Uncemented Cup Research Articles

Modes of periacetabular load transfer to cortical and cancellous bone after cemented versus uncemented total hip arthroplasty: A prospective study using computed tomography‐assisted osteodensitometry

Stress-shielding and periprosthetic bone loss after total hip arthroplasty (THA) may be clinically relevant for high-demand patients. Analysis of cortical and cancellous bone density (BD) changes in vivo after THA is of interest to basic science researchers and joint reconstruction surgeons. An insufficient periprosthetic bone stock may predispose to migration, early mechanical failure, and major problems in revision surgery. We used computed tomography (CT)-assisted osteodensitometry in two prospectively analyzed cohorts after cemented (n = 21) versus noncemented (n = 23) cup fixation. Periacetabular BD (mgCaHa/mL) was determined in five CT scans cranial and five CT scans at the level of the cup 10 days and 26 months postoperatively. For press-fit cups BD decreased significantly in all CT cans except in four out of the five scans of cortical bone cranial to the cup. The decrease was highest for cancellous bone ventral to the cup (-45 to -53%). After cemented cup fixation, significant cortical BD decrease was seen ventral to the cup (-11 to -20%). Cancellous BD decrased only ventral (-21 to -31%) and in two scans cranial (-11 and -12%) to the cup. The modes of load transfer between cemented and uncemented cups differ fundamentally. Cemented cups especially prevent the loss of cancellous bone of the acetabulum while also cortical BD loss was significantly lower in most CT scans surrounding the cemented cup compared to the press-fit component. Long-term results are required to prove whether third-generation cementing technique protects periprosthetic BD and thereby improve implant survival.

Etiology, diagnosis and therapy of aseptic hip prosthesis loosening--a status assessment

Aseptic loosening of prostheses implants is the most common complication of hip replacement surgery and represents an increasing problem because of still rising numbers of primary arthroplasties. This study reviews the current scientific status of causes, diagnosis and therapeutical concepts on this theme in literature. We analyzed 6,386 cases on aseptic hip revision arthroplasties published in the international literature and separated the results for cup and femoral components. On this basis we deduced some recommendations for the operative procedure in aseptic hip revision surgery. The mean follow-up time of all studies was 6.8 years in the case of cemented and 4.0 years in the case of uncemented hip revision arthroplasty. As an average rate of rerevision, 15.1% was calculated for cemented cup revisions, 4.3% for uncemented cup revisions. Rates of aseptic loosening were 23.1% for cemented procedure, 8.8% for uncemented cup implants. Femoral revision implants showed an average aseptic loosening rate of 21.2% for cemented procedures and an average rate of rerevisions of 12.7%; uncemented procedures showed aseptic loosening in 4.4% of the cases and rerevision in 5.5%. For old, relatively immobile patients with reduced physical constitution, cemented reimplantation has still to be regarded as the method of choice. In young patients uncemented revision arthroplasty is to prefer both on the acetabular and the femoral side to achieve superior results with good long-term prognosis. Regarding the bony defects induced by loosening, bone grafting is recommended for cemented and uncemented reimplantation technique. In the case of aseptic hip revision arthroplasty, the therapeutical procedure has to be adapted especially to the age and general constitution of the patient as well as to the bony defects induced by prosthetic loosening. For the future, controlled studies should respect the initial condition of primary as well as revision arthroplasty in reporting the results.

Excellent long-term survival of an uncemented press-fit stem and screw cup in young patients: Follow-up of 75 hips for 15–18 years

Background The long-term results of uncemented total hip arthroplasties vary widely due to differences in design, metal alloy, coating, surface structure, and porosity.Patients and methods We retrospectively studied 75 cementless Zweymüller SL stems in combination with Endler titanium-backed threaded cups (Z-E) in 70 patients. 35 patients were women, and the mean age at surgery was 52 (24–68) years. 16 patients died and 1 emigrated, 7 patients (of which 1 later died) subsequently underwent revision, and the remaining 47 patients with 50 original arthroplasties were followed up after a median of 16 (15–18) years.Results Revision of 8 hips resulted in an 18-year Kaplan-Meier estimated overall survival rate of 88% (CI: 79–96). 6 of 7 cup revisions were due to liner wear and osteolysis, and 1 was due to aseptic loosening. 2 of 3 stem revisions were due to femoral loosening and 1 was due to fracture of the neck of the stem. The clinical results were good, with a mean Harris hip score of 89 (54–100). Half of 70 hips in 65 patients had ectopic bone formation. All unrevised implants were radiographically stable, with a mean liner wear of 0.07 mm/year.Interpretation These long-term results demonstrate that the combination of a Zweymüller SL stem and an Endler titanium-backed screw cup is a good hip arthroplasty in young and active patients. A prefixed polyethylene liner is a drawback, necessitating exchange of the whole cup in cases with polyethylene wear.

A new approach for assessment of wear in metal-backed acetabular cups using computed tomography: A phantom study with retrievals

Background and purpose Polyethylene wear is an important cause of aseptic loosening in hip arthroplasty. Detection of significant wear usually happens late on, since available diagnostic techniques are either not sensitive enough or too complicated and expensive for routine use. This study evaluates a new approach for measurement of linear wear of metal-backed acetabular cups using CT as the intended clinically feasible method.Material and methods 8 retrieved uncemented metal-backed acetabular cups were scanned twice ex vivo using CT. The linear penetration depth of the femoral head into the cup was measured in the CT volumes using dedicated software. Landmark points were placed on the CT images of cup and head, and also on a reference plane in order to calculate the wear vector magnitude and angle to one of the axes. A coordinate-measuring machine was used to test the accuracy of the proposed CT method. For this purpose, the head diameters were also measured by both methods.Results Accuracy of the CT method for linear wear measurements was 0.6 mm and wear vector angle was 27°. No systematic difference was found between CT scans.Interpretation This study on explanted acetabular cups shows that CT is capable of reliable measurement of linear wear in acetabular cups at a clinically relevant level of accuracy. It was also possible to use the method for assessment of direction of wear.

Porous tantalum uncemented acetabular shells in revision total hip replacement: Two to four year clinical and radiographic results

In cementless revision total hip arthroplasty (THA), achieving initial implant stability and maximising host bone contact is key to the success of reconstruction. Porous tantalum acetabular shells may represent an improvement from conventional porous coated uncemented cups in revision acetabular reconstruction associated with severe acetabular bone defects. We reviewed the results of 46 acetabular revisions with Paprosky 2 and 3 acetabular bone defects done with a hemispheric, tantalum acetabular shell and multiple supplementary screws. At a mean follow-up of 40 (24-51) months, one acetabular shell had been revised in a patient with a Paprosky 3B defect. Cementless acetabular revision with the tantalum acetabular shell demonstrated excellent early clinical and radiographic results and warrants further evaluation in revision acetabular reconstruction associated with severe acetabular bone defects.

Porous tantalum uncemented acetabular shells in revision total hip replacement: two to four year clinical and radiographic results

In cementless revision total hip arthroplasty (THA), achieving initial implant stability and maximising host bone contact is key to the success of reconstruction. Porous tantalum acetabular shells may represent an improvement from conventional porous coated uncemented cups in revision acetabular reconstruction associated with severe acetabular bone defects. We reviewed the results of 46 acetabular revisions with Paprosky 2 and 3 acetabular bone defects done with a hemispheric, tantalum acetabular shell and multiple supplementary screws. At a mean follow-up of 40 (24-51) months, one acetabular shell had been revised in a patient with a Paprosky 3B defect. Cementless acetabular revision with the tantalum acetabular shell demonstrated excellent early clinical and radiographic results and warrants further evaluation in revision acetabular reconstruction associated with severe acetabular bone defects.

Jumbo cups for revision of acetabular defects after total hip arthroplasty: a retrospective review of a case series

The treatment of acetabular bone defects presents a great challenge in revision total hip arthroplasty (THA). The purpose of this study was to evaluate the clinical and radiological outcome of revision THA using jumbo cups for acetabular reconstruction after applying the bone-grafting technique. We studied 17 patients with acetabular defects ranging from Type 2A to Type 3A according to Paprosky's classification. According to the AAOS-score twelve patients were classified as Type II and five patients as Type III. Uncemented press-fit cups with an outer diameter larger than 64 mm were used in all cases. Fifteen patients received morselized bone allografts. In eight patients an additional screw fixation was necessary. The mean follow-up period was 82 months (range 33-149). The mean Harris Hip Score was preoperatively 62 and at the time of the last follow-up examination 83 points (p = 0.007). Two acetabular components failed, one due to aseptic loosening and another one due to septic loosening. There was a trend of displacement of the femoral head centre towards the infero-lateral position after using jumbo cups that approached statistical significance (p = 0.065). Closure of acetabular defects of Types 2A to 3A according to Paprosky's classification and type II to III according to the AAOS-score respectively can be satisfactorily accomplished using jumbo cups after applying the bone-grafting technique.

Primary Total Hip Arthroplasty in Protrusio Acetabuli Using Impacted Morsellized Bone Grafting and Cementless Cups: A Medium-Term Radiographic Review

Thirty primary total hip arthroplasties were performed for protrusio acetabuli in 23 patients (mean age, 46 years) using impacted autologous bone grafting and a cementless porous-coated hemispheric cup without the use of metal cages or rings. At 2 to 10 years' follow-up (mean, 4.2 years), there was satisfactory radiographic evidence of consolidation of the graft in all cases. All acetabular components were considered to be stable with no instance of graft resorption. Clinical results were considered as excellent in 14 hips, good in 13 hips, fair in 2 hips, and poor in 1 hip. For younger patients with protrusio acetabuli, use of an uncemented porous-coated hemispheric cup with peripheral press-fit fixation and restoration of bone stock with impacted autologous bone grafting reflect a technically straightforward procedure that appears to give satisfactory medium-term results.

HYBRID TOTAL HIP REPLACEMENT: OUTCOME AFTER A MEAN FOLLOW UP OF 10 YEARS

Total hip replacement is one of the most successful surgical procedures of the modern surgical era. The method of fixation of implants continues to evolve, and as cemented acetabular fixation appears to be less durable than anticipated, the use of a cemented stem and an uncemented acetabulum - a so-called 'hybrid hip'- has become more popular. This paper reports the results of hybrid total hip replacement at an average of 10 years postoperatively. Primary hybrid total hip replacements carried out by a single surgeon in 1994 and 1995 were identified; patients were sent Oxford Hip Score and EuroQuol-5 Dimension quality-of-life questionnaires and, where necessary, a radiograph appointment. Questions about diabetes, cigarette smoking and hip dislocation were included. First postoperative and final radiographs were compared for stem subsidence, cup migration, stem position, osteolysis of the femur and pelvis, and evidence of loosening of both components. At 10-year follow up the revision rate for femoral component loosening was 2.9%. Fifteen per cent showed some abnormality at the femoral interface, not related to stem size and more common in titanium stems. Average hip score was 20.9, and quality-of-life measures indicated a high level of satisfaction. Hybrid total hip replacement gives excellent clinical outcomes with low revision rates for both components. The one-piece uncemented cup offers important advantages over modular devices, the use of which should be re-evaluated.

Structural femoral head allografts in revision surgery of loosened acetabular cups

Treatment of acetabular bone defects presents a great challenge in revision total hip arthroplasty (THA). Many methods of acetabular reconstruction have been described. The purpose of this study was to evaluate the midterm results of structural femoral head allografts for acetabular reconstruction. Thirty-six patients (33 females and 3 males) with acetabular defects ranging from type 2C to type 3B according to Paprosky's classification were included in the study. In all cases acetabular defects were closed using allografts from femoral heads. In 13 cases an uncemented press-fit cup, in 17 cases a cemented polyethylene socket, and in 6 cases a Burch-Schneider antiprotrusion cage was implanted. The mean follow-up period was 84.2 months (range: 5-147). Four acetabular components failed. All 36 grafts were osseointegrated radiographically and formed a mechanically stable construction. The mean Harris Hip Score at the most recent follow-up was 79.8 points. The distance from the obturator line to the prosthesis head center was 3.73 cm (1.17-5.80 cm) preoperatively and 2.79 cm (0.85-4.8 cm) postoperatively (p<0.05). The distance from the teardrop figure to the prosthesis head center was 3.02 cm (1.0-5.8 cm) preoperatively and 3.25 cm (1.6-4.8 cm) postoperatively (p<0.001). Closure of acetabular defects of types 2C to 3B according to Paprosky's classification can be satisfactorily accomplished using femoral head allografts. These allografts may facilitate future revision surgery. Femoral heads are readily available due to widespread primary total hip replacement surgery. However, the use of structural femoral head allografts for acetabular reconstruction is cost intensive. Individual patient-related aspects, such as the function of revision arthroplasty, have to be considered when planning revision arthroplasty using femoral head allografts.

Uncemented metal-on-metal acetabular component

Background Aseptic loosening is the major cause of implant failure. In cemented hip arthroplasty, failure of the acetabular side is mainly due to lysis caused by wear particles. By using an implant with low wear characteristics and by enhancing acetabular fixation using an uncemented implant, we aimed to reduce acetabular lysis and thereby loosening.Patients and methods This was a retrospective cohort study of 119 hips (101 patients) that had the Uncemented Fitmore cup (Sulzer Orthopedics). In 66 patients, the femoral component was CF-30 (Sulzer) used with cement. In the remaining 35 patients, thrust plate prosthesis (TPP) (Sulzer) was used. Of the 101 patients, 94 (112 hips) were available for study. Mean follow-up of the 94 patients was 7 (5–13) years.Results The mean preoperative Harris hip score was 38 and the mean postoperative Harris hip score was 89 at the last follow-up. Taking aseptic loosening as the endpoint, the survival rate of the Fitmore cup was 100% at 11 years.Interpretation The uncemented Fitmore acetabular cup with second generation metal-on-metal articulation showed good results with regard to aseptic loosening in the medium term.

Very low wear of non-remelted highly cross-linked polyethylene cups: An RSA study lasting up to 6 years

Background and purpose Highly cross-linked polyethylenes (PEs) all appear to reduce wear dramatically in laboratory studies, although there is substantial variation in this respect between manufacturers. Nonremelted cross-linked PE is almost as tough as unirradiated PE, but is not completely stable and can oxidize in vivo, as has been shown in recent retrievals studies.We had reported low wear and good clinical performance after 2 years for 10 non-remelted highly crosslinked PE cups compared to 16 conventional PE cups sterilized by gamma-in-air.Method Because of possible degradation by free radicals, we followed up both cohorts for 5 years (conventional PE) and 6 years (highly cross-linked PE).Result Mean (CI) proximal head penetration over the observation time was linear and measured 0.08 (0.02–0.13) mm for cross-linked PE and 0.42 (0.23–0.62) mm for conventional PE, and total penetration was 0.23 (0.1–0.35) mm and 0.75 (0.05–1.4) mm respectively. After subtracting creep, the annual wear for non-remelted highly cross-linked PE was below 6 µm. The cups had equally low migration and few radiolucencies.Interpretation The theoretical possibility of oxidation in non-remelted highly cross-linked PE may not show clinically. However, it may be that cemented cups with their thicker PE are more forgiving than metal-backed cups with thin PE moving in the locking mechanism. So far, we can conclude that the Crossfire highly crosslinked polyethylene cups performed very well clinically, with extremely low wear even after almost 6 years. This is reassuring, but care should be taken in extrapolating these results to other cross-linked PEs or uncemented cups where toughness of PE is more of an issue.

Separation of the apex hole eliminator screw in four failed hybrid total hip arthroplasties

Advancement or separation of the apex hole eliminator screw in uncemented Duraloc 100 cups (DePuy, Warsaw, Indiana, USA) has been recently reported as a radiographic finding without clinical effects. We report 4 patients with a separation of the apex hole eliminator screw in Duraloc 300 uncemented cups and aseptic failures of a hybrid total hip arthroplasty (acetabular osteolysis and femoral stem loosening). Revision surgery was performed when disabling pain and radiographic signs of loose components were present. Although difficult to determine, a relationship between the screw migration and the failure could have existed in these cases. Migration of the screw might not only be interpreted as a radiographic, clinically irrelevant finding. Its presence should alert the orthopaedic surgeon that the prosthesis is exposed to high intraarticular fluid pressures.

Separation of the Apex Hole Eliminator Screw in Four Failed Hybrid Total hip Arthroplasties

Advancement or separation of the apex hole eliminator screw in uncemented Duraloc 100 cups (DePuy, Warsaw, Indiana, USA) has been recently reported as a radiographic finding without clinical effects. We report 4 patients with a separation of the apex hole eliminator screw in Duraloc 300 uncemented cups and aseptic failures of a hybrid total hip arthroplasty (acetabular osteolysis and femoral stem loosening). Revision surgery was performed when disabling pain and radiographic signs of loose components were present. Although difficult to determine, a relationship between the screw migration and the failure could have existed in these cases. Migration of the screw might not only be interpreted as a radiographic, clinically irrelevant finding. Its presence should alert the orthopaedic surgeon that the prosthesis is exposed to high intraarticular fluid pressures.

Thirty-two Millimetre Heads and Accelerated Polyethylene Wear in Total Hip Arthroplasty

In total hip arthroplasty 32 mm heads are often used as the greater diameter is thought to contribute to improved stability. However, greater head diameter can also lead to greater volumetric wear. We compared polyethylene wear between patients with 32 mm heads and those with smaller heads. All patients who had Harris Galante1 metal-backed, uncemented cups inserted between 1986 and 1996 at our institute were annually reviewed clinically and radiographically. Accelerated polyethylene wear was noted between the fifth and seventh postoperative year in 17 out of 165 total hip replacements with 32 mm heads, but only in 21 out of 961 total hip arthroplasties with smaller femoral heads. In all 17 THRs, accelerated wear was also associated with thin polyethylene (<6 mm). This paper highlights a potentially serious problem. When 32 mm metal heads are used with uncemented cups and polyethylene liners, there is a risk of accelerated acetabular wear in patients with thin polyethylene.

No Increased Migration in Cups with Ceramic-on-Ceramic Bearing

Ceramic-on-ceramic hip replacements might stress the bone interface more than a metal-polyethylene because of material stiffness, microseparation, and sensitivity to impingement. To ascertain whether this potentially increased stress caused an increased cup migration we compared a ceramic-on-ceramic with a metal-on-polyethylene implant for cup migration. Sixty one patients (61 hips) undergoing THA for osteoarthritis were randomized to ceramic on ceramic (Ce/Ce) or cobalt-chromium on cross-linked polyethylene bearings (PE) in the same uncemented cup shell. Migration was followed with RSA. At 2 years we observed similar mean cup translations in the 3 directions (0.07-0.40 mm vs. 0.05-0.31 mm, Ce/Ce vs. PE), as well as similar rotations around the 3 axes (0.31-0.92 degrees vs. 0.57-1.40 degrees). WOMAC and SF-36 scores were also similar and no radiolucent lines or osteolysis found. The large migration seen in some cups in both implant groups will require close monitoring to ascertain the reasons. Mean proximal wear of the polyethylene liners measured 0.016 mm between 2 and 24 months. Our data suggest there is no increased cup migration in the ceramic-on-ceramic implant compared with the metal-on-polyethylene, and they seem an equally safe choice. However, the low wear measured with the more versatile and less expensive cross-linked polyethylene makes it a strong contender. Therapeutic Level I. See the Guidelines for Authors for a complete description of levels of evidence.

Long-term results of uncemented acetabular cups with an ACS polyethylene liner. A 14–16-year follow-up study

We assessed the clinical and radiographic results of 40 porous-coated acetabular cups with an Acetabular Cup System polyethylene liner over a minimum 14-year follow-up. Femoral head penetration was estimated using a software package. Fifteen cups were revised, 11 due to polyethylene liner rupture. All cups but two were radiographically stable, and 11 hips showed acetabular osteolysis. The overall femoral head penetration rate in hips without liner fracture with reference to the early penetration point was 0.1188+/-0.070 mm per year. Polyethylene liner fractures were associated with higher early femoral head penetration (P<0.0001) and a vertical cup position (P=0.0016). The 14-year survival without cup revision for any reason was 63.9%, 71.8% with no ACS polyethylene liner fracture and 65.3% with no acetabular osteolysis. Most cups showed a good clinical outcome in general, but major Acetabular Cup System liner failure and osteolysis were frequent. Patients with the ACS cups still in place should be monitored closely.

Radiographic Signs of Osseointegration in Porous-coated Acetabular Components

There currently is no direct method to radiographically determine osseointegration of an uncemented, porous-coated acetabular component. We defined five radiographic signs for detecting acetabular osseointegration: (1) absence of radiolucent lines; (2) presence of a superolateral buttress; (3) medial stress-shielding; (4) radial trabeculae; and (5) an inferomedial buttress. We assessed their ability to predict acetabular osseointegration by reviewing the postprimary and prerevision radiographs from a series of 119 total hip arthroplasties that had revision surgery. Each sign had a high positive predictive value for the presence of bone ingrowth (range, 92.2-96.3%). The absence of radiolucent lines, presence of superolateral buttresses, and presence of medial stress-shielding were the most sensitive signs for indicating bone ingrowth. Ninety-seven percent of the cups with three to five signs were bone ingrown, whereas 83% of the cups with one or no signs were unstable. When three or more signs were present, the positive predictive value of the radio-graphic test was 96.9%, the sensitivity was 89.6%, and the specificity was 76.9%. The five signs of acetabular osseointegration reliably predicted osseointegration, especially when used in combination. They can be used as a tool for radio-graphically assessing the status of patients with porous-coated uncemented cups. Diagnostic study, Level III (Study of nonconsecutive patients; without consistently applied reference "gold" standard). See the Guidelines for Authors for a complete description of levels of evidence.

Different loss of BMD using uncemented press-fit and whole polyethylene cups fixed with cement: Repeated DXA studies in 96 hips randomized to 3 types of fixation

Background In cemented THA, aseptic loosening of the cup is more common than loosening of the stem, while periprosthetic osteolysis of the socket resulting in difficult reconstruction problems has emerged as the most significant problem with cementless cup fixation.Patients and methods 90 patients (96 hips) scheduled for THA were stratified in three groups according to the method of fixation of the acetabular component: acrylic bone cement with fluoride (Cemex-F), porous-coated press-fit cup with ceramic coating (Trilogy, uncemented) and acrylic cement with gentamicin (Palacos). All patients received the Spectron EF stem. Acetabular bone mineral density was measured with dual-energy X-ray absorptiometry (DXA) 1 week postoperatively, and after 12 and 24 months. The periprosthetic BMD was evaluated in 5 ROIs positioned around the acetabular component.Results In the uncemented sockets, the BMD had decreased proximally and medially to the cup after 2 years. The difference was significant in the proximal region as compared to the control group (Palacos). No difference was noted between the 2 groups with cemented components after 2 years. Stepwise linear regression analysis showed that loss of periprosthetic BMD in the proximal high-pressure region after 2 years increased with higher postoperative BMD and when the uncemented design had been used.Interpretation Contrary to previous studies of cemented stems, the use of fluoride cement did not influence the periprosthetic BMD 2 years after the examination. Increased loss of BMD with use of uncemented press-fit cups in the region in which osteolytic lesions are commonly found suggests that stress shielding may initiate the development of this complication. Longer follow-up will, however, be necessary to substantiate this hypothesis.

Uncemented total hip arthroplasty for primary osteoarthritis in young patients: A mid-to long-term follow-up study from the Finnish Arthroplasty Register

Introduction The survival of total hip arthroplasties (THAs) has been considered to be poor in young patients. We evaluated the population-based survival of uncemented THA for primary osteoarthritis (OA) in patients under 55 years of age and the factors affecting survival.Methods The Finnish Arthroplasty Register was established in 1980. Between that year and 2003, 92,083 primary THAs were entered in the register, 5,607 of which were performed for primary OA in patients under 55 years of age. Using records from these 5,607 THAs, we selected uncemented femoral and acetabular components that had been used in more than 100 operations during the study period. Survival of both components (cup/stem) and their combinations were analyzed separately with the Kaplan-Meier analysis and the Cox regression model.Results All uncemented stems studied showed a survival rate of over 90% at 10 years. The Biomet Bi-Metric stem had a 95% (95% CI 93– 97) survival rate even at 15 years. Overall survival of the extendedly porous-coated Lord Madréporique stem (p = 0.003) and the proximally porous-coated Anatomic Mesh stem (p = 0.0008) were poorer than that of the Biomet Bi-Metric stem. When endpoint was defined as stem revision for any reason, results were generally similar; there was no difference, however, between the survival rates of the Lord Madréporique stem and the Bi-Metric stem.Of the acetabular components, the Biomet Universal, the ABG Il and the Harris-Galante II cups showed < 90% survival rates at 10 years with aseptic loosening as endpoint; at 13 years the corresponding survival rates were 94% (95% CI 91–97) for the Biomet Universal and 95% (95% CI 91–98) for the Harris-Galante II cups with aseptic loosening as endpoint. The PCA Pegged porous-coated uncemented cup showed a poor 13-year survival rate of 68% (95% CI 59–78) with aseptic loosening as endpoint. However, when endpoint was defined as any revision (including exchange of liner), the 10-year survival rates of all brands of cup except Harris-Galante II declined to under 80%.Interpretation Modern second-generation uncemented stems, with proximal circumferential porous- or HA-coating, seem to be a good choice for young patients with primary OA. Similarly, modern press-fit porous- and HA-coated cups appear to have good endurance against aseptic loosening in these young patients. However, liner revisions were common; thus, survival rates of uncemented cups were unsatisfactorily low. Polyethylene wear and unfavorable locking mechanisms between the metal shell and the polyethylene liner and their sequelae remain matters of concern in this young and active group of patients. ▪