This study was accomplished to investigate the preference of clothing materials and the clothing demand performance for underwear and everyday dress of atopic patients. As this study was the research study by a use of a questionnaire, the finally total 987 copies of the collected questionnaires were used to analyze the data. SPSS was used for the statistical analysis of data. To analyze the data, frequency analysis, percentage, -test, reliability analysis, factor analysis, t-test, ANOVA and Duncan's multiple comparisons were used. The results obtained are as follows. In factor analysis for clothing materials and the demand performance which atopic patients favor, the preference factors for underwear materials were classified as pliability/a sense of weight, a sense of cold and warmth, tactility, and elasticity. Those for everyday wear were classified as pliability/surface roughness, a sense of cold and warmth, a sense of weight, and elasticity. And the demand performance factors for underwears were classified as thermophysiology, care convenience, and skin contact. Those for everyday wear were classified as comfortableness and care convenience. In the difference analysis for the preference and the demand performance, Both everyday wear and underwear showed a significant difference for the preference and the demand performance according to gender, age, income, education level, and occupation.