Letters and Corrections1 May 1981Undifferentiated Malignant NeoplasmsDAVID L. PAGE, M.D.DAVID L. PAGE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-94-5-710_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The responsiveness of some undifferentiated, malignant epithelial neoplasms to a chemotherapeutic protocol designed for germ cell neoplasms (1) is interesting and clinically useful. Assuming, however, that they are (or should even be called) neoplasms of germ cell origin because they respond to such a protocol and because they contain oncofetal antigens is not warranted. Such a posture supposes knowledge where there is little to be had. Undifferentiated neoplasms have perplexed students of tumor biology and classification for generations. We should confess our ignorance and call undifferentiated malignant neoplasms just that until we gain sufficient wisdom to reorder...Reference1. RICHARDSONSCHOUMACHERFIR RRM. The unrecognized extragonadal germ cell cancer syndrome. Ann Intern Med. 1981;94:181-6. LinkGoogle Scholar1. RICHARDSONSCHOUMACHERFER RRM. The unrecognized extragonadal germ cell cancer syndrome. Ann Intern Med. 1981;94:181-6. LinkGoogle Scholar2. ACKERMANAUSTBREDENBERGHANSONROGERS NJCVL. Problems in differentiating between pancreatic lymphoma and anaplastic carcinoma and their management. Ann Surg. 1976;184:705-8. CrossrefMedlineGoogle Scholar3. SWEETGOLOMB DH. The treatment of histiocytic lymphomas. Semin Oncol. 1980;7:302-9. MedlineGoogle Scholar4. BONADONNAMONFARDINI GS. Chemotherapy of non-Hodgkin's lymphomas. Cancer Treat Rev. 1974;1:167-81. CrossrefGoogle Scholar5. CORDERLEIMERTPANTHERELLIOT MJST. A phase II study of cis-platinum II diaminine dichloride in lymphoma. Proc Am Soc Clin Oncol. 1979;20:301. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Vanderbilt University School of Medicine Nashville, TN 37232 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGerm Cell CancersRONALD L. RICHARDSON, M.D. 1 May 1981Volume 94, Issue 5Page: 710-711KeywordsAntigensGerm cellsPostural control Issue Published: 1 May 1981 PDF downloadLoading ...