Abstract Aiming at promoting the accuracy of the ultrasonic carotid local pulse wave velocity (LPWV) estimation, an adaptive filtering of pulse waves for the ultrasonic carotid transit time-based LPWV estimation is proposed. First, the upstroke of pulse wave (PWU) is decomposed into time-frequency domain adaptively by an empirical wavelet transform (EWT) method, and then the noises (include the quantization noise and reflected wave in pulse wave) are picked up with predetermined threshold by multiple EWT decompositions. The proposed adaptive filtering of pulse waves for the LPWV estimation is quantitatively evaluated by an ultrasound simulation model for three age groups. Results show that the mean error of EWT-based PWU filtering are just 3.49 %, and the PWV estimation error for the three age groups are 5.77 ± 2.45 %, 4.54 ± 3.46 % and 12.24 ± 5.36 %, respectively by the EWT-based PWU filtering, which is lower than that by SG filtering. The results could be expected to provide theoretical basis and technical support for the early quantitative evaluation of local carotid vascular elasticity in clinic.