The effects of a low-external-input soil fertility enhancement solution – hereafter termed ‘nitrolimigation’ were examined, as a preferred technique of applying nitrogen and calcium in the “Acid Sands” soils of southern Nigeria. Two types of nitrogenous fertilizer sources [urea and liquid pig manure (LPM)] and two types of lime {limestone (CaCO3) and hydrated lime [Ca(OH)2]} were used both in greenhouse and in field experiments at varying levels: Urea [CO (NH2)2] 0, 40, 50, 80, 100, 120, and 150 kg ha−1; lime 0, 0.1, 0.3, 0.5, 1.0, 5.0, and 10.0 metric tonnes per hectare (t ha−1) and LPM 0, 30, 60, 90, and 120 t ha−1. The rates were arranged factorially and laid out in randomized complete block design (RCBD). The results indicated that combining lime at 9 t ha−1 and LPM at 90 t ha−1 in irrigation water had significant (P < 0.01) positive effects on the fertility status of the “Acid Sands” soils and growth of okra- Abelmoschus esculentus, the test crop. When urea was combined with hydrated lime, it reduced acidity and provided nutrient balance in the Acid Sands of Calabar. Total nitrogen was significantly (P < 0.01) boosted from 0.05 to 0.11%, base saturation (BS) from 46 to 62%, and exchange acidity was reduced from 2.93 to 1.35 cmol kg−1. Combining urea (46-0-0) at 80 kg ha−1 with lime (CaCO3) at 5 t ha−1 raised the soil pH from 4.4 to 7.1. Exchange acidity was reduced from 0.8 cmol kg−1 to a negligible value, but electrical conductivity was improved from 170.7 to 291.9 μS cm−1. When LPM and lime were combined, organic carbon was increased from 2.75 to 2.93%, BS was increased from 46.72 to 75.19%, and pH was raised from 6.0 to 6.73. Plant height was increased from 9.5 to 16.9 cm while mean number of leaves was also increased from 5.6 to 6.3 only with lower level of lime (3 t ha−1) and LPM at 90 t ha−1. Of the nitrogen and calcium sources, LPM and limestone were better at 120 t ha−1 and 9 t ha−1, respectively, to offset soil acidity, boost nutrient availability, and provide balanced nutrition to arable crops grown on the “Acid Sands” of southern Nigeria.