Types Of Motion Research Articles

Disrupted microsaccade responses in late-life depression

Late-life depression (LLD) is a psychiatric disorder in older adults, characterized by high prevalence and significant mortality rates. Thus, it is imperative to develop objective and cost-effective methods for detecting LLD. Individuals with depression often exhibit disrupted levels of arousal, and microsaccades, as a type of fixational eye movement that can be measured non-invasively, are known to be modulated by arousal. This makes microsaccades a promising candidate as biomarkers for LLD. In this study, we used a high-resolution, video-based eye-tracker to examine microsaccade behavior in a visual fixation task between LLD patients and age-matched healthy controls (CTRL). Our goal was to determine whether microsaccade responses are disrupted in LLD compared to CTRL. LLD patients exhibited significantly higher microsaccade peak velocities and larger amplitudes compared to CTRL. Although microsaccade rates were lower in LLD than in CTRL, these differences were not statistically significant. Additionally, while both groups displayed microsaccadic inhibition and rebound in response to changes in background luminance, this modulation was significantly blunted in LLD patients, suggesting dysfunction in the neural circuits responsible for microsaccade generation. Together, these findings, for the first time, demonstrate significant alterations in microsaccade behavior in LLD patients compared to CTRL, highlighting the potential of these disrupted responses as behavioral biomarkers for identifying individuals at risk for LLD.

Using consumer wearables to estimate physical activity of nursing home residents with dementia

Aim: Physical activity of nursing home residents can be assessed with tools such as questionnaires and standardized fitness tests. For residents with dementia, however, those tools can be cognitively challenging and difficult to administer. Consumer wearables could potentially aid as an affordable tool for ubiquitous assessment. Methods: In this pilot study with 16 participants, we explored how measurements with an off-the-shelf wearable relate to structured observations of physical activity. We collected both processed and raw tri-axial accelerometer data from Samsung wrist-worn fitness trackers. To anchor those data in the free-living environment, we compared the measurements with the physical activity scale of the Medlo behavioral observation scheme. Results: We showed that consumer wearables are a valid tool for long-term data collection in this vulnerable patient population. Conclusions: Regarding the movement intensity, the data collected by fitness trackers is overall in accordance with the data collected with the observational tool. Regarding the type of movement, we concluded that the automatic activity classification on the wearables is not yet ready for use with a mostly sedentary patient population.

Practical implementation of parmetric identification of linear mathematical models of marine vessels by tables of maneuvering elements

The paper considers the practical implementation of the algorithm for identifying the parameters of linear mathematical models of Nomoto 1st and 2nd order of the marine vessels based on experimental data. Information from the maneuvering element tables containing information on the vessel’s circulation is used as experimental data. The initial data are presented in the form of discrete sampling, which allows obtaining the model parameters in a discrete form and then making the transition to a continuous form. The initial data are formed for each type of motion: a loaded vessel, a vessel in ballast, half-board and aboard, starboard and port aboard. The paper uses a method for determining the parameters of the transfer functions of the obtained models using the least squares method for transient characteristics. To improve the quality of the assessment of the parameters of the identified model, it is proposed to interpolate the initial data. The following methods are used in the paper: linear interpolation, interpolation by adjacent points, cubic and spline interpolation. To implement the proposed method, a program has been developed and implemented in the MatLab environment, which allows interpolation of the transient response by a method selected from the proposed ones, and then, based on the interpolated values, to determine the parameters of the transfer function. A block diagram and description of the algorithm for the operation of this program are provided. The result of its operation is a model with its own parameters for each case of vessel motion. The program displays graphs of transient processes for the initial data and calculated ones for each selected type of interpolation, and also displays the parameters of the transfer functions of the models. A description of the source data file used is provided. To assess the quality of software-implemented identification models, a model circulation trajectory is calculated and its graphic construction occurs. As a result of the program, the obtained linear mathematical models are proposed to be grouped and presented in interval form.

Conformational Dynamics of Mitochondrial Inorganic Pyrophosphatase hPPA2 and Its Changes Caused by Pathogenic Mutations.

Inorganic pyrophosphatases, or PPases, are ubiquitous enzymes whose activity is necessary for a large number of biosynthetic reactions. The catalytic function of PPases is dependent on certain conformational changes that have been previously characterized based on the comparison of the crystal structures of various complexes. The current work describes the conformational dynamics of a structural model of human mitochondrial pyrophosphatase hPPA2 using molecular dynamics simulation, all-atom principal component analysis, and coarse-grained normal mode analysis. In addition to the wild-type enzyme, four mutant variants of hPPA2 were characterized that correspond to the natural pathogenic variants causing severe mitochondrial dysfunction and cardio pathologies. As a result, we identified the global type of flexible motion that seems to be shared by other dimeric PPases. This motion is discussed in terms of the allosteric behavior of the protein. Analysis of the observed conformational dynamics revealed the formation of a binding site for anionic ligands in the active site that could be relevant to enzyme catalysis. Based on the comparison of the wild-type and mutant PPases dynamics, we suggest the possible molecular mechanisms of the functional incompetence of hPPA2 caused by mutations. The results of this work allow for deeper insight into the structural basis of PPase function and the possible effects of pathogenic mutations on the protein structure and function.

Early effectiveness of navigation-free robot-assisted total knee arthroplasty in treating knee osteoarthritis with extra-articular deformities

To evaluate the early effectiveness of navigation-free robot-assisted total knee arthroplasty (TKA) compared to traditional TKA in the treatment of knee osteoarthritis combined with extra-articular deformities. The clinical data of 30 patients with knee osteoarthritis combined with extra-articular deformities who met the selection criteria between June 2019 and January 2024 were retrospectively analyzed. Fifteen patients underwent CORI navigation-free robot-assisted TKA and intra-articular osteotomy (robot group) and 15 patients underwent traditional TKA and intra-articular osteotomy (traditional group). There was no significant difference in age, gender, body mass index, affected knee side, extra-articular deformity angle, deformity position, deformity type, and preoperative knee range of motion, American Knee Society (KSS) knee score and KSS function score, and lower limb alignment deviation between the two groups ( P>0.05). The operation time, intraoperative blood loss, and complications of the two groups were recorded and compared. The knee range of motion and lower limb alignment deviation were recorded before operation and at 6 months after operation, and the knee joint function was evaluated by KSS knee score and function score. There was no significant difference in operation time between the two groups ( P>0.05); the intraoperative blood loss in the robot group was significantly less than that in the traditional group ( P<0.05). Patients in both groups were followed up 6-12 months, with an average of 8.7 months. The incisions of all patients healed well, and there was no postoperative complication such as thrombosis or infection. At 6 months after operation, X-ray examination showed that the position of the prosthesis was good in both groups, and there was no loosening or dislocation of the prosthesis. The knee joint range of motion, the lower limb alignment deviation, and the KSS knee score and KSS function score significantly improved in both groups ( P<0.05) compared to preoperative ones. The changes of lower limb alignment deviation and KSS function score between pre- and post-operation in the robot group were significantly better than those in the traditional group ( P<0.05), while the changes of other indicators between pre- and post-operation in the two groups were not significant ( P>0.05). Compared to traditional TKA, navigation-free robot-assisted TKA for knee osteoarthritis with extra-articular deformities results in less intraoperative blood loss, more precise reconstruction of lower limb alignment, and better early effectiveness. However, long-term effectiveness require further investigation.

Physical activity patterns following major lower limb amputation

Introduction and aim of study: Lower limb amputation is one of the most common acquired disabilities. The main aim of the study was to assess global trends regarding the procedure, investigate the current trends in post-amputation care, particularly in terms of returning to physical fitness, and identify potential fields of interest in order to improve the everyday life of people with lower limb amputation. Materials and methods: The authors based this review paper on a widespread analysis of scientific articles published in Science Direct, PubMed, UpToDate, Cochrane, Springer, and Google Scholar, the 2021 Global Burden of Disease Study, and government platforms. Results: The collected information emphasizes the existence of numerous barriers discouraging from participating in sports. The post-amputation care is crucial and requires a multidisciplinary team approach. Chronic pain restricts physical activity significantly. Different types of movement focused on specific muscle groups improve functionality. Conclusions: Disability as a result of lower limb amputation is a significant social issue requiring more action to improve its visibility. New strategies ought to be implemented to educate people with disabilities on the importance of physical activity. The new technologies that are currently under investigation may bring some novelty to the topic in the future. Keywords: Amputation, Artificial limbs, Rehabilitation, Para-Sports

Lateral End-Range Movement Profile and Shot Effectiveness During Grand Slam Tennis Match-Play.

End-range movements are among the most demanding but least understood in the sport of tennis. Using male Hawk-Eye data from match-play during the 2021-2023 Australian Open tournaments, we evaluated the speed, deceleration, acceleration, and shot quality characteristics of these types of movement in men's Grand Slam tennis. Lateral end-range movements that incorporated a change of direction (CoD) were identified for analysis using k-means (end-range) and random forest (CoD) machine learning models. Peak speed, average deceleration into the CoD, average reacceleration out of the CoD, and the quality of the shot played were computed. Players were grouped based on their ATP rankings (top 10, top 50, and outside top 50) to examine the influence of ranking on movement profiles and shot effectiveness. Our data showed that end-range movements profiles of top 10 and top 50 players were characterized by higher peak speed (d=0.3-0.88), deceleration intensity (d=0.25-0.63), and acceleration intensity (d=0.06-0.51) when compared to players outside the top 50 (p<0.05). Top 10 players also demonstrated greater peak speeds (d=0.59) and acceleration intensities (d=0.45) compared to top 50 players (p<0.05). There was a nonlinear inverse relationship between peak speed and shot quality, such that, as peak speed increased, shot quality decreased-notwithstanding that top 10 players were more likely to hit high-quality shots at higher peak speeds. These results quantify the discrete kinematic characteristics of the sport's most challenging movement sequence and reveal, for the first time, that higher ranked players may possess superior movement potential on court.

Orthodontic treatment for preserving periodontally hopeless teeth in a middle-aged patient: a case report.

In this case report, we show a strategic approach to prolonging the lifespan of pathologically migrated maxillary canines with a hopeless prognosis in a 57-year-old female patient, highlighting the potential of orthodontic management for middle-aged patients to enhance both occlusion and facial esthetics while minimizing the need for extensive prosthetic treatment. According to the visual treatment objective, the nonextraction treatment plan showed advantages in the type of orthodontic tooth movement and final occlusal relationship. Therefore, considering the favorable periodontal treatment results and single-root teeth, the hopelessly migrated maxillary canines were relocated, eliminating the existing trauma from occlusion. Segmental tooth movement was performed, and orthodontic temporary skeletal anchorage devices were used to support strategic orthodontic tooth movement. After 27 months of treatment, proper occlusion was established with a significant improvement in facial esthetics. The periodontally compromised teeth were preserved with adequate periodontal support. The patient expressed satisfaction with the results, and the 30-month follow-up records confirmed the stability of treatment outcomes.

Subsets of extraocular motoneurons produce kinematically distinct saccades during hunting and exploration.

Animals construct diverse behavioral repertoires by moving a limited number of body parts with varied kinematics and patterns of coordination. There is evidence that distinct movements can be generated by changes in activity dynamics within a common pool of motoneurons or by selectively engaging specific subsets of motoneurons in a task-dependent manner. However, in most cases, we have an incomplete understanding of the patterns of motoneuron activity that generate distinct actions and of how upstream premotor circuits select and assemble such motor programs. In this study, we used two closely related but kinematically distinct types of saccadic eye movement in larval zebrafish as a model to examine circuit control of movement diversity. In contrast to the prevailing view of a final common pathway, we found that in the oculomotor nucleus, distinct subsets of motoneurons were engaged for each saccade type. This type-specific recruitment was topographically organized and aligned with ultrastructural differences in motoneuron morphology and afferent synaptic innervation. Medially located motoneurons were active for both saccade types, and circuit tracing revealed a type-agnostic premotor pathway that appears to control their recruitment. By contrast, a laterally located subset of motoneurons was specifically active for hunting-associated saccades and received premotor input from pretectal hunting command neurons. Our data support a model in which generalist and action-specific premotor pathways engage distinct subsets of motoneurons to elicit varied movements of the same body part that subserve distinct behavioral functions.

Spatial Movement With Explicit Memory and Nonlocal Pregnancy Delay

ABSTRACTIn depicting animal movement, besides considering spatial memory, the pregnancy period of the animals themselves should also be taken into account. This article proposes a novel single‐population model with discrete memory delay and nonlocal spatiotemporal gestation delay. Assuming the positive equilibrium is locally stable without spatiotemporal delay, the study investigates two types of directional movements using memory delay and gestation delay as control parameters. The research shows that for the positive memory‐based diffusion coefficient, the system destabilizes through homogeneous/nonhomogeneous Hopf bifurcations, but for the negative memory diffusion coefficient, the system not only undergo Hopf bifurcations but also becomes unstable through Turing bifurcations, and may even exhibit Turing–Hopf bifurcation. Finally, we use a diffusive logistic model with predation behavior as an example to numerically simulate the theoretical results and also discover stability switch phenomena.

대한민국 상해 임시정부 경찰의 역할에 관한 연구 - 독립운동 유형을 중심으로

The 「Provisional Government of the Republic of Korea」 promulgated the 「Provisional Government of the Republic of Korea」 on April 25, 1919 and the Provisional Control of the Republic of Korea in November, forming the organization of the Provisional President and the State Council. The 「Provisional Government of the Republic of Korea」 became the cornerstone of the establishment of the police bureau to announce the departure of the police, and although it was changed according to the pending issues of the provisional government, it remained a police agency of the provisional government until August 1945. According to data from the National Police Agency in korea, the Provisional Government of the Republic of Korea in Shanghai, China, established the beginning of the police organization as a police bureau immediately afrer its establishment. This study aims to examine the historical implications of today's police forces and types of independence movements based on the Provisional Government of the Republic of Shanghai. It also aims to examine the historical changes of the police and to illuminate the primary purpose of the independence movement in the provisional government. The functions and roles of police in the independence movement during the Shanghai Provisional Government are largely divided into three types. First, it shows the function and type of intelligence police that defend various types of information and search for traffickers in order to protect the provisional government from Japanese(倭) and the safety of factors that campaign for independence. Second, it is a communication system Third, it is the police unit. From the history of the police during the Shanghai Provisional Government to the present role of the police should inherit the police spirit for the Shanghai Provisional Government Independence Movement in order to grow into a memorable organization from the people in the future.

Durability Capacity of Women Cultivators Under Pressure of Forest and Land Fire Control Regulation in Central Kalimantan, Indonesia

This study aims to explore the conditions of pressure and durability capacity of women cultivators facing the pressures of regulation on forest and land fire control in Indonesia. The results of this study highlight that the scientific knowledge and patriarchal capitalism perspective contribute to product regulation in Indonesia, and then creating women cultivators as a non-class subjects. Thus, the woman cultivators are victims of that regulation. Women cultivators have various complex strategies and adaptations in dealing with multiple pressures under regulations on one site, corporations and food estate programs on other sites. The act of burning fields is not intended to fight the rules, but an act with no alternatives for survival from the lowest view. The act of burning is an act of utilizing the capacity to produce and reproduce the capacity of remaining food sources and the capacity for subsistence independence. Understanding the act of burning fields by Oloh Ngaju women cultivators is an effort to understand the farming activities as rationalized by individual actions within the limits of their interests and limit power (setting the limits to domination). So it is very possible to propose the concept of subsistence feminism to see the type of the grassroots women's movement.

A principled exception to the Müller-Takano Generalization: A belated follow-up to Richards (2004)

According to the Müller-Takano Generalization (Müller 1993; Takano 1994), a remnant that contains a trace resulting from a given type of movement cannot itself undergo that same type of movement. I argue that Richards’ (2004) data from Bulgarian “Russian-doll” wh-questions constitute principled exceptions to this generalization under an approach that derives it from a minimality condition on movement paths. Alternative approaches to the generalization have a harder time deriving such exceptions.

PHANTOM CHAINS TONTOR OF BIONIC OBJECT'S MOVEMENTS OF AUTOMATED SYSTEMS. Part 2

In our previous author’s works such properties of the phantom step as its length and curvature relative to the imaginary plane were considered. All these parameters were considered within clearly defined coordinates associated with the beginning and end of the step. Analytical and graphical models were obtained in this work, which are based on mathematical approaches to determining the spatiotemporal characteristics of the movement of objects taking into account the characteristics of phantom chains of bionic systems. Therefore, the application of the obtained models provides prospects for obtaining precise parameters of the movement of the final real technological object in the working space when performing complex kinematics of movements. At the same time, the dependences of the relationship between the volumes of technological abstract and their formed phantoms were investigated, which provide the opportunity to describe positive and negative technologies that are currently promising in modern production and the realities of the application of bionic automated equipment for various purposes. The results of our research can be used as a basis for obtaining new analytical models that determine the motion characteristics of dynamic abstract objects depending on the scope of application. This has the ultimate goal of being able to determine different types of motion of bionic objects, which is associated with automated systems in industry, medicine, implementation of technological processes, and scientific research. The prospects for further scientific research on this problem regarding the development of bionic automated systems, devices and objects are to continue the creation of analytical models of these objects with a view to their application in various areas and at different stages of the life cycle of technological objects, which improves production processes, as well as complex bionic systems for medical purposes.

Метод предсказания глазодвигательной активности на основе интеллектуального анализа данных мобильного портативного электроэнцефалографа

Eye movement processes, such as fixations and saccades, play a crucial role in human cognitive activity as they are closely associated with functions such as perception, attention, and decision-making. These processes are actively applied in various fields, including human-computer interaction systems and neurophysiological research. Modern eye-tracking methods based on optical systems provide high accuracy but have several significant limitations. In this regard, the use of electroencephalographic (EEG) data for analyzing eye movement activity is becoming a promising direction, as EEG provides insights into the neural processes underlying eye movements. This allows many limitations of optical systems to be overcome, enabling the monitoring of eye movements without direct visual tracking. The goal of this study is to develop a method for predicting eye movement activity based on data collected from the BrainBit mobile EEG device. The study utilizes a long short-term memory (LSTM) neural network. Experimental results demonstrated that the proposed model achieves high accuracy in classifying the main types of eye movement activity. For fixations and saccades, the classification accuracy reached 91?%, indicating a high effectiveness of the model for these types of movements. However, classifying directed eye movements, such as left/right and up/down movements, proved to be a more challenging task, with an accuracy of about 65?% and 63?%, respectively. One of the key challenges identified in the study was the high individual variability of EEG signals between participants. As a result, the model training was personalized for each participant, which improved the accuracy of predictions for each individual. Thus, the study highlights the potential of using EEG for analyzing and predicting eye movements, particularly in the context of fixations and saccades.

Experimental Study of the Kinematics of a Double-Row Planetary Mechanism Using Two Elliptical External Gears

Introduction. Mechanisms with non-circular gears are of wide interest to researchers and inventors due to their compactness and the implementation of a wide range of transfer functions. The development of this area is stimulated by the advancements and reduction in cost of mechanical processing and additive manufacturing technologies, as well as the use of applied mathematical modeling packages for the analysis and synthesis of non-circular gears. Traditionally, noncircular gears are used to transmit rotational motion between parallel axes with a variable ratio of angular velocities. However, their use in planetary gear schemes provides implementing various types of output link motion. The analysis of the papers on the research area shows that gears with movable rotation axes have not been sufficiently studied from the point of view of kinematics and dynamics. Most research papers reveal the theory of such mechanisms without verifying the results obtained in practice. This work is aimed at the experimental verification of the kinematics of a planetary mechanism with two external engagements, which contains elliptical gears.Materials and Methods. The kinematic model of the mechanism under study is built on the basis of the velocity diagram of its links, which made it possible to obtain expressions for finding an analogue of the angular velocity and the position function of the output shaft. The experimental study of kinematics was performed on a laboratory stand containing a model of a planetary mechanism with a set of replaceable gear wheels, absolute encoders on the input and output shafts of the mechanism, a controller, and a PC for recording and processing the signal. The analysis of the obtained results was performed on a computer using statistical analysis methods.Results. As a result of kinematic analysis, position functions were constructed for three alternative planetary mechanisms, which had different geometric parameters of the gears and made it possible to implement various types of motion of the output shaft: swinging motion, discontinuous motion, and unilateral uneven rotation.Discussion and Conclusion. The analysis of the experimental results showed the adequacy of the constructed mathematical model of kinematics to real mechanisms. The confidence interval of measuring errors at a reliability level of 95% was 0.16±0.08° for the first version of the mechanism, 0.57±0.22° — for the second version, and 0.08±0.26° — for the third. The proposed planetary mechanism with elliptical gears for implementing various types of motion can be used in drives of process equipment in numerous industries: chemical and food (mixers), oil refining (pumping units for crude production), mechanical engineering (compressors, pumps, automated machines), and others. The conducted kinematic studies of the planetary mechanism and their experimental analysis are needed for further dynamic and force investigations, as well as for the design of drives based on the proposed transmission.

Determination of kinematic parameters of spatial articulated crank-slide mechanism by projectionmethod

Crank-slide four-link lever mechanism serves to convert one type of rotary motion into another translational motion. This mechanism is one of the most common, it is the main mechanism in piston machines (internal combustion engines, compressors, pumps). Recently, work has been underway to introduce spatial crank-slider mechanisms in different machines in which the crank rotates in one plane and the slider moves in a straight line crossing this plane at some angle. Mechanisms of this type are going to be introduced in different piston and sewing machines in order to make them as compact as possible. In these mechanisms, the movable joints are cylindrical and spherical hinges, the connecting rod in this case has free rotation around its longitudinal axis and this gives the mechanism an additional second degree of freedom in place of one. This paper describes a method of kinematic analysis of spatial articulated mechanisms that is convenient for practical use.This method is based on the projection of the calculated spatial scheme of the studied roping mechanism onto the orthogonal system of projection planes used in descriptive geometry. Using this method, you can plot the velocities and accelerations of any kind of spatial linkage.

Reliability and Sensitivity of Enode/Vmaxpro Sensor for Muscle Power Assessment.

(1) Background: Regardless of the level of physical activity, performance monitoring is a valuable component of the training process. The aim of this research was to assess the reliability and sensitivity of parameter measurements using the Enode/Vmaxpro sensor. (2) Methods: Metric characteristics were examined for average velocity, peak velocity, average power, peak power, movement length, and movement duration. Twenty-seven participants (15 men and 12 women) underwent body composition analysis and testing on a combined leg extension/leg curl machine, performing the exercises with each leg individually under a 30% body mass load. Descriptive statistics, reliability analyses, and difference analyses were conducted to evaluate repeatability and sensitivity levels. The significance threshold was set at the level 0.05. (3) Results: Reliability parameters were found to be statistically significant, both overall (ICC: 0.937-0.991) and separately for men (ICC: 0.899-0.984) and women (ICC: 0.908-0.990). Sensitivity was confirmed through significant differences based on sex (p = 0.000), activity level (p = 0.000), and movement type (p = 0.000). No statistically significant differences were observed between right and left leg performance. (4) Conclusions: The findings suggest that the Enode/Vmaxpro sensor demonstrates sufficient sensitivity and reliability for muscle power testing in biomechanics and sports diagnostics.

EARTHQUAKES FELT in the NORTH CAUCASUS in 2020: VERKHNE-FIAGDON EARTHQUAKE on JANUARY 26, 2020 with KR=11.2, I0=5 and JEYRAKH EARTHQUAKE on MAY 24, 2020 with KR=10.6, I0=4

In 2020, two significant earthquakes were registered in the south of the Republics of North Ossetia-Alania and Ingushetia: on January 26 with KR=11.2 and on May 24 with KR=10.6. The earthquakes occurred in different seismotectonic conditions. The source of the first event was formed within the Adaykom Kazbek fault, and the source of the second event – within the Karmadon zone of occurrence of earthquake sources. The January 26 earthquake, named the Verkhne-Fiagdon, became the strongest instrumentally recorded earthquake in North Ossetia since the beginning of seismological observations on this territory. It was felt in 19 settlements with the intensity from 2 to 4–5. The calculated intensity in the epicenter is estimated as I0=5. According to the focal mechanism solution, the Verkhne-Fiagdon earthquake occurred under the influence of prevailing compres sive stress. The type of movement in the focus is reverse fault with significant strike-slip component. The earth quake on May 24, named the Jeyrakh earthquake, was felt in 12 settlements with intensity from 2 to 4. Tensile stresses oriented in a south-west direction prevailed in the focus. The type of movement is a normal fault on both planes, with minor strike-slip components. Information on historical seismicity in the focal zones of both earth quakes is given for the last 150 years.

Felt earthquake on March 4, 2024, Mw=5.0, in the Kyungey-Ala-Too ridge

The paper presents the results of the analysis of instrumental and macroseismic data of the strong Kungey earthquake on March 4, 2024, on the border of Kyrgyzstan and Kazakhstan in the Kemin-Chilik fault area. The hypocenter of the earthquake is confined to the focal zone of the catastrophic Kemin earthquake of 1911 with Mw=8.2. The earthquake of March 4, 2024 occurred under the action of submeridional near-horizontal compression, which is typical for the sources of the Northern Tien Shan. The type of motion in the source along the steeply dipping plane NP1 of southwestern strike is a reverse type of motion with a left-sided strike-slip component, along the plane of an eastern strike is a thrust with a right-sided strike-slip component. Before the Kungey earthquake, a ring-shaped seismicity structures formed by earthquakes with depths of up to 33 km, which is a prediction’s factor for strong crustal earthquakes. The earthquake was felt in Almaty (Kazakhstan) and its suburbs with an intensity of 5 points on the MSK-64 scale and had the most significant impact on the megapolis after the Baysorun earthquake of 1990. Data on the macroseismic impact of the Kungey earthquake in Kazakhstan and Kyrgyzstan were collected. An analysis of the records of strong motion instruments based on data from Central Asian stations was carried out.