Abstract Objectives Ultra-sound scan (USS) and Computed Tomography (CT) are commonly used in the diagnosis of acute appendicitis (AA). This audit aims at assessing their sensitivity and implications on the rate of negative appendicectomy (NA) and the number of scans patients have. Methods This is a retrospective multi-centre audit from tertiary (TH) and secondary (SH) hospitals in the United Kingdom. We enrolled patients who underwent appendicectomy over the last year and compared their scans findings to the histopathological findings as the gold standard for AA. Results This is a preliminary report of the first 405 (49.4% females). 69% had USS and 51% had CT scan. USS sensitivity was 57.6%. This sensitivity did not change significantly with age, sex or the size of hospital. CT sensitivity was 95.7%. Females and SH patients tended to have more scans (p< 0.001 for both). 26.4% of the patients had no scans and underwent appendicectomy based on clinical diagnosis. The positive predictive value of this clinical diagnosis was 85% which is equal to USS. 12.1% of the patients had NA, of which 16.4% were females Vs 7.8% males (p= 0.008). The mean age in NA was 26.96 years old Vs 34.12 years old in positive appendicectomy (p=0.009). Conclusion USS sensitivity is low and does not improve in females or younger patients who are also more likely to have NA. Females and SH patients are more likely to have more scans. Findings of USS should be interpreted with care, especially in young and female patients.
Read full abstract