Background and Aim: Many factors determine the academic quality of higher education, such as the funding of universities, the quality of teachers, teaching equipment, and so on. Thus, this research aims to investigate the academic guidance ability of university advisors in Guangxi. Materials and Methods: Through using quantitative and qualitative phase ensemble research methods and sampling single factor analysis of variance and t-test, this research investigates the academic guidance ability of university advisors. Results: The results show that given the current situation of university advisors' academic guidance ability, it is proposed to improve the academic guidance ability of university advisors by increasing the intensity of advisor training, improving the academic guidance system of university advisors, doing a good job in the process of university advisor' academic guidance communication, and building an accurate university advisor academic guidance performance evaluation mechanism. Conclusion: According to the literature analysis results of university advisor and academic guidance ability, this study composed university advisor's academic guidance ability by four dimensions: learning motivation guidance ability, learning method guidance ability, learning planning guidance ability, learning process, and evaluation guidance ability.