AbstractThis article is concerned with the sufficient and necessary conditions for the global uniform exponential stability (GUES) of a class of uncertain nonautonomous switched nonlinear systems (UNSNS), that is, systems with time‐varying uncertain information. To start with, based on a piecewise continuous scalar function and a piecewise differentiable uncertainty‐dependent Lyapunov function along the trajectories, we propose alternative sufficient and necessary conditions for the GUES of UNSNS. Afterwards, for removing the dependence on uncertain information of the required Lyapunov functions, we combine an uncertainty‐independent Lyapunov function with its right upper Dini derivative and the above piecewise continuous scalar function to further obtain other alternative sufficient and necessary conditions for the GUES of UNSNS. Note that our conditions release the requirement on negative definiteness of the time‐derivatives and Dini derivatives of Lyapunov functions respectively, which is illustrated by Example 1. Further, for the rational UNSNS, we propose a linear semidefinite programming based computable approach to mechanically verify our current theoretical results. In the end, the effectiveness of our theoretical results and mechanical approach are illustrated by two examples.