University Medicine Faculty Research Articles

High-fat and carbohydrate diet caused chronic kidney damage by disrupting kidney function, caspase-3, oxidative stress and inflammation

The study aimed to compare the effects of a diet rich in fat, carbohydrates and protein on rat kidneys. The study was conducted on 40 Wistar albino rats bred at İnönü University Faculty of Medicine after the approval of the ethics committee. Rats were randomly divided into 4 groups: Control group, and the groups where the animals were fed with high carbohydrate, fat and protein rich feed. After the applications, the rat kidney tissues were removed by laparoscopy under anesthesia and blood samples were collected. 13 weeks long fat-rich and carbohydrate feed application had negative effects on oxidant-antioxidant balance, oxidative stress index, inflammation markers, kidney functions tests, histopathology and immunohistochemistry caspase-3 findings in rat kidney tissues, especially in the carbohydrate group when compared to the controls. Protein-rich feed, there were no significant difference in biochemical and histopathology compared to the control group. Fat and carbohydrate rich feed led to an increase in oxidative stress in rat kidney tissues. Oxidative stress led to nephrotoxicity, which in turn led to chronic kidney tissue damages. A more balanced and protein-rich diet instead of excessive sugar and fatty food intake could be suggested to prevent chronic kidney damage.

Implications of obstructive sleep apnea on reproductive health: a study on anti-Mullerian hormone levels.

This study aimed to explore the association between anti-mullerian hormone (AMH) levels and obstructive sleep apnea (OSA) severity. A cross-sectional design was employed to evaluate AMH levels in 68 premenopausal women diagnosed with OSA at Van Yüzüncü Yıl University Faculty of Medicine. OSA severity was scored according to the 2018 AASM guidelines using a 16-channel Embla device. AMH levels were measured from blood samples using a commercially available kit. The study found that AMH levels in OSA patients were significantly lower than those in the healthy control group. A statistically significant negative correlation between AMH and AHI levels was observed. When stratified by OSA severity, the lowest AMH levels were found in the severe OSA group. OSA may have potential endocrine implications, especially concerning reproductive health. Decreased AMH levels in OSA patients could indicate future risks of infertility or early menopause.

Diagnostic value of FDG PET-CT in differentiating lung adenocarcinoma from squamous cell carcinoma

BackgroundLung cancer is the leading cause of cancer-related deaths worldwide. The combination of fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET) and computed tomography (CT) has a major impact on the diagnosis, staging, treatment planning and follow-up of lung cancer patients. The maximum standardized uptake value (SUVmax) is an easily performed and most widely used semi-quantitative index for the analysis of FDG PET images and estimation of metabolic activity. This study aimed to investigate the role of PET/CT in differentiating adenocarcinoma (ADC), the most common lung cancer, from squamous cell carcinoma (SCC) by comparing FDG uptake measured as SUVmax.ResultsBetween 2019 and 2022, 76 patients diagnosed with non-small cell lung cancer (NSCLC) at the Department of Pathology, Atatürk University Faculty of Medicine, with histopathologic evidence of adenocarcinoma or squamous cell carcinoma, underwent retrospective analysis using PET/CT scanning to measure PET parameters of the lesions and compare them with histopathology. Among 76 NSCLC patients included in the study, 43 (57%) were histopathologically diagnosed as ADC and 33 (43%) as SCC. SUVmax, SUVmean, metabolic tumor volume (MTV) and total lesion glycolysis (TLG) values of lesions in patients with SCC were statistically significantly higher than those in patients with ADC (p values 0.007, 0.009, 0.003 and 0.04, respectively).ConclusionsLung SCC has higher metabolic uptake values than ADC, and PET/CT can be used to differentiate them.

There is a lot that health workers can do before an earthquake!

Üsküdar University Faculty of Medicine and Medical Students Association Club held a panel titled "What the February 6 Earthquake Made You Think".

Assessment of hearing sequelae in individuals tested post-trauma.

Over 5% of the global population (430 million people) require rehabilitation for hearing loss. Individuals with hearing impairments face significant challenges in business, daily life, and social participation. Hearing loss (HL) and other permanent physical and sensory disabilities escalate dramatically in cases with brain damage and temporal bone trauma associated with head injuries. This study aims to identify the significant risk factors for hearing loss following head trauma, utilizing current data, and discuss the findings in the context of the literature. This could contribute to the development of standard approaches for assessing such cases. This retrospective study reviewed files and reports from individuals assessed for hearing loss at Dokuz Eylül University Faculty of Medicine, Department of Forensic Medicine. The study included cases that applied at least 12 months post-trauma, between January 1, 2016, and December 31, 2022, after their recovery process was completed. Sociodemographic data, types of temporal bone fractures, initial otoscopic examination findings, presence or absence of intracranial injury, type of hearing loss, and audiometry test results for air and bone conduction pure tone threshold averages were evaluated. Data analysis was conducted using SPSS 26.0 (Statistical Package for the Social Sciences). Out of 244 cases, 177 (72.5%) were male and 67 (27.5%) were female. It was observed that the majority of trauma cases occurred in the 19-40 age group (49.2%; n=120). In the initial otoscopic examinations post-trauma, otorrhagia/otorrhea was the most common finding, both as an isolated symptom (n=59, 24.2%) and when accompanied by other symptoms. No temporal bone fractures were detected in 43 cases (17.6%). Longitudinal fractures were found in 141 cases (57.8%), transverse fractures in 48 (19.7%), and mixed-type fractures in 12 (4.9%). The statistical difference in air conduction and bone conduction pure tone threshold averages between groups with and without intracranial injury was significant (p<0.001). Post-traumatic examinations should employ a multidisciplinary approach, adhering to standard medical improvement and assessment timelines. It is essential to verify whether each patient's medical improvement process has reached its maximum potential. We believe that adhering to these recommendations and utilizing standardized classifications for hearing loss will prevent the loss of rights.

Physicians came together for more qualified medical education and medicine in theory and practice...

The second of the "We Meet Our Physicians" program was hosted by Üsküdar University Faculty of Medicine and NPİSTANBUL Hospital with the aim to further increase the quality of medical education, both theoretically and practically,

Rotavirus Gastroenteriti Olan Hastalarda Elektrolit Dengesizliği ve Kan Gazı Parametrelerinin Değerlendirilmesi

Aim: In the present study, the cases admitted to the hospital because of acute gastroenteritis and diagnosed with common RVGE were evaluated in terms of demographic, epidemiological, clinical, and laboratory data. Methods: The clinical and laboratory data of the cases who applied to Selçuk University Faculty of Medicine, Pediatric Emergency Clinic because of acute gastroenteritis aged 0-18 were evaluated retrospectively in the study. Clinical findings, time of admission, place of observation, blood gas and electrolyte levels, electrolyte imbalance, and length of hospital stays of the patients were recorded. Results: Among the AGE patients who were included in the study, 148 (61.2%) were male and 94 (38.8%) were female. The incidence of hypokalemia in patients who had RV(+) GE was statistically significant. Statistically significant differences were detected between the groups in terms of creatinine, potassium, AST, ALT and albumin values of biochemical parameters. When the blood gas analysis of patients who had AGE was evaluated, although acidosis was detected in 24 (9.9%) patients who had pH value, alkalosis was detected in 27 (11.2%) patients. Conclusion: Cases with metabolic acidosis in rotavirus gastroenteritis are hospitalized more frequently, and for this reason, blood gas studies in cases of RV gastroenteritis will guide clinicians.

The Prevalence of HLA-B*57 Serotype Associated with Hypersensitivity Reactions in the Treatment of HIV İnfection in the Turkish Population.

The aim of our study is to reveal the prevalence of HLA-B*57 in the Turkish population and to provide new perspectives to physicians starting abacavir therapy in HIV patients. Abacavir, one of the drugs used to treat HIV infection, can cause hypersensitivity reactions in some patients. These hypersensitivity reactions have been shown to be associated with the HLA-B*57:01 allele. High-resolution HLA-B*57:01 scanning has a time and cost disadvantage compared with low-resolution HLA-B*57 scanning. Before starting abacavir treatment, we will discuss whether high-resolution scanning is more beneficial in individuals who are positive on HLAB* 57 screening. This is the study with the largest cohort to investigate the prevalence of HLA-B*57 in Turkey. The results of 25 thousand 318 people who applied to Bursa Uludağ University Faculty of Medicine, Department of Immunology for HLA-B* typing were scanned. In our study, the HLA-B*57 serotype was detected in 827 (3.3%) individuals. Considering these results, it can be assumed that the prevalence of HLA-B*57:01 in Turkey is lower than 3.3%. Instead of a high-resolution HLA-B*57:01 scan in all patients starting abacavir therapy, a high-resolution HLA-B*57:01 scan might be of greater benefit in patients who are positive on a low-resolution HLA-B*57 scan.

Relationship of Main Pulmonary Artery (Truncus Pulmonalis) Diameter With Hospital Stay and Mortality in Pulmonary Hypertension Patients Admitted to the Emergency Department.

Pulmonary hypertension (PH) is a haemodynamic and pathophysiological disease significantly associated with morbidity and mortality. The increase in pulmonary vascular resistance, high pulmonary artery pressure and wall tension that occurs in PH results in dilatation of the main pulmonary artery (truncus pulmonalis), one of the largest and most important vessels in the body. The aim of this study is to investigate the relationship between the diameter of the truncus pulmonalis and hospitalization, length of hospital stay, and mortality in patients diagnosed with PH. Demographic characteristics, number of Emergency Department (ED) admissions, post-admission status, treatment, truncus pulmonalis diameter, and mortality were evaluated statistically through the patient files of 115 PH patients who presented to the ED of Fırat University Faculty of Medicine,Elazığ, Türkiye, between January 2022 and December 2022. Of the 115 PH patients who came to the ED, 70 (60.8%) were women and 45 (39.2%) were men, with a mean age of 78.77±8.72 years. Fifty-one of these patients were discharged from the ED after treatment, and 64 were hospitalized. The mean length of hospital stay was two (min=0, max=38) days. Thoracic CT scans demonstrated that the mean diameter of the truncus pulmonalis of the patients was 34.874±3.288 mm (35.20±3.6509 mm in women, 34.367±2.5836 mm in men; p₌0.351) and there was no statistically significant relationship with mortality (p=0.496), hospitalization (p=0.806), and length of hospital stay (p=0.416). There was a statistically significant relationship between mortality rate and male gender (p=0.02) and comorbidity (p=0.001). It was determined that there was no statistically significant relationship between the truncus pulmonalis diameter and gender, comorbidity, hospitalization, length of hospital stay, and mortality in this study in which single-centre one-year admissions of PH, which differ in aetiology, epidemiology, and demographic features were examined. However, among the patient demographics, a significant relationship was determined between gender and the number of comorbidities and mortality.

Evaluation of vitamin D levels and biochemical markers in infants diagnosed with laryngomalacia.

The pathology of laryngomalacia is still not clear. The aim of this study was to investigate the relationship between vitamin D levels and laryngomalacia, and to evaluate vitamin D levels according to the classification of laryngomalacia. This retrospective study was conducted in the Kahramanmaraş Sütçü İmam University Medicine Faculty's Otorhinolaryngology Clinic between June 2014 and January 2021. Laryngomalacia was classified. Laboratory tests for all patients included calcium (Ca), phosphorus (P), parathormone (PTH), blood urea nitrogen (BUN), creatinine (Cre), alanine transaminase (ALT), and 25-hydroxy vitamin D (25-OH-D). Evaluations were performed for 64 infants with laryngomalacia, including 41 male and 23 female infants with a mean age of 4.6 ± 3.0 months, and a control group of 64 healthy infants with a mean age of 4.5 ± 2.8 months. A statistically significant difference was determined between the laryngomalacia group and the control group with respect to 25-OH-D and PTH levels (p < 0.001). When data were examined according to laryngomalacia types, a statistically significant difference was determined between the groups for 25-OH-D, Ca, P, PTH, and ALT values. The 25-OH-D level was statistically significantly lower in the severe laryngomalacia group than in the mild and control groups (p < 0.001). A statistically significant difference was determined between the moderate and severe laryngomalacia groups and the control group regarding PTH levels (p < 0.001). Vitamin D deficiency may have a role in the etiology of laryngomalacia, and this view is supported by the finding that there was a decrease in vitamin D levels associated with laryngomalacia classification. In addition, the reduction in PTH levels in infants with laryngomalacia may be explained by the change in Ca metabolism. It would be appropriate for further studies to investigate the response to vitamin D replacement therapy in patients with moderate and severe laryngomalacia.

Evaluation Of The Relationship Of Kinesiophobia With Anxiety, Upper Extremity Disability And Quality Of Life In Patients With Frozen Shoulders

Abstract Introduction Frozen shoulder is a painful shoulder disease in which glenohumeral joint movements are actively and passively restricted in all directions. If not treated, it can cause various psychological diseases and muscle and joint diseases. Kinesiophobia; this is defined as a fear of physical activity resulting from excessive sensitivity and an uncomfortable feeling due to painful or repeated injury. In this study, it was aimed to evaluate the relationship of kinesiophobia to upper extremity disability, anxiety and quality of life in patients with frozen shoulder. Materials and methods Fırat University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, between September 2020 and March 2021; As a result of clinical evaluation and radiological examinations, patients were enrolled between the ages of 18–75 and who agreed to participate in the study; 48 patients were diagnosed with frozen shoulder and met the inclusion and exclusion criteria of the study and were included in the patient group; Fourty healthy subjects aged between 18–75 years, who did not have shoulder disease and who met the inclusion and exclusion criteria of the study, were included in the control group. A total of 88 cases were included in the study. The following scales were used. TAMPA kinesiophobia scale to assess kinesiophobia in patients and control group, Beck Anxiety scale to assess anxiety in patient group; The Disabilities of The Arm, Shoulder and Hand (DASH) scale to assess upper extremity disability; Short Form (SF)-36 was used to assess quality of life. Results TAMPA kinesiophobia scale was found to be significantly different in the patient group when the patient group and control group were compared. According to the correlation analysis, the TAMPA kinesiophobia scale showed a positive correlation with the Beck-Anxiety and DASH scales in the patient group, while a negative correlation was found with the SF36-Physical function, emotional role difficulty and social functionality. Conclusion In patients with frozen shoulder, kinesiophobia seems to be associated with increased anxiety and upper extremity disability, as well as low quality of life. Structural disorders as well as psychological factors should be taken into account among the reasons for the prolonged limitation of movement and delayed recovery. When the physicians serving in the primary care are experienced with patient management with frozen shoulder, as evaluated for therapeutic purposes, planning psychological support treatments in addition to medical and physical therapy will increase the quality of health care provided to patients.

Peer education model in Trakya university faculty of medicine

BackgroundPeer education is an education model applied to change knowledge, behavior, and attitude in groups equal to each other regarding age, education, and status. This model is preferred in universities to improve teaching skills and reduce the stress level of students. This study aims to apply the peer education model at Trakya University Faculty of Medicine to receive feedback from students and to examine its effect on exam results.MethodsThis cross-sectional, descriptive, and analytical study was conducted with second-year medical students in parasitology laboratory lessons. Eighteen out of a total of 264 students were selected as peer educators. Peer educators have reached the level of providing education to students by taking the training before the laboratory lessons. At the end of the study, questionnaires were applied to peer educators and students. The students’ of 2021–2022 exam results were compared with the 2018–2019 academic year results.ResultsA total of 233 students were surveyed, and 78.5% (183/233) of them believe peer education is helpful, 69.9% (163/233) think it can help them reinforce what they have learned in theoretical lessons, 54.5% (127/233) think it should be used in other practical lessons, and 64.3% think it should be used in the coming years. While there was no significant difference between the exam results of the students in 2021–2022 and the 2018–2019 period (p: 0.462), a significant difference was found between the exam results of peer educators and students (p < 0.05).ConclusionsIt is known that with the peer education model, student stress will decrease, and interest and participation in the lesson will increase. Continuing this education model in the coming years and expanding it to other laboratory courses will benefit medical education.

Associations between neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and prognosis in patients with neuroblastoma.

Recent studies have shown that the neutrophil-to-lymphocyte ratio (NLR) is a new inflammatory marker that is effective in determining the prognosis of many solid tumors, chemotherapy responses, survival, and their recurrence rate. Therefore, we performed a retrospective study to investigate the effect of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio (PLR) on risk factors and prognosis in these patients. In this study, 246 pediatric patients with neuroblastoma who were diagnosed, treated, and followed up during 2000-2021 in Division of Pediatric Oncology, Çukurova University Faculty of Medicine, were included. Required information of patients was obtained from archive files, Mergentech hospital program, and E-pulse system. Median value for NLR was found to be 1.06, for PLR it was found as 92. The relationship of NLR values with age, stage, risk group, and Shimada was found to be statistically signifıcant with p<.001, vanillylmandelic acid (VMA) (p=.006) also depicted the signifıcant value. Likewise, the relationship of PLR values with age (p<.001), stage (p=.022), Shimada (p=.004), and N-Myc amplification (p=.039) was found to be statistically significant as well. Survival analysis showed that no statistically significant difference was observed among the higher and lower values of NLR. Survival rates were noticed to be higher in the lower values of NLR (10-year overall survival [OS] 55% vs. 49%, 10-year event-free survival (EFS) 54% vs. 43%), albeit nonsignificant. Pretreatment evaluation of NLR and PLR values in patients with neuroblastoma may be instructive in respect of prognosis and risk group.

KNOWLEDGE LEVELS, ATTITUDES, AND BEHAVIORS OF PREGNANTS ABOUT PRENATAL SCREENING TESTS: A SECTIONAL STUDY

Aim: To determine the knowledge levels, attitudes, and behaviors of pregnant women who come to the obstetrics clinic in a university hospital about prenatal screening tests.&#x0D; Method: It is a descriptive cross-sectional study. The population consists of approximately 900 pregnant women who are 28 weeks and beyond, who applied to …….. University Faculty of Medicine, Obstetrics and Gynecology outpatient clinic between October-December 2021. The research questionnaire was applied face to face to those who agreed to participate in the study. The data form consisting of 21 questions included questions about the descriptive characteristics and obstetric histories of pregnant women.&#x0D; Results: 254 people participated. The mean gestational week of the participants was 34.9±3.9 (min:28-max:41). The most common screening tests were detailed ultrasound (80.7%) and double screening tests. Those who received information from their obstetrician had a significantly higher rate of having the test. When the participants' knowledge scores about prenatal screening tests are evaluated, respectively; Detailed ultrasound knowledge score was 5.6±0.9, Double test 5.0±1.3, Oral Glucose Tolerance Test 4.8±1.1, and Triple test 4.7±1.2(min:2-max:7). When the reasons for not having prenatal screening tests were questioned, the most common answer for all screening tests was "I don't think the test is necessary". For the OGTT, the second most common reason for not having it done was because they heard from the media that the test was harmful. The fact that the pregnant women had a double and triple screening, went to regular controls and had a high double-triple test knowledge score had a significant effect. Amniocentesis was recommended for 3.5% of the pregnant women based on prenatal test results, but none of them had amniocentesis. In case of unfavorable prenatal test results, the majority of pregnant women were considering continuing the pregnancy.&#x0D; Conclusion: In this study, we found that the rate of testing increased with the increasing knowledge level of pregnant women and physician counseling. In this context, health professionals should provide women with the necessary education about screening and diagnostic tests to enable them to make informed decisions.

Feasibility of totally extraperitoneal inguinal hernia repair in patients with previous prostatectomy.

Laparoscopic totally extraperitoneal inguinal hernia repair (TEP) surgery technique includes three key steps: reaching the preperitoneal space, reducing hernias, and placement of mesh. However, reaching the preperitoneal space can be complicated in patients with previous lower abdominal surgeries. This study aimed to assess the feasibility of laparoscopic inguinal TEP in patients with previous prostatectomies. Inguinal hernia patients who underwent laparoscopic TEP between January 2015 and February 2021 at Koç University Faculty of Medicine, Department of General Surgery, were included in this retrospective study. The operations were performed by five senior surgeons experienced in laparoscopy. Patients were divided into two study groups, as the radical prostatectomy (RP) group which included patients with previous prostatectomy non-RP which included patients without previous radical prostatectomy. Operative time (OT), length of hospital stay (LOS), and postoperative complications were compared within two groups. Three hundred and forty-nine patients underwent laparoscopic TEP, and 27 had previous prostatectomies. Among them, 190 patients had unilateral inguinal hernias, and 159 had bilateral inguinal hernias. Mean age of the patients in the non-RP and RP groups was 58.1 ± 14.7 and 73.9 ± 9.6 years, respectively. Only one (3.7%) case was complicated with urinary tract infection in the RP group, and 10 (3.1%) were complicated in the non-RP group. Complications for the non-RP group include hematomas in six cases, urinary tract infection in three cases, and urinary retention in one case. No significant difference in mean operative time was seen between non-RP and RP groups (p= 0.43). There was no significant difference in the means of the length of hospital stay between the two groups (p= 0.7). Laparoscopic TEP in patients with a previous prostatectomy can be performed safely without prolonging the operative time and increasing the length of hospital stay.

Op. Dr. İlhami Güneral (1914–2006), author and illustrator of the first original dissection manual in Turkish and his contributions to anatomy

Objectives: İlhami Güneral was a Turkish physician and surgeon whose contributions to anatomy education and medical illustration remained under-appreciated until this day. This study aims to outline his achievements throughout his career and acknowledge his unreported contributions to anatomical sciences in Türkiye. Methods: A series of interviews were conducted with his surviving family, relatives, and friends. Additional documents were also collected from various national and international institutions. Results: İlhami Güneral was born in 1914 in Anadolu Kavağı, İstanbul. He attended İstanbul University Faculty of Medicine and graduated in 1942. Upon graduation, he published his first book titled “Diseksiyon Atlası” which he also illustrated himself. His illustrations were later used in Prof. Dr. Zeki Zeren’s dissection handbook published in 1953. He visited and worked with renowned neuropathologist Philipp Schwartz between 1958 and 1960 in Warren, Pennsylvania. During his stay, he co-constructed a detachable “Transparent Brain Model” for teaching brain anatomy which was awarded with the Billings Gold Medal at the 109th Annual Meeting of the American Medical Association. After his return to Türkiye, he published his final illustrated anatomy atlas in 1972, the “Atlas Cerebri Humani”. He spent the remaining days of his life in his long standing home in Ödemiş, İzmir, as a private physician and surgeon. He was diagnosed with prostate cancer in 1993, and passed away due to his illness in 2006. Conclusion: This interesting and unique dramatis persona is the author and illustrator of the first original dissection manual printed in Turkish.

Is laparoscopic surgery safe and feasible in acute adhesive ileus?

Although the classical surgical treatment of adhesive ileus is performed using the open method, laparoscopic surgery has recently been performed in some centers. This study aimed to discuss the feasibility and role of laparoscopic surgery in the treatment of adhesive small bowel obstruction. In this retrospective study, the data of 830 patients who were operated for ileus in Başkent University Faculty of Medicine, Ankara Hospital, Department of General Surgery between January 2011 and September 2022 were analyzed. Missing data and intraabdominal cancer-related ileus were accepted as exclusion criteria and 648 patients were excluded from the study. The development of adhesion-related ileus and completeness of the data were accepted as inclusion criteria. Data were compared between the 2 groups [open group (OG; 152 cases) and laparoscopic group (LG; 30 cases]). When the patient characteristics were evaluated, it was found that the history of previous abdominal surgery (P < .001) and the number of previous abdominal surgery (P < .001) were statistically significantly higher in OG. Operation time was significantly longer in the LG (P = .022). There were no statistically significant differences between the groups in terms of intraoperative bowel injury (P = .216), bowel resection (P = .284), and stoma creation (P = .331). OG had a significantly higher rate of Clavien-Dindo grade ≥ 3 serious complications (P < .001) and mortality rate (P = .045). The first gas out occurred significantly earlier in the LG (P = .014). Oral intake was initiated earlier in the LG (P = .004). The length of hospital stay was significantly shorter in the LG (P < .001). There was no significant difference between the groups in terms of postoperative ileus, readmission, and reoperation. Laparoscopic surgery can be safely performed for the treatment of selected patients with adhesive small bowel obstruction. In addition, it is advantageous in terms of postoperative recovery.

Prognoses of Multicystic Dysplastic Kidney Patients: A Single Center Experience

Introduction: In this study, was aimed to evaluate the demographic characteristics and follow-up results of patients with multicystic dysplastic kidney (MCDK) in our pediatric nephrology clinic, in the light of the literature.&#x0D; Material and Methods: The files of the patients who applied to the Pediatric Nephrology Clinic of Selçuk University Faculty of Medicine between January 2011 and January 2022 were analyzed retrospectively. Data of 22 patients with MCDK were recorded.&#x0D; Results: Twelve (55%) of the patients were left-sided and 10 (45%) were right-sided MCDK. Urinary system infection (UTI) was seen in three patients. Right-sided MCDK was accompanied by right ureterocele in one patient and hydronephrosis in the contralateral kidney in 5 patients. No urinary anomaly was observed in other patients. Proteinuria and hypertension were not detected in the patients. Vesicoureteral reflux (VUR) was not detected in 5 patients who underwent voiding cystourography. In the follow-up of the patients, MCDK was involved in a mean of 16.2±29.3 (1-107) months.&#x0D; Conclusion: Multicystic dysplastic kidney in children has a good prognosis with conservative management. Periodic follow-up is important to prevent the potential development of hypertension or hyperfiltration injury.

Transformation of Conventional Archives into Digital at the Medical Faculty of the University X

Archiving is one of the office jobs that is experiencing digital transformation. Digital archives make it easy for employees to complete their work however, it does not rule out that digital archives have weaknesses that can reduce employee performance. The purpose of this study was to analyze the digital filing system used by the X University Faculty of Medicine, find out whether the system used was effective or not, and find out the weaknesses of the digital archiving system. The research method used in this research is descriptive qualitative with a case study approach. The results of this study indicate that digital archives help employees complete work more quickly and make it easier for employees to carry out administrative activities in agencies. However, behind that it is necessary to repair, improve and upgrade the system so that problems do not occur and can be used more optimally.

Factors affecting academic achievement of third-year students of Bursa Uludağ University Faculty of Medicine

The present study aimed to investigate the determinants of academic performance among third-year students in the Faculty of Medicine. A survey consisting of 45 questions was administered to 357 third-year students in the academic year 2017-2018, with a response rate of 233 participants. The academic achievement was assessed by evaluating the grade point average (GPA) scores, with a threshold of 3. The results revealed that several factors were significantly associated with a GPA score of 3 and above, including age (p=0.011), relationship with parents and positive parental attitude (p=0.001), staying with family (p=0.015), and school selection to “be a doctor” (p=0.044). The results also showed that negative parenting behaviors and smoking were associated with an increased risk of academic failure. However, no significant association was found between academic performance and gender, physical exercise, parents’ education, and employment status. This study highlights the crucial factors impacting academic achievement in medical education. The results demonstrate the importance of age, relationship with parents, parental attitude, reasons for choosing a medical school, smoking habits, and extracurricular activities in determining GPA outcomes. The findings have important implications for the future planning of students, the development of education, and the formulation of new policies