The paper proposes a new method and algorithm for creating a photo map of the seabed from photographs obtained from on-board photo and video systems of autonomous uninhabited underwater vehicles during fulfillment of their various missions. This photo map is formed from photographs of the seabed by sequentially overlapping them. At the same time, data on the position of the underwater vehicle received from the on-board navigation system at the time of receipt of each photograph is used to position each photo image on the generated photo map. And to rotate and scale these photographic images, data on the orientation of the underwater vehicle in the global coordinate system and its height above the bottom, also obtained from the on-board navigation system, are used. To provide quick access to the photo map, it is proposed to store it on an on-board data storage device in the form of a tile map, widely used when creating interactive geographical maps, for example, Google Maps. However, the formation of a tile map is usually carried out on the basis of all the already received photographic images, as is done with satellite images, which cannot be applied on board underwater vehicles when data from the photo-video system is received sequentially. Therefore, a special algorithm has been developed and implemented that generates a tile map during the movement of the underwater vehicle and updates only the area of the tile map in which the photo is currently being taken. This minimizes the computational load and ensures the formation of a photo map of the bottom using standard on-board computing devices. The conducted semi-natural experiments with data obtained as a result of performing real missions using the MMT-3000 underwater vehicle confirmed the high efficiency of using the developed method and algorithm.