Vitalism was a scientific theory that prevailed in 18th-century Scotland. Due to the influence of Boerhaave and the teaching of native scholars, vitalism appeared in Scotland in the first half of the 18th century. Its prosperity was closely related to the personal activities of William Cullen and marked by the acceptance and use of vitalism by other new disciplines, especially chemistry. Due to the continuous progress of experiments and the update of experimental instruments, vitalism was gradually replaced by experimental conclusions. Analyzed by social network analysis, the influencing factors affecting the spread of vitalism in Scotland in the 18th century are obtained. Officially, the University of Edinburgh and the teacher-student relationship were the main influencing factors; unofficially, William Cullens influence was the main influencing factor. As a scientific theory, vitalism experienced a limited rise and fall process; as a language of science, vitalism was borrowed by literature and other disciplines and has an influence even in biology today.
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