These benefits could be enhanced further by carefully targeting new immigrants for needed skills and for their likelihood of remaining in the Atlantic region.

Rare Polonica at the Thomas Fisher Rare Book Library, University of Toronto

This article describes a collection of rare Polonica, numbering over five hundred books, pamphlets, manuscripts, and prints and engravings, donated to the Thomas Fisher Rare Book Library in 2001 by Karol Godlewski and his family. The donor’s uncle, Count Emeryk Hutten Czapski (1897–1979), assembled the extraordinary collection. The material includes works written, edited, or translated by Polish authors. The publication dates range from 1505 to the mid-1970s, with two hundred titles predating 1801. The subject matter ranges from texts written by Terence and Plutarch to biographies of Polish kings, details of famous battles, and poetry. There are also etchings of Polish personages, palaces, landscapes, or battle scenes, many of artistic importance.

The Paradox of Parliament Jonathan Malloy, Toronto: University of Toronto, 2023, pp. 304

The Paradox of Parliament Jonathan Malloy, Toronto: University of Toronto, 2023, pp. 304

Exploring the Landscape of Hydrogel Therapy for Spinal Cord Injury: A Bibliometric and Visual Analysis (1991–2023)

BackgroundThis study aimed to conduct a bibliometric analysis of the literature on hydrogel therapy for spinal cord injury to visualize the research status, identify hotspots, and explore the development trends in this field. MethodsWeb of science Core Collection database was searched for relevant studies published between January 1991 and December 2023. Data such as journal title, author information, institutional affiliation, country, citation and keywords were extracted. Bibliometrix, CiteSpace and VOSviewer were used to perform bibliometric analysis of the retrieved data. ResultsA total of 1099 articles pertaining to hydrogel therapy for spinal cord injury were retrieved, revealing an upward trajectory in both annual publication volume and cumulative publication volume. Biomaterials emerged as the journal with the highest number of publications and the most rapid cumulative publication growth, contributing 84 articles. Among authors, Shoichet MS stood out with the highest number of publications and citations, totaling 66 articles. The University of Toronto led in institutional contributions with 65 publications, while China dominated in country-specific publications, accounting for 374 articles.However, to foster significant academic achievements, it is imperative for diverse authors, institutions, and countries to enhance collaboration. Current research in this field concentrates on scaffold architecture, nerve growth factor, the fibrotic microenvironment, and guidance channels. Simultaneously, upcoming research directions prioritize 3D bioprinting, injectable hydrogel, inflammation, and nanoparticles within the realm of hydrogel therapy for spinal cord injuries. ConclusionIn summary, this study provided a comprehensive analysis of the current research status and frontiers of hydrogel therapy for spinal cord injury. The findings provide a foundation for future research and clinical translation efforts of hydrogel therapy in this field.

Analysis of a Bridging Program for Incoming First-Year Students to Transition from Secondary Education to Engineering Education

Bridging programs exist in many institutions to address the challenges incoming students experience. This study aims to identify some of the benefits and challenges of one such program at the Faculty of Applied Science and Engineering at the University of Toronto. Developed during the pandemic, this program aims to reduce the step-in height as students transition from secondary to post-secondary. This exploratory research uses a program evaluation framework to analyze this program. Literature review suggests a systems approach is an effective method, as it dissects the program into its fundamental parts and provides insights to the decision-makers of such programs [1]. We gather anecdotes from entities within the program and pair them with the analysis to identify if this program improves the student experience, and to what degree. This study is not an evaluation of the program, but rather a discussion about bridging programs and factors to consider when designing them. Findings from this study inform developers of bridging programs about their effect on the student experience.

Data Analytics in Engineering Education: Lessons Learned from a Canadian Engineering School

We extended our earlier student data analytics work [1] to further analysis of 10 years of 11,000+ engineering undergraduates’ academic records in the Faculty of Applied Science and Engineering at the University of Toronto to uncover underlying factors impacting students’ academic performance upon graduation. We explored the potential of using supervised and non-supervised machine learning algorithms to select the key features that strongly correlate with the identified students’ academic performance. K-means clustering method was used to study math competency on academic performance and the findings indicate factors other than math can significantly influence student performance. We also applied Association Rule to study life-long learning attributes based on the completion of minors and certificates. From the results, we noticed that technical minors choices correlated strongly with specific core engineering programs and there are also marked differences in terms of gender, legal status and Professional Engineering Year/COOP completion. Various visualization graphical methods including Heatmap, Pie Char, Sanky Diagrams were applied to aid the analysis. The power of data analysis enables a better understanding of our engineering students’ experiences and informs evidence-based decision-making in our school.

LESSONS LEARNED FROM TEACHING SYSTEM THINKING TO ENGINEERING STUDENTS

The primary focus of Engineering Education programs has been to train engineers in various aspects of problem-solving techniques. However, there have been concerns about the types of problems engineering students are exposed to. Most engineering programs train students on solving routine problems, with extension to originative problems in design courses. However, highly complex or “wicked problems” are more rarely explored at the undergraduate level in spite of the fact that they are some of the most important problems faced in society. Systems Thinking has been suggested as a promising approach to addressing wicked problems. We have designed a course in Systems Thinking at the University of Toronto targeted toward students from all disciplines of engineering. The objective of this course is to encourage students to explore the inherent ambiguity of complex problems while introducing them to tools and approaches to visualize their problem space. This paper evaluates the learning experience of students in the first iteration of this course, through a series of analyses performed on their coursework, personal reflections, and interviews. It was hypothesized that teaching Systems Thinking to engineering students would increase their awareness of the problem space, push them to learn about other disciplines outside of engineering, and increase their ability to visualize the elements in the problem. Our results suggest ways in which Systems Thinking has helped engineering students in their problem solving abilities and looks at the specific skills in which engineering students have significantly improved.

Studies of Second-Language Writing in Canada

Canada’s social and educational policies have always involved immigrant settlement and English-French bilingualism. Research on writing in second languages emerged in the 1980s from graduate programs of education and applied linguistics at major universities in Toronto, Montreal, Ottawa, and Vancouver, particularly scholars investigating cognitive and learning processes and rhetorical characteristics of writing in English as a mother tongue. In the 1990s several Canadian scholars established systematic programs of research focused on L2 composing processes, writing for academic purposes, assessment, and innovative educational programs— spawning, in turn, in the 2000s a third generation of L2 writing researchers who have now established themselves across Canada and around the world.

Cultural Distinction and the University of Toronto: Constructing Symbolic Boundaries of Social Class in Canada, 1894–1950

In the first half of the twentieth century, the University of Toronto was a preeminent cultural institution in Canada. Based on a critical interpretation of archival documents, this article narrates the history of four non-formal educational programs through which the University of Toronto created opportunities for Canadians to develop privileged forms of cultural taste and practice: the administration of local examinations in music across Canada, the development of a museum oriented to public visitation, the organization of public lectures in collaboration with local associations across Ontario, and the delivery of non-credit evening courses in Toronto. These four programs engaged hundreds of thousands of Canadians in forms of activity that supported the development of what Bourdieu conceptualized as constellations of cultural distinction: arrays of tastes and practices that mark symbolic boundaries of social class. Two of the programs resulted in national cultural institutions (Royal Conservatory of Music and Royal Ontario Museum) prominent in fields that have been empirically associated with social class boundaries in Canada. The other two programs declined in significance after 1950 and have not previously been included in analyses of cultural distinction. This article explores the historical role of Canadian universities in constructing symbolic boundaries of social class.

The people behind the papers - Andy Yang and Stephane Angers.

Activation of the Wnt signalling pathway is vital in the anterior-posterior patterning during neural development. In a new study, Stephane Angers and colleagues leverage previously developed selective antibodies against Frizzled receptors of the Wnt pathway to stimulate midbrain progenitor differentiation in human pluripotent stem cells. We caught up with first author Andy Yang and corresponding author Stephane Angers, Professor at the University of Toronto, to learn more about the story behind the paper.