Unbalanced Transmission Research Articles

The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice

Cholinergic striatal interneurons (ChIs) express the vesicular glutamate transporter 3 (VGLUT3) which allows them to regulate the striatal network with glutamate and acetylcholine (ACh). In addition, VGLUT3-dependent glutamate increases ACh vesicular stores through vesicular synergy. A missense polymorphism, VGLUT3-p.T8I, was identified in patients with substance use disorders (SUDs) and eating disorders (EDs). A mouse line was generated to understand the neurochemical and behavioral impact of the p.T8I variant. In VGLUT3T8I/T8I male mice, glutamate signaling was unchanged but vesicular synergy and ACh release were blunted. Mutant male mice exhibited a reduced DA release in the dorsomedial striatum but not in the dorsolateral striatum, facilitating habit formation and exacerbating maladaptive use of drug or food. Increasing ACh tone with donepezil reversed the self-starvation phenotype observed in VGLUT3T8I/T8I male mice. Our study suggests that unbalanced dopaminergic transmission in the dorsal striatum could be a common mechanism between SUDs and EDs.

Generation of Artificial ULF/ELF Electromagnetic Emission in the Ionosphere by Horizontal Ground‐Based Current System

AbstractThe feasibility of the detection of electromagnetic response in the upper ionosphere to ground large‐scale ultra‐low‐frequency (ULF) and extremely‐low‐frequency (ELF) transmitters by low‐Earth‐orbit (LEO) satellites is considered. As an example of such transmitters, we consider the ZEVS 82 Hz transmitter, FENICS installation driven by 0.5–150 Hz generator, and industrial 50 Hz unbalanced power transmission lines. We numerically model the ULF/ELF wave energy leakage into the upper ionosphere from an oscillating grounded linear power line of a finite length suspended above a ground with a finite resistivity. The numerical scheme is based on the theoretical formalism developed to describe the excitation of an electromagnetic field by a horizontal grounded dipole. A realistic altitudinal profile of the plasma parameters has been reconstructed with the use of the IRI ionospheric model. For the ZEVS transmitter powered by 200 A current the modeled amplitudes of electromagnetic response can reach in the upper nightside ionosphere up to 60 µV/m and 6 pT. The assumption of an infinite source scale overestimates the ionospheric response by a factor of ∼7 as compared with realistic scale 60 km of the ZEVS transmitter. Unbalanced 50 Hz current of 10 A in large‐scale (>100 km) power transmission lines can produce the electric response in the upper ionosphere that is sufficient to be detected by electric sensors at LEO satellite. The stimulation of artificial Pc1 pulsations (0.5 Hz) with amplitudes ∼1 pT and ∼10 µV/m by large‐scale (>100 km) power lines is possible with driving current >100 A. The use of decommissioned power lines can be a cheap and efficient tool to stimulate Pc1 pulsations in the ionosphere.

Grid-Forming Control of Three-Phase and Single-Phase Converters Across Unbalanced Transmission and Distribution Systems

In this work, we investigate grid-forming control for power systems containing three-phase and single-phase converters connected to unbalanced distribution and transmission networks, investigate self-balancing between single-phase converters, and propose a novel balancing feedback for grid-forming control that explicitly allows to trade-off unbalances in voltage and power. We develop a quasi-steady-state power network model that allows to analyze the interactions between three-phase and single-phase power converters across transmission, distribution, and standard transformer interconnections. We first investigate conditions under which this general network admits a well-posed kron-reduced quasi-steady-state network model. Our main contribution leverages this reduced-order model to develop analytical conditions for stability of the overall network with grid-forming three-phase and single-phase converters connected through standard transformer interconnections. Specifically, we provide conditions on the network topology under which (i) single-phase converters autonomously self-synchronize to a phase-balanced operating point and (ii) single-phase converters phase-balance through synchronization with three-phase converters. Moreover, we establish that the conditions can be relaxed if a phase-balancing feedback control is used. Finally, case studies combining detailed models of transmission systems (i.e., IEEE 9-bus) and distribution systems (i.e., IEEE 13-bus) are used to illustrate the results for (i) a power system containing a mix of transmission and distribution connected converters and, (ii) a power system solely using distribution-connected converters at the grid edge.

Analysis of the similarity design and vibration transmission characteristics of typical support structures of an aero-engine

In the vibration test of an entire aero-engine, the magnitude and phase of the unbalanced vector of the internal rotor must be identified based on the vibration signal of the measuring point on the casing. Therefore, in addition to understanding the vibration transmission law between the high- and low-pressure rotors under unbalanced excitation, the vibration transmission law of the support structure must be studied urgently. However, few studies have investigated the vibration transfer characteristics of typical support structures. In this study, the similarity design of typical support structures was first performed, and the structural parameters of the core member squirrel cage were determined using theoretical calculations. Subsequently, the bush and spring elements were used to establish the connection between the inner and outer rings of the bearing to realise the equivalent simulation of the bearing stiffness. Using this method, refined finite element models of elastic and rigid support structures were established, and the accuracy of the model was verified based on low-speed rotating vibration and hammering tests. Furthermore, the unbalanced vibration transmission law of typical support structures was studied, and the vertical vibration transmission law from an aero-engine bearing pedestal to the panel was established with the vibration transmission rate as the quantitative index. Finally, considering the vital role of the squirrel cage, the influence of the local stiffness degradation of the squirrel cage on the unbalanced vibration transmission of the elastic support structure was studied. The research methods and results of this study can provide a basis for aero-engine assembly as well as manufacturing and structural performance evaluation.

A Hybrid Opportunistic IoT Secure Routing Strategy Based on Node Intimacy and Trust Value

Routing strategy is one of the most important researches in Opportunistic Internet of Things (IoT), and it highly influences the efficiency of data transmission. In this paper, a hybrid Opportunistic IoT secure routing strategy based on node intimacy and trust value (HIRouter) is proposed to resolve the problem of unbalanced transmission efficiency and security in the message delivery process. According to the records of node encounter and message forwarding, the strategy proposed in this paper can calculate nodes’ intimacy and trust value. The messages are then forwarded based on the intimacy and trust value between nodes. Experimental results verify that HIRouter algorithm we proposed can improve the message delivery rates and reduce the overhead rate in the Opportunistic IoT with dense nodes and frequent interactions between nodes.

Time-Domain Wavefield Reconstruction Inversion Based on Unbalanced Optimal Transport

Wavefield Reconstruction Inversion (WRI) is a novel seismic inversion method with a more expansive search space and reduced non-linearity and is more robust than other conventional techniques (e.g., full waveform inversion, FWI) in terms of local minima. Most of the modifications and applications of WRI are generally employed in the frequency domain, while the current time-domain solutions for WRI are either based on rough approximations, which lead to inaccurate inversion results, or are computationally expensive due to the data-domain Hessian. Here, we will provide another perspective to address time-domain WRI and maintain its effectiveness, namely reducing non-linearity and the effects of “cycle-skipping” while ignoring the data-domain Hessian. On the basis of iteratively solving the inversion problem, the time-domain augmented wave equation is solved by approximating the reconstructed wavefield on the right as the current wavefield. Due to this approximation and the traditional <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">L</i> <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> measurement, the reconstructed wavefield based on the poor model will be inaccurate away from the receivers, which will affect the subsequent model inversion. To alleviate this problem, we incorporate the unbalanced optimal transmission (UOT) distance measurement into the inversion. This distance measurement method can accurately obtain the best misfit between two unbalanced signals. Moreover, the accurately measured misfit with low-frequency and long-wavelength acts as an extended source of the subsequent wavefield reconstruction, ensuring the reconstructed wavefield’s accuracy based on the defective initial model without excessive additional computation. The numerical results demonstrate the accuracy and applicability of the proposed method.

Accurate Formulation of the Skin and Proximity Effects in High-Speed Cable System

An efficient transmission line model of high-speed cables is established, to predict its response at a high-frequency region (up to 20 GHz). Especially, an appropriate conformal mapping technique is applied to formulate the per-unit-length parameters of high-speed cables. Moreover, the skin and proximity effects of the conducting wires and the outer shield are derived in the closed form. As a result, the AC resistance/ inductance of all the conducting materials due to the skin and proximity effects are accurately incorporated for both layered and unlayered conductors. Furthermore, the mixed-mode S-parameters are precisely predicted for both balanced and unbalanced transmission line cables in the high-frequency region. In addition, the effects of the nonuniformities and cable geometry deformation on the mode conversions are also investigated. The proposed model is firstly validated with commercial software tools, COMSOL, FEKO, and HFSS; then, we further performed physical measurements to verify our new algorithm.

An Unbalanced Synaptic Transmission: Cause or Consequence of the Amyloid Oligomers Neurotoxicity?

Amyloid-β (Aβ) 1-40 and 1-42 peptides are key mediators of synaptic and cognitive dysfunction in Alzheimer’s disease (AD). Whereas in AD, Aβ is found to act as a pro-epileptogenic factor even before plaque formation, amyloid pathology has been detected among patients with epilepsy with increased risk of developing AD. Among Aβ aggregated species, soluble oligomers are suggested to be responsible for most of Aβ’s toxic effects. Aβ oligomers exert extracellular and intracellular toxicity through different mechanisms, including interaction with membrane receptors and the formation of ion-permeable channels in cellular membranes. These damages, linked to an unbalance between excitatory and inhibitory neurotransmission, often result in neuronal hyperexcitability and neural circuit dysfunction, which in turn increase Aβ deposition and facilitate neurodegeneration, resulting in an Aβ-driven vicious loop. In this review, we summarize the most representative literature on the effects that oligomeric Aβ induces on synaptic dysfunction and network disorganization.

Collision-free and low delay MAC protocol based on multi-level quorum system in underwater wireless sensor networks

Underwater wireless sensor network (UWSN) is a typical application of wireless network in underwater environment, which mainly uses acoustic communication at present. However, due to the characteristics of high bit error rate, very limited bandwidth and high transmission delay, the data transmission collision of underwater communication is very serious. In order to reduce transmission collision and improve network performance, we propose a collision-free time slot scheduling MAC protocol based on multi-level quorum system for high loaded UWSNs. The proposed protocol can allocate different time slots for nodes in the same collision area, while realize space reuse for nodes in different collision areas. Considering the unbalanced data transmission of each node, a multi-level quorum system algorithm is constructed for fairness, which can allocate time slots on demand according to the data transmission amount of each node. In order to ensure reliable transmission of data, a light weight retransmission mechanism is designed to reduce the impact of long delay on channel duty cycle. Simulation results prove that the proposed MAC protocol can effectively avoid transmission collision, reduce transmission delay, improve system energy efficiency, and have good adaptability for different network topologies.

Analysis of balanced and unbalanced signal transmission lines and noise reduction technique for beam-current monitor in linear accelerators.

A signal transmission line and its characteristics were analyzed in detail for a beam-current monitor (CM) for long-pulsed electron beams. The monitor was based on a conventional current transformer, which comprised an induction coil wound around a ferrite core. The signal transmission and noise generation mechanism were analyzed by theoretical models based on balanced and unbalanced coaxial transmission circuits to effectively reduce noises superimposed on the beam-current signal waveform. The results of numerical analyses based on the theoretical models were in good agreement with those of an experiment for verification. It was found that the noise signals were generated by a high-power klystron operation and they were mode-transformed on the way to the transmission line. These results show that the locations of the grounded points in the transmission line were important. Based on a symmetrically configured three-line circuit theory, a new highly symmetrically configured coaxial transmission line is proposed to effectively suppress noises generated in CM. This report describes in detail the numerical and experimental analysis of a signal transmission line with coaxial cables for CM where the noise generation mechanism and its reduction technique are deeply involved.

Optimised TSO–DSO interaction in unbalanced networks through frequency‐responsive EV clusters in virtual power plants

The increased penetration of distributed energy resources (DERs) installed in distribution networks via power electronic converters reduces the overall rotating inertia of the power system, causing faster frequency dynamics after a large disturbance. However, these DERs coupled with energy storage systems (ESSs) can be managed to provide valuable grid support functions such as fast frequency response (FFR) and assist the transmission system operator (TSO) in frequency control. In this study, single- and three-phase clusters of electric vehicles (EVs), acting as mobile-ESSs, are grouped together as virtual power plants (VPPs) to centralise the provision of FFR for the distribution system operator (DSO) whilst considering network unbalance. Furthermore, the parameters of the EV clusters within each VPP are optimised to minimise the inertia-weighed maximum frequency deviation following a disturbance whilst adhering to network security and power quality constraints. To this aim, a variant of the metaheuristic optimisation algorithm called improved harmony search is used for the optimisation process. Finally, the merits of the proposed methodology are shown with an illustrative example of an unbalanced three-phase transmission and distribution network modelled in DIgSILENT PowerFactory. The results show that clusters of EVs grouped as VPPs effectively improve frequency support via the TSO–DSO interaction.

Signal Balancing in Unbalanced Transmission Lines

Balanced lines operating as transmission line interconnects are subjected to differential-mode to common-mode conversion (and vice versa) in situations where symmetry imbalances (e.g., caused by line bends) are unavoidable. In this paper, a technique to compensate for such symmetry imbalances, providing pure differential-mode signals at the differential output port of the line, is presented. Such technique uses a rat-race balun (to generate the differential-mode signal) with the isolated port conveniently loaded, and it is based on the modification of the characteristic impedance of one of the unbalanced lines. A detailed analysis that justifies this compensation technique (valid for any arbitrary four-port network) and provides the design equations is presented. The approach is validated through simulation and experiment, by demonstrating that common-mode signals are not transmitted to the differential output port of a bended (i.e., unbalanced) line pair.

Performance improvement in long overhead lines associated to single-phase faults due to atmospheric discharges

In this research, a new analysis is proposed to detect the correct extinction of secondary arc in the re-closure protection, for long overhead lines in 220 kV. A new methodology for increasing the success rate of single-phase reclosing is proposed, with transient analysis (EMPT-ATP) have been done for over voltage detection in long overhead transmission lines, re-closure effect and probability, maneuver of line reactors, transient recovery voltages (TRV) caused by secondary arc phenomenon, unbalanced transmission lines and resonance. Finally, a case study is implemented with real fault conditions. Later, in the discussion section, the relation to the strength of the grounding system is analyzed and over voltage effects in the power system with the verification of the secondary arc extinction and the correct procedure of analysis.

Analysis of Unbalanced and Inadequate Development of Power Grids

The principal contradiction facing Chinese society has evolved. What we now face is the contradiction between unbalanced and inadequate development and the people’s ever-growing needs for a better life. As power grids play a significant role in energy resource distribution and utilization, the quality of power grid development is the foundation of healthy social and economic development of China. This paper analyses the unbalanced and inadequate development of power grids. Firstly, current situation and problems of power grid development are analysed. Secondly, an evaluation system of unbalanced and inadequate development of power grids is built to quantitatively assess the development of power grids. The unbalanced development index system is composed of secondary indicators of unbalanced urban and rural grid development, unbalanced regional grid development and unbalanced load development. The inadequate development index system is divided into scale indicators, quality indicators, automation indicators and management indicators. Each secondary indicator is then further detailed into tertiary indicators. Then, a case study of provincial power grid is applied to prove the effectiveness of the proposed index system. Study results highlight some problems, for example, unbalanced transmission and distribution grid development, unbalanced urban and rural grid development, unbalanced regional grid development, inadequate distribution grid development, inadequate automatization etc. Lastly, future improvements and measures are pointed out.

A Multi-Layer Cluster Based Energy Efficient Routing Scheme for UWSNs

Underwater Wireless Sensor Networks (UWSNs) have emerged as a remarkable interest for scholars worldwide in terms of various applications such as monitoring offshore oil and gas reservoirs, pollution, oceans for defense, and other applications such as tsunami. Terrestrial Wireless Sensor Networks (TWSN) and UWSNs share many characteristics apart from having different communication medium and working environment as UWSNs face the challenges of low-bandwidth, long latency, and high bit error rate. These have caused for UWSNs many problems such as low reliability, packet retransmission, and high consumption of energy. To alleviate the aforementioned issues, many techniques have been proposed. However, most of them merely consider the issue of hotspot which occurs due to the unbalanced transmission of load on sensor nodes near the surface sink. In this article, we propose a multi-layer cluster-based Energy Efficient (MLCEE) protocol for UWSNs to address the issue of hotspot and energy consumption. There are different stages in MLCEE, first of which is the division of the whole network in layers, the second is clustering of the nodes at same layers. In the last stage of transmission, the cluster head (CH) selects the next hop among the CHs based on greater fitness value, small Hopid and small layer number. To mitigate the issue of hotspot, the first layer remains un-clustered and any node in the first layer transfers data to the sink directly while cluster heads (CHs) are selected based on Bayesian Probability and residual energy. The simulation results of the proposed technique, done using MATLAB, have revealed that MLCEE achieves superior performance than the other techniques with regard to the network lifetime, energy consumption, and data transmission amount.

Modulation of Pulse Train Using Leapfrogging Pulses Developed in Unbalanced Coupled Nonlinear Transmission Lines

The leapfrogging pulses in two unbalanced electrical nonlinear transmission lines (NLTLs) with capacitive couplings are investigated for efficient modulation of a pulse train. Due to the resonant interactions, the nonlinear solitary waves in the NLTLs exhibit complementary behaviors of amplitudes and phases called leapfrogging. For maximizing resonance, both solitary waves should have a common average velocity. Sharing the common velocity, the characteristic impedance can still be freely designed for two coupled solitary waves. In this study, we characterize the leapfrogging pulses developed in unbalanced NLTLs having distinct characteristic impedance. Through the soliton perturbation theory and numerical time-domain calculations, it is found that both the leapfrogging frequency and the voltage variations of pulse amplitudes increase as the difference in the characteristic impedance becomes large. These properties can improve the on/off ratio of modulated pulse train.

Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging.

The unbalanced transmission of chromosomes in human gametes and early preimplantation embryos causes aneuploidy, which is a major cause of infertility and pregnancy failure. A baseline of 20% of human oocytes are estimated to be aneuploid and this increases exponentially from 30 to 35 years, reaching on average 80% by 42 years. As a result, reproductive senescence in human females is predominantly determined by the accelerated decline in genetic quality of oocytes from 30 years of age. Understanding mechanisms of chromosome segregation and aneuploidies in the female germline is a crucial step towards the development of new diagnostic approaches and, possibly, for the development of therapeutic targets and molecules. Here, we have reviewed emerging mechanisms that may drive human aneuploidy, in particular the maternal age effect. We conducted a systematic search in PubMed Central of the primary literature from 1990 through 2016 following the PRISMA guidelines, using MeSH terms related to human aneuploidy. For model organism research, we conducted a literature review based on references in human oocytes manuscripts and general reviews related to chromosome segregation in meiosis and mitosis. Advances in genomic and imaging technologies are allowing unprecedented insight into chromosome segregation in human oocytes. This includes the identification of a novel chromosome segregation error, termed reverse segregation, as well as sister kinetochore configurations that were not predicted based on murine models. Elucidation of mechanisms that result in errors in chromosome segregation in meiosis may lead to therapeutic developments that could improve reproductive outcomes by reducing aneuploidy.

Load growth and power flow control with DSRs: Balanced vs unbalanced transmission networks

An important issue in today’s power system is the need to analyze and determine the adequacy of transmission capacity. There is a need for approaches to increase transmission system capacity without construction of new transmission facilities, all while assuring secure operation of the grid. Distributed Series Reactors (DSRs) are a new smart grid technology that can be applied to control flows in transmission or distribution systems. DSRs can be used to balance phase flows in a single line as well as to control the distribution of flow in a meshed system. This paper investigates DSRs to control power flow to alleviate overloads due to increased power transfer. The IEEE 39 bus standard model is modified to a 3-phase unbalanced transmission model with 345kV lines that accounts for tower geometry. Using the symmetrical components transformation, a balanced, 3-phase model is then derived from the unbalanced, 3-phase model. DSR designs based on the unbalanced, 3-phase model and the balanced, 3-phase model are compared and used to demonstrate the effectiveness of DSR control in handling load growth. Only unbalanced impedances are addressed i.e., non-transposed lines, but the effects of impedance unbalance are shown to be significant on the resulting DSR design.

A Markov Based Performance Analysis of Handover and Load Balancing in HetNets

LTE heterogeneous networks (HetNets) is becoming a popular topic since it was first developed in 3GPP Release 10. HetNets has the advantage to assemble various cell networks and enhance users’ Quality of Service (QoS) within the system. However, its development is still constrained by two main issues: 1) Load imbalance caused by different transmission powers for various tiers, and 2) The unbalanced transmission power may also increase unnecessary handover rate. In order to solve the first issue, Cell range expansion (CRE) can be applied in the system, which will benefit lower-tier cell during user association phase; CRE, Hysteresis Margin (HM) and Time-to-Trigger (TTT) will be utilized to bound UE within lower tier network of HetNets and therefore solve the second issue. On the other hand, the relationship of these parameters may be complicated and even reduce QoS if they are chosen incorrectly. This paper will evaluate the advantage and disadvantage of all three parameters and propose a Markov Chain Process (MCP) based method to find optimal HM, CRE and TTT values. And then, the simulation is taken and the optimal combination for our scenario is obtained to be 1 dB, 6 dB and 60 ms respectively. First contribution of this paper is to map the HetNets handover process into MCP and all the phases of handover can be calculated and analysed in probability way, so that further prediction and simulation can be realised. Second contribution is to establish a mathematical method to model the relationship of HM, CRE and TTT in HetNets, therefore the coordination of these three important parameters is achieved to obtain system optimization.

Nanosecond Pulse Generator Based on an Unbalanced Blumlein-Type Multilayered Microstrip Transmission Line and Solid-State Switches

This paper combines an unbalanced Blumlein-type multilayered microstrip transmission line with solid-state switches to develop a high-voltage nanosecond pulse generator. This study was performed to emphasize the importance of a compact nanosecond pulse generator for biomedical applications. The unbalanced Blumlein-type transmission line reduces current flow through the solid-state switches. A multilayered microstrip transmission line is stacked onto the four-layered printed circuit board to minimize the system volume. Voltage wave propagation analysis is used to explain the principle of the system, which produced a rectangular pulse. The strategy to produce different pulse widths and the controlled timing of the related solid-state switches is interpreted according to this analysis, highlighting the approach needed to achieve a 50–100 ns pulsewidth. Also, the relevant principle of the variable load impedance of the unbalanced Blumlein-type multilayered microstrip transmission line system is also analyzed. To demonstrate the performance of the generator, a miniaturized system is established. Eventually, the nanosecond pulse generator produces a rectangular pulse on a resistor load of 50 $\Omega $ , with amplitude of 0–2 kV, pulsewidth of 50–100 ns, rise time of approximately 20 ns, and repetition frequency of 0 to several kilohertz. Also, when a 500 $\Omega $ resistor is used instead of a 50 $\Omega $ resistor, the output of the nanosecond pulse voltage is approximately two times that of the applied charging voltage.