Underwent Silicone Oil Removal Research Articles

Accuracy of using the axial length of the fellow eye for IOL calculation in retinal detachment eyes undergoing silicone oil removal

PurposeEvaluate whether the axial length of the fellow eye can be used to calculate the intraocular lens (IOL) in eyes with retinal detachment.DesignRetrospective, consecutive case series.MethodsOur study was conducted at...

The Emulsification of Silicone Oil 5000 cs in Patients With Retinal Detachment.

Background The emulsification of silicone oil is a significant concern for those with rhegmatogenous retinal detachment (RRD) following surgery. The aim of the study was to assess the frequency of emulsification in the patients who underwent primary vitrectomy and were administered 5000 cs silicone oil. Methodology The Layton Rahmatullah Benevolent Trust in Lahore conducted an ophthalmology study from January 2022 to March 2023. The patients who had primary vitrectomy for RRD with silicone oil tamponade were included regardless of age or gender. Those on anti-inflammatory or steroid medications prior to surgery were excluded. Retinal attachment was examined 8-12 weeks post operation to assess silicone oil removal eligibility. Emulsification occurrence was reported. Data on emulsification time, visual acuity (pre- and post-removal), mean intraocular pressure (IOP), and clinical outcomes were collected and analyzed using the Statistical Package for Social Sciences (SPSS) software (IBM SPSS Statistics, Armonk, NY). The results were graphically presented with mean, standard deviations, frequencies, and proportions. Results A total of 158 patients underwent silicone oil removal after undergoing primary vitrectomy for RRDwith silicone oil. The mean age of the patients was 45.90 ± 17.8 years. The mean preoperative intraocular pressure (IOP) among the patients was 16.28 ± 2.97 mmHg. Post removal of silicone oil, the IOP was reduced to 12.66 ± 3.02 mmHg. In 11 out of 158 cases (6.9%) of RRD, emulsification had occurred with silicone oil 5000 cs. We found that out of 11 cases of emulsification, eight (72.73%) were 40 years or older in age. Seven (63.64%) patients had tamponade duration of 10 weeks or longer. However, the difference was not statistically significant. Conclusion In conclusion, our study found that the incidence of emulsification of 5000 cs silicone oil in the patients who underwent primary vitrectomy for the treatment of RRD was 6.9%. We observed that emulsification was more frequent in patients aged 40 years or older and those with a tamponade duration of 10 weeks or longer, although the difference was not statistically significant. Further investigation with bigger sample sizes and extended follow-up periods is required to verify our findings and explore potential factors that could lead to emulsification in this group of patients.

Chandelier-assisted pars plana vitrectomy decreases the rate of retinal re-detachment following silicone oil removal

Background Recurrent retinal detachment is one of the major complications after silicone oil (SO) removal. Therefore, finding ways to decrease its incidence would be of great significance. Purpose The aim of this study was to compare the rate of retinal re-detachment following SO removal in eyes that underwent scleral self-indentation during chandelier-assisted vitreous base shaving compared to the eyes that underwent scleral indentation by an assistant. Patients and methods This is a retrospective study that included 381 eyes of 381 consecutive patients who underwent SO removal between December 2017 and December 2021, after a successful pars plana vitrectomy for primary rhegmatogenous retinal detachment. Scleral self-indentation (group A) was performed in 186 eyes, while scleral indentation by an assistant (group B) was performed in 195 eyes. The primary outcome measure was the rate of retinal re-detachment after SO removal. The secondary outcome measures were the rate of iatrogenic peripheral retinal tears and intraoperative complications. Results Retinal re-detachment occurred in 21 (11.29%) eyes in group A compared to 38 (19.49%) eyes in group B, with a statistically significant difference (P=0.027). Iatrogenic retinal tear during vitreous base shaving occurred in two (1.08%) eyes in group A compared with 17 (8.71%) eyes in group B, with a statistically significant difference (P=0.001). Slipped infusion cannula during indentation occurred in two (1.02%) eyes in group B and resulted in serous choroidal detachment in one eye, a complication that was not reported in group A. Lens touch occurred in three (1.61%) eyes in group A versus eight (4.1%) eyes in group B, a statistically nonsignificant difference (P=0.065). Conclusion Scleral self-indentation during chandelier-assisted vitrectomy facilitated safe and satisfactory vitreous base shaving with a lower risk of retinal re-detachment after SO removal. It was also associated with a lower rate of iatrogenic retinal breaks and intraoperative complications.

Early vascular changes after silicone oil removal using optical coherence tomography angiography

BackgroundThis study evaluated the vascular changes in the macular and peripapillary regions before and after silicone oil (SO) removal in patients with rhegmatogenous retinal detachment.MethodsThis single-center case series assessed patients who underwent SO removal at one hospital. Patients who underwent pars plana vitrectomy and perfluoropropane gas tamponade (PPV + C3F8) were selected as controls. Superficial vessel density (SVD) and superficial perfusion density (SPD) in the macular and peripapillary regions were assessed by optical coherence tomography angiography (OCTA). Best-corrected visual acuity (BCVA) was assessed using LogMAR.ResultsFifty eyes were administered SO tamponade, 54 SO tamponade(SOT) contralateral eyes, 29 PPV + C3F8 eyes, and 27 PPV + C3F8 contralateral eyes were selected. SVD and SPD in the macular region were lower in eyes administered SO tamponade compared with SOT contralateral eyes (P < 0.01). Except for the central area, SVD and SPD in the other areas of the peripapillary region were reduced after SO tamponade without SO removal (P < 0.01). No significant differences were found in SVD and SPD between PPV + C3F8 contralateral and PPV + C3F8 eyes. After SO removal, macular SVD and SPD showed significant improvements compared with preoperative values, but no improvements in SVD and SPD were observed in the peripapillary region. BCVA (LogMAR) decreased post-operation and was negatively correlated with macular SVD and SPD.ConclusionsSVD and SPD are decreased during SO tamponade and increased in the macular region of eyes that underwent SO removal, suggesting a possible mechanism for reduced visual acuity during or after SO tamponade.Trial registrationRegistration date: 22/05/2019; Registration number, ChiCTR1900023322; Registration site, Chinese Clinical Trial Registry (ChiCTR).

Persistent hypotony following high-intensity focused ultrasound treatment in a glaucomatous eye

We report the case of a 60-year-old female with primary angle-closure glaucoma, who presented with intraocular pressure (IOP) of 0 mmHg, significant cataract, and finger-counting vision in her left eye (LE) following high-intensity focused ultrasound (HIFU) treatment. She underwent LE cataract surgery combined with pars plana vitrectomy, membrane peeling, and silicon oil injection. Postoperatively, hypotony improved, and visual acuity improved to 20/160. One and a half years later, she underwent silicone oil removal (SOR) in view of recovered ciliary secretion and elevated IOP. Post-SOR, IOP remained elevated due to complete synechial closure secondary to prolonged hypotony and the patient is awaiting an incisional surgery. This case highlights the serious vision-threatening complications of persistent hypotony following HIFU treatment. We caution the surgeons regarding the use of HIFU in eyes with good visual potential and discuss the importance of understanding the safety and efficacy of a cycloablative procedure.

Intraocular Lens Calculation Using 8 Formulas in Silicone Oil–Filled Eyes Undergoing Silicone Oil Removal and Phacoemulsification After Retinal Detachment

To evaluate formulas for intraocular lens (IOL) calculation in silicone oil (SO)-filled eyes. Retrospective, consecutive case series. We conducted our study at the Department of Ophthalmology, Goethe University, Frankfurt, Germany, and included SO-filled eyes that received SO removal combined with phacoemulsification and IOL implantation. Preoperative assessments included biometry (IOLMaster 700; Carl Zeiss Meditec). To evaluate the measurements, we compared the mean prediction error, and mean and median absolute prediction error of 8 different formulas. A total of 90 eyes matched our inclusion criteria. The median absolute error was lowest in the Barrett Universal II formula (0.43 diopters [D] ± 0.75) followed by Kane (0.44 D ± 0.75), Hill-radial basis function (0.47 D ± 0.74), Holladay II (0.47 D ± 0.77), Sanders Retzlaff Kraff/theoretical (0.51 D ± 0.74), Holladay I (0.51 D ± 0.76), and Haigis and Hoffer Q (0.52 D ± 0.74 each). Regarding eyes within ±0.5 D Barrett Universal II (57.8%, 52 eyes) performed best, again followed by Kane (56.7%, 51 eyes) and Hill-radial basis function (54.4%, 49 eyes). Using modern formulas for IOL calculation in oil-filled eyes improves predictability but still not as good as in unoperated eyes. This issue is created by the change in refractive index due to the SO fill and therefore a lower precision of axial length measurement and effective lens position prediction.

Comparison of axial length measurements in silicone oil-filled eyes using SS-OCT and partial coherence interferometry.

To compare axial length (AL) measurements in silicone oil (SO)-filled eyes using swept-source optical coherence tomography (SS-OCT) (the IOLMaster 700 and OA2000) and partial coherence interferometry (the IOLMaster 500). Zhongshan Ophthalmic Center, Guangzhou, China. Cross-sectional study. We enrolled phakic patients who underwent SO removal surgery. The AL measurements by the IOLMaster 500, IOLMaster 700, and OA2000, both before and after SO removal, were compared. Multiple regression analysis was performed to identify risk factors for the differences between preoperative and postoperative AL measurements. 68 patients (68 eyes) with a mean age of 46.43 ± 13.24 years were included. No statistically significant difference was observed in the preoperative AL measurements between the IOLMaster 500 and IOLMaster 700 (25.48 ± 2.51 mm vs 25.49 ± 2.46 mm; P = .63), whereas the OA2000 yielded shorter AL (25.34 ± 2.36 mm) (both P < .001). After SO removal, the AL measurements showed no statistically significant differences among the 3 devices. In reference to the postoperative AL, the IOLMaster 500 and IOLMaster 700 tended to overestimate the AL in SO-filled eyes (both P < .001), and this measurement error increased with longer AL (β = 0.08 and 0.05, respectively; both P < .001). No statistically significant difference was observed between preoperative and postoperative AL measurements by the OA2000 ( P = .18). The OA2000 is the preferred biometer for AL measurement in SO-filled eyes, whereas the IOLMaster 500 and IOLMaster 700 overestimate the AL especially for long eyes, which needs adjustment in clinical use.

Clinical Study of Intraocular Lens Implantation by Scleral Suture Fixation after Lensectomy and Vitrectomy

Objective: To investigate the surgical techniques and clinical significance of intraocular lens implantation by scleral suture fixation after lensectomy and vitrectomy. Methods: According to the inclusion and exclusion criteria, 19 cases (20 eyes) were selected for IOL implantation by scleral suture fixation after lensectomy and vitrectomy. The uncorrected visual acuity (VA), best-corrected visual acuity (BCVA), intraocular pressure (IOP), preoperative IOL position and surface clarity, and complications were recorded, analyzed and compared. Results: In 20 eyes of 19 patients who underwent IOL implantation by scleral suture fixation in this study, both VA and BCVA after surgeries were significantly improved compared with those before surgeries (P&lt;0.05). 11 eyes of 10 patients had IOP ≥ 21mmHg before surgeries. Three months after surgeries, IOP of all these affected eyes were within 21 mmHg, and no affected eyes required the application of ocular hypotensive drugs. Three months after surgeries, 17 eyes of 16 patients (85%) had centered IOL position and 3 eyes of 3 patients (15%) had slightly tilted IOL, all of these tilted IOLs were in patients with ocular trauma and all of them were found to be caused by scar adhesion in the peripheral part. In two eyes, the IOL optical edge was completely blocked by the pupil, which was only found after dilating the pupil. The pupil of one eye was traumatic and irregularly dilated, and the edge of the optical part of IOL was exposed. In two eyes of two patients who underwent silicone oil removal and IOL fixation during the same surgery, a small number of silicone oil droplets were found on the surface of IOL in the early stage after surgeries, and in the later stage, small flakes of pigment granules were observed. During the 3-month postoperative follow-up period, no patient had complications such as IOL dislocation, exposure of fixation suture, retinal detachment and corneal endothelial decompensation. Conclusion: For patients ....

Accuracy of segmented measurement of axial length in ultra-high myopia filled with silicone oil using immersion B-scan ultrasonography.

To evaluate the accuracy of segmented measurement of axial length (AL) in high myopia filled with silicone oil by immersion B-scan ultrasonography (immersion B-scan). From June 2016 to June 2020, a total of 67 ultra-high myopia inpatients (67 eyes) who underwent silicone oil removal combined with cataract extraction and intraocular lens (IOL) implantation were retrospectively enrolled. The preoperative axial length (AL) of 31 patients with severe cataract were segmented measured using immersion B-scan (B-scan group) and another 36 patients with mild or moderate cataract were measured using IOLMaster 500 (IOLMaster group). The post-operative ALs in two groups were both measured using IOLMaster 500. The IOL power was calculated with Haigis formula. The differences in ALs between pre- and post-surgery, as well as the postoperative refractive spherical equivalent, absolute refractive error, the prediction deviation of postoperative refraction and best corrected visual acuity (BCVA) were compared. The pre- and post-operative ALs were 30.46±1.63 mm (range 28.09-33.51 mm) and 30.42±1.70 mm (range 28.03-33.90 mm) in B-scan group (t=0.644, P=0.542) and 30.51±1.21 mm (range 28.03-33.90 mm) and 30.43±1.27mm (range 28.54-33.50 mm) in IOLMaster group (t=1.843, P=0.074), respectively. Three months after surgery, BCVA were 0.45±0.13 (range 0.3-0.9) and 0.44±0.20 (range 0.2-1.0) in B-scan and IOLMaster group respectively (t=0.086, P=0.932). There was no significant difference of the postoperative spherical equivalent (-3.11±0.65 D vs -3.21±0.51 D, t=0.671, P=0.505) and the absolute refractive error (0.589±0.340 vs 0.470±0.245 D, t=1.615, P=0.112) between two groups. In B-scan group, absolute refractive error within ±0.50 D was found in 18 eyes (58.1%), within ±1.00 D in 26 eyes (83.9%), and within ±1.50 D in 31 eyes (100%). In IOLMaster group, absolute refractive error within ±0.50 D was found in 23 eyes (63.9%), within ±1.00 D in 34 eyes (94.4%), and within ±1.50 D in 36 eyes (Z=0.757, P=0.449). The segmented measurement of ALs by immersion B-scan shows comparable measurement accuracy with that of IOLMaster 500 in ultra-high myopia patients with severe cataract secondary to silicone oil filling and can obtain an ideal postoperative refractive state.

New technique for removal of perfluorocarbon liquid related sticky silicone oil and literature review.

To investigate the safety and efficacy of sticky silicone oil (SSO) removal using a 22-gauge vein detained needle and inner limiting membrane (ILM) wrap-and-peel technique. This retrospective consecutive case series reviewed the records of patients with a history of retinal detachment who had received silicone oil and perfluorocarbon liquid (PFCL) as intraocular tamponades. Patients were included in the analysis if they exhibited SSO remnants during silicone oil removal. The aspiration of most of the SSO remnants was performed by a 22-gauge vein detained needle. The small amounts of droplets adhered to the macula and epi-macular membrane were subsequently removed by the ILM warp-and-peel technique. The anatomical and functional outcomes, and postoperative complications were recorded. In vitro experiments were performed to simulate the formation of SSO remnants in four groups. Of 711 patients who underwent silicone oil removal during the study period, 9 patients exhibited SSO remnants and underwent follow-up for at least 3mo. Seven eyes (78%) underwent the ILM wrap-and-peel technique to completely remove small droplets of SSO that were glued to the macula and epi-macular membrane. No obvious complications occurred. Postoperative optical coherence tomography revealed normal retinal structure in all patients. In vitro analyses showed that balanced salt solution and prolonged vibration (for 1wk) had the strongest effects on silicone oil and PFCL compound opacities. SSO remnants could be removed in an intact manner and without complications, using a vein detained needle-assisted and ILM wrap-and-peel technique. The findings suggest that PFCL and infusion fluid should be completely removed before silicone oil injection to prevent SSO formation.

Status of corneal endothelial cells in the presence of silicone oil in the anterior chamber

To evaluate corneal endothelium damage with silicone oil (SO) presence in the anterior chamber after pars plana vitrectomy. We investigated the medical records of consecutive 54 eyes of 53 patients undergoing SO removal after pars plana vitrectomy with SO tamponade at Saitama Medical Center, Jichi Medical University, Japan. We recorded SO tamponade retention period, anterior chamber SO with gonioscope, area of SO attachment to the corneal endothelium before SO removal surgery, and the lens status. We then retrospectively investigated the correlation between SO presence in the anterior chamber and the decrease rate of corneal endothelial cell (CEC) density during SO tamponade. The average decrease rate of CEC density was 7.6 (0–38.1) %. The correlation between SO tamponade retention period and decrease rate of CEC density was high (p = 0.0001). However, there was no correlation between anterior chamber SO under gonioscope, SO attaching area, and lens status with the decrease rate of CEC density (p = 0.11, p = 0.93, p = 0.16). No correlation was observed between CEC loss and the existence of anterior chamber SO, although CEC decrease rate was relatively high after a long SO tamponade period. These findings suggest that SO presence in the anterior chamber may not directly injure CEC.

Posttraumatic Bacillus cereus Endophthalmitis: Clinical Characteristics and Antibiotic Susceptibilities.

Purpose To report the clinical characteristics, antibiotic susceptibilities, and visual outcomes of patients with posttraumatic endophthalmitis caused by Bacillus cereus. Methods In this retrospective, noncomparative case series, the medical records of eyes with culture-proven Bacillus cereus endophthalmitis treated from January 2016 to December 2019 at a referral center were reviewed. Clinical features, antibiotic susceptibilities, and visual outcomes were assessed. Results A total of 19 eyes of 19 patients were identified. Three patients progressed to orbital cellulitis. Vitrectomy was performed in 13 eyes, and 11 required silicone oil tamponade. Finally, seven eyes underwent silicone oil removal surgery during follow-up. Only two patients retained a visual acuity better than FC. Four patients underwent evisceration, and three patients had NLP. The cultured Bacillus cereus was sensitive to levofloxacin, ofloxacin, tobramycin, and neomycin at 100%. Conclusions The visual outcomes of posttraumatic Bacillus cereus endophthalmitis were generally poor regardless of the prophylactic and therapeutic measures administered. Vitrectomy combined with silicone oil tamponade could help to save the eyeball. Bacillus cereus has a good susceptibility to ofloxacin, levofloxacin, tobramycin, and neomycin; therefore, fluoroquinolones and aminoglycosides can be used to treat Bacillus cereus infection.

PREOPERATIVE AND POSTOPERATIVE MACULAR SENSITIVITY ASSESSMENT USING MICROPERIMETRY IN EYES UNDERGOING SILICONE OIL REMOVAL

To evaluate the functional changes on the macula, before and after silicone oil removal (SOR) using microperimetry (MP3) in patients originally operated for macula-off rhegmatogenous retinal detachments. Prospective interventional study, N = 20. All cases underwent complete ophthalmic examination, including determination of Snellen best-corrected visual acuity, indirect ophthalmoscopy, and MP3 for measuring retinal sensitivity. Primary outcome measure was to describe the alterations in the retinal sensitivity on the macula after SOR. Mean retinal sensitivity increased in 100% patients (20/20) after SOR with a mean value of 97.44 dB. Best-corrected visual acuity after SOR remained unchanged in 90% (18/20) and improved by 2 lines in only 10% patients (2/20). Median retinal sensitivity of central 6° of the macula was 766.95 ± 173.29 dB before SOR and 863.8 ± 181.08 dB after SOR, P < 0.0001. Mean best-corrected visual acuity was 20/40 before SOR (range, 20/30-20/60) (logarithm of the minimum angle of resolution 0.314 ± 0.169) and 20/40 after SOR (range 20/30-20/80) (logarithm of the minimum angle of resolution 0.315 ± 0.159), P = 0.1628. MP3 was found to be a highly sensitive tool in detecting increased retinal sensitivity after SOR, particularly in central 6° of the macula without significant change in best-corrected visual acuity. Hence, MP3 is an important qualitative indicator of visual function.

Silicone oil removal after extended tamponade in proliferative diabetic retinopathy-a long range of follow-up.

To investigate the anatomical and functional results of silicone oil (SO) removal after an extended period of SO tamponade in eyes having received vitrectomy for proliferative diabetic retinopathy (PDR). From May 2009 to August 2017, clinical records of patients who had vitrectomy for PDR and underwent SO removal were retrospectively reviewed. SO was in principle left in the eye for an extended period of time and would be removed promptly when complications relevant to SO rose, or at the same setting when other intraocular surgeries were performed. Main outcome measures include anatomical outcome, functional outcome, and postoperative complications. Seventy-four eyes of 64 patients (31 males and 33 females) were analysed. The mean follow-up duration was 35.6 months (ranging from 6 to 99 months, median 32 months). The duration of SO tamponade ranged from 3 to 116 months (mean 26.89 months, median 16 months). Anatomical success was achieved in 95.9% at the last follow-up with best-corrected visual acuity (BCVA) becoming better or unchanged in 81.1%. Postoperative complications included ocular hypertension (>25 mmHg; > 4 weeks) in three eyes (4.1%), macular hole in two eyes (2.7%), transient choroidal detachment in one eye (1.4%), vitreous haemorrhage in four eyes (5.4%) and hyphaema in two eyes (2.7%). The rate of retinal redetachment after an extended period of SO tamponade and removal was low and the majority of eyes obtained final visual acuity improvement. SO removal after an extended period of tamponade in PDR seems to be safe under proper indications and case selection.

Evaluation of choroidal structural changes after silicone oil removal in rhegmatogenous retinal detachment

Aim: To evaluate the choroidal structural changes after silicone oil (SiO) removal in patients who underwent pars plana vitrectomy (PPV) for macula off rhegmatogenous retinal detachment (RRD).Material and Methods: In this retrospective study, the charts of patients with macula off RRD who underwent SiO removal between February and June 2019 were reviewed. The subfoveal choroidal thickness (SFCT) was measured before and after SiO removal by enhanced depth imaging optical coherence tomography (EDI OCT). The subfoveal choroidal area was (TCA) segmented into luminal (LA) and interstitial stromal area (SA) by the binarization technique using ImageJ software (Version 1.52i, National Institutes of Health, Bethesda, MD USA). Choroidal vascularity index (CVI) was defined as the ratio of LA to the TCA. Results: There were 15 (%62.5) male and 9 (%37.5) female patients in the study group. The mean SFCT was 288.71±63.63 µm under SiO in the operated eyes. After SiO removal the mean SFCT significantly decreased to 259.33±51.25 µm at month 3 (p=0.004). The mean CVI was 63.37±3.50% under SiO filled eyes. After SiO removal, the mean CVI significantly decreased to 58.83±3.41% at month 3 (p0.001). The mean LA was 1.37±0.46 vs. 1.18±0.47 preoperatively and postoperatively in the operated eyes (p=0.028). There was no significant difference in the mean SA and TCA values between preoperative and postoperative measurements (p=0.742, p=0.175, respectively). Conclusion: Image binarization of EDI OCT scans and CVI analysis enables the assessment of choroidal changes after SiO removal. CVI decreased and the lumens of the choroidal vessels became smaller after SiO removal. CVI may be used as a parameter to monitor the choroidal changes that might be associated with inflammation secondary to SiO.

Safety and efficacy of transpupillary silicone oil removal in combination with micro-incision phacoemulsification cataract surgery: comparison with 23-gauge approach

BackgroundTo evaluate safety and efficacy of transpupillary silicone oil removal combined with micro-incision phacoemulsification cataract surgery, and to compare results of transpupillary with 23-gauge three-port vitrectomy approach.MethodsConsecutive cases that underwent silicone oil removal using either transpupillary or three-port approach in combination with micro-incision phacoemulsification cataract surgery were retrospectively reviewed. The main outcome measures were postoperative detachment rate, silicone oil residuals, best corrected visual acuity (BCVA) and intraocular pressure (IOP).ResultsA total of 64 cases were included, 19 in transpupillary and 45 in three-port. Postoperative detachment rate within 3 months in transpupillary versus three-port was 15.8% versus 4.4% (p = 0.14), Silicone oil residuals was 7.4 ± 3.2% versus 7.1 ± 2.8% (transpupillary vs. three-port, p = 0.71). Preoperative versus postoperative BCVA (logMAR) was 1.49 ± 0.61 versus 1.42 ± 0.61 in transpupillary approach (p = 0.28) and 1.53 ± 0.48 versus 1.45 ± 0.57 in three-port approach (p = 0.11). Transpupillary approach resulted in lower IOP at postoperative day 2 (12.2 ± 2.3 mmHg vs. 13.5 ± 2.2 mmHg, p < 0.05), while postoperative follow-up at 1 month revealed no significant difference (p = 0.21).ConclusionsTranspupillary silicone oil removal combined with micro-incision phacoemulsification cataract surgery is less invasive and can be an alternative in some circumstances.

Clinical analysis on rhegmatogenous retinal detachment accompanined with diabetic retinopathy

Objective To analyze the clinical characteristics and treatment methods of rhegmatogenous retinal detachment(RRD) accompanined with diabetic retinopathy(DR). Methods The data of 12 eyes of 12 cases with RRD accompanined with DR from Jun.2011 to May 2016 were collected and analyzed retrospectively. Results All cases were treated with pars plana vitrectomy(PPV), panretinal photocoagulation(PRP) and silicone oil tamponde. Topical antibiotics, glucocorticoid, mydriatic eye drops and Chinese medicine oral were applied after surgey. FFA examination was performed at 2 weeks- 2 months after opration for pointing out clearly diabetic retinopathy staging. The proliferative diabetic retinopathy and severe non-proliferative diabetic retinopathy were treated by PRP in 7 cases.All cases underwent silicone oil removal 3 months after surgery, then followed up for more than 3 months.The visual acuity was improved and the retinal was reattached. Conclusion Rhegmatogenous retinal detachment accompanined with diabetic retinopathy is treated with PPV firstly. PRP and FFA after opration are necessary. Key words: Retinal detachment, rhegmatogenous; Retinopathy, diabetic; Surgery; Fundus fluorescein angiography; Photocoagulation, panretinal, laser

Surgical outcomes of rhegmatogenous retinal detachment associated with ocular toxoplasmosis

To evaluate the anatomical and functional outcomes of surgical treatment of retinal detachment secondary to ocular toxoplasmosis. A retrospective analysis of data from patients who had undergone vitreoretinal surgery for retinal detachment secondary to ocular toxoplasmosis was conducted. The parameters that were analyzed include surgical procedures, anatomical outcomes, visual acuity, and postoperative complications. This study included 22 patients, of which 13 were female (59.1%). The mean age was 28.5 years (SD ± 14.5, range 12-78 years) and the follow-up period varied from 1 to 163 months (mean 64 months). The mean baseline best-corrected visual acuity (BCVA) was 2.0 logMAR (SD ± 1.0). A total of 31 surgeries were performed, and the retina was reattached in 15 patients (68.2%) immediately after the first surgery and in 20 patients (90.9%) at a later point. The mean postoperative BCVA improved to 1.3 logMAR (SD ± 0.9) (p<0.05). Nineteen patients (86.4%) underwent cataract surgery with intraocular lens implant, and 12 patients (60.0%) underwent silicone oil removal. Five patients (22.7%) exhibited elevated intraocular pressure, and 1 patient (4.5%) developed hypotonia. Surgical treatment of retinal detachment secondary to ocular toxoplasmosis resulted in considerable anatomical and functional improvement. Although PPV with silicone oil injection demonstrated the best outcomes, it is not reasonable to conclude that this is the best surgical approach given the small number of patients included in this study.

The comparison of immersion B-scan guided with respective sonic velocity and Lenstar LS900 onmeasurement of axial length in silicone oil-filled eyes

Objective To evaluate the accuracy of the biometry using immersion B scan and partial coherence interferometry (Lenstar LS900) for the axial length (AL) of silicone oil-filled eyes respectively. Methods Thirty-five silicone oil-filled eyes (38 patients) were included in the study. All of these eyes underwent silicone oil removal, cataract extraction and intraocular lenses implantation. The AL of all the silicone oil-filled eyes was measured with A/B-scan ultrasound and Lenstar LS900 before operation and with Lenstar LS900 after operation. The measured distance was compared respectively. The method of immersion B-scan guided with respective sonic velocity. AL was the sum of corneal thickness, anterior chamber depth, lens thickness, the apparent length of oil bubble (velocity values 996 m/s), the depth of the water layer beneath the oil bubble. Results Thirty-one eyes were measured with Lenstar LS900 before silicone oil removal, and the mean AL was (24.12±1.70) mm, 7 eyes failed to get the results before the operation; 36 eyes were measured with Lenstar LS900 after silicone oil removal, and the mean AL was (24.45±1.89) mm. All eyes were measured with B-scan before silicone oil removal, and the mean AL was (24.87±2.52) mm. The difference (31 eyes) of AL measurement before silicone oil removal by two methods was (−0.00±0.09) mm; the difference (31 eyes) between pre- and post-surgical AL measurement with Lenstar LS900 was (0.02±0.07) mm; the difference (36 eyes) between pre-surgical AL measured with B-scan and post-surgical AL measured with Lenstar LS900 was (−0.02±0.11) mm. All the differences were not statistically significant (t=−0.205, 1.752, −1.280; P>0.05). The consistency of the results measured by two methods was well in Bland-Ahamn analysis. Conclusions Measurement results of AL between immersion B-scan guided with respective sonic velocity and Lenstar LS900 are high repeatability on silicone oil-filled eyes. The AL of silicone oil-filled eyes can be measured reliably by immersion B-scan guided with respective sonic velocity. Key words: Axial length, eye; Silicone Oils; Ultrasonography/methods

Incidence and Risk Factors of Cystoid Macular Edema after Vitrectomy with Silicone Oil Tamponade for Retinal Detachment.

To investigate the incidence and risk factors of cystoid macular edema (CME) after silicone oil (SO) injection for retinal detachment. Fifty-eight patients with retinal detachment treated by vitrectomy with SO tamponade during 2011 to 2015 were retrospectively assigned to CME and non-CME groups. Patients underwent complete ophthalmological examination, including color fundus photography and preoperative and postoperative optical coherence tomography. Risk factors for CME during SO tamponade were determined by regression analyses. Of the 58 eyes, 21 (36.2%) exhibited CME. The presence of posterior staphyloma in the CME group was significantly more frequent than in the non-CME group (p = 0.026). There were no significant differences in other demographic or clinical characteristics between the CME and non-CME groups. Significant correlations were observed between CME after vitrectomy with SO tamponade and the presence of posterior staphyloma (odds ratio, 4.03; p = 0.031). Of the 21 eyes with CME, 13 underwent SO removal, among which 11 experienced resolution of CME with or without further intervention. The presence of posterior staphyloma is significantly associated with CME after vitrectomy with SO tamponade. Patients with retinal detachment exhibiting posterior staphyloma should be evaluated for potential CME during SO tamponade.