The purpose of this study is to describe and analyze Integrated Self-Sufficient City development policy instrument. This research was conducted with qualitative methods, data presentation is done through interviews, documentation and observation, while data analysis is performed by adopting the thought Miles, Huberman and Saldana (2014) by using interactive methods of analysis models.The results of this study concluded that “policy instruments Integrated Self-Sufficient City construction on transmigration area in Northern Bengkulu district proven cannot be implemented to the fullest”. Conclusion of the existing findings as described from the evidence that there are the following. Recommendations are: The success of Integrated Self-Sufficient City policy implementation can be perceived by the public and appropriate goal would initially need to do various strengthening and improvement of the implementation of the policy. So that the reinforcement can be realized if the strengthening of institutional functions in every sector can formulate policies are clear and measurable. To the researchers have several recommendations that may be referenced regarding synergize the various types of policy instruments by taking into account local conditions and regulations as well as regional development.Integrated Self-Sufficient City promoting policies to all working Units local goverment that Integrated Self-Sufficient City program development across sectors that require coordination both at central and regional level.