Iron Oxide Research Articles

Preparation and Identification of Magnetic Iron Nanoparticle based on a Natural Hydrogel and its Performance in Targeted Drug Delivery

Billions of dollars are spent annually in the world to treat and investigate problems caused by drug side effects. According to the estimates of health researchers, about 40%of people who take medicine suffer from side effects. In this way, the necessity of using a targeted system in order to deliver medicine to the desired place without damaging healthy tissues is felt more than ever. In recent years, targeted drug delivery systems based on nanoparticles have received much attention. Meanwhile, the use of natural polymers is more suitable for various purposes in drug delivery systems in terms of indicating greater biological compatibility with the body and being non-toxic.In this research, the natural hydrogel extracted from the seeds of the Plantago ovata, which is loaded on the bed of magnetic iron nanoparticles, was used to entrap the drugmefenamic acid. In order to achieve this goal, at the beginning, magnetic iron nanoparticles were prepared by co-precipitation method using iron (II) and iron (III) oxides, and then a coating of silica was created on its surface, then the hydrocolloid of Plantago ovata was extracted from its seed, in order to connect the magnetite nanoparticles and the polymer extracted from the Plantago ovata, the surface of both components was modified by vinyl-functional groups. Next, radical polymerization under heat was used to connect the particles and trap the drug, after that the release of the drug from the polymer capsule was checked by UV-Vis device. Before examining the drug release, the resulting product was identified by FT-IR, XRD, VSM, DLS, TGA, SEM analysis. Therefore, the obtained results indicated that the natural polymer was correctly loaded on the desired magnetic substrate and the drug mefenamic acid was trapped inside the hydrogel networks and polymer capsule. Therefore, the drug can be directed in a controlled and targeted manner by the magnetic field, and the release of the drug was done well and at an acceptable speed.

A temporal framework for the Carrapateena Iron Oxide Copper-Gold (IOCG) deposit, Eastern Gawler Craton, South Australia

The Carrapateena Iron Oxide Copper-Gold (IOCG) deposit is located on the eastern margin of the Gawler Craton, approximately ∼475 km NE of Adelaide, South Australia. The deposit is hosted within a granite belonging to the Donington Suite and contains various polylithic breccias and intrusive volcanic units. Multiple stages of alteration/mineralisation are present throughout the deposit, which includes: (1) pre-mineralisation alteration; (2) hematite I; (3) Cu-Au mineralisation; (4) hematite II & REE mineralisation; (5) uranium mineralisation; (6) post-mineralisation alteration/veining. In order to establish a temporal framework, multi-mineral U–Pb geochronology was conducted on a variety of lithologies throughout the deposit and across multiple stages of alteration/mineralisation. Zircons from the host granite are predominantly discordant, with two concordant analyses from two samples producing 207Pb/206Pb ages of ca. 1880–1861 Ma, consistent with the emplacement of the Donington Suite (1860–1850 Ma). Apatite U–Pb geochronology performed on the granite-bearing samples produced ages of ca. 1775–1767 Ma, indicating the presence of a moderate temperature (≥350 °C) thermal event approximately 100 Ma after the crystallisation of the host rock. Zircon U–Pb geochronology conducted on a porphyritic volcanic unit and two polylithic breccia samples produce bi-modal age populations at ca. 1880–1860 Ma & ca. 1590 Ma. The ca. 1880–1860 Ma age reflects zircons inherited from the host granite, while the younger ca. 1590 Ma population represents the crystallisation age of the porphyritic volcanic unit and the maximum formation age of the polylithic breccias. U–Pb geochronology conducted on apatite, hematite and xenotime associated with various stages of mineralisation produce ages of ca. 1585 Ma, consistent with a major Fe-Cu-Au metallogenic event throughout the Gawler Craton. U–Pb geochronology performed on uraninite, apatite located within a late vein, and “vuggy” hematite records a second hydrothermal event from ca. 600–500 Ma, reflecting a period of minor deformation and deposit-wide fluid circulation.

Magnetic Iron Oxide Nanoparticles Coated by Coumarin-Bound Copolymer for Enhanced Magneto- and Photothermal Heating and Luminescent Thermometry

Magnetic Iron Oxide Nanoparticles Coated by Coumarin-Bound Copolymer for Enhanced Magneto- and Photothermal Heating and Luminescent Thermometry

Aspergillus Oryzae Mediated α‐Fe2O3 Nanoparticles for Photocatalytic Remediation of Basic Fuschin Dye and Antimicrobial Activities

AbstractGreen synthetic approach for the synthesis of Iron oxide (α‐Fe2O3) nanoparticles were successfully carried out using Aspergillus oryzae culture mediated biogenic route. The synthesized nanoparticle was confirmed by structural and optical characterization with the help of hematite phase. The α‐Fe2O3 nanoparticles show antimicrobial activity against bacterial strains Staphylococcus aureus, Pseudomonas aeruginosa and fungal strain Candida albicans. Under visible light, the α‐Fe2O3 nanoparticles demonstrate remarkable antibacterial action, confirming their superior efficacy for photocatalytic remediation. The present study discloses that the α‐Fe2O3 nanoparticles are efficient photocatalysts for 96 % degradation of basic fuchsin dye and highly active antimicrobial agent.

Magnetic Iron Oxide Nanomaterials for Lipase Immobilization: Promising Industrial Catalysts for Biodiesel Production

Magnetic Iron Oxide Nanomaterials for Lipase Immobilization: Promising Industrial Catalysts for Biodiesel Production

Insights into the Formation Mechanism of Reactive Oxygen Species in the Interface Reaction of SO2 on Hematite.

The interplay between sulfur and iron holds significant importance in their atmospheric cycle, yet a complete understanding of their coupling mechanism remains elusive. This investigation delves comprehensively into the evolution of reactive oxygen species (ROS) during the interfacial reactions involving sulfur dioxide (SO2) and iron oxides under varying relative humidity conditions. Notably, the direct activation of water by iron oxide was observed to generate a surface hydroxyl radical (•OH). In comparison, the aging of SO2 was found to markedly augment the production of •OH radicals on the surface of α-Fe2O3 under humid conditions. This augmentation was ascribed to the generation of superoxide radicals (•O2-) stemming from the activation of O2 through the Fe(II)/Fe(III) cycle and its combination with the H+ ion to produce hydrogen peroxide (H2O2) on the acidic surface. Moreover, the identification of moderate relative humidity as a pivotal factor in sustaining the surface acidity of iron oxide during SO2 aging underscores its crucial role in the coupling of iron dissolution, ROS production, and SO2 oxidation. Consequently, the interfacial reactions between SO2 and iron oxides under humid conditions are elucidated as atmospheric processes that enhance oxidation capacity rather than deplete ROS. These revelations offer novel insights into the mechanisms underlying •OH radical generation and oxidative potential within atmospheric interfacial chemistry.

Experimental investigation and thermodynamic analysis of application of hybrid nanofluid in a parabolic solar trough collector.

In this research, thermal modeling has been done to investigate the effect of nanofluid on the performance of the linear parabolic collector. Therminol vapor/liquid phase fluid (VP-1) has been used as a base fluid; iron oxide nanoparticles have been used to produce mono-nanofluid; and iron oxide multi-walled carbon nanotubes nanocomposite has been used as nanoparticles to produce hybrid nanofluid. The fluid flow inside the absorber tube of the collector is assumed to be turbulent. The results show that when hybrid nanofluid and mono-nanofluid are used, the energy and exergy efficiencies of the collector are higher than those for the conditions of using the base fluid, but their amount is slightly lower with the use of hybrid nanofluid than when the working fluid is mono-nanofluid. According to the obtained results, the highest energy efficiency of the linear parabolic collector using nanofluid and mono-nanofluid is 70.2% and 70.4%, respectively, and the highest exergy efficiency is 35.7% and 35.9%, respectively. Despite this, the friction coefficient of mono-nanofluid compared to hybrid nanofluid was obtained on average about 9% higher. The results showed that the criterion for evaluating the performance of the collector (hydrodynamic thermal efficiency) when hybrid nanofluid is used is more than when mono-nanofluid is used.

Application of Nanotechnology in Sericulture: A Review

Nanoparticles (NPs) have emerged as promising tools for enhancing mulberry cultivation and the performance of silkworms, crucial for silk production. Mulberry, a vital plant for silk production, demands proper nutrient management for optimal growth and leaf production. Application of NPs, particularly zinc oxide and iron oxide, has shown significant improvements in mulberry growth parameters. Furthermore, NPs have demonstrated positive effects on silkworm larvae, enhancing feed efficiency and growth parameters, leading to better cocoon traits. Silkworms fed with NPs-treated mulberry leaves exhibited increased body weight, cocoon weight, and silk filament characteristics. Additionally, NPs have shown promise in enhancing silkworm reproduction and fecundity while conferring resistance against diseases like BmNPV. Various NPs, including TiO2, silver and chitosan, have exhibited antibacterial properties against silkworm pathogens, thereby contributing to disease prevention. Overall, NPs offer a sustainable and effective approach to enhance mulberry cultivation, improve silkworm performance and mitigate disease risks, thus potentially revolutionizing silk production practices.

Eco-Friendly biogenic synthesis, characterization of Au/Fe3O4 magnetic nanoparticles and its catalytic activity towards degradation of Rhodamine-B

Eco-Friendly biogenic synthesis of gold and iron oxide (Au/Fe3O4) Magnetic nanoparticles (MNPs) using Lepidagathis cristata (LC) leaf extract act as capping and reducing agent. The prepared MNPs was characterized by different analytical techniques such as UV-Vis, FT-IR, XRD, TEM, VSM and BET adsorption-desorption methods. The XRD revealed the formation of LC/Au/Fe3O4 MNPs with crystallite size of about~30 nm. The synthesized LC/Au/Fe3O4 MNPs were found to be ferromagnetic nature, which was confirmed by vibrating sample magnetometer (VSM) at room temperature. Besides, the prepared composite exhibits high specific surface area of 23.6 m2g-1. As well as, the LC/Au/Fe3O4 MNPs showed a good catalytic nature for the degradation of Rhodamine-B (Rh-B) in the presence of Sodium borohydride (NaBH4) in aqueous solution.

Inflammation subsequent to mild iron excess differentially alters regional brain iron metabolism, oxidation and neuroinflammation status in mice

Iron dyshomeostasis and neuroinflammation, characteristic features of the aged brain, and exacerbated in neurodegenerative disease, may induce oxidative stress-mediated neurodegeneration. In this study, the effects of potential priming with mild systemic iron injections on subsequent lipopolysaccharide (LPS)-induced inflammation in adult C57Bl/6J mice were examined. After cognitive testing, regional brain tissues were dissected for iron (metal) measurements by total reflection X-ray fluorescence and synchrotron radiation X-Ray fluorescence-based elemental mapping; and iron regulatory, ferroptosis-related, and glia-specific protein analysis, and lipid peroxidation by western blotting. Microglial morphology and astrogliosis were assessed by immunohistochemistry. Iron only treatment enhanced cognitive performance on the novel object location task compared with iron priming and subsequent LPS-induced inflammation. LPS-induced inflammation, with or without iron treatment, attenuated hippocampal heme oxygenase-1 and augmented 4-hydroxynonenal levels. Conversely, in the cortex, elevated ferritin light chain and xCT (light chain of System Xc−) were observed in response to LPS-induced inflammation, without and with iron-priming. Increased microglial branch/process lengths and astrocyte immunoreactivity were also increased by combined iron and LPS in both the hippocampus and cortex. Here, we demonstrate iron priming and subsequent LPS-induced inflammation led to iron dyshomeostasis, compromised antioxidant function, increased lipid peroxidation and altered neuroinflammatory state in a brain region-dependent manner.

Extraction and Identification of the Essential Oil of Russian knapweed Compounds and their Valorization in Green Synthesis of Iron Oxide Nanoparticles During a Surfactant-free Nano-emulsions System

Extraction and Identification of the Essential Oil of Russian knapweed Compounds and their Valorization in Green Synthesis of Iron Oxide Nanoparticles During a Surfactant-free Nano-emulsions System

Numerical study on the internal ventilation of the engine room of a ship under construction

Manual welding operations are performed inside the engine room of a liquefied natural gas carrier under construction. The welders are at risk of exposure to welding fumes in case of poor ventilation. Therefore, ventilation fans are installed at shipbuilding sites to improve indoor air quality. Although ensuring the respiratory health of welders is important, studies focusing on ventilation in the ship engine room have not been conducted. Therefore, the ventilation efficiency was evaluated herein based on the placement of ventilation fans to alleviate air stagnation using a computational fluid dynamic (CFD) model operating on Fluent. The mean age of air (MAA) was computed to assess the ventilation efficiency. In addition, particles with size and physical properties similar to welding fumes were sourced assuming 30 welders in the engine room. Results revealed that ventilation fan and/or exhaust in enclosed spaces contributes significantly to alleviating the MAA level. MAA and particle distribution did not correlate well due to the different properties of air and the iron oxide particle. Therefore, to determine the optimal ventilation fan displacement, particle motion should be studied along with performing MAA analysis. The proposed CFD model potentially guides to improvement of the working environments and respiratory health of welders.

Exploring the Limits of Fe-Rich Chemistries in Na-Based CaFe2O4-Type Postspinel Oxides.

Structural trends, physical properties, and electrochemical performances of the NaFexRu2-xO4 system have been investigated. Synthesis attempts using both conventional solid-state routes and high-pressure methods were explored for the compositional range 1.0 ≤ x ≤ 1.67. Based on Rietveld refinements against powder X-ray diffraction data, analyses of 57Fe Mössbauer spectroscopy data, and elemental analysis by electron microprobe, the existence of a confined compositional solid solution (1 ≤ x ≤ 1.3) adopting the CaFe2O4-type postspinel structure is demonstrated. This is contrasted with the NaFexTi2-xO4 system, for which no evidence of a solid solution is observed. However, for all explored synthetic routes of NaFexRu2-xO4 compositions, a trivalent iron oxidation state is maintained. Structural analysis and qualitative bond valence energy landscape models reveal that the progressive integration of iron into the postspinel framework results in narrowed sodium ion diffusion channels, restricting electrochemical deintercalation of sodium. Consequently, the CaFe2O4-type iron-rich compounds explored in this study demonstrate limited potential as positive electrode materials for sodium batteries. It is expected that this fundamental insight will help guide the exploration of alternative NaM2O4-based positive electrode materials with similar structure types.

Cu1‐Fe Dual Sites for Superior Neutral Ammonia Electrosynthesis from Nitrate

The electrochemical nitrate reduction reaction (NO3RR) is able to convert nitrate (NO3‐) into reusable ammonia (NH3), offering a green treatment and resource utilization strategy of nitrate wastewater and ammonia synthesis. The conversion of NO3‐ to NH3 undergoes water dissociation to generate active hydrogen atoms and nitrogen‐containing intermediates hydrogenation tandemly. The two relay processes compete for the same active sites, especially under pH‐neutral condition, resulting in the suboptimal efficiency and selectivity in the electrosynthesis of NH3 from NO3‐. Herein, we constructed a Cu1‐Fe dual‐site catalyst by anchoring Cu single atoms on amorphous iron oxide shell of nanoscale zero‐valent iron (nZVI) for the electrochemical NO3RR, achieving an impressive NO3‐ removal efficiency of 94.8% and NH3 selectivity of 99.2% under neutral pH and nitrate concentration of 50 mg L‐1 NO3‐‐N conditions, greatly surpassing the performance of nZVI counterpart. This superior performance can be attributed to the synergistic effect of enhanced NO3‐ adsorption on Fe sites and strengthened water activation on single‐atom Cu sites, decreasing the energy barrier for the rate‐determining step of *NO‐to‐*NOH. This work develops a novel strategy of fabricating dual‐site catalysts to enhance the electrosynthesis of NH3 from NO3‐, and presents an environmentally sustainable approach for neutral nitrate wastewater treatment.

Thermomagnetic analysis applied for identification of lithogenic and pedogenic iron oxides in topsoils from Bulgaria

Identification of magnetic minerals, which determine the magnetic properties of natural rocks, sediments and soils, is of crucial importance for any further interpretation of their magnetic signature in environmental or paleogeographical context. One of the major and widely used methods for determination of kind of magnetic phases in natural materials is by obtaining the Curie/Neel temperature of the respective magnetic mineral. In this contribution, we report a set of thermomagnetic measurements of high-temperature behavior of magnetic susceptibility for topsoils from the territory of Bulgaria, aiming to reveal the pedogenic and lithogenic signature. The data are considered and reported in respect to the parent rock type. Our results suggest that pedogenic magnetic minerals are represented mainly by fine-grained maghemite and/or hematite with possible Al-substitutions in the crystal lattice. This phase is expressed on the heating run of the thermomagnetic curve as a “hump” with a maximum at 250–300 °C. Coarse-grained magnetite is identified as a dominant lithogenic magnetic mineral. Hematite’s presence in a sub-set of red-colored soils is confirmed by additional analyses of isothermal remanence acquisition curves. Two hematite coercivity components were identified, related to pedogenic and lithogenic origin, respectively.

Cu1-Fe Dual Sites for Superior Neutral Ammonia Electrosynthesis from Nitrate.

The electrochemical nitrate reduction reaction (NO3RR) is able to convert nitrate (NO3-) into reusable ammonia (NH3), offering a green treatment and resource utilization strategy of nitrate wastewater and ammonia synthesis. The conversion of NO3- to NH3 undergoes water dissociation to generate active hydrogen atoms and nitrogen-containing intermediates hydrogenation tandemly. The two relay processes compete for the same active sites, especially under pH-neutral condition, resulting in the suboptimal efficiency and selectivity in the electrosynthesis of NH3 from NO3-. Herein, we constructed a Cu1-Fe dual-site catalyst by anchoring Cu single atoms on amorphous iron oxide shell of nanoscale zero-valent iron (nZVI) for the electrochemical NO3RR, achieving an impressive NO3- removal efficiency of 94.8% and NH3 selectivity of 99.2% under neutral pH and nitrate concentration of 50 mg L-1 NO3--N conditions, greatly surpassing the performance of nZVI counterpart. This superior performance can be attributed to the synergistic effect of enhanced NO3- adsorption on Fe sites and strengthened water activation on single-atom Cu sites, decreasing the energy barrier for the rate-determining step of *NO-to-*NOH. This work develops a novel strategy of fabricating dual-site catalysts to enhance the electrosynthesis of NH3 from NO3-, and presents an environmentally sustainable approach for neutral nitrate wastewater treatment.

Controlling the Magnetic Responsiveness of Cellulose Nanofiber Particles Embedded with Iron Oxide Nanoparticles.

2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-oxidized cellulose nanofiber (TOCN) particles, an innovative biobased material derived from wood biomass, have garnered significant interest, particularly in the biomedical field, for their distinctive properties as biocompatible particle adsorbents. However, their microscopic size complicates their separation in liquid media, thereby impeding their application in various domains. In this study, superparamagnetic magnetite nanoparticles (NPs), specifically iron oxide Fe3O4 NPs with an average size of 15 nm, were used to enhance the collection efficiency of TOCN-Fe3O4 composite particles synthesized through spray drying. These composite particles exhibited a remarkable ζ-potential (approximately -50 mV), indicating their high stability in water, as well as impressive magnetization properties (up to 47 emu/g), and rapid magnetic responsiveness within 60 s in water (3 wt % Fe3O4 to TOCN, 1 T magnet). Furthermore, the influence of Fe3O4 NP concentrations on the measurement of the speed of magnetic separation was quantitatively discussed. Additionally, the binding affinity of the synthesized particles for proteins was assessed on a streptavidin-biotin binding system, offering crucial insights into their binding capabilities with specific proteins and underscoring their significant potential as functionalized biomedical materials.

Efficient Strategy to Synthesize Tunable pH-Responsive Hybrid Micelles Based on Iron Oxide and Gold Nanoparticles.

The preparation of multifunctional nanomaterials based on inorganic nanoparticles with organic materials has emerged as a promising strategy for the development of new nanomedicines for in vitro and in vivo biomedical applications. Here, we synthesized pH-responsive hybrid inorganic micelles by combining a novel pH-responsive amphiphilic molecule with hydrophobic payloads. This amphiphile was synthesized in a one-pot reaction and self-assembled readily into micelles under acidic pH conditions. In the presence of hydrophobic NP payloads such as AuNPs or IONPs, the amphiphile self-organized around them through hydrophobic interactions, resulting in the formation of colloidally stable hybrid micelles. The size of the hydrophobic NPs determined the pH-response of the inorganic hybrid micelles, which is tuned from pH 7 to 11 for our pH-responsive amphiphilic molecule. This achievement represents a novel approach for the synthesis of tunable pH-responsive hybrid micelles based on inorganic NPs for biomedical imaging, hyperthermia treatment, and also drug delivery nanosystems.

Irradiation-assisted synthesis of smart hydrogels based on nanomagnetic semi-interpenetrating p(HEMA)/PVP networks for the cleaning of cultural heritage artifacts

Preservation of our cultural and historical heritage as a testimony to our shared past is a responsibility that demands significant attention. One of the most critical and delicate aspects of conserving such treasures is cleaning them safely and effectively. Chemical hydrogels specifically designed for cleaning cultural heritage artifacts allow for the containment and controlled release of water. Based on a generic approach, a smart nanomagnetic hydrogel was developed using a semi-interpenetrating polymer network (semi-IPN) of polyhydroxyethyl methacrylate (p(HEMA)) and polyvinyl pyrrolidone (PVP). Gamma irradiation was employed to perform simultaneous in-situ polymerization, crosslinking, and also immobilization of iron oxide magnetic nanoparticles (MNPs). The chemical and structural characteristics of the nanomagnetic hydrogel were investigated using gel content, equilibrium water content, field-emission scanning electron microscopy, magnetic properties, compressive strength, dehydration kinetics, and adhesion tests. The optimal formula for smart hydrogel was a ratio of monomer to polymer 50:50, a water content of 60 wt.%, a gamma radiation dose of 20 kGy, and 3 wt.% of MNP. Two cotton canvas case studies demonstrate the versatility and effectiveness of the selected hydrogel in removing dirt and confining the water-based cleaning system. It was found that no color leaching occurred during the cleaning process.

Optimization of Biodiesel Production Process Using MoO3 Catalysts and Residual Oil: A Comprehensive Experimental 23 Study.

The study aimed to utilize MoO3 catalysts, produced on a pilot scale via combustion reaction, to produce biodiesel from residual oil. Optimization of the process was conducted using a 23 experimental design. Structural characterization of the catalysts was performed through X-ray diffraction, fluorescence, Raman spectroscopy, and particle size distribution analyses. At the same time, thermal properties were examined via thermogravimetry and differential thermal analysis. Catalytic performance was assessed following process optimization. α-MoO3 exhibited a monophasic structure with orthorhombic phase, whereas α/h-MoO3 showed a biphasic structure. α-MoO3 had a larger crystallite size and higher crystallinity, with thermal stability observed up to certain temperatures. X-ray fluorescence confirmed molybdenum oxide predominance in the catalysts, with traces of iron oxide. Particle size distribution analyses revealed polymodal distributions attributed to structural differences. Both catalysts demonstrated activity under all conditions tested, with ester conversions ranging from 93% to 99%. The single-phase catalyst had a long life cycle and was reusable for six biodiesel production cycles. The experimental design proved to be predictive and significant, with the type of catalyst being the most influential variable. Optimal conditions included α-MoO3 catalyst, oil/alcohol ratio of 1/15, and a reaction time of 60 min, resulting in high biodiesel conversion rates and showcasing the viability of MoO3 catalysts in residual oil biodiesel production.