Unique Property Research Articles

Исследование прочности клеевого соединения при облицовывании щитовых деталей мебели каменным шпоном

Stone veneer has been known for a long time. But mostly it has been used as a finishing material, which is widely
 applied in decorating the outer surfaces of buildings and facilities. Stone veneer is a thin cut of natural stone - slate, which
 is applied to fiberglass or textiles. The thickness of the veneer is in the range of 2-3 mm. Stone veneer is available in the
 form of rolls or tiles. Due to its flexibility, it can be used to refine surfaces that have angles and small radius of curvature.
 The flexibility of stone veneer is a unique property, since natural stone is not flexible. In today’s world stone veneer is
 trying to find new fields of application. This material is used not only in interior and exterior designs, but also as a
 decorative coating of furniture panels. In this work we have established the possibility of wood board materials facing by
 stone veneer using standard technologies and the most common adhesives used in our country, such as urea-formaldehyde
 resin and polyvinyl acetate dispersion.

Tailoring pore size of mesoporous silica and organosilica using biodegradable pentablock copolymer templates via EISA process

In this work, we have designed unique poly(lactic acid-co-glycolic acid)-b-poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-poly(lactic acid-co-glycolic acid) pentablock copolymers using Pluronic F68 and F108 triblock copolymers as macroinitiators. The poly(lactic acid-co-glycolic acid) (PLGA) blocks were attached as glycolide and lactide monomers at the both ends of each F68 and F108 triblock copolymer. The molecular weights and the block fractions were confirmed by gel permeation chromatography (GPC) and proton nuclear magnetic resonance (1H NMR) for the four kinds of pentablock copolymers. Using these pentablock copolymers as templates, we synthesized mesoporous ethane-silicas as well as silicas by the evaporation-induced self-assembly (EISA) method. 1,2-bis(triethoxysily)ethane (BTEE) were used as an organosilica precursor. The mesoporous ethane-silica samples were characterized using synchrotron small angle X-ray scattering (SAXS), nitrogen sorption experiments, transmission electron microscopy (TEM), and solid-state 29Si CP-MAS NMR. Based on the experimental results, it was confirmed that the porosity and pore diameter can be varied with the PLGA weight fraction of the pentablock copolymer. It is due to the PLGA block in polymer forming the hydrophobic domain in micelles, which leads to the formation of increased pore size over 20 nm without any additive pore expander. In addition, it seems that as the organosilica precursor increases, the association number of block copolymers forming one micelle decreases, resulting in a decrease in pore size. In summary, the polymer template plays a vital part in tuning the structure of the mesoporous ethane-silica samples. Thus, the development of synthetic method of mesoporous organosilica materials using polymer templates with different topology is still challenging and can endow the unique structure and property for mesoporous organosilica for future applications.

Enhanced transfer performance of sun-facing diffractive sails in solar polar imager missions

A diffractive sail represents an advancement in solar sailing technology, capable of generating tangential radiation pressure force when oriented towards the sun. This unique property allows for varied radiation pressure distributions, making it a potential candidate for complex space missions. This paper delves into the transfer performance of the sun-facing diffractive solar sail in a solar polar imager mission.We establish both the radiation pressure force model and the time-optimal control problem specific to the sun-facing diffractive solar sail in interplanetary transfers. Applying an indirect method and a combined approach of parameter optimization with the direct method, we explore how different diffractive angles and acceleration capacities affect transfer times. This research offers insights to the design and fabrication of thin novel optical metamaterial films that efficiently diffract light at appropriate angles for potential solar sails in the solar polar imager mission. Compared with reflective sails, the diffractive sail demonstrates remarkable transfer efficiency and simplicity in attitude control, making it a more suitable choice in the solar polar imager mission.

Unique E2-binding specificity of artificial RING fingers in cancer cells

Ubiquitin (Ub)-conjugating enzymes (E2s) are involved in various pathways for Ub transfer and deubiquitinating activities. These enzymes are associated with cancers such as breast cancer which is the second deadliest type of malignancy among women. Here, we revealed the unique E2-binding property and the auto-ubiquitination of artificial RING fingers (ARFs). Circular dichroism spectra showed the characteristic structures of ARFs. The proline, lysine, leucine, threonine and cysteine (PKLTC) sequence of ARF was important for E2-recognition and its mutations induced obvious changes in the E2-binding specificity and the auto-ubiquitination activity of ARF. The ARF mutants were applicable to detection of most of E2 activities. Furthermore, adding the ARF mutant C35A to cancer cells promoted its auto-ubiquitination, leading to the preferential detection of E2 UbcH5b activity. The present work opens up a new avenue for investigating intracellular E2 activities for the fatal diseases.

Light-Triggerable and Gate-Tunable Negative Differential Resistance in Small Molecules Heterojunction.

Negative differential resistance (NDR), a phenomenon in which the current decreases when the applied voltage is increased, is attracting attention as a unique electrical property. Here, we propose a broad spectral photo/gate cotunable channel switching NDR (CS-NDR) device. The proposed CS-NDR device has superior linear gate-tunable NDR behavior and highly reproducible properties compared to the previously reported NDR devices, as the fundamental mechanism of the CS-NDR device is directly related to a charge transport channel switching by the linear increase of the applied drain voltage. We also experimentally demonstrate that the photoinduced NDR behavior of the CS-NDR device was derived from the grain boundaries of dinaphtho[2;3-b:2',3'-f]-thieno[3,2-b]thiophene. Furthermore, this work produces a 9 × 9 CS-NDR device array composed of 81 devices, providing the reproducibility and uniformity of the CS-NDR device. Finally, we successfully demonstrate the detection of text images with 81 CS-NDR devices using the proposed photo/gate cotunable NDR behavior.

Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication

PurposeMore than 90% of patients with diabetes worldwide are type 2 diabetes (T2D), which is caused by insulin resistance or impaired producing insulin by pancreatic β cells. T2D and its complications, mainly large cardiovascular (LCV) and kidney (Ne) complications, are the major cause of death in diabetes patients. Recently, the dysregulation of peripheral T cell immune homeostasis was found in most T2D patients. However, the characteristics of T-cell receptors (TCR) remain largely unexplored in T2D patients.Patients and methodsHere we investigated the TCR repertoire using high-throughput sequencing in peripheral blood collected from T2D patient with (8 LCV and 7 Ne) or without complications.ResultsOur analysis of TCR repertoires in peripheral blood samples showed that TCR profiles in T2D patients with complications tended to be single and specific compared to controls, according to the characteristics of TCR repertoire in V-J combination number, diversity, principal component analysis (PCA) and differential genes. And we identified some differentially expressed V-J gene segments and amino acid clonotypes, which had the potential to contribute to distinguishing T2D patient with or without complications. As the progression of the disease, we found that the profiling of TCR repertoire was also differential between T2D patients with LVD and Ne complications base on this pilot analysis.ConclusionThis study demonstrated the protentional unique property of TCR repertoire in peripheral blood of T2D patient with and without complications, or T2D patients with LVD and Ne complications, which provided the possibility for future improvements in immune-related diagnosis and therapy for T2D complications.

Macroporous Directed and Interconnected Carbon Architectures Endow Amorphous Silicon Nanodots as Low-Strain and Fast-Charging Anode for Lithium-Ion Batteries

HighlightsMPCF@VG@SiNDs/C, constructed by uniformly dispersing amorphous Si nanodots in carbon nanospheres that are welded on the wall of the macroporous carbon frameworks by vertical graphene, is synthesized and has achieved a few kilogram production per batch.Finite element imitation reveals that amorphous Si nanodots with high dispersity in carbon nanosphere can achieve ultra-low stress and strain values during lithiation.Unique low-strain property and fast-charging capability are achieved under industrial electrode conditions.

Prediction of Surgical Outcomes in Normal Pressure Hydrocephalus by MR Elastography.

Normal pressure hydrocephalus is a treatable cause of dementia associated with distinct mechanical property signatures in the brain as measured by MR elastography. In this study, we tested the hypothesis that specific anatomic features of normal pressure hydrocephalus are associated with unique mechanical property alterations. Then, we tested the hypothesis that summary measures of these mechanical signatures can be used to predict clinical outcomes. MR elastography and structural imaging were performed in 128 patients with suspected normal pressure hydrocephalus and 44 control participants. Patients were categorized into 4 subgroups based on their anatomic features. Surgery outcome was acquired for 68 patients. Voxelwise modeling was performed to detect regions with significantly different mechanical properties between each group. Mechanical signatures were summarized using pattern analysis and were used as features to train classification models and predict shunt outcomes for 2 sets of feature spaces: a limited 2D feature space that included the most common features found in normal pressure hydrocephalus and an expanded 20-dimensional (20D) feature space that included features from all 4 morphologic subgroups. Both the 2D and 20D classifiers performed significantly better than chance for predicting clinical outcomes with estimated areas under the receiver operating characteristic curve of 0.66 and 0.77, respectively (P < .05, permutation test). The 20D classifier significantly improved the diagnostic OR and positive predictive value compared with the 2D classifier (P < .05, permutation test). MR elastography provides further insight into mechanical alterations in the normal pressure hydrocephalus brain and is a promising, noninvasive method for predicting surgical outcomes in patients with normal pressure hydrocephalus.

New type of the unique continuation property for a fractional diffusion equation and an inverse source problem

In this work, a new type of the unique continuation property for time-fractional diffusion equations is studied. The proof is mainly based on the Laplace transform and the properties of Bessel functions. As an application, the uniqueness of the inverse problem in the simultaneous determination of spatially dependent source terms and fractional order from sparse boundary observation data is established.

A cellulose nanocrystal-carbon dots@cholestrol fluorescent probe for imaging of plasma membrane with extended time scale

Despite the advancement of plasma membrane imaging techniques, there is an unmet need for fluorescent probes which can “light up” the lipid bilayer with an extended time scale. In this work, a novel fluorescent probe is developed for imaging of plasma membrane. The probe comprises a cellulose nanocrystal (CNC) scaffold derived from low-cost wood pulp, carbon dots (CDs) fluorophore that is in-situ synthesized on the surface of CNC, and cholesterol (Chol) ligand with aminated polyethylene glycol (PEG) spacer. In the CNC-CDs@PEG-Chol configuration, the Chol ligand provides excellent binding affinity onto plasma membrane due to its hydrophobic nature, while CDs contribute to the marvelous optical stability, as well as the high quantum yield of the fluorescent probe. For CNC scaffold, their unique morphological property allows the assembling of dense Chol ligands, and more importantly, impedes the diffusions of imaging moieties into the cytoplasm. Therefore, the fluorescent probe is featured with remarkable specificity and satisfying plasma membrane imaging time window, which covers the co-incubation time from 30 to 90 min. In contrast, the mono-dispersed CDs@PEG-Chol probe can be facilely internalized by the cells at a co-incubation time as short as 20 min. CNC is proven to be responsible for the different imaging time scales by providing the confinement effects. The proposed fluorescent probe is believed to be a promising tool for studying the plasma membrane behaviors associated with cellular physiological processes.

Optical mode-controlled topological edge state in waveguide lattice

Abstract Topological edge state (TES) has emerged as a significant research focus in photonics due to its unique property of unidirectional transmission. This feature provides immunity to certain structural disorders or perturbations, greatly improving the robustness of photonic systems and enabling various applications such as optical isolation and topological lasers. Nevertheless, most of current researches focus on the fixed generated TES with no means to control, leaving untapped potential for manipulating the TES through specific methods. In this work, we propose a topological Su–Schriffer–Heeger (SSH) waveguides-lattice scheme that enables the controllable TES without changing the topological phase of the system. Light is selectively localized at the edges of the SSH waveguide lattice, which is determined by the special waveguide modes. Eventually, achieving an effective mode splitter. To validate our proposal, we further demonstrate such mode-controlled TES with a fabricated on-chip device in experiment. The experimentally tested results confirm a successful separation of the waveguide modes with the mode extinction ratio of approximately 10 dB in each channel near the wavelength of 1550 nm. This scheme presents a promising approach for manipulating the TES in photonic systems, thereby facilitating the design of optical controllable topological photonic devices.

Recent Advances in Synthesis of Non-Alternating Polyketone Generated by Copolymerization of Carbon Monoxide and Ethylene.

The copolymers of carbon monoxide (CO) and ethylene, namely aliphatic polyketones (PKs), have attracted considerable attention due to their unique property and degradation. Based on the arrangement of the ethylene and carbonyl groups in the polymer chain, PKs can be divided into perfect alternating and non-perfect alternating copolymers. Perfect alternating PKs have been previously reviewed, we herein focus on recent advances in the synthesis of PKs without a perfect alternating structure including non-perfect alternating PKs and PE with in-chain ketones. The chain structure of PKs, catalytic copolymerization mechanism, and non-alternating polymerization catalysts including phosphine-sulfonate Pd, diphosphazane monoxide (PNPO) Pd/Ni, and phosphinophenolate Ni catalysts are comprehensively summarized. This review aims to enlighten the design of ethylene/CO non-alternating polymerization catalysts for the development of new polyketone materials.

Improved Method to Estimating Parameters of a Poisson Hidden Markov Model Using Bayesian Approach

Expectation-Maximization (EM) is a popular method for estimating parameters of the Poisson-Hidden Markov Model (P-HMM). However, over-dispersion in comparison to the Poisson distribution remains a concern. This study developed a Bayesian method to Poisson count models. The study compares the Mean Square Errors and sufficiency of the EM to the Gibbs sampler technique using Akaike Information Criterion, Bayesian Information Criterion, and Deviance Information Criterion as model selectors. The Maximum Likelihood Estimates and Maximum a \textit{posteriori} were calculated using both simulated and real data in this case. The study&amp;#39;s findings indicate that using any of the two approaches depends on the data type and the sample size. Whereas the Poisson Hidden Markov model, which uses the EM algorithm is preferred when using Zero-inflated data with a sample size&amp;nbsp; n &amp;le; 20 , the Bayesian Poisson-Hidden Markov Model, which uses a Gibbs sampler is better used for Heavy and Mixture data types irrespective of the sample size. The model predicted parameters of simulated data with remarkable accuracy and produced some unique statistical property results. This method is applicable to Poisson-hidden Markov models with homogeneous time series.

Truth and the Unity of Logical Validity

According to a traditional view, logical validity consists in necessary truth preservation. Such an account has been argued to carry an apparent commitment to a unique property of truth to be preserved from premises to conclusion. Recent discussions, however, have concluded that if the metaphor of truth preservation is carefully unpacked, no need for a unique property is there. All is needed is that certain structural relations among instantiations of truth properties hold. Against this view, we argue that a unique general truth property is indeed required by logical validity. We first show that the unpacking should be correctly understood since it imposes constraints on the concept and the properties of truth. We then demonstrate that, under such constraints, a general property is not imposed by truth preservation but by another feature of validity: its uniformity. Finally, some options that could be attempted to resist this result are discussed, showing that (strong) truth pluralism and deflationism are affected in different ways.

Inactivation activity and mechanism of pulsed light against Alicyclobacillus acidoterrestris vegetative cells and spores in concentrated apple juice

Alicyclobacillus acidoterrestris has received much attention due to its unique thermo-acidophilic property and implication in the spoilage of pasteurized juices. The objective of this study was to evaluate the sterilization characteristics and mechanisms of pulsed light (PL) against A. acidoterrestris vegetative cells and spores in apple juice. The results indicated that bacteria cells in apple juice (8–20°Brix) can be completely inactivated within the fluence range of 20.25–47.25 J/cm2, which mainly depended on the soluble solids content (SSC) of juice, and the spores in apple juice (12°Brix) can be completely inactivated by PL with the fluence of 54.00 J/cm2. The PL treatment can significantly increase the leakage of reactive oxygen species (ROS) and proteins from cells and spores. Fluorescence studies of bacterial adenosine triphosphate (ATP) indicated that the loss of ATP was evident. Scanning electron microscopy and confocal laser scanning microscope presented that PL-treated cells or spores had serious morphological damage, which reduced the integrity of cell membrane and led to intracellular electrolyte leakage. In addition, there were no significant negative effects on total sugars, total acids, total phenols, pH value, SSC and soluble sugars, and organic acid content decreased slightly during the PL treatment. The contents of esters and acids in aroma components had a certain loss, while that of alcohols, aldehydes and ketones were increased. These results demonstrated that PL treatment can effectively inactivate the bacteria cells and spores in apple juice with little effect on its quality. This study provides an efficient method for the inactivation of A. acidoterrestris in fruit juice.

One-Pot Synthesis of a Robust Crosslinker-Free Thermo-Reversible Conducting Hydrogel Electrode for Epidermal Electronics.

Traditional epidermal electrodes, typically made of silver/silver chloride (Ag/AgCl), have been widely used in various applications, including electrophysiological recordings and biosignal monitoring. However, they present limitations due to inherent material mismatches with the skin. This often results in high interface impedance, discomfort, and potential skin irritation, particularly during prolonged use or for individuals with sensitive skin. While various tissue-mimicking materials have been explored, their mechanical advantages often come at the expense of conductivity, resulting in low-quality recordings. We herein report the facile fabrication of conducting and stretchable hydrogels using a "one-pot" method. This approach involves the synthesis of a natural hydrogel, termed Golde, composed of abundant and eco-friendly components, including gelatin, chitosan, and glycerol. To enhance the conductivity of the hydrogel, various conducting materials, such as poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS), thermally reduced graphene (TRG), and MXene, are introduced. The resulting conducting hydrogels exhibit remarkable robustness, do not require crosslinkers, and possess a unique thermo-reversible property, simplifying the fabrication process and ensuring enhanced long-term stability. Moreover, their fabrication is sustainable, as it employs environmentally friendly materials and processes while retaining their skin-friendly characteristics. The resulting hydrogel electrodes were tested for electrocardiogram (ECG) signal acquisition and outperformed commercial electrodes even when implemented in an all-flexible electrode setup simply using copper tape, owing to their inherent adhesiveness.

Further results on generalized cellular automata

Given a finite set A and a group homomorphism ϕ : H → G , a ϕ -cellular automaton is a function T : A G → A H that is continuous with respect to the prodiscrete topologies and ϕ -equivariant in the sense that h · T ( x ) = T ( ϕ ( h ) · x ) , for all x ∈ A G , h ∈ H , where · denotes the shift actions of G and H on A G and AH , respectively. When G = H and ϕ = id , the definition of id -cellular automata coincides with the classical definition of cellular automata. The purpose of this paper is to expand the theory of ϕ -cellular automata by focusing on the differences and similarities with their classical counterparts. After discussing some basic results, we introduce the following definition: a ϕ -cellular automaton T : A G → A H has the unique homomorphism property (UHP) if T is not ψ-equivariant for any group homomorphism ψ : H → G , ψ ≠ ϕ . We show that if the difference set Δ ( ϕ , ψ ) is infinite, then T is not ψ-equivariant; it follows that when G is torsion-free abelian, every non-constant T has the UHP. Furthermore, inspired by the theory of classical cellular automata, we study ϕ -cellular automata over quotient groups, as well as their restriction and induction to subgroups and supergroups, respectively.

Light-Driven Sign Inversion of Circularly Polarized Luminescence Enabled by Dichroism Modulation in Cholesteric Liquid Crystals.

Stimuli-responsive circularly polarized luminescence (CPL) materials show great promise in applying information encryption and anticounterfeiting. Herein, light-driven CPL sign inversion is achieved by combining a photoresponsive achiral negative dichroic dye (KG) and a static achiral positive dichroic dye (NR) as dopants at the 0.5:0.5 weight ratio into the cholesteric liquid crystal (CLC) host. The side chains of KG undergo trans/cis isomerization after 365nm UV light irradiation, leading to the dichroism (SF ) decrease. The |glum | value of CLC doping with KG (CLC-KG) weakens from 0.67 to 0.28 in response to the order degree change. Taking advantage of its unique CPL response property, the light-driven CPL sign inversion is achieved (from -0.20/0.14 to 0.02/-0.04) by incorporating NR (0.5:0.5) into the CLC-KG with helical superstructure static. Based on the synergistic use of circular polarization and responsiveness state as cryptographic primitives, the multidimensional information encryption CLC system can be realized.

Inflammation-Targeted Drug Delivery Strategies via Albumin-Based Systems.

Albumin, being the most abundant serum protein, has the potential to significantly enhance the physicochemical properties of therapeutic payloads, thereby improving their pharmacological effects. Apart from its passive transport via the enhanced permeability and retention effect, albumin can actively accumulate in tumor microenvironments or inflammatory tissues via receptor-mediated processes. This unique property makes albumin a promising scaffold for targeted drug delivery. This review focuses on exploring different delivery strategies that combine albumin with drug payloads to achieve targeted therapy for inflammatory diseases. Also, albumin-derived therapeutic products on the market or undergoing clinical trials in the past decade have been summarized to gain insight into the future development of albumin-based drug delivery systems. Given the involvement of inflammation in numerous diseases, drug delivery systems utilizing albumin demonstrate remarkable advantages, including enhanced properties, improved in vivo behavior and efficacy. Albumin-based drug delivery systems have been demonstrated in clinical trials, while more advanced strategies for improving the capacity of drug delivery systems with the help of albumin remain to be discovered. This could pave the way for biomedical applications in more effective and precise treatments.

Light‐assisted noncompetitive fluorescence immunoassay for photosensitive antibiotic detection

AbstractThe development of simple, sensitive, and efficient methods for antibiotic detection is of great significance for human health and environmental protection. Currently, although the competitive immunoassays are popular for detecting antibiotic molecules, they need to label antibiotic or specific antibody with signaling molecule. The development of noncompetitive immunoassay for antibiotic detection has always faced significant challenges. Herein, we have developed a light‐assisted noncompetitive immunoassay for the detection of antibiotics based on their photosensitive characteristic. Firstly, the antibody coated on the microplate specifically captures the target antibiotic. Afterward, under light irradiation, the captured photosensitive antibiotic produces reactive oxygen species (ROS), which oxidizes the added ROS dye to generate a fluorescent signal. Therefore, a noncompetitive immunoassay for antibiotic detection is achieved by utilizing the unique property of photosensitive antibiotics to generate ROS instead of labeling signaling molecules. By using antibiotics demeclocycline hydrochloride (DMCO) and polymyxin B (PMB) as research models, the proposed noncompetitive fluorescence immunoassay can specifically detect as low as 5 ng/mL DMCO and 70 ng/mL PMB, respectively. The light‐assisted noncompetitive immunoassay strategy opens a new avenue for simple, sensitive, label‐free, and high‐throughput detection of photosensitive antibiotics or photosensitive drugs.