This study investigated the relationship between openness to experience, conscientiousness and optimism in students’ academic work among senior secondary school student in university Demonstration Secondary School UDSS – Uniport. Openness to experience and conscientiousness were the independent variables while optimism in students’ academic work was the dependent variable two research questions and two corresponding hypotheses guided the study. Correlational research design was adopted. A sample of four hundred 400 students was drawn from the population using simple random sampling techniques. Data was collected using two instruments namely. Personality Traits Assessment Scale (PTAS) and optimism in Students Academic Work Assessment Scale (OSAWAS) multiple regression and Pearson Product Moment Correlation were used to answer the research question while ANOVA and t-test associated with multiple regression were used to test the null hypotheses at 0.05 level of significance. The study found that openness to experience and conscientiousness had showed a positive significant relationship with optimism in students’ academic work. Based on the findings, appropriate recommendations were made. Article visualizations: