Types Of Wound Dressings Research Articles

Biocompatible and biodegradable wound dressings on the basis of seaweed polysaccharides (review of literature)

The review presents the characteristics of modern biocompatible and biodegradable wound dressings on the basis of seaweed polysaccharides (carrageenans of red algae, fucoidans and alginates of brown algae, ulvans of green algae) and notes the key physicochemical and biological properties that are important for constructing wounds dressings. There are information on various types of wound dressings and results of experimental and clinical tests of dressings in the treatment of wounds of various origins. Particular attention is paid to hydrogel dressings, since hydrogels meet the basic requirements for an ideal wound dressing, and many marine polysaccharides are able to form hydrogels.

Wound Dressings – A Practical Review

There are currently thousands of wound dressing products and materials available on the market. Despite the wide selection, there is no universally superior dressing, which prompts healthcare providers to choose materials that are most suitable to each particular case. This review provides an overview of various types of wound dressings, suggested uses, and recent advancements. Modern dressings have evolved to encompass an expansive array of semipermeable films and foams, hydrofibers, hydrogels, hydrocolloids, and alginates. Recent studies have investigated new technologies such as electrospun biopolymer nanofibers to create sprayable dressings while also exploring new roles for traditional materials such as honey and other non-synthetic derivatives. Wound presentations are diverse and require unique materials to best accommodate their respective healing processes. Future research is aimed at improving versatility and effectiveness of existing wound dressings while also investigating innovative therapeutic approaches to better manage challenging, non-healing wounds.

Design and fabrication of an instrument to evaluate characteristics of fluid handling capacity of wound care dressings

A novel instrument has been developed to determine the fluid handling capacity of different types of wound dressings, irrespective of their structure and composition. The instrument is developed with custom built wound bed/plate with specially designed path to control the amount and flow rate of wound exudates, simulating the actual wound alike conditions. The instrument has provision to apply compression / pressure over wound dressing while testing to similar realtime compression / pressure applied on wound dressing. The study was carried out using different types of commercially available wound dressings. It is found that the developed instrument is able to test different types of dressings effectively for fluid handling capacity. The results obtained by new instrument are found comparable with the existing methods. The existing methods give only single value of fluid handling capacity at the defined hour as compared to the new instrument which gives online continuous results from zero to 48 h. This real time data may be useful for defining the effectiveness of dressings at a particular time interval. The data obtained from the instrument can also be used to know the saturation point and change with time for a particular dressing. The repeatability of results are also proven. Also the instrument is able to test fluid handling capacity of dressings with and without pressure.

Negative pressure wound therapy for surgical wounds healing by primary closure.

Negative pressure wound therapy for surgical wounds healing by primary closure.

Negative pressure wound therapy for surgical wounds healing by primary closure.

Negative pressure wound therapy for surgical wounds healing by primary closure.

Advanced nursing recovery therapy in the field of nanotechnology based on tetracycline hydrochloride type drugs

With the development of wound care theory and practice methods, the development of new materials and the improvement of sustained release and controlled release technologies, medical dressings will develop in the direction of multi-functionality, diversification and intelligence. This has also promoted the development of clinical care, better service for wound patients, new dressings, and new methods for wound care. Among many new dressings, nanotechnology-based polymer nanogels have good application prospects due to their good water retention properties and micelle stability properties. At present, a large number of researchers have developed a variety of wound care materials, which are widely used in clinical settings. However, due to the shape of the material or its characteristics, the mechanism of action of many materials has not been studied in detail. How to prepare a new type of wound dressing, which has multiple functions - integrating haemostasis, bacteriostatic, stimulating cell division and differentiation, accelerating tissue healing, moisturising and phlegm, etc., so as to achieve a good evaluation of patients' post-care recovery is. China's long-standing and urgent problem in the medical device market. Therefore, this study used the tetracycline hydrochloride drug doxycycline as an antibiotic drug for nano-modified dressings. Under the theoretical guidance of the interaction between wound healing and pH of microenvironment, a polyethylene glycol (PEG) modified PEG-doxycycline hydrogel nanocomposite dressing was prepared to study the stability of nanoparticles in the dressing. Physical and pH responsiveness, swelling behaviour of composite dressings, and physicochemical properties of drug release behaviour were studied. At the same time, in order to study the effect of the PEG-doxycycline nanocomposite hydrogel on the recovery of wound care in patients, this study applied the composite nano dressing to the clinic. Through the comparative study of patients' quality of life, wound healing, nursing satisfaction and treatment effect, the innovative application of tetracycline hydrochloride in the recovery of wound care of patients under nanotechnology is realised. The results of this study indicate that PEG-doxycycline nanocomposite hydrogel prepared under the guidance of nanotechnology can promote wound healing, shorten hospital stay and reduce complications. At the same time, the use of the dressing can also reduce the work of nursing, alleviate the suffering of the patient, improve the comfort of the patient, and greatly improve the nursing effect and effect on the patient. This has certain promotion and research value for the implementation of continuous nursing methods for patients with chronic wounds, which can be popularised in clinical practice.

Chitosan-calcium alginate dressing promotes wound healing: A preliminary study.

Dressings are necessary during the process of wound healing. Since the early 1980s, several types of wound dressings have been produced, but they cannot always take into account some effects include antibacterial effect, wound healing promotion, and other properties. In this study, we would like to develop an effective dressing with the above properties, especially accelerating wound healing effect. A chitosan-calcium alginate dressing (CCAD) was developed by coating mixture of chitosan with high-low molecular weight on calcium alginate dressing (CAD). We investigated the structural characteristics of CCAD with Fourier-transform infrared spectroscopy (FTIR) and electron microscopy. The cytotoxicity and antibacterial property were evaluated in vitro using CCK-8 and inhibition zone method. Moisture retention was tested on the skin of Sprague-Dawley (SD) rats, and wound healing studies were performed on a full-thickness skin wound model in SD rats. CCAD showed good moisturizing and antibacterial properties with no cytotoxicity. CCAD could inhibit inflammation by decreasing IL-6, and it could also promote angiogenesis by increasing VEGF, resulting in better wound healing than CAD. CCAD is a better choice in wound care due to its antibacterial property, biocompatibility, moisture retention, healing promotion, and non-cytotoxicity characteristics.

Modern Wound Dressings and their Application

Introdution: Wound healing is a complex and dynamic process, which requires to be prepared a suitable environment to promote healing process. Wound dressing is one of the most important external factors affecting the wound healing process. With the advancement in technology, more than 1000 types of modern wound dressings have been developed. Wound dressings are either based on natural materials or on the basis of synthetic and chemical materials. In addition to the protective and covering role, which modern wound dressings play, they have a chemical and physical interaction with wound bed addition. They carry antibiotics, drugs and nanoparticles and play an important role in maintaining moisture or hydration the wound; all of these factors can facilitate the wound healing process. In this study, the wound healing process and the properties of wound dressings were presented first and then the types of wound dressings and their applications were investigated. This study, with comprehensive information on the types of modern wound dressings and their advantages and drawbacks, will help a physician in the proper selection of an appropriate wound dressing.

In-situ characterization of the bacterial biofilm associated with Xeroform™ and Kaltostat™ dressings and evaluation of their effectiveness on thin skin engraftment donor sites in burn patients

Biofilm forms when bacteria surrounded by an extracellular matrix aggregate on a surface. It can develop on many surfaces, including wound dressings; this can be particularly nefarious for burn patients undergoing skin grafting (autograft) for burn wound coverage as they often suffer from compromised immune system function. Autograft donor sites are particularly vulnerable to biofilm formation; as such, timely healing of these sites is essential. Our aim was to apply scanning electron microscopy to compare the efficacy of two types of wound dressings in preventing the formation of bacterial biofilm on burn patient skin graft donor sites. One dressing contained bismuth tribromophenate at a concentration of 3% which confers it bacteriostatic properties (Xeroform™). The other was an absorptive alginate calcium sodium dressing (Kaltostat™). Samples of each wound dressing, which were in contact with the skin graft donor site, were prepared for analysis under the scanning electron microscope (SEM) using an original method developed by our research group that aims to maintain the integrity of the biofilm microstructure. Samples prepared by this method were then analyzed using SEM, which allowed the characterization of biofilm and the evaluation of bacterial density on the studied dressing samples. To this day, this imaging technique has been rarely employed for dressing analysis and this is the first time that it is employed for in situ biofilm visualization for this particular application.

Negative pressure wound therapy for surgical wounds healing by primary closure.

Negative pressure wound therapy for surgical wounds healing by primary closure.

Absorption Capacity of Wound Dressings: A Comparative Experimental Study.

In this study, absorption capacity of the most commonly used types of wound dressings was measured with an objective, quantifiable, and easily reproducible method. The use of objective measurements allowed us to perform an objective comparison of the capacity of the different types of dressings. An experimental study was performed, in which the absorptive capacity of polyurethane foams, alginate, hidrofiber, and hydrocolloid dressings was measured by using a methodology designed by the researchers. Polyurethane foams showed a higher absorption capacity than hidrofibers, alginates, and hydrocolloids when using a similar surface of dressing. A modification of dressing size after saturation was also observed, increasing its size in the case of foams and decreasing or maintaining it in the case of hidrofibers, alginates, and hydrocolloids. The results of this study show a better wound exudate management for polyurethane foams. However, when deciding which dressing to use for a specific wound, absorption capacity is not the only quality that should be taken into account, as other properties should also be considered.

Evaluation of a two-stage antibacterial hydrogel dressing for healing in an infected diabetic wound.

Various types of wound dressings have been used to treat complex infections in diabetes mellitus. This study is the first to evaluate the healing effects using a two-stage dressing in infected diabetic wounds. A two-stage antibacterial hydrogel dressing (two-stage dressing) was established with two time phases, an antibacterial phase and a drug release phase. We established each phase by using a swelling and rate of drug release test. These results suggested that the antimicrobial phase is activated as soon as the two-stage dressing attaches to the skin. The drugs in the drug release layer of the dressing were released to a greater extent than expected 20-36 h after attachment to the skin, likely due to extensive water absorption. Histological analysis and measurement of vascular endothelial growth factor expression through in vivo testing suggested that the benefits of a two-stage dressing include rapid antibacterial properties, sustained drug release, and promotion of wound healing through cell proliferation as compared with the traditional composite antibacterial hydrogel dressing. Further in vivo tests confirmed that separation of the antibacterial and drug-releasing properties, along with biocompatibility and rapid wound closure rates made two-stage dressings suitable for healing of infected wounds. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1808-1817, 2017.

Silver‐based wound dressings reduce bacterial burden and promote wound healing

Various types of wound dressings have been designed for different purposes and functions. Controlling bacterial burden in a wound during the early phase is important for successful wound repair. Once bacterial burden is under control, the active promotion of wound healing is another important factor for efficient wound healing. This study investigated the potential of three silver-containing dressings, namely KoCarbonAg(®) , Aquacel(®) Ag and Acticoat 7, in reducing bacterial survival and promoting wound healing. The ability of these dressings to block the entry of bacteria from external environment and retain intrinsic bacteria was studied in vitro. In addition, the study used a rat model to compare the healing efficiencies of the three dressings and investigate the quantity of collagen synthesis in vivo. In vitro results indicated that the silver-containing dressings prevented bacterial growth in wounds by blocking the entry of external bacteria and by retaining the bacteria in the dressing. In vivo study indicated that reduction in bacterial burden accelerated wound healing. Wounds treated by the silver-containing dressings showed better healing than those treated with gauze. Moreover, KoCarbonAg(®) further accelerated wound healing by promoting collagen synthesis and arrangement.

Therapeutic Potential of Noble Nanoparticles for Wound Repair.

IntroductionNanoparticles made of noble metals, such as gold and silver, have a great potential to be effectively employed for wound management. The nano-size of such particles provides an opportunity to enlarge the contacting area, which results in more effective anti-bacterial action and faster wound repair. It must be noted that the shape of noble nanoparticles might play a crucial role in the manifestation of their anti-microbial properties. The modern state of technology allows fabrication of the nanoparticles with the desired shape and physical properties. In order to provide efficacy and close contact with the wound, the noble nanoparticles can be incorporated into a special matrix made of a cryogel (based on polymethyl methacrylate). This combination might serve as a foundation for developing completely new types of wound dressing.Materials and methodsWe have developed a few methods for synthesizing gold and silver nanoparticles of different shapes and sizes. After fabrication of metallic nanoparticles, they were characterized by using Tunneling Electron Microscopy (TEM) and Malvern Zetasizer system in order to determine the average population size and consistency. The silver nanoparticles was synthesized using sodium borohydride reduction of silver nitrate. The synthesis of gold nanoparticles was conducted by using the Turkevich method.ResultsWe have developed a synthetic cryogel based on polyacrylamide (by cryogelation reaction) at several temperatures. At the second step, we developed a method for conjugating fabricated gold and silver nanoparticles to the surface (or pores) of cryogel through covalent bonds so they can provide antibacterial action within the wound. By following the developed protocol, we were able to obtain an approximate cryogel layer (1 cm thickness) with embedded gold and silver nanoparticles. This conjugate was analyzed and confirmed using Scanning Electron Microscopy (SEM) and TEM.DiscussionThe obtained results indicate the feasibility of the fabrication of a novel type of wound dressing. At the next step, we are planning to elucidate the bio-compatibility of the combination of cryogel and nanoparticles. Moreover, anti-bacterial properties of this new type of wound dressing will be analyzed.

Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention.

Indications for the use of negative pressure wound therapy (NPWT) are broadening with a range of systems now available on the market, including those designed for use on clean, closed incisions and skin grafts. Reviews have concluded that the evidence for the effectiveness of NPWT remains uncertain, however, it is a rapidly evolving therapy. Consequently, an updated systematic review of the evidence for the effects of NPWT on postoperative wounds expected to heal by primary intention is required. To assess the effects of NPWT on surgical wounds (primary closure, skin grafting or flap closure) that are expected to heal by primary intention. We searched the following electronic databases to identify reports of relevant randomised clinical trials:the Cochrane Wounds Group Specialised Register (searched 28 January 2014); the Cochrane Central Register of Controlled Trials (CENTRAL; 2013, issue 12); Database of Abstracts of Reviews of Effects (2013, issue 12); Ovid MEDLINE (2011 to January 2014); Ovid MEDLINE (In-Process & Other Non-Indexed Citations 24 January 2014); Ovid EMBASE (2011 to January 2014 Week 44); and EBSCO CINAHL (2011 to January 2014). We conducted a separate search to identify economic evaluations. We included trials if they allocated patients to treatment randomly and compared NPWT with any other type of wound dressing, or compared one type of NPWT with a different type of NPWT. We assessed trials for their appropriateness for inclusion and for their quality. This was done by three review authors working independently, using pre-determined inclusion and quality criteria. In this first update, we included an additional four trials, taking the total number of trials included to nine (785 participants). Three trials involved skin grafts, four included orthopaedic patients and two included general surgery and trauma surgery patients; all the included trials had unclear or high risk of bias for one or more of the quality indicators we assessed. Seven trials compared NPWT with a standard dressing (two of these were 'home-made' NPWT devices), one trial compared one 'home-made' NPWT with a commercially available device. In trials where the individual was the unit of randomisation, there were no differences in the incidence of surgical site infections (SSI); wound dehiscence, re-operation (in incisional wounds); seroma/haematoma; or failed skin grafts. Lower re-operation rates were observed among skin graft patients in the 'home-made' NPWT group (7/65; 10.8%) compared to the standard dressing group (17/66; 25.8%) (risk ratio (RR) 0.42; 95% CI 0.19 to 0.92). The mean cost to supply equipment for VAC® therapy was USD 96.51/day compared to USD 4.22/day for one of the 'home-made' devices (P value 0.01); labour costs for dressing changes were similar for both treatments. Pain intensity score was also reported to be lower in the 'home-made' group when compared with the VAC® group (P value 0.02). One of the trials in orthopaedic patients was stopped early because of a high incidence of fracture blisters in the NPWT group (15/24; 62.5%) compared with the standard dressing group (3/36; 8.3%) (RR 7.50; 95% CI 2.43 to 23.14). Evidence for the effects of negative pressure wound therapy (NPWT) for reducing SSI and wound dehiscence remains unclear, as does the effect of NPWT on time to complete healing. Rates of graft loss may be lower when NPWT is used, but hospital-designed and built products are as effective in this area as commercial applications. There are clear cost benefits when non-commercial systems are used to create the negative pressure required for wound therapy, with no evidence of a negative effect on clinical outcome. In one study, pain levels were also rated lower when a 'home-made' system was compared with a commercial counterpart. The high incidence of blisters occurring when NPWT is used following orthopaedic surgery suggests that the therapy should be limited until safety in this population is established. Given the cost and widespread use of NPWT, there is an urgent need for suitably powered, high-quality trials to evaluate the effects of the newer NPWT products that are designed for use on clean, closed surgical incisions. Such trials should focus initially on wounds that may be difficult to heal, such as sternal wounds or incisions on obese patients.

Lower Extremity Ulcers

Acknowledging and addressing common features of lower extremity ulcers will allow the surgeon to heal the vast majority of leg ulcers, either surgically or nonsurgically. The involvement of a surgeon interested in lower extremity preservation ensures the patient is offered a comprehensive set of management options. The authors discuss chronic and problem wounds, incidence and epidemiology, anatomic considerations, clinical evaluation and investigative studies, and general and specific management of the main types of leg ulcer (arterial, diabetic, venous, and inflammatory). Tables describe types and causes of lower extremity ulcers, common characteristics, members of the multidisciplinary team, conditions that interfere with healing, angiosomes of the foot, components of a leg ulcer that must be removed by débridement, benefits of hyperbaric oxygen and well-performed débridement, commonly used local pedicled flaps, staging systems for diabetic foot ulcer, and classes of compression stockings. Figures illustrate angiosomes of the anterior tibial, dorsalis pedis, peroneal, posterior tibial, lateral plantar, and medial plantar arteries; interplay between bacterial levels; types of wound dressing; ulcer locations as an indication of etiology; and management of arterial insufficiency ulcers, diabetic foot ulcers, and venous stasis ulcers. This review contains 11 figures, 11 tables, and 138 references.

Lower Extremity Ulcers

Acknowledging and addressing common features of lower extremity ulcers will allow the surgeon to heal the vast majority of leg ulcers, either surgically or nonsurgically. The involvement of a surgeon interested in lower extremity preservation ensures the patient is offered a comprehensive set of management options. The authors discuss chronic and problem wounds, incidence and epidemiology, anatomic considerations, clinical evaluation and investigative studies, and general and specific management of the main types of leg ulcer (arterial, diabetic, venous, and inflammatory). Tables describe types and causes of lower extremity ulcers, common characteristics, members of the multidisciplinary team, conditions that interfere with healing, angiosomes of the foot, components of a leg ulcer that must be removed by débridement, benefits of hyperbaric oxygen and well-performed débridement, commonly used local pedicled flaps, staging systems for diabetic foot ulcer, and classes of compression stockings. Figures illustrate angiosomes of the anterior tibial, dorsalis pedis, peroneal, posterior tibial, lateral plantar, and medial plantar arteries; interplay between bacterial levels; types of wound dressing; ulcer locations as an indication of etiology; and management of arterial insufficiency ulcers, diabetic foot ulcers, and venous stasis ulcers. This review contains 11 figures, 11 tables, and 138 references.

Management of infected wounds

Treatment of infected wounds can be challenging and daunting. This article suggests a protocol for dealing with patients with such wounds and outlines options for ongoing wound management. The use of various types of wound dressings and novel forms of wound care are outlined.

Visualisation of Liquid Flow Phenomena in Textiles Applied as a Wound Dressing

Abstract The aim of this work was to visualise liquid transport in textiles. Knowledge of the transport phenomena allows for the design of textiles for various applications, e.g., comfortable to wear filtration and wound dressing. To visualise liquid transport through textiles, three test methods were explored. The first one was the high spatial resolution magnetic resonance imaging (MRI) technique (also referred to as nuclear magnetic resonance (NMR) microscopy). It allowed the observation of the pathways of liquid flow through textiles. In the second method, a thermographic camera was used to record temperature changes and assess the liquid flow in the textile. The third method was using a high-speed video camera to observe the liquid transport within the textile. Two types of textiles were studied: a double-layer knitted fabric and a woven fabric, both made from hydrophilic and hydrophobic fibres (cotton, viscose and polypropylene). The knitted fabrics were tested as a new type of wound dressing, which trans

An introduction to wound healing and dressings

The cost of managing patients with chronic wounds is rising and accounts for 3% of the total NHS budget. Despite significant advances in wound management over the last 35 years there remains little evidence of standardised practices across the country. The management of wounds is continually viewed as a challenging and costly area of practice. The challenges arise from the increasing complexity of acute and chronic wounds, which are affected by patients multiple comorbidities, resistant bacteria and an aging population. There is also a plethora of dressings available in the market place today which despite providing a wide choice can be confusing and costly if inappropriately used. This article will explore the principles of wound healing, highlighting key factors that can impact on outcomes. The main types of wound dressings will also be discussed.