Gaining knowledge about vegetation sensitivity in response to climate change is a current research priority in the context of accelerated shifts generated by global warming, especially for the Qinghai–Tibet Plateau (QTP), where vegetation is known to be highly sensitive to ongoing climate change. However, the temporal variability of vegetation sensitivity in response to climate change is still poorly understood on the QTP. Here, we articulate the interannual variability of the vegetation sensitivity in response to typical climate factors, including temperature, solar radiation, and water availability, on the QTP during 2000–2021, using a variety of indicators characterizing vegetation dynamics, including the Leaf Area Index (LAI), the Normalized Difference Vegetation Index (NDVI), the Enhanced Vegetation Index (EVI), and solar-induced chlorophyll fluorescence (SIF) data. The results indicate that temperature exerted positive impacts on forests, grasslands, and barren or sparsely vegetated areas (BSVs). However, all the land-cover types showed decreasing sensitivity to temperature variability. Solar radiation had a positive impact on forests, while it had a negative impact on grasslands and BSVs. An increasing trend was observed for forests, while a decreasing trend was found for grasslands and BSVs regarding their sensitivity to solar radiation. Water availability exerted a positive impact on grasslands and BSVs, and no obvious impact direction could be determined for forests. Over the last two decades, forests and BSVs exhibited increasing sensitivity to water availability, and no obvious trend was observed for grasslands. Overall, temperature was the most important climate factor, followed by solar radiation and water availability, regarding the regulation of vegetation sensitivity on the QTP. Spatially, temperature and solar radiation jointly dominated the vegetation sensitivity in the central to eastern QTP. Conversely, water availability dominated the sensitivity of forests in the southeastern QTP and grasslands in the northeastern and southwestern QTP. This study provides theoretical support for the ecological conservation and management of the QTP in the context of ongoing climate change.
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