Unique Quantification Research Articles

Subhalos in Galaxy Clusters: Coherent Accretion and Internal Orbits

Subhalo dynamics in galaxy cluster host halos govern the observed distribution and properties of cluster member galaxies. We use the IllustrisTNG simulation to investigate the accretion and orbits of subhalos found in cluster-size halos. We find that the median change in the major axis direction of cluster-size host halos is approximately 80° between a ∼ 0.1 and the present day. We identify coherent regions in the angular distribution of subhalo accretion, and ∼68% of accreted subhalos enter their host halo through ∼38% of the surface area at the virial radius. The majority of galaxy clusters in the sample have ∼2 such coherent regions. We further measure angular orbits of subhalos with respect to the host major axis and use a clustering algorithm to identify distinct orbit modes with varying oscillation timescales. The orbit modes correlate with subhalo accretion conditions. Subhalos in orbit modes with shorter oscillations tend to have lower peak masses and accretion directions somewhat more aligned with the major axis. One orbit mode, exhibiting the least oscillatory behavior, largely consists of subhalos that accrete near the plane perpendicular to the host halo major axis. Our findings are consistent with expectations from inflow from major filament structures and internal dynamical friction: most subhalos accrete through coherent regions, and more massive subhalos experience fewer orbits after accretion. Our work offers a unique quantification of subhalo dynamics that can be connected to how the intracluster medium strips and quenches cluster galaxies.

Penerapan Pijat Akupresur pada Ibu Hamil Trimester I untuk Mengatasi Masalah Emesis Gravidarum di Wilayah Kerja Puskesmas Putri Ayu Kota Jambi

Nausea and vomiting or emesis gravidarum are the most common discomforts in the first trimester of pregnancy. If nausea and vomiting are not treated immediately, the body will become weak, dehydrated and have a pale face. Based on the results of the study, Mrs. D, 32 years old, first trimester of pregnancy with the main complaint of nausea and vomiting. One way to reduce nausea and vomiting is with acupressure massage techniques. Acupressure massage is done by gently pressing the PC 6 point for 2 minutes, the aim of which is to have an effect on giving acupressure massage to pregnant women in the first trimester to overcome the problem of emesis gravidarum. The method used is a case study with data collection techniques through observation, interviews and physical examination with the superior intervention of acupressure massage to reduce emesis gravidarum or nausea and vomiting. The results showed that there was a diagnosis of nausea with the intervention of giving acupressure massage for 3 days. The results showed that after the acupressure massage there was a decrease in the Pregnancy Unique Quantification of Emesis and/or Nausea (PUQE) score on the first day of the intervention with a score of 8 (moderate nausea and vomiting category) after the day all three interventions with a score of 3 (mild nausea and vomiting category). Conclusion: Application of acupressure massage can reduce emesis gravidarum or nausea and vomiting in first trimester pregnant women.

Validation of Sinhala and Tamil translations of the motherisk: Pregnancy unique quantification of emesis (PUQE) scoring system

Aims: Nausea and vomiting in pregnancy (NVP), where there are no other underlying causes, is one of the most common symptoms in the early part of the pregnancy. It is responsible for up to 80% of pregnant population. By using PUQE score system, it is very convenient to categorize pregnant women with nausea and vomiting come to outpatient department (OPD) or general practice into those who can manage in community setting or those who need inpatient treatments. Objectives: Validation of PUQE instrument to assess NVP and hyperemesis gravidarum (HG) women in Sri Lanka. Methods: Descriptive cross-sectional study conducted among 160 pregnant women presented to the Gynecology Unit of Teaching Hospital Anuradhapura (ATH) during three months duration. Translated self-administered PUQE questionnaire was applied to the patients with signs and symptoms with emesis in pregnancy. All study participants were undergoing clinical judgment as a confirmation test. Diagnostic test accuracy methods were used to assess criterion validity of the experimental tool. Data were analyzed by using SPSS statistical software version 25.0. Results: Study population has a mean age of 27.96 (SD 5.31). Majority of study participants were Sinhalese and according to the parity majority were primigravida pregnancies. Majority of study participants were diagnosed as NVP Stage II (N=134:53.8%) by the PUQE scoring system. According to the clinical judgment Stage II of NVP was diagnosed among 127 (79.4%) study participants. Mean score of the PUQE scale was 9.08 (SD=2.35). Reliability assessment of the PUQE scoring system was reported as an excellent level (Cronbach alpha=0.804). Five types of management strategies were detected among study participants. Significantly high percentage of study participants were given first line antiemetics and oral rehydration solutions. Calculated sensitivity of the PUQE scoring system to diagnose Stage I of NVP was 69.56% and specificity was 96.35%. Calculated sensitivity of the PUQE scoring system to diagnose Stage II of NVP was 100% and specificity was 78.78%. All pregnant women who were clinically detected as Stage II NVP patients were detected as Stage II NVP patients by the PUQE scoring system also. None of the false positives and false negatives regarding Stage II of NVP detected by the PUQE scoring system. Conclusion: First line antiemetics and oral rehydration solutions are usually used for treating pregnancy-related nausea and vomiting. Stage II NVP conditions were detected with a higher prevalence when NVP status was diagnosed clinically and with PUQE scoring system. Specificity of PUQE scoring system appeared higher while detecting NVP Stage I and for NVP Stage II, sensitivity of PUQE scoring system appeared high. For Stage III NVP, clinical judgments and PUQE scoring system values were completely compatible. Management strategies used for treating pregnancy-related hyperemesis status should be further studied. Conducting these studies at different study settings may help to achieve more successful results. Pregnancy unique quantification of emesis tool can be used to diagnose NVP status more descriptively. Also, this PUQE tool is a valid tool which can be effectively used for patient management. Application of PUQE scoring system should be published by planning and implementing staff awareness programs for both curative sector and public health sector.

Use of the Modified Pregnancy -Unique Quantification of Emesis Score to Evaluate the Need for Admission and Response to Treatment in women with Hyperemesis Gravidarum

Use of the Modified Pregnancy -Unique Quantification of Emesis Score to Evaluate the Need for Admission and Response to Treatment in women with Hyperemesis Gravidarum

Guidelines for Treatment of Hyperemesis Gravidarum and Implementation in Clinical Practice in Norway: A Descriptive Study

Background. The severe pregnancy complication hyperemesis gravidarum (HG) requires intravenous fluids, antiemetics, and nutrition to prevent maternal and fetal complications. Several guidelines exist for the treatment of HG within and across countries. The aim of this study was to investigate whether the guideline issued by the Norwegian Society for Obstetrics and Gynecology (NGF) was implemented in clinical practice by comparing department treatment protocols and assessing provided treatment. Methods. Department protocols for the treatment of HG were requested from all Norwegian gynecology departments and compared to the NGF guideline regarding the use of Pregnancy Unique Quantification of Emesis (PUQE-24) score, antiemetics, thiamine, and fluid and nutritional therapy. Additionally, we performed a retrospective chart review of provided treatment during 2017–2019 at four hospitals. Results. In all, 28 of 39 (72%) departments replied, of which 11 reported using the NGF guidelines unaltered. Of the 17 local department protocols in use, 16 closely resembled the NGF guidelines regarding the use of PUQE score, fluid therapy, nutritional treatment, and thiamine. Eight department protocols differed slightly from the NGF guidelines regarding the antiemetic medication treatment pathway, and two recommended antiemetic medication not supported by national or international guidelines. The retrospective chart review of 343 patients at four hospitals showed that the provided care aligned with the guidelines regarding intravenous fluids and the use of PUQE score, and the use of antiemetics mostly aligned with the treatment pathway provided in the NGF guideline. However, the proportion of patients receiving ondansetron varied between 32% and 79% and thiamine from 38 to 86% between hospitals. Overall, few patients were provided with nutritional treatment by partial peripheral nutrition (14%), enteral tube feeding (8%), or total parenteral nutrition (1.5%). Conclusion. The NGF guideline was used unaltered or largely integrated in department protocols. Treatment data suggest that the guideline was implemented in clinical practice, but differences in the provision of ondansetron and thiamine suggest geographical inequality of care. Infrequent use of nutritional treatment by parenteral nutrition or enteral feeding tube could suggest improvements in pharmacological symptom management or undertreatment of malnutrition.

Association of the 24-hour Pregnancy Unique Quantification of Emesis Index with Self-Rated Wellbeing Score: A Cross-Sectional Study

Introduction: Nausea and Vomiting of Pregnancy (NVP) are common symptoms of pregnancy. Often, treatment is guided by subjective symptoms, leading to hospitalisation of these patients and unnecessary health costs. The 24-hour Pregnancy-Unique Quantification of Emesis (PUQE) index helps objectively quantify these symptoms and guide the management of these patients. Aim: To assess the association of the 24-hour PUQE index with the self-rated well-being score in evaluating the severity of NVP. Materials and Methods: In this cross-sectional study, a total of 207 women at 5 to 12 weeks of singleton pregnancy were recruited after obtaining informed consent. They were interviewed regarding their symptoms of nausea and vomiting based on a 24-hour PUQE index questionnaire, and a score was assigned to them. They were stratified as mild, moderate, or severe based on the score. The association of these symptoms with a selfrated well-being score and subjective symptoms such as the ability to take multivitamins, sleep pattern, liquid intake, and the need for hospitalisation was assessed. They were followed-up after four weeks, and a repeat score was obtained. Chi-square test was performed to compare the severity of PUQE-24. Results: The mean well-being score at the first visit was 3.381±1.650, and at the follow-up visit, it was 7±1.763. At the first visit, 46 out of 207 had a mild 24-hour PUQE score, 140 out of 207 had a moderate score, and 21 out of 207 had a severe score. During the follow-up visit, 123 out of 207 had a mild score, 77 out of 207 had a moderate score, and seven out of 207 had a severe score. There was a significant association between the mean self-rated well-being score and the 24-hour PUQE score at the first and follow-up visits (p-value=0.0001). Among the patients hospitalised at the first visit (21 out of 28), 75% belonged to the severe PUQE category. The mean liquid intake at the first visit was 24.363±10.357 mL/kg/hr, and at the followup visit was 29.972±10.691, showing a significant association with the severity of the 24-hour PUQE score (p-value=0.0001). A significant association was observed between the 24-hour PUQE scores of the first and follow-up visits (p-value=0.002). Conclusion: In this study, there was a significant association between the 24-hour PUQE score and the well-being score at both visits. Stratifying the severity of NVP objectively will guide us to choose the appropriate treatment and reduce the need for hospitalisation.

Ffect Peppermint Aromatherapy Inhalation Reducing Nausea And Vomiting In First Trimester Of Pregnancy

The Nausea and vomiting in pregnant women in the first trimester was physiologically due to an increase in the Human Chorionic Gonadotrophin (HCG) hormone which affects the digestive system, causing complaints of nausea and vomiting. One of them was handling nausea and vomiting by administering peppermint aromatherapy inhalation. Peppermint had a sharp menthol aroma, a distinctive cold refreshing smell, and the smell of menthol which had properties against contractions by inhibiting muscle contact caused by serotonin hormone so that it could successfully overcome nausea and vomiting in pregnant women. This study aims to determine the differences in nausea and vomiting before and after administration of peppermint aromatherapy inhalation dose, 0,1-0,2 ml for 1-10 minutes to pregnant women in their first This type of research was quasi-experimental, one-group pre-and post-test design. The number of samples was 48 respondents intervention and treatments, with the sampling method "purposive sampling" type of non-probability sampling. The data collection tool was a Pregnancy Unique Quantification of Emesis and Nausea (PUQE) questionnaire. Data analysis techniques used univariate and bivariate analysis. The results of data analysis used the Wilcoxon test and obtained a p-value of 0. 000 p 0. 05. This means that there were differences in nausea and vomiting before and after giving peppermint aromatherapy inhalation to pregnant women in their first trimester. It is expected that pregnant women use peppermint aromatherapy inhalation to treat nausea and vomiting because it does not have a toxic effect on the health of the mother and fetus.

The effect of dayak ginger (<i>Zingiber Officinale Roscoe</i>) extraction in ginger cookies in reducing emesis gravidarum severity among pregnant women

One of the discomforts during pregnancy is nausea and vomiting, known as emesis gravidarum. Ginger cookies, as a Complementary Alternative Medicine (CAM), are often consumed by pregnant women to alleviate nausea. The purpose of this study was to investigate the effect of ginger cookies on pregnant women experiencing emesis gravidarum. This research was conducted as a Randomized Control Trial (RCT), following the CONSORT Guidelines. The study involved 59 pregnant women with a gestational age ranging from 6 to 16 weeks who were experiencing nausea and vomiting. The subjects were selected using random sampling. The intervention involved providing ginger cookies for a duration of 3 weeks. The severity of emesis gravidarum was assessed using the Pregnancy Unique Quantification of Emesis and Nausea (PUQE) questionnaire. Data analysis was carried out using an Independent Sample t-test. The results revealed a significant difference in the average severity of hyperemesis between the treatment and control groups (p < 0.001), indicating a significant difference in emesis gravidarum severity between the intervention and control groups. In conclusion, ginger cookies have been shown to reduce the severity of emesis gravidarum. They can be considered as an adjunct in providing behavioral education to pregnant women to prevent emesis gravidarum.

Relationship between combined systemic inflammatory indices with presence and severity of hyperemesis gravidarum.

Our study aims to determine the levels of systemic inflammation markers and the combined systemic inflammation indices in hyperemesis gravidarum (HG) patients and to investigate the association between the severity of the disease. The study population consisted of 83 pregnant women with HG and 100 healthy pregnant women matched for gestational age as a control group. We grouped the HG patients according to the Modified Pregnancy Unique Quantification of Emesis/Nausea (PUQE) scoring system as mild, moderate, and severe. We calculated the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), MPV-to-lymphocyte ratio (MPVLR), RDW-to-platelet ratio (RPR), Systemic immune-inflammation index (SII), Systemic Inflammation Response Index (SIRI), and Aggregate Systemic Inflammation Index (AISI). NLR, PLR, SII, SIRI, and AISI levels were significantly higher in the HG group. These indices tended to increase as the severity of the disease increased. We found NLR, PLR, SII, SIRI, and AISI indices as the independent risk factors for the presence and severity of HG. The SIRI index, which has the highest area under the curve (AUC), sensitivity, and specificity values, was determined as the most powerful diagnostic tool in the diagnostic evaluation of the presence (AUC: 0.695; p < 0.001; sensitivity: 54%; specificity: 75%; cut-off: 3.14) and severity (AUC: 0.785; p < 0.001, sensitivity: 82%; specificity: 68%; cut-off: 2.74) of HG. Our study results showed that combined systemic inflammatory indices (NLR, PLR, SII, SIRI, and AISI) are associated and correlated with the presence and severity of HG. These indices are independent risk factors for the presence and severity of HG. Combined systemic inflammatory indices are diagnostic in determining the severity of HG. The SIRI index has the best diagnostic power for both the diagnosis of HG and the determination of the severity of HG.

The Nutritional Online sUrvey for pRegnancy Induced Sickness & Hyperemesis (NOURISH) study: results from the first trimester.

Hyperemesis gravidarum (HG) is severe pregnancy sickness, often leading to dehydration, weight loss and electrolyte disturbances. Little is known about nutritional intake and its consequences in those affected. The aim of this study was to explore the first trimester nutritional intake and clinical characteristics in those with severe sickness. Recruitment was via the social media accounts of national pregnancy charities. The eligibility criteria were as follows: between 6 and 11 weeks pregnant, age ≥18 years and residing in the UK. Participants completed a self-report online questionnaire including the Pregnancy Unique Quantification of Emesis 24 (PUQE24) score and a 3-day online diet diary. Groups were compared by PUQE24 categories. Nutritional intakes were compared to dietary reference values. One hundred sixty-six participants took part in the study: 36 categorised with mild, 109 with moderate and 21 with severe symptoms at a median gestation of 8.1 (interquartile range [IQR] 3) weeks. Those in the severe category had significantly higher weight loss (3.0 kg, IQR 3.5) than the mild category (0.0 kg, IQR 0.9). In those who completed the diet diary (n = 70), intakes of energy, carbohydrate, protein, fat, fibre, calcium, iron, zinc, thiamine, riboflavin, folate and vitamin C were all significantly lower in the severe category (p < 0.05). The severe group consumed only 39.5% and 41.6% of energy and protein needs, respectively, and were more likely to stop taking micronutrient supplements (p < 0.05). Nutritional and supplement intake in those with severe pregnancy sickness was poor; however, intake across all participants was suboptimal. Future research should investigate how to improve nutritional intake across all categories of pregnancy sickness.

The Role Of Systemic Immune-Inflammation Index In The Severity Of Hyperemesis Gravidarum.

Hyperemesis gravidarum(HEG) is one of the severe health problems in early pregnancy. Obstetricians should be aware of systemic inflammation in HEG patients to provide better preventive strategies. Hyperemesis gravidarum(HEG) is one of the most common causes of hospitalization in early pregnancy. Complete blood count parameters can be used as inflammatory markers in patients with HEG. We aimed to investigate the Systemic Immune-Inflammation Index (SII)in predicting the severity of HEG. This cross-sectional study was performed with 469 pregnant women diagnosed and hospitalized with HEG. The study parameters were calculated from complete blood count tests and urine analysis. Demographic characteristics, the Pregnancy Unique Quantification of Emesis (PUQE) scale values, and ketonuria levels at hospital admission were recorded. The neutrophil‑to‑lymphocyte ratio (NLR), platelet‑to‑lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and SII, calculated by the formula (neutrophil × platelet/lymphocyte), were evaluated for predicting the severity of HEG. There was a positive correlation between the increased degree of ketonuria and SII. The cut-off value of SII for predicting the severity of HEG was 1071.8 (AUC 0.637, 95% CI (0.582-0.693), p<.001), and sensitivity and specificity were 59% and 59%, respectively. The cut-off value of SII to predict the length of hospitalization was 1073.6(AUC: 0.565, 95% CI: (0.501-0.628), p= 0.039); sensitivity and specificity were 56.3% and 55.5%, respectively CONCLUSIONS: : The clinical utility of SII in predicting HEG severity is limited due to relatively low sensitivity and specificity. Further research is needed to determine the importance of inflammatory indices in HEG patients.

The effectiveness of the application of self-hypnosis and prenatal gentle yoga on emesis gravidarum in the first-trimester pregnant women

Background: Emesis gravidarum is an inconvenience that often occurs in the first trimester of pregnancy. Continuous emission of gravidarum can be bad for the health of pregnant women and the fetus is conceived, so it must be overcome as early as possible, one of which can use non-pharmacological therapy, namely applying self-hypnosis and prenatal gentle yoga to reduce emissions of gravidarum can make pregnant women relax. This study aimed to analyze the application of self-hypnosis with Prenatal Gentle Yoga on emissions of gravidarum in first-trimester pregnant women. Methods: The design of this study used a Quasi experimental design with a Two group pretest-posttest design without control using purposive sampling. This research was conducted on first-trimester pregnant women who experienced the emission of gravidarum in the PMB Nanik Sidoarjo of ​​32 pregnant women in the first trimester. The self-hypnosis was carried out every day for approximately 15-30 minutes for 1 week, while prenatal yoga was carried out 3 times a week for 30 minutes. Data collection on the intensity of nausea and vomiting used the Pregnancy Unique Quantification of Emesis and Nausea (PUQE)-24 scoring system questionnaire. Data analysis used an independent T-Test test. Results: The results of the analysis of this study indicate that the mean difference in the Self Hypnosis treatment group is greater (1.77) than in the Prenatal Gentle Yoga group (1.25), which means that Self Hypnosis is more effective in reducing the intensity of nausea and vomiting in emesis gravidarum versus Prenatal Gentle Yoga. Conclusion: Therapy Self Hypnosis and Prenatal Gentle Yoga can reduce the emission level of gravidarum in first-trimester pregnant women so that it can be used as an alternative therapy that is easy to apply and has minimal side effects by pregnant women who experience gravidarum emissions.

Modern perspectives in Proof Theory.

Modern perspectives in Proof Theory.

Pengaruh Permen Jahe dalam Mengatasi Keluhan Mual dan Muntah pada Ibu Hamil

Pregnancy is a natural process that causes physical and psychological changes due to hormonal changes. Often pregnancy enters a critical period if it is not passed comfortably by pregnant women. Pregnant women must be able to adapt psychologically and physiologically to pregnancy hormones. The effect of hormonal changes is nausea and vomiting in early pregnancy, especially in the morning. Nausea and vomiting can be reduced by using herbal ingredients. The method used in this study was a literature study on the benefits of ginger, then ginger was processed into ginger candies with added sugar and water. The ginger candy was then given to women who were pregnant for 4 days in the first trimester of pregnant women. Nausea and vomiting were measured before and after being given the ginger candy using the Pregnancy Unique Quantification of Emesis and Nausea (PUQE) instrument. The data were processed statistically to determine the effect of extra ginger candy on nausea and vomiting of pregnant women. After measuring the pretest and posttest giving ginger candy, it was concluded that there was an effect of ginger candy on reducing nausea and vomiting.

The Effectiveness Of Warm Ginger Therapy In Overcoming Emesis Gravidarum In Pregnant Women

According to the World Health Organization (WHO), hyperemesis gravidarum occurs throughout the world, including the countries of the Americas with varying incidence rates ranging from 0.5-2%, 0.3% in Sweden, 0.5% in California, 0.8% in Canada, 10.8% in China, 0.9% in Norway, 2.2% in Pakistan and 1.9% in Turkey. Meanwhile, the incidence of hyperemesis gravidarum in Indonesia ranges from 1-3% of all pregnancies. The purpose of this study was to determine the effectiveness of giving warm ginger to the frequency of Emesis gravidarum in first trimester pregnant women. The type of research used was quantitative research with Pre-Experimental research design using One Group Pretest-Posttest design. The population in this study were all first trimester pregnant women who experienced emesis gravidarum who had their pregnancy checked at BPM Happy Purnama. Sampling in this study used a total sampling technique with a sample of 16 people. Data collection was obtained by using the Pregnancy Unique Quantification of Emesis questionnaire. The statistical results of the study obtained a p-value of 0.002, which means it is smaller than the significant value, which is &lt;0.05, so it can be concluded that giving warm ginger is effective in reducing the frequency of emesis gravidarum. This study is also expected to be an alternative non-pharmacological treatment of emesis gravidarum in first trimester pregnant women.

Тошнота и рвота беременных: влияние на качество жизни

Objective. To examine the relationship between nausea and vomiting of pregnancy (NVP) of varying severity and health-related quality of life (QoL), as well as the efficacy of improving it with the Preginor® complex. Patients and methods. A prospective cohort study enrolled 94 women at 6 to 16 weeks’ gestation with mild to moderate nausea and/or vomiting. The clinical status of patients and QoL were assessed by questionnaire before, during and after administration of Preginor® with evaluating the Pregnancy–Unique Quantification of Emesis and Nausea/PUQE index and socioeconomic status, habits, and lifestyle from specialized questionnaires. Results. Based on the total PUQE index, 69.1% of pregnant women had mild nausea and vomiting. Moderate NVP accounted for 30.9%. No cases of severe NVP that might require hospitalization were identified. In the calculation, the average PUQE score before the use of Preginor® was 6.5. By the end of treatment, the mean value of NVP index decreased by 2.2 times; 37.2% of patients had no complaints, while 55.3% only experienced mild nausea. In 7.5% of women, even with the persistence of moderate manifestations of NVP, their intensity was significantly reduced, improving the general condition of pregnant women and increasing their QoL. In some patients, the Preginor® complex could be continued for more than 1 month upon the recommendation of the attending physician. Conclusion. According to the data presented, NVP, the intensity of which can be measured by the PUQE index, has a significant impact on various aspects of women’s lives, including global QoL, day-to-day aspects, and readiness to become pregnant again. A decrease in this index during the treatment of NVP is associated with an improvement in physical and mental QoL. For this reason, the NVP-specific PUQE index can be a very useful tool in clinical practice. The use of Preginor® complex for nausea and vomiting during pregnancy, significantly alleviating these symptoms, improves patients’ quality of life and daily activities. Key words: nausea, vomiting, pregnancy, antiemetics, ginger, Preginor®, quality of life

EFFECT OF LEMON AROMATHERAPY ON DECLINE NAUSEA AND VOMITING IN PREGNANT WOMEN IN THE FIRST TRIMESTER AT THE ABEPURA HEALTH CENTER IN JAYAPURA CITY

Background: Vomiting and nausea in the first trimester of pregnancy is often experienced by pregnant women, if the symptoms occur continuously it will have an impact on pregnancy and the process of fetal growth and development. One of the safe and doable non-pharmacological therapies is the administration of lemon aromatherapy.&#x0D; Objective: This study aims to determine the effect of lemon aromatherapy on reducing nausea and vomiting in pregnant women in the 1 trimester&#x0D; Methods: This type of research is pre-experimental with quasi-experimental design. The design is using two group pretest posttests as a treatment in the intervention group to be given lemon aromatherapy and a control group that was not intervened. The population was 28 pregnant women, with the sample being the total population divided into 2 groups using purposive sampling techniques. Data were obtained using the Pregnancy Unique Quantification of Emesis/Nausea (PUQE) Scale questionnaire to measure the frequency of nausea and vomiting before and after two weeks of aromatherapy. Data analysis using the Wilcoxon Signed Rank Test.&#x0D; Results: The results showed that there was an effect of lemon aromatherapy on reducing nausea and vomiting in 1 trimester pregnant women where statistical tests showed a value Sig (2 tailed)=0,000 &lt; α 0,05 then Ha is accepted.&#x0D; Conclusion: There is an effect of lemon aromatherapy on the decrease in nausea and vomiting in 1 trimester pregnant women

Disability during Early Pregnancy: Using the Sheehan Disability Scale during the First Trimester in Japan.

Background: Many pregnant women experience impairments in social, occupational, or other important functioning. Aim: This study aimed to confirm measurement and structural invariance of the Sheehan Disability Scale (SDS) and its validity during early pregnancy. Design: Longitudinal study with two observations. Methods: Questionnaires were distributed to pregnant women attending antenatal clinics at gestational weeks 10-13. Of 382 respondents, 129 responded to the SDS again 1 week later. Results: Confirmatory factor analysis shows good fit with the data: χ2/df = 0, comparative fit index (CFI) = 1.000, standardized root mean square residual (SRMR) = 0, and root mean square error of approximation (RMSEA) = 0.718. There is acceptable configural, measurement, and structural invariance of the factor structure between primiparas and multiparas as well as between two observation occasions. The Pregnancy-Unique Quantification of Emesis and Nausea, Patient Health Questionnaire-9, and Insomnia Severity Index subscales explain 47% of the variance in SDS scores. Conclusion: Perinatal health care professionals should pay more attention to the difficulties and disabilities that pregnant women face.

Clinical Efficacy of Modified Pregnancy Unique Quantification of Emesis (PUQE Score) in Managemenet of Emesis of Pregnancy

Clinical Efficacy of modified Pregnancy Unique Quantification of Emesis (PUQE score) in managemenet of emesis of pregnancy. Aims: To study PUQE score in ANC patients till 12 weeks, attending OPD or emergency department. To triage the patient as mild, moderate and severe case and to treat them accordingly. Settings and Design: Study was conducted in the Department of Obstetrics and Gynaecology in a tertiary care hospital. An Observational analytical study. The study included all the women with emesis in pregnancy from 1st September 2019 to 30th September 2021 matching the inclusion and exclusion criteria Study included all the women having emesis in pregnancy attending antenatal OPD and Emergency Medical Department, till 12 weeks.

Impact of a Mobile Application for Tracking Nausea and Vomiting During Pregnancy (NVP) on NVP Symptoms, Quality of Life, and Decisional Conflict Regarding NVP Treatments: MinSafeStart Randomized Controlled Trial.

BackgroundPregnant women are active users of mobile apps for health purposes. These apps may improve self-management of health-related conditions. Up to 70% of pregnant women experience nausea and vomiting (NVP). Even mild NVP can significantly reduce quality of life (QoL), and it can become an economic burden for both the woman and society. NVP often occurs before the first maternal care visit; therefore, apps can potentially play an important role in empowering pregnant women to recognize, manage, and seek appropriate treatment for NVP, when required.ObjectiveThis study investigated whether the MinSafeStart (MSS) mobile app could impact NVP-related symptoms, QoL, and decisional conflict regarding NVP treatment.MethodsThis randomized controlled trial enrolled 268 pregnant women with NVP in Norway from 2019 to 2020. The intervention group had access to the MSS app, which could be used to track NVP symptoms and access tailored advice. NVP severity was rated with the Pregnancy Unique Quantification of Emesis (PUQE) score. The control group followed standard maternal care. We collected data on maternal baseline characteristics, NVP severity, QoL, and decisional conflict using 2 sets of online questionnaires. One set of questionnaires was completed at enrollment, and the other was completed after 2 weeks. We performed linear regression analyses to explore whether the use of the MSS app was associated with NVP severity, QoL, or decisional conflict.ResultsAmong the 268 women enrolled in the study, 192 (86.5%) completed the baseline questionnaires and were randomized to either the intervention (n=89) or control group (n=103). In the intervention group, 88 women downloaded the app, and 468 logs were recorded. In both groups, women were enrolled at a median of 8 gestational weeks. At baseline, the average PUQE scores were 4.9 and 4.7; the average QoL scores were 146 and 149; and the average DCS scores were 40 and 43 in the intervention and control groups, respectively. The app had no impact on NVP severity (aβ 0.6, 95% Cl −0.1 to 1.2), QoL (aβ −5.3, 95% Cl −12.5 to 1.9), or decisional conflict regarding NVP treatment (aβ −1.1, 95% Cl −6.2 to 4.2), compared with standard care.ConclusionsTracking NVP symptoms with the MSS app was not associated with improvements in NVP symptoms, QoL, or decisional conflict after 2 weeks, compared with standard care. Future studies should include a process evaluation to improve our understanding of how pregnant women use the app and how to optimize its utility within maternity care. Specifically, studies should focus on how digital tools might facilitate counseling and communication between pregnant women and health care providers regarding NVP management during pregnancy.Trial RegistrationClinicalTrails.gov (NCT04719286): https://www.clinicaltrials.gov/ct2/show/NCT04719286