Actual problems of heat exchangers efficiency are considered. It is assumed that the use of ultrasonic vibrations in heat exchangers will help to increase the of heat exchange efficiency, and to reduce the amount of deposits and spume in tube side. Ultrasonic cleaning, as a method of cleaning the surface from solids in washing liquids, in which ultrasonic vibrations are introduced into the liquid in one way or another, is a known technological technique. Application of ultrasound usually significantly speeds up the cleaning process and improves its quality. At the same time, it is possible to replace flammable and toxic solvents with safer detergents without loss of clean- ing quality. Cleaning is due to the combined effect of various non-linear effects arising in the liquid under the influence of powerful ultrasonic vibrations. These effects are cavitation, acoustic currents, sound pressure, sound-capillary effect, among which cavitation plays a decisive role. Pulsating and col- lapsing near contaminants cavitational bubbles destroy them. This effect is known as cavitation erosion. As is known, ultrasonic action leads to a decrease in the viscosity of the medium and, correspondingly, a decrease in the hydraulic resistance, an increase in the flow velocity, which makes it possible to use more viscous media in tube side of heat exchangers. It is also possible to increase the heat transfer due to the internal friction of the molecules of the substance in the ultrasonic field. The passage of ultrasound in media is accompanied by their heating due to the conversion of acoustic energy into thermal energy as a result of ultrasound absorption. The thermal effect is inextricably linked with the mechanical action of ultrasound, since one of the possibilities of heat formation is the conver- sion of mechanical energy into thermal energy as a result of absorption. In the CFX module of the ANSYS software complex, modeling of heat exchange with a change in viscosity was carried out, which is caused by ultrasound effect. The calculations results draw conclusions about the positive effect of ultrasonic oscillations of the medium on heat transfer.