Undergoing Shoulder Arthroplasty Research Articles

Return to sport after reverse total shoulder arthroplasty is highly frequent: a systematic review

ImportanceOne of the most frequent concerns of the increasing number of patients undergoing shoulder arthroplasty is the possibility to resume sport after surgery.ObjectiveThe aim of this systematic review was to determine the rate of return to sport after reverse total shoulder arthroplasty (RSA) and the subjective level of performance.Evidence reviewThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed to perform this systematic review. A systematic electronic search was performed using the PubMed (MEDLINE), Embase and Cochrane Library databases. All the studies analysing the rates were pooled; data were extracted and statistically analysed. The eligibility criteria were studies with at least 20 adult patients recruited. All studies had to relate return to sports after RSA.FindingsA total of six studies were included for a total of 457 patients. Mean age and average follow-up were, respectively, 74.7 years (range 33–88 years) and 3.6 years (range 1–9.4 years). The mean rate of return to sport ranged from 60% to 93%. The mean time for resuming sports was 5.3 months. The overall rate of return to sport after reverse shoulder arthroplasty was 79%. The mean level of sports at the time of the survey was worsened in 7.9%, improved in 39.6% and had no change in 55.2% of the cases.Conclusions and relevanceBased on the current available data, return to sports after reverse shoulder arthroplasty is possible and highly frequent. The subjective level of practice undergoes no change or improves in most of the cases. More studies and better-designed trials are needed in order to enrich the evidence on specific sports recovery after the procedure.Level of evidenceIV.

Floor and ceiling effects in the Oxford Shoulder Score

Aims The main objective of this study was to examine whether the Oxford Shoulder Score (OSS) demonstrated floor or ceiling effects when used to measure outcomes following shoulder arthroplasty in a large national cohort. Secondary objectives were to assess its pain and function subscales, and to identify independent predictors for patients achieving a postoperative ceiling score following shoulder arthroplasty. Methods Secondary database analysis of the National Joint Registry (NJR), which included 48,270 patients undergoing shoulder arthroplasty, was conducted. The primary outcome measure was the OSS. Secondary outcome measures were the OSS-Function Component Subscale and OSS-Pain Component Subscale. Floor and ceiling effects were considered to be present if > 15% of patients scored either the lowest or highest possible score. Logistic regression analysis was used to identify independent predictors for scoring the highest possible OSS score postoperatively. Results Preoperatively, 1% of patients achieved the lowest possible OSS score (0) and 0.4% of patients achieved the highest possible score (48). Postoperatively, < 1% of patients achieved the lowest score at all timepoints, but the percentage achieving the highest score at six months was 8.3%, at three years 16.9%, and at five years 17%. Male patients, those aged between 60 and 89 years, and those undergoing an anatomical total shoulder arthroplasty (ATSA) were more likely to contribute to the ceiling effect seen in the OSS questionnaire. Pain and function subscales exhibited greater ceiling effects at three years and five years when compared with the overall OSS questionnaire. Logistic regression analysis showed that sex, procedure type, and preoperative OSS score were independent predictors for scoring the highest possible OSS at years. Conclusion Based on NJR patient-reported outcome measures data, the OSS does not exhibit a ceiling effect at six months, but does at three years and five years, in part due to outcome scores of ATSA. Preoperative OSS, age, male sex, and ATSA are independent predictors of achieving a ceiling score. Cite this article: Bone Joint J 2021;103-B(11):1717–1724.

Development and assessment of 3-dimensional computed tomography measures of proximal humeral bone density: a comparison to established 2-dimensional measures and intraoperative findings in patients undergoing shoulder arthroplasty.

BackgroundThe purpose of this study was to develop novel three-dimensional (3D) measures of bone density from computed tomography (CT) scans and to compare them with validated two-dimensional (2D) radiographic assessments of bone density. Patient demographic data were also analyzed to see if there were any predictors of bone density (age, sex, etiology).MethodsThe study group consisted of 290 consecutive patients undergoing primary shoulder arthroplasty surgery (total anatomic, reverse, and hemiarthroplasty). All underwent preoperative CT imaging. Three 3D CT measurements (metaphysis cancellous, metaphysis cortical, and proximal diaphysis) were developed and automated into software. The developed 3D measurements were compared with validated 2D measures (Tingart and Gianotti Index). Patient demographic data were correlated with these measurements. The difference between the size of the final sounder and of the final stem was calculated as Delta.ResultsThere was moderately strong correlation between Tingart and Gianotti measures (0.674, P < .001), as well as between 3D metaphysis cancellous measurements and Tingart (0.645, P < .001). Decreased bone density was highly correlated with female sex. Tingart (area under the curve [AUC]: 0.87, 95% confidence interval [CI]: 0.82-0.91) and 3D metaphysis cancellous (AUC: 0.78, 95% CI: 0.72-0.84) had the highest correlation. These were significantly more than other measures of bone density (P < .01). Decreased bone density measured with Tingart also had moderate correlation with advanced age (AUC: 0.67, 95% CI: 0.6-0.73), but less so for etiology (AUC: 0.62, 95% CI: 0.55-0.69). The 3D metaphysis cancellous measure had lower correlation with age (AUC: 0.59, 95% CI: 0.52-0.66) and etiology (AUC: 0.59, 95% CI: 0.52-0.65). The highest correlation with Delta (the difference between the final sounder and the stem size) was with the 3D metaphysis cancellous measure (AUC: 0.67, 95% CI: 0.59-0.73), followed by Tingart (AUC: 0.647, 95% CI: 0.57-0.671). A multiple regression model to predict Delta demonstrated the stronger prediction using 3D metaphysis cancellous (analysis of variance F-ratio of 42.6, P < .001) than Tingart (35.9, P < .001).ConclusionThis study demonstrates that automated measures of bone density can be obtained from 3D CT scans. Of the three novel 3D measurements of bone density, the humeral metaphysis cancellous measurement was most correlated to the known 2D measures and most correlated to the intraoperative assessment of bone density (delta).

Significant variability exists in preoperative planning software measures of glenoid morphology for shoulder arthroplasty

Background & HypothesisWe sought to assess the reliability of 4 different shoulder arthroplasty 3-dimensional preoperative planning programs. Comparison was also made to manual measurements conducted by 2 fellowship-trained musculoskeletal radiologists. We hypothesized that there would be significant variation in measurements of glenoid anatomy affected by glenoid deformity. MethodsA retrospective review of computed tomography (CT) scans of patients undergoing shoulder arthroplasty was undertaken. A total of 76 computed tomographies were analyzed for glenoid version and inclination by 4 templating software systems (VIP, Blueprint, TrueSight, ExactechGPS). Inter-rater reliability was assessed via intra-class correlation coefficient (ICC). For those shoulders with glenohumeral arthritis (58/76), ICC was also calculated when sub-grouping by modified Walch classification. Lin's concordance correlation coefficient was calculated for each system with 2 musculoskeletal-trained radiologists’ measurements. ResultsMeasurements of glenoid version and inclination differed between at least 2 programs by 5º-10º in 75% and 92% of glenoids respectively, and by >10º in 18% and 45% respectively. ICC was excellent for version but only moderate for inclination. ICC was highest among Walch A glenoids for both version (near excellent) and inclination (good), and lowest among Walch D for version (near poor) and Walch B for inclination (moderate). When measuring version, VIP had the highest concordance with manual measurement; Blueprint had the lowest. For inclination Blueprint had the highest concordance; ExactechGPS had the lowest. Discussion & ConclusionDespite overall high reliability for measures of glenoid version between 4 frequently utilized shoulder arthroplasty templating softwares, this reliability is significantly affected by glenoid deformity. The programs were overall less reliable when measuring inclination, and a similar trend of decreasing reliability with increasing glenoid deformity emerged that was not statistically significant. Concordance with manual measurement is also variable. Further research is needed to understand how this variability should be accounted for during shoulder arthroplasty preoperative planning. Level of EvidenceLevel III; Retrospective Comparative Study

Congestive heart failure and renal failure in total shoulder arthroplasty: a national database study

BackgroundCongestive heart failure and renal failure are volume sensitive pathologies that lead to significant morbidity and mortality. Due to the aging population in the United States, more patients with volume sensitivity are expected to undergo shoulder arthroplasty. The purpose of this study was to determine the effect of volume sensitive comorbidities on acute postoperative outcomes following shoulder arthroplasty. MethodsThe American College of Surgeons National Surgical Quality Improvement Program was used to identify patients who underwent primary elective shoulder arthroplasty from January 1, 2011 to December 31, 2018. Patients who were diagnosed with volume sensitive diseases (congestive heart failure, kidney failure, and dialysis) were compared with non-volume sensitive patients. Demographic data, length of hospital stay, and postoperative complications within 30 days were analyzed. Multivariable logistic regression was used isolate the effect of volume sensitivity on postoperative complications and readmission. ResultsA total of 23,761 patients underwent shoulder arthroplasty and 218 (0.9%) were volume sensitive. The overall adverse event rate across all patients was 6.5%. On univariate analysis, volume sensitive patients were more likely to need a reoperation within 30 days, require readmission within 30 days, have a minor or major complication, and were less likely to be discharged home (P < .05). However, multivariable logistic analysis found that volume sensitive comorbidities were not independently associated with readmission or major complications. Increasing age and higher ASA classification were associated with increased odds of both major and minor complications, and reduced odds of discharge home ConclusionThere is an increased rate of adverse acute outcomes following shoulder arthroplasty in the volume sensitive population which may be a result of comorbid factors, such as dependent functional status, increasing age, and higher ASA classification. Level of EvidenceLevel III; Retrospective Case-Control Study

Candidacy for ambulatory outpatient shoulder arthroplasty: a retrospective review

BackgroundOutpatient shoulder arthroplasty performed in an ambulatory surgery center has been shown to be a safe and cost-effective practice in appropriately selected patients. The decision to proceed with outpatient shoulder arthroplasty is based on a multitude of factors, including the patient's overall medical status, insurance type, social factors, and complexity of shoulder pathology. Currently, there is a paucity of literature that exists identifying the main drivers in determining in which setting, outpatient or inpatient, shoulder arthroplasty is performed. MethodsA retrospective chart review of 1017 patients who underwent total shoulder arthroplasty (TSA) or reverse total shoulder arthroplasty at a single institution between January 2014 and February 2020 was performed. Each patient was screened for medical candidacy using a previously described evidenced-based patient selection algorithm based on age and cardiopulmonary risk factors. Clinical documentation and billing records were reviewed to determine the setting in which the shoulder arthroplasty was performed and the primary factors for determining inpatient shoulder arthroplasty. ResultsOverall 837 (82.3%) arthroplasties were performed inpatient, with at least a 23-hour hospital stay, and 180 (17.7%) were performed outpatient at a free-standing ambulatory orthopedic surgery center. The patient selection algorithm identified 522 (51.3%) patients as medical candidates for outpatient surgery. Poor candidacy based on medical risk stratification (495; 59.1%) and government insurance payors (231; 27.6%) were the most common reasons for a procedure to be performed in an inpatient setting. Among those deemed appropriate outpatient candidates but who had surgery in an inpatient setting, insurance status (231; 67.5%) was the most common reason, whereas additional medical or social concerns represented a smaller proportion (40; 11.7%). Eliminating shoulder arthroplasty as an inpatient-only code would have effectively transitioned 231 patients, 22.7% of the entire cohort, from an inpatient setting to an outpatient setting. ConclusionsMedical stratification and insurance status both contribute significantly toward the decision to perform shoulder arthroplasty outpatient. Should policy change occur that eliminates shoulder arthroplasty from the Centers for Medicare and Medicaid Services inpatient-only distinction, a significant increase in outpatient shoulder arthroplasty volume would be expected. In the absence of insurance requirements, our data suggest that 40.4% of patients could safely undergo shoulder arthroplasty in an outpatient setting. Level of EvidenceLevel III, retrospective comparative study.

A Three-Dimensional CT Technique to Assess Early Implant Migration and Radiolucency Lines in Total Shoulder Arthroplasty

The aim of this study is to investigate if a new CT based method could be used to assess early migration and follow the development of radiolucency lines over time in a cohort of patients that underwent shoulder arthroplasty.

Surgical Complications After Reverse Total Shoulder Arthroplasty and Total Shoulder Arthroplasty in the United States

Introduction:Shoulder arthroplasty has become popular in the treatment of degenerative shoulder conditions in the United States. Shoulder arthroplasty usage has expanded to younger patients with increased surgical indications.Methods:Reverse total shoulder arthroplasty (RTSA) and TSA patient records with the 1-year follow-up between 2015 and 2018 were queried from the nationwide PearlDiver Mariner Shoulder Database using International Classification of Disease-10 codes. Chi-square analysis was done to compare the demographics, surgical complications, and revision procedures between RTSA and TSA.Results:From 2010 to 2018, there was an increase in shoulder arthroplasty cases because of RTSA. The overall surgical complication and revision procedure rates were 2.26% and 3.56% for RTSA, and 6.36% and 2.42% for TSA. Patients older than 50 years had statistically lower surgical complications after RTSA than TSA (2.25% versus 3.94%, P < 0.05), whereas no statistical difference between RTSA and TSA for patients younger than 50 years (10.06% versus 7.45%, P = 0.19). Male patients had higher RTSA complication rates (3.12% versus 2.28%, P < 0.05), whereas female patients had higher TSA (4.86% versus 5.92%, P < 0.05). History of tobacco, depression, and obesity were risk factors for higher complications.Conclusion:RTSA has become more commonly done than TSA in the United States. Older patients who underwent shoulder arthroplasty had lower surgical complication. TSA had a higher surgical complication rate than RTSA for patients older than 50 years.

Primary and revision shoulder arthroplasty in patients with pulmonary hypertension: an underlying condition associated with high perioperative mortality and complications

BackgroundPulmonary hypertension is a progressive medical condition that has been identified as a risk factor for perioperative morbidity and mortality in both cardiac and non-cardiac surgery, including hip arthroplasty. Currently, there is very limited information on the impact of pulmonary hypertension (PHTN) on patients undergoing shoulder arthroplasty. This investigation analyzed the mortality, perioperative medical complications, implant survivorship, and clinical outcomes in this medically complex cohort. MethodsBetween January 2000 and July 2018, 380 primary and 59 revision shoulder arthroplasties were performed at a single institution in patients with a diagnosis of pulmonary hypertension prior surgery. Average age was 72.8 ± 11.0 and 72.1 ± 9.5 years for the primary and revision SA groups, respectively (P= .65). The median American Society of Anesthesiologists (ASA) scores were predominantly class 3 in both cohorts. Descriptions of group characteristics were calculated with student tests for numerical values. Mortality after primary and revision shoulder arthroplasties were individually calculated through a cumulative incidence analysis. Implant survivorship was analyzed with a competing risk model selecting death as the competing risk. ResultsThe 90-day mortality was 1.6% for primary and 3.4% for revision SA, respectively. The cumulative incidences of death at 2, 5, 10, and 15 years were 16.5%, 43.3%, 80.8%, and 88.5% for primary and 12.1%, 44.7%, 64.4%, and 100% for revision arthroplasties, respectively. Medical complications were observed in 13.4% of primary and 42.4% of revision shoulder arthroplasties. These included respiratory failure and/or acute respiratory distress syndrome (3.2%), arrhythmia (2.7%), deep vein thrombosis (1.8%), and pulmonary embolism (1.6%). The 10-year cumulative incidences of revision for any reason were 4.5% in primary and 10.4% in revision shoulder arthroplasties. At final follow-up, the mean VAS and ASES scores were 2.3 ± 2.5 and 72.0 ± 18.5 in primary SA and 4.1 ± 2.9 and 51.8 ± 21.8 in revision SA. ConclusionsA concomitant diagnosis of PHTN in patients undergoing primary or revision shoulder arthroplasty was associated with a high rate of perioperative medical complications and mortality rates at 90 days and at 10 years in both cohorts. This information should be considered to counsel patients, optimize their perioperative management, and anticipate a more complicated and costly postoperative recovery. Level of EvidenceLevel IV; Case Series with no Comparison Group

Return to Golf Following Reverse Total Shoulder Arthroplasty.

The object of this study was to examine return to golf and changes in golf performance after shoulder arthroplasty. Additionally, we set out to determine if there were differences in return to play and performance between total shoulder arthroplasty (TSA) and reverse total shoulder arthroplasty (RTSA). We also examined pain during the golf swing to determine if there is a change in pain level after surgery. Patients were identified using a Current Procedural Terminology code 23472 search for TSA. A 19-question online survey was sent out to each patient with questions detailing golfing performance and pain during the swing before and after surgery. Comparisons were made to determine differences in pain, performance and enjoyment between TSA and RTSA groups before and after surgery. A total of 586 patients who underwent shoulder arthroplasty were sent the online survey via email. Of those patients, 33 identified themselves as golfers and who responded to the survey, resulting in an overall response rate of 5.6%. Twenty-three of 31 (74%) patients were able to return to golf following their procedure. Overall, the respondents who reported pain associated with golfing activity had significantly decreased pain after undergoing either TSA or RTSA. The RTSA group had a significant drop in driving distance following the procedure and this was significantly lower than the postoperative driving distance in the TSA group, despite an insignificant preoperative difference. Overall, TSA offers a safe and effective means for reducing pain during the golf swing in patients suffering from advanced shoulder osteoarthritis. While there were no significant changes in performance following TSA, individuals undergoing RTSA can be counseled that they are at risk for lower driving distances due to altered mechanics. Overall, patients were satisfied with their procedure and their ability to return to the golf course.

Chronic Kidney Disease Is Associated with High Mortality Risk in Patients with Diabetes after Primary Shoulder Arthroplasty: A Nationwide Population-Based Cohort Study.

The number of diabetic patients with chronic kidney disease (CKD) undergoing shoulder arthroplasty is growing. This study aims to compare perioperative outcomes of shoulder arthroplasty in diabetic patients at different renal function stages. Between 1998 and 2013, a total of 4443 diabetic patients with shoulder arthroplasty were enrolled: 1174 (26%) had CKD without dialysis (CKD group), 427 (9%) underwent dialysis (dialysis group), and 3042 (68%) had no CKD (non-CKD group). Compared with the non-CKD group, the CKD (odds ratio [OR], 4.69; 95% confidence interval [CI], 2.02–10.89) and dialysis (OR, 6.71; 95% CI, 1.63–27.73) groups had a high risk of in-hospital death. The dialysis group had a high risk of infection after shoulder arthroplasty compared with the CKD (subdistribution hazard ratio [SHR], 1.69; 95% CI, 1.07–2.69) and non-CKD (SHR, 1.76; 95% CI, 1.14–2.73) groups. The dialysis group showed higher risks of all-cause readmission and mortality than the CKD and non-CKD groups after a 3-month follow-up. In conclusion, CKD was associated with worse outcomes after shoulder arthroplasty. Compared with those without CKD, CKD patients had significantly increased readmission and mortality risks but did not have an increased risk of surgical complications, including superficial infection or implant removal.

The impact of Charlson and Elixhauser comorbidities on patient outcomes following shoulder arthroplasty.

To investigate the impact of the Charlson and Elixhauser comorbidity indices on patient-reported outcomes measures (PROMs) following shoulder arthroplasty. Patients undergoing total shoulder arthroplasty (TSA), reverse shoulder arthroplasty (RSA), or hemiarthroplasty (HA) from 2016 to 2018 were identified, along with the Charlson and Elixhauser comorbidities listed as their secondary diagnoses in the electronic medical records. Patients were matched to our institution's registry to obtain their PROMs, including shoulder-specific (American Shoulder and Elbow Society (ASES) and Shoulder Activity Scale (SAS)) and general health scales (12-Item Short Form Survey (SF-12) and Patient-Reported Outcomes Measurement Information System-Pain Interference). Linear regression models adjusting for age and sex were used to evaluate the association between increasing number of comorbidities and PROM scores. A total of 1,817 shoulder arthroplasties were performed: 1,017 (56%) TSA, 726 (40%) RSA, and 74 (4%) HA. The mean age was 67 years (SD 10), and 936 (52%) of the patients were female. The most common comorbidities were obesity (1,256, 69%) and hypertension (990, 55%). Patients with more comorbidities had lower ASES and SAS scores at baseline (p < 0.001). Elixhauser comorbidities continued to negatively impact ASES and SAS scores at one year (p = 0.002) and two-year follow-up (p = 0.002). Patients with more comorbidities reported greater pain interference on PROMIS at baseline (p = 0.007), but not at two years. Higher number of Charlson comorbidities were associated with lower scores on the SF-12 mental component at baseline (p < 0.001) and two years (p = 0.020). Higher number of Elixhauser comorbidities were associated with lower SF-12 physical component scores at baseline (p < 0.001) and two years (p = 0.004). Higher number of comorbidities was associated with lower baseline scores and worse outcomes on both shoulder-specific and general health PROMs. The presence of specific comorbidities may be used during shared decision-making to manage expectations for patients undergoing shoulder arthroplasty. Cite this article: Bone Joint J2021;103-B(5):964-970.

Automated Nerve Monitoring in Shoulder Arthroplasty: A Prospective Randomized Controlled Study.

Evoked potential monitoring is believed to prevent neurologic injury in various surgical settings; however, its clinical effect has not been scrutinized. It was hypothesized that an automated nerve monitor can minimize intraoperative nerve injury and thereby improve clinical outcomes in patients undergoing shoulder arthroplasty. A prospective, blinded, parallel group, superiority design, single-center, randomized controlled study was conducted. Study participants were equally randomized into either the automated nerve-monitored or the blinded monitored groups. The primary outcome was intraoperative nerve injury burden as assessed by the cumulative duration of nerve alerts. Secondary outcomes were neurologic deficits and functional scores of the operative arm, and the quality of life index (Euro Quality of life-5 domain-5 level score) at postoperative weeks 2, 6, and 12. From September 2018 to July 2019, 213 patients were screened, of whom 200 were randomized. There was no statistically significant difference in the duration of nerve alerts between the automated nerve-monitored and control groups (median [25th, 75th interquartile range]: 1 [0, 18] and 5 [0, 26.5]; Hodges-Lehman difference [95% CI]: 0 [0 to 1] min; P = 0.526). There were no statistically significant differences in secondary outcomes between groups. However, in the ancillary analysis, there were reductions in neurologic deficits and improvements in quality of life index occurring in both groups over the course of the study period. Protection from nerve injury is a shared responsibility between surgeons and anesthesiologists. Although a progressive improvement of clinical outcomes were observed over the course of the study in both groups as a consequence of the real-time feedback provided by the automated nerve monitor, this trial did not demonstrate that automated nerve monitoring by itself changes important clinical outcomes compared with no monitoring.

Malnutrition in elective shoulder arthroplasty: a multi-institutional retrospective study of preoperative albumin and adverse outcomes.

Malnutrition is associated with poor postoperative outcomes after knee, hip, and spine surgery. However, whether albumin labs should be part of the routine preoperative workup for shoulder arthroplasty remains understudied. This study investigated the role of preoperative albumin levels in predicting common postoperative adverse outcomes in patients undergoing shoulder arthroplasty. All shoulder arthroplasty cases performed at 2 tertiary referral centers between July 2013 and May 2019 (institution 1) and between June 2007 and Feb 2020 (institution 2) were reviewed. A total of 421 primary and 71 revision elective shoulder arthroplasty cases had preoperative albumin levels recorded. Common demographic variables and relevant Elixhauser comorbidities were pulled. Outcomes gathered included extended (>3 days) postoperative inpatient length of stay (eLOS), 90-day readmission, and discharge to rehab or skilled nursing facility (SNF). The prevalence of malnutrition (albumin <3.5 g/dL) was higher in the revision group compared with the primary group (36.6% vs. 19.5%, P = .001). Reverse shoulder arthroplasty (P = .013) and increasing American Society of Anesthesiologists score (P = .016) were identified as independent risk factors for malnutrition in the primary group. In the revision group, liver disease was associated with malnutrition (P = .046). Malnourished primary shoulder arthroplasty patients had an increased incidence of eLOS (26.8% vs. 13.6%, P = .003) and discharge to rehab/SNF (18.3% vs. 10.3%, P = .045). On univariable analysis, low albumin had an odds ratio (OR) of 2.34 for eLOS (P = .004), which retained significance in a multivariable model including age, American Society of Anesthesiologists score, sex, and body mass index (OR 2.11, P = .03). On univariable analysis, low albumin had an OR of 1.94 for discharge to SNF/rehab (P = .048), but this did not reach significance in the multivariable model. Among revisions, malnourished patients had an increased incidence of eLOS (30.8% vs. 6.7%, P = .014) and discharge to rehab/SNF (26.9% vs. 4.4%, P = .010). In both the primary and revision groups, there was no difference in 90-day readmission rate between patients with low or normal albumin. Malnutrition is more prevalent among revision shoulder arthroplasty patients compared with those undergoing a primary procedure. Primary shoulder arthroplasty patients with low preoperative albumin levels have an increased risk of eLOS and may have an increased need for postacute care. Low albumin was not associated with a risk of 90-day readmissions. Albumin level merits further investigation in large, prospective cohorts to clearly define its role in preoperative risk stratification.

Factors Associated With Elevated Inflammatory Markers Prior to Shoulder Arthroplasty.

Background: Preoperative erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) ranges for several shoulder arthroplasty indications are not well understood. Purpose: We sought to compare preoperative ESR and CRP values for a variety of shoulder arthroplasty indications and evaluate risk factors for elevated preoperative ESR and CRP values. Methods: We conducted a retrospective cohort study of shoulder arthroplasty cases performed at a single academic medical institution from 2013 to 2018. Preoperative ESR and CRP values for 235 shoulder arthroplasties with various indications were recorded. Independent risk factors for elevated values (CRP > 10.0 mg/L and ESR > 30.0 mm/h) were determined via multiple variable logistic regression. Results: Patients undergoing shoulder arthroplasty for osteoarthritis had an ESR (mean ± SD) of 22.6 ± 17.8, with 29.8% of patients elevated, and a CRP of 6.5 ± 6.4, with 25.5% of patients elevated. Arthroplasty for acute fracture and prosthetic joint infection (PJI) had higher preoperative ESR and CRP values. Multivariate analysis identified several predictors of elevated ESR, including infection, acute fracture, diabetes, and female sex. It also identified predictors of elevated CRP, including infection, acute fracture, and younger age. Conclusions: Preoperative ESR and CRP values may be elevated in 25% to 30% of patients undergoing primary shoulder arthroplasty. Arthroplasty for both acute fracture and PJI, along with several other patient factors, was associated with elevated preoperative ESR and CRP. Thus, routine collection of ESR and CRP preoperatively may not be of benefit, as elevated values are common. Further study is warranted.

Equal care for all? Do surgical outcomes in shoulder arthroplasty depend on insurance type?

BackgroundAlthough it has been shown that Medicare populations have a higher overall rate of complications than those with private insurances for large cohort total joint studies, there is limited information comparing patient-reported outcomes (PROs) among private insurance patients. The purpose of this study was to determine the impact of non-Medicaid insurance type on outcomes after shoulder arthroplasty.MethodsThis retrospective case-controlled study included 203 patients who underwent shoulder arthroplasty from 2012 to 2017 by a single surgeon. Preoperative and postoperative PROs were collected and included the Simple Shoulder Test, the American Shoulder and Elbow Surgeons Shoulder Assessment Form, and the Constant Shoulder Score. Patients were categorized into groups based on insurer—preferred provider organization, health maintenance organization, Medicare, and Veterans Affairs Care program—and outcomes were compared between groupsResultsThe 4 insurance provider groups were matched for body mass index, surgery type, and comorbidities (P = .526). Preoperatively, no significant differences in PROs between groups were present except for the Constant Shoulder Score (P = .029). All payer groups significantly improved from preoperative to postoperative PROs (P ≤ .001). At the final follow-up, no significant difference in PROs between groups were seen (American Shoulder and Elbow Surgeons Shoulder mean 75.3 ± 20.9 [P = .757], Simple Shoulder Test of 9.1 ± 2.9 [P = .312], and Constant Shoulder Score of 65.0 ± 15.2 [P = .526]).ConclusionsOur results suggest variations in insurance type did not significantly impact outcomes for our cohort of patients undergoing shoulder arthroplasty. Although variations in patient cohorts exist, patients regardless of insurance type and coverage variations can expect significant improvements in their function and pain after shoulder arthroplasty.

The effect of a statewide COVID-19 shelter-in-place order on shoulder arthroplasty for proximal humerus fracture volume and length of stay

BackgroundAlthough the COVID-19 pandemic has disrupted elective shoulder arthroplasty throughput, traumatic shoulder arthroplasty procedures are less apt to be postponed. We sought to evaluate shoulder arthroplasty utilization for fracture during the COVID-19 pandemic and California's associated shelter-in-place order compared to historical controls. MethodsWe conducted a cohort study with historical controls, identifying patients who underwent shoulder arthroplasty for proximal humerus fracture in California using our integrated electronic health record. The time period of interest was following the implementation of the statewide shelter-in-place order: March 19, 2020-May 31, 2020. This was compared to three historical periods: January 1, 2020-March 18, 2020, March 18, 2019-May 31, 2019, and January 1, 2019-March 18, 2019. Procedure volume, patient characteristics, in-hospital length of stay, and 30-day events (emergency department visit, readmission, infection, pneumonia, and death) were reported. Changes over time were analyzed using linear regression adjusted for usual seasonal and yearly changes and age, sex, comorbidities, and postadmission factors. ResultsSurgical volume dropped from an average of 4.4, 5.2, and 2.6 surgeries per week in the historical time periods, respectively, to 2.4 surgeries per week after shelter-in-place. While no more than 30% of all shoulder arthroplasty procedures performed during any given week were for fracture during the historical time periods, arthroplasties performed for fracture was the overwhelming primary indication immediately after the shelter-in-place order. More patients were discharged the day of surgery (+33.2%, P = .019) after the shelter-in-place order, but we did not observe a change in any of the corresponding 30-day events. ConclusionsThe volume of shoulder arthroplasty for fracture dropped during the time of COVID-19. The reduction in volume could be due to less shoulder trauma due to shelter-in-place or a change in the indications for arthroplasty given the perceived higher risks associated with intubation and surgical care. We noted more patients undergoing shoulder arthroplasty for fracture were safely discharged on the day of surgery, suggesting this may be a safe practice that can be adopted moving forward. Level of EvidenceLevel III; Retrospective Case-control Comparative Study

Outcomes of acute but not delayed reverse total shoulder arthroplasty for proximal humerus fracture are equal to those for rotator cuff arthropathy

BackgroundThe utilization of reverse total shoulder arthroplasty (RTSA) for the treatment of proximal humerus fractures in the elderly is increasing. Recent results support the use of RTSA for this indication over hemiarthroplasty or open reduction internal fixation (ORIF). However, there are limited data on the outcomes of RTSA for fracture or fracture sequelae as compared to RTSA for cuff tear arthropathy (CTA). We hypothesized that patients undergoing RTSA for fracture or fracture sequelae would have worse outcomes compared to patients undergoing RTSA for CTA. MethodsThis was a retrospective analysis of a prospectively collected outcomes database of all patients undergoing shoulder arthroplasty at a single institution between 2008 and 2019. Patients were included if they underwent primary RTSA for a diagnosis of acute fracture, fracture nonunion or malunion, failed hemiarthroplasty or ORIF for proximal humerus fracture, or rotator cuff arthropathy. The primary outcome was American Shoulder and Elbow Surgeons (ASES) score at the most recent follow-up, with minimum 1-year follow-up. Secondary outcomes included range of motion (ROM) at most recent follow-up, patient satisfaction with surgery, and revision or reoperation rates. Analysis of variance was used to compare continuous variables between the groups, while chi-square or Fisher's exact test were used to compare categorical variables. Linear regression analysis was used to perform multivariable analysis. Prosthesis survival rates were calculated using Kaplan-Meier survival analysis. Significance was defined as P< .05. ResultsThere were 287 patients included in the final cohort, including 62 with fracture and 225 with CTA. Sex, diagnosis, increasing patient comorbidities, and diagnosis (malunion/nonunion and failed prior surgery) were associated with worse ASES scores on univariate analysis (P < .05). On multivariate analysis, there was no difference in outcomes (ASES and ROM) between the acute fracture and CTA cohorts (P > .05). Outcomes of delayed RTSA for malunion/nonunion and hemiarthroplasty/ORIF were significantly worse than those for acute fracture/CTA (P < .01). Three-year prosthesis survival was 95% for CTA, 97% for acute fracture, 97% for malunion/nonunion, and 78% for failed prior surgery. ConclusionTreatment of acute proximal humerus fractures with RTSA leads to similar improvements in patient outcomes compared to elective treatment for CTA, but outcomes of delayed RTSA for fracture are considerably worse. These findings provide further guidance to clinicians counselling patients on treatment options and outcomes for proximal humerus fractures. Level of evidenceLevel III; Retrospective comparative study

Predictors of blood transfusion in patients undergoing total shoulder arthroplasty

BackgroundAnatomic total shoulder arthroplasty (TSA) and reverse total shoulder arthroplasty are major surgeries that may result in significant blood loss and the need for transfusion. The purpose of this study was to identify predictors for blood transfusion in patients undergoing TSA. MethodsThe American College of Surgeons National Surgical Quality Improvement Program was used to identify 12,982 patients who underwent TSA (anatomic or reverse) from January 1, 2011 to December 31, 2016. We compared patients who underwent intraoperative or postoperative blood transfusion with those who did not receive a blood transfusion. Multivariable logistic regression was used to determine independent factors associated with blood transfusion. ResultsThe rate of intraoperative and postoperative blood transfusion was 3.5% during the study period. Compared with patients who did not receive a blood transfusion, those who did were older (73.4 vs. 68.9 years, P < .001), had longer operative times (137.8 vs. 110.7 minutes, P < .001), had longer hospital stays (3.9 vs. 1.9 days, P < .001), and were more likely to be female (74% vs. 55%, P < .001). Patients who received a blood transfusion had higher mean American Society of Anesthesiologists (ASA) classification score (2.8 vs. 2.5, P < .001). The following factors were independently associated with greater odds of blood transfusion: ASA class 4 (odds ratio [OR] 8.4, 95% confidence interval [CI] 2.0-36), dialysis (OR 2.5, 95% CI 1.0-5.9), bleeding disorders (OR 2.4, 95% CI 1.6-3.5), female sex (OR 1.8, 95% CI 1.4-2.3), and smoking (OR 1.4, 95% CI 1.0-2.0). Patients with independent functional status before surgery were least likely to require blood transfusion (OR 0.5, P < .001). ConclusionIn patients undergoing shoulder arthroplasty, preoperative factors such as ASA classification, smoking, and functional status can be used to identify patients at increased risk for requiring blood transfusion. Level of evidenceLevel III.

The association between bisphosphonate use and aseptic revision risk in primary elective shoulder arthroplasty

BackgroundThe total joint literature has shown promising results of bisphosphonate use on decreasing early bone loss after hip and knee arthroplasty and reducing aseptic revision risk though a higher risk of periprosthetic fracture has also been reported. We sought to evaluate the association between bisphosphonate use and aseptic revision risk in patients undergoing shoulder arthroplasty. MethodsA US integrated healthcare system's registry was used to identify 6204 patients who underwent primary elective shoulder arthroplasty for osteoarthritis (2005-2016). Preoperative bisphosphonate users (defined as having at ≥6-month supply and 80% adherence) were compared to nonbisphosphonate users. Multivariable Cox proportional hazard regression was used to evaluate aseptic revision risk according to bisphosphonate use while adjusting for confounders. Secondary analysis stratified by age (40-64, ≥65 years) and bone quality status (normal, osteopenia, osteoporosis, or unknown). ResultsAt the time of index procedure, 564 (9.1%) were considered as bisphosphonate users. We failed to observe a difference in aseptic revision risk by bisphosphonate use (hazard ratio = 0.92, 95% confidence interval = 0.50-1.72). No association was observed even after stratifying by bone quality and age. No revisions for periprosthetic fracture occurred in the bisphosphonate user group during follow-up. ConclusionsWhile prior studies in lower extremity joint arthroplasty cohorts have observed a differential risk for revision surgery with bisphosphonate use, we failed to observe any associations between bisphosphonate use and revision risk in a cohort of shoulder arthroplasty patients. Level of EvidenceLevel III; Retrospective Cohort Comparative Study