Underwent Coronary Artery Bypass Grafting Research Articles

Comparison of De Ritis Rate for Del Nido Versus Blood Cardioplegia in Patients Who Underwent Coronary Artery Bypass Graft Under Cardiopulmonary Bypass

Aim: Within the scope of this research, we aimed to compare the liver function tests, liver enzymes and De Ritis ratio (AST/ALT) of patients given Del Nido cardioplegia and blood cardioplegia in coronary heart surgery. Methods: This retrospective study included a total of 80 patients who underwent CPB-guided coronary heart surgery (CABG) with 40 Del Nido cardioplegia solutions and 40 blood cardioplegia solutions. CPB-guided coronary heart surgery patients given Del Nido cardioplegia solution were determined as the first group (Group 1), and patients given blood cardioplegia were determined as the second group (Group 2). Results: Preoperative and postoperative aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, direct bilirubin, and gamma-glutamyl transferase (GGT) levels of the groups were similar (p

989-P: The Effect of Continuous Glucose Monitoring on Postoperative Glucose Control in People with Type 2 Diabetes Mellitus Undergoing Coronary Artery Bypass Grafting—A Randomized Clinical Trial

989-P: The Effect of Continuous Glucose Monitoring on Postoperative Glucose Control in People with Type 2 Diabetes Mellitus Undergoing Coronary Artery Bypass Grafting—A Randomized Clinical Trial

Characteristics and In-Hospital Outcomes of Patients Who Underwent Coronary Artery Bypass Grafting during Hospitalization for ST-Segment Elevation or Non-ST-Segment Elevation Myocardial Infarction.

Little is known about the outcomes of patients with ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) who undergo coronary artery bypass grafting (CABG) in the current percutaneous coronary intervention (PCI) era. We analyzed 25120 acute myocardial infarction (AMI) patients hospitalized between January 2011 and December 2016. In-hospital outcomes were compared between patients who underwent CABG during hospitalization and those who did not undergo CABG in the STEMI group (n = 19428) and NSTEMI group (n = 5692). Overall, CABG was performed in 2.3% of patients, while 90.0% of registered patients underwent primary PCI. In both the STEMI and NSTEMI groups, patients who underwent CABG were more likely to have heart failure, cardiogenic shock, diabetes, left main trunk lesion, and multivessel disease than those who did not undergo CABG. In multivariable analysis, CABG was associated with lower all-cause mortality in both the STEMI group (adjusted odds ratio [OR] = 0.43, 95% confidence interval [CI] 0.26-0.72) and NSTEMI group (adjusted OR = 0.34, 95% CI 0.14-0.84). AMI patients undergoing CABG were more likely to have high-risk characteristics than those who did not undergo CABG. However, after adjusting for baseline differences, CABG was associated with lower in-hospital mortality in both the STEMI and NSTEMI groups.

Complete Coronary Revascularization and Outcomes in Patients Who Underwent Coronary Artery Bypass Grafting: Insights from The REGROUP Trial

There is growing evidence in support of coronary complete revascularization (CR). Nonetheless, there is no universally accepted definition of CR in patients who undergo coronary bypass grafting surgery (CABG). We sought to investigate the outcomes of CR, defined as surgical revascularization of any territory supplied by a suitable coronary artery with ≥50% stenosis. We performed a preplanned subanalysis in the Randomized Trial of Endoscopic or Open Saphenous Vein Graft Harvesting (REGROUP) clinical trial cohort. Of 1,147 patients who underwent CABG, 810 (70.6%) received CR. The primary outcome was a composite of major adverse cardiac events (MACEs), including death from any cause, nonfatal myocardial infarction, or repeat revascularization over a median 4.7 years of follow-up. MACE occurred in 175 patients (21.6%) in the CR group and 86 patients (25.5%) in the incomplete revascularization (IR) group (hazard ratio [HR] 0.87, 95% confidence interval [CI] 0.67 to 1.13, p = 0.29). A total of 97 patients (12.0%) in the CR group and 48 patients (14.2%) in the IR group died (HR 0.93, 95% CI 0.65 to 1.32, p = 0.67); nonfatal myocardial infarction occurred in 49 patients (6.0%) in the CR group and 30 patients (8.9%) in the IR group (HR 0.76, 95% CI 0.48 to 1.2, p = 0.24), and repeat revascularization occurred in 62 patients (7.7%) in the CR group and 39 patients (11.6%) in the IR group (HR 0.64; 95% CI 0.42 to 0.95, p = 0.027). In conclusion, in patients with a great burden of co-morbidities who underwent CABG in the REGROUP trial over a median follow-up period of a median 4.7 years, CR was associated with similar MACE rates but a reduced risk of repeat revascularization. Longer-term follow-up is warranted.

The Effect of Using Walking Aids on Pain and Mobility Levels of Patients Underwent Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial

The Effect of Using Walking Aids on Pain and Mobility Levels of Patients Underwent Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial

Abstract 16738: Impact of Remnant Cholesterol Level on Long-Term Outcomes in Patients With Multivessel Disease Undergoing Coronary Artery Bypass Grafting

Introduction: The remnant cholesterol (RC) is being increasingly documented as an important risk factors of coronary artery disease. Thus far, the impact of RC level on the long-term outcomes of patients with multivessel coronary artery disease (MVD) undergoing coronary artery bypass graft (CABG) has not been investigated. Hypothesis: Elevated RC level is associated with increased risk of MACCEs in patients with MVD undergoing CABG. Methods: All patients who were diagnosed with multivessel coronary artery disease and undergoing CABG between 2011 and 2020 were considered for enrollment. RC was calculated as total cholesterol minus HDL-C minus LDL-C. Patients were categorized by RC thresholds and the occurrence of major adverse cardiovascular and cerebrovascular events (MACCEs) was examined according to the RC level at one-year post-CABG. Results: A total of 2,072 patients (60.8 ± 8.3 years; 83.5% men) were included in this study. Patients was divided into four groups: RC < 0.5 mmol /L, RC of 0.5-0.99 mmol/L, RC of 1.0-1.49, mmol/L, and RC ≥ 1.5 mmol/L. During a median follow-up of 4.2 years after the 1-year assessment, 25.0% of the patients had occurrences of MACCEs. The multivariable adjusted hazard ratios (95% CI) for MACCEs, cardiac death, nonfatal myocardial infarction, re-revascularization, cardiac rehospitalization (admission because of angina or heart failure) and nonfatal stroke, were respectively 2.49 (1.99-3.12), 2.20 (1.18-3.86), 3.18 (2.16-5.84), 3.02 (2.12-4.34), 1.93 (1.42-2.87), and 1.37 (0.83-2.27) in patients with RC ≥ 1.50 mmol/L, compared with patients with 1-year RC < 0.5 mmol/L. The 1-year RC level was significantly associated with MACCEs, with the lowest risk of MACCEs reflected in the patients with RC < 0.5 mmol/L. Conclusions : In patients with MVD undergoing CABG, the RC level at one-year after CABG were independently associated with long-term outcomes.

Residential Greenness and Long-term Mortality Among Patients Who Underwent Coronary Artery Bypass Graft Surgery.

Studies have reported inverse associations between exposure to residential greenness and mortality. Greenness has also been associated with better surgical recovery. However, studies have had small sample sizes and have been restricted to clinical settings. We investigated the association between exposure to residential greenness and all-cause mortality among a cohort of cardiac patients who underwent coronary artery bypass graft (CABG) surgery. We studied this cohort of 3,128 CABG patients between 2004 and 2009 at seven cardiothoracic departments in Israel and followed patients until death or 1st May 2021. We collected covariate information at the time of surgery and calculated the patient-level average normalized difference vegetation index (NDVI) over the entire follow-up in a 300 m buffer from the home address. We used Cox proportional hazards regression models to estimate associations between greenness and death, adjusting for age, sex, origin, socioeconomic status, type of hospital admission, peripherality, air pollution, and distance from the sea. Mean age at surgery was 63.8 ± 10.6 for men and 69.5 ± 10.0 for women. During an average of 12.1 years of follow-up (37,912 person-years), 1,442 (46%) patients died. A fully adjusted Cox proportional hazards model estimated a 7% lower risk of mortality (HR: 0.93, 95% CI = [0.85, 1.00]) per 1 interquartile range width increase (0.04) in NDVI. Results were robust to the use of different buffer sizes (100 m-1,250 m from the home) and to the use of average NDVI exposure during the first versus the last 2 years of follow-up. Residential greenness was associated with lower risk of mortality in CABG patients.

Predictive Value of Nesfatin-1, Galectin-3, Ghrelin, and Leptin Expressions in Patients with Metabolic Syndrome Who Underwent Coronary Artery Bypass Graft (CABG) Surgery

Predictive Value of Nesfatin-1, Galectin-3, Ghrelin, and Leptin Expressions in Patients with Metabolic Syndrome Who Underwent Coronary Artery Bypass Graft (CABG) Surgery

Homelessness and Race are Mortality Predictors in US Veterans Undergoing CABG

Coronary artery disease requiring surgical revascularization is prevalent in United States Veterans. We aimed to investigate preoperative predictors of 30-day mortality following coronary artery bypass grafting (CABG) in the Veteran population. The Veterans Affairs Surgical Quality Improvement (VASQIP) national database was queried for isolated CABG cases between 2008 and 2018. The primary outcome was 30-day mortality. A multivariable logistic regression was performed to assess for independent predictors of the primary outcome. A P-value of <0.05 was considered statistically significant. A total of 32,711 patients were included. The 30-day mortality rate was 1.37%. Multivariable analysis identified the following predictors of 30-day mortality: African-American race (OR 1.46, 95% CI 1.09-1.96); homelessness (OR 6.49, 95% CI 3.39-12.45); female sex (OR 2.15, 95% CI 1.08-4.30); preoperative myocardial infarction within 7 days (OR 1.49, 95% CI 1.06-2.10) or more than 7 days before CABG (OR 1.34, 95% CI 1.04-1.72); partially/fully dependent functional status (OR 1.44, 95% CI 1.07-1.93); chronic obstructive pulmonary disease (OR 1.54, 95% CI 1.24-1.92); mild (OR 1.48, 95% CI 1.04-2.11) and severe aortic stenosis (OR 2.06, 95% CI 1.37-3.09); moderate (OR 1.88, 95% CI 1.31-2.72), or severe (OR 2.99, 95% CI 1.71-5.22) mitral regurgitation; cardiomegaly (OR 1.73, 95% CI 1.35-2.22); NYHA Class III/IV heart failure (OR 2.05, 95% CI 1.10-3.83); and urgent/emergent operation (OR 1.42, 95% CI 1.08-1.87). The 30-day mortality rate in US Veterans undergoing isolated CABG between 2008 and 2018 was 1.37%. In addition to established clinical factors, African-American race and homelessness were independent demographic predictors of 30-day mortality.

Management and predictors of clinical events in 75 686 patients with acute myocardial infarction

Although mortality in patients with acute myocardial infarction (MI) has decreased substantially over the last few decades in many countries, MI remains a major threat to public health. To assess the number and outcomes of patients hospitalized for acute MI in Poland in 2018 as well as proportions of patients participating in cardiac rehabilitation and undergoing invasive cardiac procedures following discharge. We used public databases. We included all patients hospitalized for acute MI in Poland in 2018 and assessed event-free survival along with uptake of invasive cardiac procedures, cardiac rehabilitation, and consultations with cardiologists. A total of 75868 patients (mean age, 68.8 years) were hospitalized for acute MI in Poland in 2018 (the admission rate, 197.0 per 100000 inhabitants). In-hospital mortality was 8.4%, while one-year mortality was 17.3% (one-year post-discharge mortality was 9.8%). Approximately 75% and 96% of discharged patients consulted a general practitioner, whereas 12% and 62% consulted a cardiologist, 5% and 19% underwent percutaneous coronary intervention, 0.6% and 2.9% un-derwent coronary artery bypass grafting, while 0.04% and 1.9% had an implantable cardioverter defibrillator implanted within 30 days and 365 days following discharge. The participation rate in cardiac rehabilitation within the first 14 days following discharge was 11%, within the first 30 days was 19%, and within 365 days was 35%. In-hospital and post-discharge mortality is still high in Poland. The access to cardiac consultations and cardiac rehabilitation following MI is insufficient. There is considerable potential for a further decrease in mortality in patients suffering from MI in Poland.

Journey From Experiences That Left Trace to Today in Patients Who Underwent Coronary Artery By-pass Graft Surgery

Objectives: This study aims to make the experiences of patients who underwent coronary artery bypass graft surgery visible and to understand them more deeply. Methods: This qualitative study was conducted through interviews with 10 coronary artery bypass graft patients. Heidegger’s phenomenological approach was used as a method. The data for the study was collected through Demographic Information Form and Semi-Structured Interview Form between November 2019-March 2020. Results: The ages of the participants varied between 53 and 79 and they underwent coronary artery bypass graft surgery a minimum of a year ago. The interviews yielded two categories: emotions and experiences about the bypass surgery as “Perioperative period experiences that left a trace” and today’s emotions and experiences as “Now/Nothing is as it was before”. Also, nine subthemes were identified. Conclusion: The Patients’ experiences that leave a trace involved reflections of the culture and faith, and it was obvious that they were inclined to find a new perspective for their changed lives and health. The results show the necessity of incorporating the sociocultural values and beliefs of patients in the care process.

Comprehensive Rehabilitation of Cardiac Surgery Patients with Acute Left Ventricular Failure who Underwent Coronary Artery Bypass Grafting with Cardiopulmonary Bypass

Aim: To develop and implement a comprehensive rehabilitation of cardiosurgical patients with acute left ventricular failure who underwent on-pump coronary artery bypass grafting. Materials and Methods: 500 patients underwent on-pump coronary artery bypass grafting. Sixty patients who required inotropic support in the postoperative period were selected. The patients were divided into two groups of 30 people each. In both groups, psychological and physical rehabilitation was carried out in accordance with the algorithm developed by us. The protocol EACTS, 2017 for the main group was supplemented with a metabolic support component, the introduction of a combination of levocarnitine and arginine. Results: Psychological and physical algorithm was developed and implemented. In the basic group, the recovery time of hemodynamics and the total dose of the inotropic drug were shorter/lower than in the control one. Conclusions: Stressful moments informing the patient in the perioperative period is a powerful tool for psychological rehabilitation. Aerobic training and respiratory physiotherapy are mandatory elements of physical rehabilitation. The introduction of a combination of levocarnitine and arginine has a positive effect on the terms of activation of patients, and reduces the stay in the intensive care unit.

Abstract 13072: Association Between Baseline Lipoprotein(a) and Five-Year Outcomes in Patients Underwent Coronary Artery Bypass Grafting: A Post-Hoc Analysis of DACAB Trial

Introduction: Serum lipoprotein(a) [Lp(a)] is genetically determined and has been proposed to be associated with coronary artery lesion severity and clinical outcomes in coronary artery disease (CAD). But some researches suggested heterogeneous effects and marked variations of Lp(a) level between ethnic groups. The aim of this study was to investigate the impact of baseline Lp(a) on five-year clinical outcomes in Chinese population who underwent coronary artery bypass grafting (CABG). Methods: We performed a post-hoc analysis of the DACAB trial (NCT02201771), in which patients aged 18 to 80 years, male or female, underwent primary, isolated and elective CABG, were randomly assigned to receive different antiplatelet treatments. Serum Lp(a) was obtained and analyzed in 270/272 patients of one single center. The primary outcome was major adverse cardiovascular events (MACE). MACE-5 included all-cause death, myocardial infarction, stroke, repeated revascularization and rehospitalization for unstable angina, and MACE-3 included cardiovascular death, myocardial infarction, and stroke. The mean follow-up reached 59.4±9.4 months. Results: The baseline characteristics were generally comparable. High Lp(a) level was identified in 71 (26.3%) (cut-off ≥30mg/dL) and 33 (12.2%) (cut-off ≥50mg/dL) patients, respectively. During 5-year follow-up, MACE-5 reported in high and low Lp(a) group were 34.2% vs 28.8% when the cut-off value was 30mg/dL (hazard ratio [HR], 1.11; 95% CI, 0.69-1.78, p=0.66). While the cut-off value was 50mg/dL, MACE-5 reported in high and low Lp(a) group were 39.4% vs 28.9% (HR, 1.32; 95% CI, 0.73-2.38, p=0.36). Similar results were observed in MACE-3 (Cut-off value 30mg/dL: 24.2% vs 21.9%, HR 1.08, p=0.78; Cut-off value 50mg/dL: 27.3% vs 21.8%, HR 1.24, p=0.56). No statistical significant difference was achieved between the two groups. Conclusions: In this single center post-hoc analysis, baseline Lp(a) level ≥30mg/dL or ≥50mg/dL had no statistical significant association with 5-year MACE in post-CABG Chinese population. But higher baseline Lp(a) levels seem to be associated with more MACE in longer follow-up. Larger sample size from multicenter are needed to confirm our findings.

Functional Capacity Change after Phase II Cardiac Rehabilitation as a Predictor of Major Adverse Cardiac Event in Left Ventricular Dysfunction Patients Underwent Coronary Artery Bypass Grafting

Background: Phase II cardiac rehabilitation is essential for management post coronary artery bypass graft (CABG), especially in patients with left ventricular systolic dysfunction. Change in functional capacity after phase II cardiac rehabilitation (∆METs) is an indicator of cardiopulmonary and hemodynamic improvement after CABG. This study assessed the correlation of ∆METs as a predictor of major adverse cardiac event (MACE) 3 months after CABG in patients with left ventricular systolic dysfunction. Methods: A cohort study was conducted on patients with left ventricular systolic dysfunction who underwent CABG between January 2019 to January 2021. Then patients were recruited to phase II cardiac rehabilitation, ∆METs was measured and tabulated by differences of functional capacity before and after the program. The abnormalities of ∆METs were discovered as a predictor of MACE determined by cut-off point, which is combination of death and rehospitalization. Patients were monitored for 3 months after CABG. Result: Among 91 patients, 24.2% had MACE (6.6% death and 17.6% rehospitalization). We found significant correlation between ∆METs and MACE with cut-off point 3.25 METs (p &lt;0.001). Multivariate analysis using logistic regression showed lower ∆METs group had significant correlation with MACE (OR 0.135; p 0.03). Kaplan Meier survival analysis showed lower ∆METs group was predictor of MACE on 3 months after CABG, risk of MACE occurrence 3.9 times than higher ∆METs group (p &lt;0.001). Conclusion: Change in functional capacity could predict MACE on 3 months follow-up of left ventricular systolic dysfunction patients who underwent CABG. Keywords: Change in functional capacity; left ventricular systolic dysfunction; MACE; CABG.

Symptoms and Care Satisfaction in Patients Who Underwent Coronary Artery Bypass Graft Surgery

Objective: This study was conducted to investigate of symptoms and care satisfaction in patients who had a coronary artery bypass graft (CABG) surgery. Method: The study population consisted of patients who had a coronary artery bypass graft surgery in a public and a foundation hospital in Istanbul between December 2018 and May 2019 and the study sample 176 patients who met the inclusion criteria and agreed to take part in the study. The study data were collected using the self-report method with the help of a Patient Description Form, the Heart Surgery Symptom Inventory (HSSI) and the Newcastle Satisfaction with Nursing Care Scale (NSNS). The data were analysed on the SPSS version 22.0 software. The data were analysed using numbers, percentages, minimum and maximum values, means and standard deviations, t-test, variance analysis and Pearson correlation analysis. Results: The patients were found after their CABG surgery to experience pain, shortness of breath, fatigue, lack of appetite, nausea and wound-related symptoms. The most common complaint of the patients after the surgery was sleep problems and the least common wound-related symptoms. The mean HSSI score of the participating patients was 71.22±31.39 and the mean NSNS score 52.87±22.54, which meant that the severity of their post-surgery symptoms and their satisfaction with care were at a moderate level. Post-surgery pain, lack of appetite, nausea and wound-related symptoms were found to have a statistically significant moderate negative correlation with care satisfaction (p

Retrospective Evaluation of the Pre- and Postoperative Neutrophil-Lymphocyte Ratio as a Predictor of Mortality in Patients Who Underwent Coronary Artery Bypass Grafting.

We aimed to investigate the neutrophil-lymphocyte ratio (NLR) as a predictor of mortality in patients, who had undergone on-pump and off-pump coronary artery bypass grafting (CABG). This retrospective study comprised of 457 patients, who underwent CABG (323 on-pump and 134 off-pump) between January 2014 and October 2019. Preoperative, postoperative (PO) 1st hour, PO 1st day, and PO 5th day neutrophil-lymphocyte ratios were calculated. The patients were compared, according to demographic, laboratory, and clinical data. A receiver operating characteristics curve was applied to estimate a cut-off value of NLR for mortality. The on-pump group was older (P = 0.001), had a lower Euroscore II (P = 0.036), had a higher graft number (P < 0.001), intensive care unit stay (P = 0.001), and all PO NLRs, except preoperative NLR. There were 14 (3.06%) patients with mortality. Overall (N = 457), PO 1st hour (P = 0.001), PO 1st day (P < 0.001), and PO 5th day (P = 0.016) NLRs were considerably higher in patients with mortality. While none of the NLRs revealed a significant difference in the off-pump group, PO 1st hour (P = 0.004) PO 1st day (P < 0.001), and PO 5th day (P = 0.007) NLRs were higher in patients with mortality in the on-pump group. The increase in odds ratio of PO NLR was higher in patients with mortality in the overall group of PO 1st day and in the on-pump group of PO 1st hour and PO 1st day. The best combination of sensitivity and specificity was reached at a cut-off value of 6.4 for PO 1st hour NLR and 31.8 for PO 1st day NLR. As in indicator of inflammatory state, NLR readily can be used as a predictor of mortality. Regardless of the CABG technique used, postoperative 1st hour and postoperative 1st day NLR >6.4 and 31.8, respectively, are highly related to mortality.

Potential of Circulating Proangiogenic MicroRNAs for Predicting Major Adverse Cardiac and Cerebrovascular Events in Unprotected Left Main Coronary Artery Disease Patients Who Underwent Coronary Artery Bypass Grafting

Objective: This study aimed to explore the association of 14 proangiogenic microRNAs (miRNAs) with major adverse cardiac and cerebrovascular events (MACCE) occurrence in unprotected left main coronary artery disease (ULMCAD) patients who underwent coronary artery bypass grafting (CABG). Methods: A total of 196 ULMCAD patients who underwent first ever CABG were recruited. The peripheral blood samples were collected prior to CABG, and then plasma samples were separated to detect expressions of 14 proangiogenic miRNAs by the reverse transcription quantitative PCR. Patients were regularly followed up to MACCE occurrence or 36 months after CABG. Results: MACCE occurrence at 1 year, 2 years, and 3 years was 7.1, 11.2, and 14.3%, respectively, and accumulating MACCE occurrence time was 32.7 (95% confidence interval: 31.5–33.9) months. Both Kaplan-Meier curves and univariate Cox’s regression analyses displayed that miR-let-7f, miR-19a, miR-126, miR-130a, and miR-378 high expressions were associated with lower accumulating MACCE occurrence. Furthermore, forward stepwise multivariate Cox’s regression disclosed that miR-let-7f high expression and miR-378 high expression independently predicted decreased accumulating MACCE occurrence, whereas BMI (>25.0 kg/m²), diabetes, previous stroke, and higher disease extent were independent predictive factors for elevated accumulating MACCE occurrence. Conclusion: Measurement of circulating proangiogenic miRNAs especially miR-let-7f, miR-19a, miR-126, miR-130a, and miR-378 helps predict MACCE risk in ULMCAD patients who underwent CABG.

Koroner Arter Baypas Greft Cerrahisi Uygulanan Hastalarda İnternal Karotis Arter Darlığı Olan ve Olmayanların Near İnfrared Spectroscopy ile rSO2 Değerlerinin Karşılaştırılması

Koroner Arter Baypas Greft Cerrahisi Uygulanan Hastalarda İnternal Karotis Arter Darlığı Olan ve Olmayanların Near İnfrared Spectroscopy ile rSO2 Değerlerinin Karşılaştırılması

Are Standard Follow-Up Parameters Sufficient to Protect Neurocognitive Functions in Patients with Diabetes Mellitus who Underwent Coronary Artery Bypass Grafting?

ObjectiveWe aimed to compare the effectiveness of cognitive function protection between the standard follow-up parameters and advanced neuromonitoring methods in diabetic patients who underwent coronary artery bypass grafting during cardiopulmonary bypass.MethodsStudy design was prospective and observational. Patients were separated into two groups, treated only with standard follow-up parameters (Group 1) and followed up with the change of regional cerebral tissue oxygenation (rSO2) by near-infrared spectroscopy (Group 2). Neurocognitive functions were evaluated preoperatively and postoperatively before discharge in all patients using the Montreal Cognitive Assessment (MoCA) test.ResultsCognitive functions of Group 2 patients in the postoperative period were significantly higher than Group 1 patients (P=0.001). The mean postoperative MoCA score of patients was significantly lower than the mean preoperative MoCA score in Group 1 (24.8±2.2 vs. 23.6±2.6, P=0.02). However, mild cognitive dysfunction was significantly lower in Group 2, compared to Group 1 (P=0.02).ConclusionIn patients followed up with standard parameters, a significant decrease in cognitive function was observed in the early period. However, the use of advanced neuromonitoring methods can significantly prevent this decrease in cognitive functions.

The Effect of Interval Training on Oxidative Stress Indices Among Women in Preterm Labor Underwent Coronary Artery Bypass Graft

Objectives: Oxidative stress indices are one of the factors that cause and exacerbate cardiovascular diseases in postpartum women, which can be changed with interval training. Therefore, the current study aimed at investigating the effect of interval training on oxidative stress indices among women in preterm labor undergoing the coronary artery bypass graft (CABG). Materials and Methods: This randomized clinical trial was conducted on 21 participants (the sample size was determined based on a similar study) from December 2018 to May 2019 at Shahid Madani hospital of Tabriz, Iran. After the random allocation of subjects to the training (n=11) and control (n=10) groups, demographic information was collected and their physical activity level was assessed using the Kaiser physical activity survey before and after the intervention. In addition, the levels of oxidative stress indices were measured 24 hours before and after the intervention using the blood sample. The participants completed an eight-week invention including 24 one-hour sessions according to the available protocol. Finally, data were analyzed by means of statistical tests such as the Shapiro-Wilk, Leven, and Student’s t-test at a significant level of &lt;0.05. Results: The effect of the aerobic exercise program on body weight loss, as well as body mass index (BMI) and body fat percentage changes was significant in the training group (P=0.011, P=0.004, and P=0.001, respectively). Based on the results, the serum and urine levels of 8-hydroxy-2-deoxyguanosine reduced significantly after the completion of the intervention (P=0.002 and P=0.001, respectively) in the training group. Conclusions: In general, aerobic exercise after CABG decreased the fat percentile, BMI, and oxidative stress indices in the subjects. Thus, these trainings could reduce oxidative stress indices by increasing tissue metabolism and oxygen consumption.