AbstractThe practical utilization of Li metal anodes has been significantly plagued by the challenges of uncontrollable dendritic Li growth and poor interphase instability. Here, the study reports a novel strategy to strengthen interphase and give highly efficient active seeds concurrently to stabilize Li metal via a highly lithiophilic In2O3 decorated porous scaffold. In situ configurated fast‐ion‐transport Li2O‐strengthened interphase layer cooperatively with highly efficient Li13In3 nucleation induction can endow the uniform Li nucleation/growth and high Li utilization efficiency. As a result, the achieved modified Li metal manifests high Coulombic efficiency, ultrahigh rate performance (5 mA cm−2), and ultra‐long lifespan cycling durability (7975 cycles). Importantly, the established Li|LiFePO4 cells exhibit long‐term cycling durability over 600 cycles at 1 C with an ultralow decay rate of ca. 0.017% per cycle. Moreover, the Li|LiCoO2 pouch cells with ultrahigh areal capacity of ca. 3.89 mAh cm−2 also exhibit extraordinarily prolonged cycling performance with excellent capacity retention despite extremely harsh cycling conditions of low negative‐to‐positive‐capacity (N/P) ratio of ca. 1.7 and lean electrolyte of ca. 4.9 g Ah−1. This work enlightens a facile and effective avenue toward highly stable Li metal anode toward reliable practicability.