Type Of Language Impairment Research Articles

Brain networks' functional connectivity separates aphasic deficits in stroke.

To investigate whether different language deficits are distinguished by the relative strengths of their association with the functional connectivity (FC) at rest of the language network (LN) and cingulo-opercular network (CON) after aphasic stroke. In a group of patients with acute stroke and left-hemisphere damage, we identified 3 distinct, yet correlated, clusters of deficits including comprehension/lexical semantic, grapheme-phoneme knowledge, and verbal executive functions. We computed partial correlations in which the contributions of a behavioral cluster and network FC of no interest were statistically regressed out. We observed a double dissociation such that impairment of grapheme-phoneme knowledge was more associated with lower FC of the LN within the left hemisphere than lower FC of the CON, whereas verbal executive deficits were more related to lower FC of the CON than the LN in the left hemisphere. Furthermore, the specific association between language deficits and FC was independent of the amount of structural damage to the LN and CON. These findings indicate that after a left-hemisphere lesion, the type of language impairment is related to the abnormal pattern of correlated activity in different networks. Accordingly, they extend the concept of a neuropsychological double dissociation from structural damage to functional network abnormalities. Finally, current results strongly argue in favor of the behavioral specificity of intrinsic brain activity after focal structural damage.

Word recognition and nonword repetition in children with language disorders: the effects of neighborhood density, lexical frequency, and phonotactic probability.

The effects of neighborhood density (ND) and lexical frequency on word recognition and the effects of phonotactic probability (PP) on nonword repetition (NWR) were examined to gain insight into processing at the lexical and sublexical levels in typically developing (TD) children and children with developmental language problems. Tasks measuring NWR and word recognition were administered to 5 groups of children: 2 groups of TD children (5 and 8 years old), children with specific language impairment (SLI), children with reading impairment (RI), and children with SLI+RI (all 7-8 years old). High ND had a negative effect on word recognition in the older TD children and in the children with RI only. There was no ND effect in the younger children or in the children with SLI, who all had lower receptive vocabulary scores than the age-matched TD children and the RI groups. For all groups, NWR items with low PP were more difficult to repeat than items with high PP. This effect was especially pronounced in children with RI. Both the stage of vocabulary development and the type of language impairment (SLI or RI) impact the way ND and PP affect word recognition and NWR.

High Prevalence of Early Language Delay Exists Among Toddlers With Neonatal Brachial Plexus Palsy

AimAn association of language impairment with neonatal brachial plexus palsy has not been reported in the literature. The current treatment paradigm for neonatal brachial plexus palsy focuses on upper extremity motor recovery with little formal assessment of other aspects of development, such as language. We performed a cross-sectional pilot study to investigate early language delay prevalence in toddlers with neonatal brachial plexus palsy and potential neonatal brachial plexus palsy–related factors involved. MethodTwenty toddlers with neonatal brachial plexus palsy were consecutively recruited (12 males and eight females; mean age, 30 months). Preschool Language Scale Score (4th edition), demographics, and socioeconomic status were collected. Neonatal brachial plexus palsy–related factors such as palsy side, treatment type, Narakas grade, muscle Medical Research Council score, and Raimondi hand score were reported. Student t test, chi-square test, or Fisher exact test were applied. Statistical significance level was established at P < 0.05. ResultsOf study participants, 30% had language delay, whereas the prevalence of language delay in the population with normal development in this age range was approximately 5-15%. InterpretationWe observed high language delay prevalence among toddlers with neonatal brachial plexus palsy. Although our subject sample is small, our findings warrant further study of this phenomenon. Early identification and timely intervention based on type of language impairment may be critical for improving communication outcome in this population.

Why is it difficult to predict language impairment and outcome in patients with aphasia after stroke?

One of the most devastating consequences of stroke is aphasia. Communication problems after stroke can severely impair the patient's quality of life and make even simple everyday tasks challenging. Despite intense research in the field of aphasiology, the type of language impairment has not yet been localized and correlated with brain damage, making it difficult to predict the language outcome for stroke patients with aphasia. Our primary objective is to present the available evidence that highlights the difficulties of predicting language impairment after stroke. The different levels of complexity involved in predicting the lesion site from language impairment and ultimately predicting the long-term outcome in stroke patients with aphasia were explored. Future directions and potential implications for research and clinical practice are highlighted.

The genetics and neuropathology of frontotemporal lobar degeneration.

Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders characterized by disturbances of behavior and personality and different types of language impairment with or without concomitant features of motor neuron disease or parkinsonism. FTLD is characterized by atrophy of the frontal and anterior temporal brain lobes. Detailed neuropathological studies have elicited proteinopathies defined by inclusions of hyperphosphorylated microtubule-associated protein tau, TAR DNA-binding protein TDP-43, fused-in-sarcoma or yet unidentified proteins in affected brain regions. Rather than the type of proteinopathy, the site of neurodegeneration correlates relatively well with the clinical presentation of FTLD. Molecular genetic studies identified five disease genes, of which the gene encoding the tau protein (MAPT), the growth factor precursor gene granulin (GRN), and C9orf72 with unknown function are most frequently mutated. Rare mutations were also identified in the genes encoding valosin-containing protein (VCP) and charged multivesicular body protein 2B (CHMP2B). These genes are good markers to distinguish underlying neuropathological phenotypes. Due to the complex landscape of FTLD diseases, combined characterization of clinical, imaging, biological and genetic biomarkers is essential to establish a detailed diagnosis. Although major progress has been made in FTLD research in recent years, further studies are needed to completely map out and correlate the clinical, pathological and genetic entities, and to understand the underlying disease mechanisms. In this review, we summarize the current state of the rapidly progressing field of genetic, neuropathological and clinical research of this intriguing condition.

Semi-spontaneous oral text production: Measurements in clinical practice

Functionally relevant assessment of the language production of speakers with aphasia should include assessment of connected speech production. Despite the ecological validity of everyday conversations, more controlled and monological types of texts may be easier to obtain and analyse in clinical practice. This article discusses some simple measurements for the analysis of semi-spontaneous oral text production by speakers with aphasia. Specifically, the measurements are related to the production of verbs and nouns, and the realization of different sentence types. The proposed measurements should be clinically relevant, easily applicable, and linguistically meaningful. The measurements have been applied to oral descriptions of the ‘Cookie Theft’ picture by eight monolingual Norwegian speakers, four with an anomic type of aphasia and four without any type of language impairment. Despite individual differences in both the clinical and the non-clinical group, most of the measurements seem to distinguish between speakers with and without aphasia.

Assessment of linguistic abilities in Italian children with Specific Language Impairment

This study aims to describe in detail the linguistic skills of a large group of SLI participants. Particular attention is paid to the analysis of age-related effects on their linguistic performance and to whether a linguistic assessment of a narrative task can capture language impairments that might not be adequately pointed out by standardized neuropsychological tests assessing linguistic functions. The narratives produced by 62 children diagnosed with SLI with mixed expressive–receptive disorders were compared to those provided by a group of 195 children with Typical Language Development matched for chronological age and level of formal education. Furthermore, an age-related groups’ performance analysis has been performed in order to determine possible correlations between patients’ ages and types of language impairment. The SLI participants produced an amount of words comparable to that produced by the control group, albeit in a simpler fashion, as their narratives were teeming with omissions and/or substitutions of bound and free morphemes. These data suggest that the domains of morphosyntax and syntax were particularly impaired.

Editorial: Why a diversity of methods are required to understand childhood disorders

Editorial: Why a diversity of methods are required to understand childhood disorders

Primary progressive aphasia and Alzheimer’s dementia: Evolution, pathology and type of language impairment

Primary progressive aphasia and Alzheimer’s dementia: Evolution, pathology and type of language impairment

Longitudinal analyses of risk‐disorder pathways: the key to early identification and targeted intervention

Longitudinal analyses of risk‐disorder pathways: the key to early identification and targeted intervention

Assessment of pragmatic difficulties and socio‐emotional adjustment in practice

In professional practice, psychologists and other professionals such as therapists and teachers receive referrals of many children who present with social, emotional and behavioural difficulties that are difficult to understand and assess. The problems of some of these children may stem from pragmatic difficulties in communication. This paper reports the results of a study on the use of checklists in professional practice to assist in the identification of these difficulties. (1) To ascertain whether two checklists, Bishop's (1998) Children's Communication Checklist and Goodman's (1997) Strengths and Difficulties Questionnaire, would discriminate between groups of children diagnosed as having autism, autistic spectrum disorder/Asperger's syndrome, pragmatic difficulties and children with other types of specific language impairment. (2) To investigate whether specific aspects of pragmatic difficulties can be identified as relating to difficulties in peer relationships. (3) To investigate whether ratings of pragmatic difficulties are related solely to difficulties in social relations or whether other aspects of socio-emotional adjustment are also affected. The Children's Communication Checklist and the Strengths and Difficulties Questionnaire were completed by the teachers and other professionals working with a sample of children (n = 38) with a range of types of communication difficulty and being educated in schools run by one English Local Education Authority. Analyses of variance indicated that the scores for pragmatic competence and socio-emotional adjustment difficulties were useful in discriminating between groups of children with diagnoses of autism or autistic spectrum disorder, Asperger's syndrome, and other types of language impairment. No specific pragmatic correlates of social interactional difficulties were found, but ratings of hyperactivity were significantly correlated with pragmatic difficulties. The two checklists if used together provide useful information on the profiles of strengths and weaknesses of children with a range of communication and or emotional/behavioural difficulties. The use of both checklists in this study demonstrated the differential profiles of pragmatic competence and socio-emotional adjustment of children with different types of communication difficulty.

Language Impairment and Generative Analysis

This article deals with different types of language impairment from the perspective of generative grammar. The paper focuses on syntactic deficiencies observed in aphasic and SLI (specific language impairment) patients. We show that the observed ungrammatical structures do not appear in a random fashion but can be predicted by that theory of universal sentence structure which posits a strict hierarchy of its constituent parts. The article shows that while the hierarchically lower elements remain unaffected, the higher positions in the hierarchy show various degrees of syntactic impairment. The paper supports the implementation of recent developments in the field of generative grammar with the intention of encouraging further theoretical, experimental and therapeutic research in the field.

The Utility of the Differential Abilities Scales with Specific Language-Impaired Preschoolers

The purpose of this study was to examine the utility of the Differential Ability Scales (DAS) in distinguishing preschoolers with specific language impairment (SLI) and specific subtypes of language delays. Three hundred forty-eight language-impaired preschoolers' response patterns across DAS General Conceptual Ability (GCA), Ability cluster, and subtest scores were compared to response profiles of 57 preschoolers without language impairment as well as the standardized mean. Participants' specific type of language impairment (Articulation, Expressive, Receptive, Pragmatic, Expressive-Receptive, Expressive-Articulation, Receptive-Articulation, and Articulation-Pragmatic) was then compared to their response patterns. Results indicated that, in general, SLI preschoolers had significantly lower GCA, Verbal Ability, Nonverbal Ability, and subtest scores on the DAS compared to preschoolers without language impairment. However, different response patterns across the GCA, Ability clusters, and subtests emerged depending on the SLI subtype. SLI children with Articulation-only impairments tended to score higher on Ability Cluster and subtest scores, whereas children with Receptive and Expressive-Receptive impairment scored lowest. Discriminant analysis revealed that subtype profiles could predict SLI subtype in 26% to 38% of the cases. Finally, factor analysis indicated a new factor structure for both younger and older preschool batteries, suggesting that practitioners working with the SLI-referred population should carefully consider the utility of the original DAS factors.

High incidence of language disorder in children with focal epilepsies.

To investigate the relationship between the presence of language disorder, type of epilepsy, and epileptic seizures in childhood, language levels, types of language impairment, and aetiologies were examined in 109 children, aged between 5 and 17 years, attending a national children's epilepsy assessment unit over a 4-year period. There were 70 males and 39 females. Median age was 11 years 4 months (range 5 to 18 years 9 months). In addition to neurological assessment, simultaneous video and EEG monitoring and prolonged ambulatory EEG, each child underwent a comprehensive series of multidisciplinary tests, including intelligence, language, and communication assessments. Classification of seizures and epilepsy syndromes was agreed in conference by a physician specializing in childhood epilepsies, a paediatric neurologist, and a neuropsychiatrist. Other test procedures were administered by a speech and language pathologist with assistance from a neuropsychologist when relevant. Level of language disability in these children was associated with a range of aetiological factors. Evidence was found of a significant number of associations between focal epilepsies, certain seizure types, and language disorder. Of the 46 (42.2%) children with language disorders in the research sample, 30 had localization-related epilepsies and a further three had epilepsies which were undetermined as to whether focal or generalized. Children with focal epilepsies were 30% more likely to have language disorder than other language disability subtypes. The research demonstrated a clear though often subtle association between focal (localization-related) epilepsy and language disorder, indicating an increased risk in this patient group. Children with simple or complex partial seizures were more likely to have language disorder than other language disability subtypes; they also tended to have the lowest number of seizure types per case. This is of importance to clinicians managing children with epilepsy and has implications for their educational and social welfare.

The Prevalence of Communication Impairment in Adults: A Summary and Critical Evaluation of the Literature

This paper seeks to summarise and evaluate research into the prevalence of communication impairment in adults. The results of prevalence research in this area depend upon the type of language impairment and the population investigated. As well, the study design has an influence on the eventual prevalence result. Despite these constraints, trends and ranges of prevalence data are described for communication impairment in general and for most specific types of communication impairment. The implications of the prevalence literature for health resource planning are discussed.

HYPERPHAGIA IN FOSTER CARE CHILDREN

Hyperphagia, defined as excessive appetite, characterized by a grossly increased intake of and constant searching for food, was noted in a group of 15 foster children evaluated for developmental impairment or behavioral management problems. Caretakers described these children's eating habits as showing a driven quality without achievement of satiety or pleasure. These behaviors were evident when the children first came into foster care and often persisted over time. The hyperphagia did not result in excess weight gain; only one child achieved substantial increase in weight on followup. The children in the group tended to have mild degrees of intellectual impairment, while emotional and behavioral problems were frequent and severe. 80% of the children functioned in the mildly retarded range; 53% had Attention Deficit Disorder with Hyperactivity and 47% had a form of Pervasive Developmental Disorder. Speech and language problems were common; 73% had articulation disorders and 40% other types of language impairment. Sixty percent of the biological mothers were known to have histories of alcohol and/or drug abuse. Though eating disorders have been described among mentally retarded individuals, there is no report of long-term hyperphagia among children with mild mental retardation with the exception of Prader-Willi syndrome. Its presence signals the existence of substantial childhood psychopathology as well as the increased risk for deviant behaviors in adulthood.