Abstract In this paper, influence of typical turbulent flow field on a multi-channel ultrasonic flowmeter was studied. Experimental sample of the cross four-channel ultrasonic flowmeter were designed and processed, and CFD simulation models of flowmeter and right-handed spoiler, gate valve and velocity profile spoiler were established. Through simulation, the turbulent flow field behind typical spoilers such as right-handed spoiler, gate valve and velocity profile spoiler, and the influence of turbulent flow field on the metering performance of the cross four-channel ultrasonic flowmeter were studied. On this basis, the CFD simulation results and the real flow experiment results were compared and analyzed, and the reliability of the CFD simulation analysis results was verified, which provides the research basis for improving flowmeter performance.