Urgent problems of modernity necessitate the humanization and democratization of all spheres of public life. In these conditions, the social significance of the medical profession is growing. Particular attention is paid to the professional and ethical culture of the medical worker, because ignoring the universal values and professional norms leads to the deterioration of the patient's health. The need to study the problem of developing professionally significant qualities of future doctors in the process of professional training is caused by the requirements for medical workers, as they have a great responsibility for human health and life. The profession of a doctor makes high demands on his personality, concerning not only the quality of professional training, but also a number of personal characteristics. That is why the priority direction of improving the professional training of medical students is the formation of their professionally significant qualities. Based on the analysis of scientific sources, various approaches to determining the essence of professionally significant qualities of medical students are analyzed, their content is detailed, and prospects for further research are determined. The positive intellectual qualities included flexibility of thinking, competence, observation, professionalism, erudition, curiosity, and the negative ignorance (lack or limitation of basic knowledge required to meet the standards of professional activity), mediocrity (intellectual limitations in the field of professional knowledge, satisfaction minimum level of knowledge and experience, lack of desire for self-education); inattention (difficulty in perceiving and fixing attention on professionally significant facts, which leads to confusion and errors in professional activitiesIt is investigated that for effective professional activity the set of professionally important qualities of a medical student in the most general form can be represented as follows: moral and ethical (honesty, decency, responsibility, intelligence, humanity, kindness, reliability, principledness, selflessness, ability to keep one's word) ; communicative (personal attractiveness, politeness, respect for others, willingness to help, authority, tact, attentiveness, observation, sociability, trust in others); strong-willed (self-confidence, endurance, restraint, balance, determination, initiative, independence, purposefulness; organizational (demanding of oneself and others, tendency to take responsibility, ability to make decisions, properly evaluate oneself and the patient, ability to plan one's professional activity) .